Published in J Clin Psychopharmacol on August 01, 2004
Pharmacological evidence for a motivational role of kappa-opioid systems in ethanol dependence. Neuropsychopharmacology (2007) 2.61
Exposure to the taste of alcohol elicits activation of the mesocorticolimbic neurocircuitry. Neuropsychopharmacology (2007) 1.76
Pharmacotherapy of alcohol use disorders: seventy-five years of progress. J Stud Alcohol Drugs Suppl (2014) 1.14
Nalmefene: a new approach to the treatment of alcohol dependence. Subst Abuse Rehabil (2014) 1.10
Effects of opioid receptor gene variation on targeted nalmefene treatment in heavy drinkers. Alcohol Clin Exp Res (2008) 0.98
Medications development for the treatment of alcohol use disorder: insights into the predictive value of animal and human laboratory models. Addict Biol (2016) 0.80
A double-blind, placebo-controlled study of sertraline with naltrexone for alcohol dependence. Drug Alcohol Depend (2008) 0.79
Pharmacological means of reducing human drug dependence: a selective and narrative review of the clinical literature. Br J Clin Pharmacol (2014) 0.77
Weak evidence on nalmefene creates dilemmas for clinicians and poses questions for regulators and researchers. Addiction (2016) 0.76
Pharmacotherapy for alcohol use disorder: current and emerging therapies. Harv Rev Psychiatry (2015) 0.76
Targeted opioid receptor antagonists in the treatment of alcohol use disorders. CNS Drugs (2013) 0.76
Evaluation in alcohol use disorders - insights from the nalmefene experience. BMC Med (2016) 0.75
The opioid receptors as targets for drug abuse medication. Br J Pharmacol (2015) 0.75
Harms associated with taking nalmefene for substance use and impulse control disorders: A systematic review and meta-analysis of randomised controlled trials. PLoS One (2017) 0.75
Combined pharmacotherapies and behavioral interventions for alcohol dependence: the COMBINE study: a randomized controlled trial. JAMA (2006) 13.15
Topiramate for treating alcohol dependence: a randomized controlled trial. JAMA (2007) 6.81
An evaluation of mu-opioid receptor (OPRM1) as a predictor of naltrexone response in the treatment of alcohol dependence: results from the Combined Pharmacotherapies and Behavioral Interventions for Alcohol Dependence (COMBINE) study. Arch Gen Psychiatry (2008) 4.91
Efficacy and tolerability of long-acting injectable naltrexone for alcohol dependence: a randomized controlled trial. JAMA (2005) 4.64
A functional polymorphism of the mu-opioid receptor gene is associated with naltrexone response in alcohol-dependent patients. Neuropsychopharmacology (2003) 3.66
Alcohol treatment utilization: findings from the National Epidemiologic Survey on Alcohol and Related Conditions. Drug Alcohol Depend (2006) 3.40
Allelic and haplotypic association of GABRA2 with alcohol dependence. Am J Med Genet B Neuropsychiatr Genet (2004) 3.10
Opioid-, cannabis- and alcohol-dependent women show more rapid progression to substance abuse treatment. Drug Alcohol Depend (2004) 3.09
Diagnostic reliability of the Semi-structured Assessment for Drug Dependence and Alcoholism (SSADDA). Drug Alcohol Depend (2005) 3.09
Research to practice: adoption of naltrexone in alcoholism treatment. J Subst Abuse Treat (2003) 2.91
Percentage of subjects with no heavy drinking days: evaluation as an efficacy endpoint for alcohol clinical trials. Alcohol Clin Exp Res (2010) 2.89
Establishing the feasibility of performance measures for alcohol and other drugs. J Subst Abuse Treat (2002) 2.75
Effects of the 2011 duty hour reforms on interns and their patients: a prospective longitudinal cohort study. JAMA Intern Med (2013) 2.52
Multicenter investigation of the opioid antagonist nalmefene in the treatment of pathological gambling. Am J Psychiatry (2006) 2.50
A prospective cohort study investigating factors associated with depression during medical internship. Arch Gen Psychiatry (2010) 2.41
