PubRank

Colin Kleanthous

Author PubWeight™ 69.94‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Colicin biology. Microbiol Mol Biol Rev 2007 5.54
2 Im7 folding mechanism: misfolding on a path to the native state. Nat Struct Biol 2002 3.15
3 Structural and functional analysis of SGT1 reveals that its interaction with HSP90 is required for the accumulation of Rx, an R protein involved in plant immunity. Plant Cell 2007 1.51
4 Kinetic basis for the competitive recruitment of TolB by the intrinsically disordered translocation domain of colicin E9. J Mol Biol 2012 1.50
5 A force-activated trip switch triggers rapid dissociation of a colicin from its immunity protein. PLoS Biol 2013 1.48
6 Cell entry mechanism of enzymatic bacterial colicins: porin recruitment and the thermodynamics of receptor binding. Proc Natl Acad Sci U S A 2005 1.44
7 The Role of zinc in the disulphide stress-regulated anti-sigma factor RsrA from Streptomyces coelicolor. J Mol Biol 2003 1.42
8 The structural and energetic basis for high selectivity in a high-affinity protein-protein interaction. Proc Natl Acad Sci U S A 2010 1.34
9 Competitive recruitment of the periplasmic translocation portal TolB by a natively disordered domain of colicin E9. Proc Natl Acad Sci U S A 2006 1.24
10 Killing of E coli cells by E group nuclease colicins. Biochimie 2002 1.22
11 Directed epitope delivery across the Escherichia coli outer membrane through the porin OmpF. Proc Natl Acad Sci U S A 2010 1.21
12 Following evolutionary paths to protein-protein interactions with high affinity and selectivity. Nat Struct Mol Biol 2009 1.21
13 Highly discriminating protein-protein interaction specificities in the context of a conserved binding energy hotspot. J Mol Biol 2004 1.20
14 Thermodynamic consequences of bipartite immunity protein binding to the ribosomal ribonuclease colicin E3. Biochemistry 2003 1.20
15 Identification and structure of the anti-sigma factor-binding domain of the disulphide-stress regulated sigma factor sigma(R) from Streptomyces coelicolor. J Mol Biol 2002 1.19
16 Mutagenic scan of the H-N-H motif of colicin E9: implications for the mechanistic enzymology of colicins, homing enzymes and apoptotic endonucleases. Nucleic Acids Res 2002 1.18
17 Transcriptional profiling of colicin-induced cell death of Escherichia coli MG1655 identifies potential mechanisms by which bacteriocins promote bacterial diversity. J Bacteriol 2004 1.17
18 Self-association of TPR domains: Lessons learned from a designed, consensus-based TPR oligomer. Proteins 2010 1.17
19 Allosteric beta-propeller signalling in TolB and its manipulation by translocating colicins. EMBO J 2009 1.15
20 Molecular mimicry enables competitive recruitment by a natively disordered protein. J Am Chem Soc 2007 1.15
21 Structure-based analysis of the metal-dependent mechanism of H-N-H endonucleases. J Biol Chem 2004 1.14
22 Intrinsically disordered protein threads through the bacterial outer-membrane porin OmpF. Science 2013 1.13
23 The cytotoxic domain of colicin E9 is a channel-forming endonuclease. Nat Struct Biol 2002 1.10
24 Assignment of the zinc ligands in RsrA, a redox-sensing ZAS protein from Streptomyces coelicolor. Biochemistry 2006 1.05
25 Structural dynamics of the membrane translocation domain of colicin E9 and its interaction with TolB. J Mol Biol 2002 1.04
26 Nuclease colicins and their immunity proteins. Q Rev Biophys 2011 1.02
27 Flexibility in the receptor-binding domain of the enzymatic colicin E9 is required for toxicity against Escherichia coli cells. J Bacteriol 2004 1.01
28 Identification of the catalytic motif of the microbial ribosome inactivating cytotoxin colicin E3. Protein Sci 2004 1.01
29 Energy-dependent immunity protein release during tol-dependent nuclease colicin translocation. J Biol Chem 2009 0.99
30 Colicin E3 cleavage of 16S rRNA impairs decoding and accelerates tRNA translocation on Escherichia coli ribosomes. Mol Microbiol 2008 0.98
