PubRank

Edward G D Tuddenham

Author PubWeight™ 47.34‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Adenovirus-associated virus vector-mediated gene transfer in hemophilia B. N Engl J Med 2011 11.01
2 Mutations in VKORC1 cause warfarin resistance and multiple coagulation factor deficiency type 2. Nature 2004 5.95
3 Self-complementary adeno-associated virus vectors containing a novel liver-specific human factor IX expression cassette enable highly efficient transduction of murine and nonhuman primate liver. Blood 2005 4.23
4 Safe and efficient transduction of the liver after peripheral vein infusion of self-complementary AAV vector results in stable therapeutic expression of human FIX in nonhuman primates. Blood 2006 3.42
5 Long-term safety and efficacy of factor IX gene therapy in hemophilia B. N Engl J Med 2014 2.92
6 Codon optimization of human factor VIII cDNAs leads to high-level expression. Blood 2010 1.68
7 Pharmacodynamic resistance to warfarin associated with a Val66Met substitution in vitamin K epoxide reductase complex subunit 1. Thromb Haemost 2005 1.54
8 Autosomal dominant erythrocytosis and pulmonary arterial hypertension associated with an activating HIF2 alpha mutation. Blood 2008 1.37
9 Therapeutic levels of FVIII following a single peripheral vein administration of rAAV vector encoding a novel human factor VIII variant. Blood 2013 1.36
10 Permanent phenotypic correction of hemophilia B in immunocompetent mice by prenatal gene therapy. Blood 2004 1.30
11 Combined deficiency of factor V and factor VIII is due to mutations in either LMAN1 or MCFD2. Blood 2005 1.15
12 Complete inhibition of acute humoral rejection using regulated expression of membrane-tethered anticoagulants on xenograft endothelium. Am J Transplant 2004 1.08
13 Molecular evolution of the vertebrate blood coagulation network. Thromb Haemost 2003 0.98
14 A novel missense mutation in ABCA1 results in altered protein trafficking and reduced phosphatidylserine translocation in a patient with Scott syndrome. Blood 2005 0.92
15 Genotype-phenotype correlation in combined deficiency of factor V and factor VIII. Blood 2008 0.91
16 AAV-mediated gene transfer in the perinatal period results in expression of FVII at levels that protect against fatal spontaneous hemorrhage. Blood 2011 0.89
17 Alpha1-antitrypsin Pittsburgh in a family with bleeding tendency. Haematologica 2009 0.87
18 A common ancestral glycoprotein (GP) 9 1828A>G (Asn45Ser) gene mutation occurring in European families from Australia and Northern Europe with Bernard-Soulier Syndrome (BSS). Thromb Haemost 2005 0.83
19 Use of a non-depleting anti-CD4 antibody to modulate the immune response to coagulation factors VIII and IX. Br J Haematol 2002 0.81
20 Factor VIII - novel insights into form and function. Br J Haematol 2002 0.80
21 Menorrhagia in adolescents with inherited bleeding disorders. J Pediatr Adolesc Gynecol 2010 0.80
22 Live birth following the first mutation specific pre-implantation genetic diagnosis for haemophilia A. Thromb Haemost 2006 0.79
23 Ways to bypass a blocked tenase complex. Thromb Haemost 2006 0.77
24 Functional characterization of factor V-Ile359Thr: a novel mutation associated with thrombosis. Blood 2003 0.77
25 Identification of factor IX mutations in Iranian haemophilia B patients by SSCP and sequencing. Thromb Res 2006 0.77
26 Characterisation of lymphocyte responses to Ca2+ in Scott syndrome. Thromb Haemost 2004 0.76
27 Two novel mutations in severe factor VII deficiency. Br J Haematol 2004 0.75
28 Human congenital diseases with mixed modes of inheritance have a shortage of recessive disease. A demographic scenario? Ann Hum Genet 2011 0.75
29 Characterisation of blood coagulation factor XI T475I. Thromb Haemost 2005 0.75