Impact of substance use disorders on recovery from episodes of depression in bipolar disorder patients: prospective data from the Systematic Treatment Enhancement Program for Bipolar Disorder (STEP-BD). Am J Psychiatry (2009) 2.39
Association between alcoholism and gamma-amino butyric acid alpha2 receptor subtype in a Russian population. Alcohol Clin Exp Res (2005) 2.35
Reliability of DSM-IV diagnostic criteria using the semi-structured assessment for drug dependence and alcoholism (SSADDA). Drug Alcohol Depend (2007) 2.26
Genomewide linkage scan for cocaine dependence and related traits: significant linkages for a cocaine-related trait and cocaine-induced paranoia. Am J Med Genet B Neuropsychiatr Genet (2005) 2.24
Topiramate treatment for heavy drinkers: moderation by a GRIK1 polymorphism. Am J Psychiatry (2014) 2.18
Interaction of FKBP5 with childhood adversity on risk for post-traumatic stress disorder. Neuropsychopharmacology (2010) 2.16
Genomewide linkage scan for opioid dependence and related traits. Am J Hum Genet (2006) 2.15
Practical population group assignment with selected informative markers: characteristics and properties of Bayesian clustering via STRUCTURE. Genet Epidemiol (2005) 2.09
Directly administered antiretroviral therapy in methadone clinics is associated with improved HIV treatment outcomes, compared with outcomes among concurrent comparison groups. Clin Infect Dis (2006) 2.08
Haplotypes at the OPRM1 locus are associated with susceptibility to substance dependence in European-Americans. Am J Med Genet B Neuropsychiatr Genet (2003) 2.07
Interactive effect of stressful life events and the serotonin transporter 5-HTTLPR genotype on posttraumatic stress disorder diagnosis in 2 independent populations. Arch Gen Psychiatry (2009) 1.97
Association of an Asn40Asp (A118G) polymorphism in the mu-opioid receptor gene with substance dependence: a meta-analysis. Drug Alcohol Depend (2006) 1.96
Haplotype spanning TTC12 and ANKK1, flanked by the DRD2 and NCAM1 loci, is strongly associated to nicotine dependence in two distinct American populations. Hum Mol Genet (2006) 1.94
Association between two mu-opioid receptor gene (OPRM1) haplotype blocks and drug or alcohol dependence. Hum Mol Genet (2006) 1.93
Contingency management for alcohol use reduction: a pilot study using a transdermal alcohol sensor. Drug Alcohol Depend (2011) 1.87
Sex differences in striatal dopamine release in healthy adults. Biol Psychiatry (2006) 1.87
Opioid receptor gene (OPRM1, OPRK1, and OPRD1) variants and response to naltrexone treatment for alcohol dependence: results from the VA Cooperative Study. Alcohol Clin Exp Res (2007) 1.86
Understanding US addiction physicians' low rate of naltrexone prescription. Drug Alcohol Depend (2003) 1.86
CHRM2 gene predisposes to alcohol dependence, drug dependence and affective disorders: results from an extended case-control structured association study. Hum Mol Genet (2005) 1.85
Psychometric properties of the short index of problems as a measure of recent alcohol-related problems. Alcohol Clin Exp Res (2003) 1.84
Alcohol and opioid dependence medications: prescription trends, overall and by physician specialty. Drug Alcohol Depend (2008) 1.84
Diplotype trend regression analysis of the ADH gene cluster and the ALDH2 gene: multiple significant associations with alcohol dependence. Am J Hum Genet (2006) 1.82
Meta-analysis of the association of a functional serotonin transporter promoter polymorphism with alcohol dependence. Am J Med Genet B Neuropsychiatr Genet (2005) 1.80
Rare nonsynonymous variants in alpha-4 nicotinic acetylcholine receptor gene protect against nicotine dependence. Biol Psychiatry (2011) 1.76
A pilot trial of topiramate for the treatment of cocaine dependence. Drug Alcohol Depend (2004) 1.75