31 Structure of the ultra-high-affinity colicin E2 DNase--Im2 complex. J Mol Biol 2012 0.98
32 The role of electrostatics in colicin nuclease domain translocation into bacterial cells. J Biol Chem 2007 0.97
33 Probing metal ion binding and conformational properties of the colicin E9 endonuclease by electrospray ionization time-of-flight mass spectrometry. Protein Sci 2002 0.96
34 The kinetic basis for dual recognition in colicin endonuclease-immunity protein complexes. J Mol Biol 2005 0.95
35 Calorimetric dissection of colicin DNase--immunity protein complex specificity. Biochemistry 2006 0.94
36 TPR-Mediated self-association of plant SGT1. Biochemistry 2007 0.93
37 A kinetic analysis of regiospecific glucosylation by two glycosyltransferases of Arabidopsis thaliana: domain swapping to introduce new activities. J Biol Chem 2008 0.93
38 The effect of protein complexation on the mechanical stability of Im9. Biophys J 2007 0.92
39 Real-time monitoring of enzymatic DNA hydrolysis by electrospray ionization mass spectrometry. Nucleic Acids Res 2005 0.92
40 Experimental and computational analyses of the energetic basis for dual recognition of immunity proteins by colicin endonucleases. J Mol Biol 2008 0.92
41 Rapid detection of colicin E9-induced DNA damage using Escherichia coli cells carrying SOS promoter-lux fusions. J Bacteriol 2005 0.91
42 Blind prediction of interfacial water positions in CAPRI. Proteins 2013 0.90
43 OmpF enhances the ability of BtuB to protect susceptible Escherichia coli cells from colicin E9 cytotoxicity. FEBS Lett 2003 0.90
44 Clusters in an intrinsically disordered protein create a protein-binding site: the TolB-binding region of colicin E9. Biochemistry 2005 0.89
45 Conformational properties of the unfolded state of Im7 in nondenaturing conditions. J Mol Biol 2011 0.89
46 TolA modulates the oligomeric status of YbgF in the bacterial periplasm. J Mol Biol 2010 0.88
47 Global structural rearrangement of the cell penetrating ribonuclease colicin E3 on interaction with phospholipid membranes. Protein Sci 2006 0.88
48 Multistep binding of transition metals to the H-N-H endonuclease toxin colicin E9. Biochemistry 2002 0.88
49 Destabilization of the colicin E9 Endonuclease domain by interaction with negatively charged phospholipids: implications for colicin translocation into bacteria. J Biol Chem 2004 0.87
50 Structural aspects of the inhibition of DNase and rRNase colicins by their immunity proteins. Biochimie 2002 0.84
51 Characterisation of a mobile protein-binding epitope in the translocation domain of colicin E9. J Biomol NMR 2004 0.83
52 Biochemical characterization of RAR1 cysteine- and histidine-rich domains (CHORDs): a novel class of zinc-dependent protein-protein interaction modules. Biochemistry 2007 0.83
53 Colicins exploit native disorder to gain cell entry: a hitchhiker's guide to translocation. Biochem Soc Trans 2008 0.83
54 Colicin translocation across the Escherichia coli outer membrane. Biochem Soc Trans 2012 0.81
55 Distinct conformational stability and functional activity of four highly homologous endonuclease colicins. Protein Sci 2004 0.80
56 Structural dynamics of the receptor-binding domain of colicin E9. Faraday Discuss 2003 0.79
57 The role of an activating peptide in protease-mediated suicide of Escherichia coli K12. J Biol Chem 2004 0.78
58 Ligand-induced changes in the conformational dynamics of a bacterial cytotoxic endonuclease. Biochemistry 2004 0.78
59 Metal induced selectivity in phosphate ion binding in E9 DNase. Chem Commun (Camb) 2005 0.77
60 How bugs kill bugs: progress and challenges in bacteriocin research. Biochem Soc Trans 2012 0.76
61 Identification of essential residues within Lit, a cell death peptidase of Escherichia coli K-12. Biochemistry 2004 0.75
62 Immunity protein release from a cell-bound nuclease colicin complex requires global conformational rearrangement. Microbiologyopen 2013 0.75
63 Thermodynamic dissection of colicin interactions. Methods Enzymol 2011 0.75