Burden of general medical conditions among individuals with bipolar disorder. Bipolar Disord (2004) 1.74
Effects of gender and family history of alcohol dependence on a behavioral task of impulsivity in healthy subjects. J Stud Alcohol (2002) 1.69
The relationship between recent alcohol use and sexual behaviors: gender differences among sexually transmitted disease clinic patients. Alcohol Clin Exp Res (2008) 1.65
The relationship between cocaine craving, psychosocial treatment, and subsequent cocaine use. Am J Psychiatry (2003) 1.63
Comorbid psychiatric diagnoses and their association with cocaine-induced psychosis in cocaine-dependent subjects. Am J Addict (2007) 1.63
GABRA2 alleles moderate the subjective effects of alcohol, which are attenuated by finasteride. Neuropsychopharmacology (2005) 1.63
Variation in GABRA2 predicts drinking behavior in project MATCH subjects. Alcohol Clin Exp Res (2007) 1.62
Reduction of alcohol drinking in young adults by naltrexone: a double-blind, placebo-controlled, randomized clinical trial of efficacy and safety. J Clin Psychiatry (2015) 1.62
Quality of life as an outcome measure in alcoholism treatment research. J Stud Alcohol Suppl (2005) 1.59
ADH4 gene variation is associated with alcohol and drug dependence: results from family controlled and population-structured association studies. Pharmacogenet Genomics (2005) 1.58
Variation in nicotinic acetylcholine receptor genes is associated with multiple substance dependence phenotypes. Neuropsychopharmacology (2010) 1.58
Interactive effects of the serotonin transporter 5-HTTLPR polymorphism and stressful life events on college student drinking and drug use. Biol Psychiatry (2006) 1.57
The effects of extended-release naltrexone on holiday drinking in alcohol-dependent patients. J Subst Abuse Treat (2008) 1.56
Association of haplotypic variants in DRD2, ANKK1, TTC12 and NCAM1 to alcohol dependence in independent case control and family samples. Hum Mol Genet (2007) 1.55
Effects of topiramate on urge to drink and the subjective effects of alcohol: a preliminary laboratory study. Alcohol Clin Exp Res (2008) 1.51
Genome-wide association study of alcohol dependence implicates KIAA0040 on chromosome 1q. Neuropsychopharmacology (2011) 1.50
Sober living houses for alcohol and drug dependence: 18-month outcomes. J Subst Abuse Treat (2010) 1.49
Markers in the 5'-region of GABRG1 associate to alcohol dependence and are in linkage disequilibrium with markers in the adjacent GABRA2 gene. Neuropsychopharmacology (2007) 1.48
A double-blind, placebo-controlled trial assessing the efficacy of varenicline tartrate for alcohol dependence. J Addict Med (2013) 1.47
Serotonin transporter gene polymorphism (5-HTTLPR) and anxiety reactivity in daily life: a daily process approach to gene-environment interaction. Psychosom Med (2007) 1.47
ADH4 gene variation is associated with alcohol dependence and drug dependence in European Americans: results from HWD tests and case-control association studies. Neuropsychopharmacology (2006) 1.45
HIV/AIDS and homelessness, Part 2: treatment issues. AIDS Read (2005) 1.45
Genetics of alcohol dependence. Hum Genet (2009) 1.44
Cocaine withdrawal severity and urine toxicology results from treatment entry predict outcome in medication trials for cocaine dependence. Addict Behav (2002) 1.44
Physicians' opinions about medications to treat alcoholism. Addiction (2003) 1.43
Efficacy of extended-release naltrexone in alcohol-dependent patients who are abstinent before treatment. J Clin Psychopharmacol (2007) 1.42
What did we learn from our study on sober living houses and where do we go from here? J Psychoactive Drugs (2010) 1.41
Brain derived neurotrophic factor (BDNF) gene variants and Alzheimer's disease, affective disorders, posttraumatic stress disorder, schizophrenia, and substance dependence. Am J Med Genet B Neuropsychiatr Genet (2006) 1.41
Barriers to the use of medications to treat alcoholism. Am J Addict (2003) 1.36
Improvement of physical health and quality of life of alcohol-dependent individuals with topiramate treatment: US multisite randomized controlled trial. Arch Intern Med (2008) 1.34
Nicotine gum for pregnant smokers: a randomized controlled trial. Obstet Gynecol (2008) 1.34
The effect of olanzapine on craving and alcohol consumption. Neuropsychopharmacology (2006) 1.34
Measurement of admixture proportions and description of admixture structure in different U.S. populations. Hum Mutat (2009) 1.33
Genome-wide association study identifies new susceptibility loci for posttraumatic stress disorder. Biol Psychiatry (2013) 1.32
Association between the cortisol response to opioid blockade and the Asn40Asp polymorphism at the mu-opioid receptor locus (OPRM1). Am J Med Genet B Neuropsychiatr Genet (2003) 1.29
Origins, issues and options in the development of the combined behavioral intervention. J Stud Alcohol Suppl (2005) 1.27
Adverse childhood events as risk factors for substance dependence: partial mediation by mood and anxiety disorders. Addict Behav (2009) 1.27
A double-blind, randomized trial of sertraline for alcohol dependence: moderation by age of onset [corrected] and 5-hydroxytryptamine transporter-linked promoter region genotype. J Clin Psychopharmacol (2011) 1.25
CNR1 variation modulates risk for drug and alcohol dependence. Biol Psychiatry (2007) 1.25
Genetic moderators of naltrexone's effects on alcohol cue reactivity. Alcohol Clin Exp Res (2006) 1.24
Targeted versus daily naltrexone: secondary analysis of effects on average daily drinking. Alcohol Clin Exp Res (2006) 1.23
Genomewide linkage scan for nicotine dependence: identification of a chromosome 5 risk locus. Biol Psychiatry (2006) 1.23
Haplotypic variants in DRD2, ANKK1, TTC12, and NCAM1 are associated with comorbid alcohol and drug dependence. Alcohol Clin Exp Res (2008) 1.22
Adherence, drug use, and treatment failure in a methadone-clinic-based program of directly administered antiretroviral therapy. AIDS Patient Care STDS (2007) 1.20
A double-blind, placebo-controlled trial of amantadine, propranolol, and their combination for the treatment of cocaine dependence in patients with severe cocaine withdrawal symptoms. Drug Alcohol Depend (2006) 1.17
Mecamylamine modifies the pharmacokinetics and reinforcing effects of alcohol. Alcohol Clin Exp Res (2002) 1.16
General-medical conditions in older patients with serious mental illness. Am J Geriatr Psychiatry (2005) 1.16
A functional neuropeptide Y Leu7Pro polymorphism associated with alcohol dependence in a large population sample from the United States. Arch Gen Psychiatry (2002) 1.16
Association of amphetamine-induced striatal dopamine release and cortisol responses to psychological stress. Neuropsychopharmacology (2007) 1.16
Sustaining motivational interviewing: a meta-analysis of training studies. Addiction (2014) 1.16
Trazodone for sleep disturbance after alcohol detoxification: a double-blind, placebo-controlled trial. Alcohol Clin Exp Res (2008) 1.15
Characterization of a likelihood based method and effects of markers informativeness in evaluation of admixture and population group assignment. BMC Genet (2005) 1.15
Differences in delta- and mu-opioid receptor blockade measured by positron emission tomography in naltrexone-treated recently abstinent alcohol-dependent subjects. Neuropsychopharmacology (2007) 1.14
Multiple ADH genes modulate risk for drug dependence in both African- and European-Americans. Hum Mol Genet (2006) 1.14
A randomized clinical trial of naltrexone and behavioral therapy for problem drinking men who have sex with men. J Consult Clin Psychol (2012) 1.13
Sertraline treatment of co-occurring alcohol dependence and major depression. J Clin Psychopharmacol (2006) 1.12