Published in Immunol Rev on June 01, 2004
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Yeast zymosan, a stimulus for TLR2 and dectin-1, induces regulatory antigen-presenting cells and immunological tolerance. J Clin Invest (2006) 3.31
The Global HIV/AIDS Vaccine Enterprise: scientific strategic plan. PLoS Med (2005) 2.95
Expanding roles for CD4⁺ T cells in immunity to viruses. Nat Rev Immunol (2012) 2.94
Choreography of cell motility and interaction dynamics imaged by two-photon microscopy in lymphoid organs. Annu Rev Immunol (2008) 2.86
A subset of dendritic cells induces CD4+ T cells to produce IFN-gamma by an IL-12-independent but CD70-dependent mechanism in vivo. J Exp Med (2007) 2.82
Memory CD4+ T cells induce innate responses independently of pathogen. Nat Med (2010) 2.61
HIV Gag protein conjugated to a Toll-like receptor 7/8 agonist improves the magnitude and quality of Th1 and CD8+ T cell responses in nonhuman primates. Proc Natl Acad Sci U S A (2005) 2.61
Modulation of adaptive immunity with Toll-like receptors. Semin Immunol (2009) 2.56
Intensified and protective CD4+ T cell immunity in mice with anti-dendritic cell HIV gag fusion antibody vaccine. J Exp Med (2006) 2.53
Antigen targeting to dendritic cells elicits long-lived T cell help for antibody responses. J Exp Med (2006) 2.43
Toll-like receptor 2-dependent induction of vitamin A-metabolizing enzymes in dendritic cells promotes T regulatory responses and inhibits autoimmunity. Nat Med (2009) 2.30
Dendritic cell control of tolerogenic responses. Immunol Rev (2011) 2.13
DEC-205 receptor on dendritic cells mediates presentation of HIV gag protein to CD8+ T cells in a spectrum of human MHC I haplotypes. Proc Natl Acad Sci U S A (2007) 2.04
HIV-1 gp120 mannoses induce immunosuppressive responses from dendritic cells. PLoS Pathog (2007) 1.90
Toll-like receptor expression and responsiveness of distinct murine splenic and mucosal B-cell subsets. PLoS One (2007) 1.82
Transdermal influenza immunization with vaccine-coated microneedle arrays. PLoS One (2009) 1.78
Division of labor, plasticity, and crosstalk between dendritic cell subsets. Curr Opin Immunol (2007) 1.70
Cytolytic CD4 cells: Direct mediators in infectious disease and malignancy. Cell Immunol (2010) 1.69
Using 3 TLR ligands as a combination adjuvant induces qualitative changes in T cell responses needed for antiviral protection in mice. J Clin Invest (2010) 1.58
Human TLR1 deficiency is associated with impaired mycobacterial signaling and protection from leprosy reversal reaction. PLoS Negl Trop Dis (2008) 1.56
Retinoic acid-dependent regulation of immune responses by dendritic cells and macrophages. Semin Immunol (2008) 1.51
Stabilization of influenza vaccine enhances protection by microneedle delivery in the mouse skin. PLoS One (2009) 1.42
Toll-like receptors: lessons to learn from normal and malignant human B cells. Blood (2008) 1.42
Protective immunity against H5N1 influenza virus by a single dose vaccination with virus-like particles. Virology (2010) 1.39
Enhanced memory responses to seasonal H1N1 influenza vaccination of the skin with the use of vaccine-coated microneedles. J Infect Dis (2010) 1.36
Expression and distribution of Toll-like receptors in the brain during murine neurocysticercosis. J Neuroimmunol (2006) 1.24
From the Th1/Th2 paradigm towards a Toll-like receptor/T-helper bias. Antimicrob Agents Chemother (2005) 1.23
Mature dendritic cells pulsed with exosomes stimulate efficient cytotoxic T-lymphocyte responses and antitumour immunity. Immunology (2006) 1.16
Salmonella flagellins are potent adjuvants for intranasally administered whole inactivated influenza vaccine. Vaccine (2009) 1.14
A new synthetic TLR4 agonist, GLA, allows dendritic cells targeted with antigen to elicit Th1 T-cell immunity in vivo. Eur J Immunol (2011) 1.14
Association of human TLR1 and TLR6 deficiency with altered immune responses to BCG vaccination in South African infants. PLoS Pathog (2011) 1.13
Adenovirus type 5 induces vitamin A-metabolizing enzymes in dendritic cells and enhances priming of gut-homing CD8 T cells. Mucosal Immunol (2011) 1.05
Cationic liposomes containing mycobacterial lipids: a new powerful Th1 adjuvant system. Infect Immun (2005) 1.03
The stimulation of CD8+ T cells by dendritic cells pulsed with polyketal microparticles containing ion-paired protein antigen and poly(inosinic acid)-poly(cytidylic acid). Biomaterials (2008) 1.03
Local response to microneedle-based influenza immunization in the skin. MBio (2012) 1.03
Networking at the level of host immunity: immune cell interactions during persistent viral infections. Cell Host Microbe (2013) 1.03
TLR-activated dendritic cells enhance the response of aged naive CD4 T cells via an IL-6-dependent mechanism. J Immunol (2010) 1.00
Self-assembled peptide nanofibers raising durable antibody responses against a malaria epitope. Biomaterials (2012) 0.99
Original encounter with antigen determines antigen-presenting cell imprinting of the quality of the immune response in mice. PLoS One (2009) 0.98
Advances in the design and delivery of peptide subunit vaccines with a focus on toll-like receptor agonists. Expert Rev Vaccines (2010) 0.96
Multiple innate signaling pathways cooperate with CD40 to induce potent, CD70-dependent cellular immunity. Vaccine (2009) 0.96
Agonists of Toll-like receptors 3, 4, 7, and 9 are candidates for use as adjuvants in an outer membrane vaccine against Neisseria meningitidis serogroup B. Infect Immun (2007) 0.96
Major subsets of human dendritic cells are efficiently transduced by self-complementary adeno-associated virus vectors 1 and 2. J Virol (2007) 0.95
Differential effect of TLR2 and TLR4 on the immune response after immunization with a vaccine against Neisseria meningitidis or Bordetella pertussis. PLoS One (2010) 0.93
Differential involvement of Th1 and Th17 in pathogenic autoimmune processes triggered by different TLR ligands. J Immunol (2013) 0.93
Tuberculosis Infection: Insight from Immunogenomics. Drug Discov Today Dis Mech (2007) 0.92
Regulation of CD4 T-cell receptor diversity by vaccine adjuvants. Immunology (2010) 0.91
The PorB porin from commensal Neisseria lactamica induces Th1 and Th2 immune responses to ovalbumin in mice and is a potential immune adjuvant. Vaccine (2007) 0.91
Comparison of TNFα to lipopolysaccharide as an inflammagen to characterize the idiosyncratic hepatotoxicity potential of drugs: Trovafloxacin as an example. Int J Mol Sci (2010) 0.91
Neisseria meningitidis PorB, a Toll-like receptor 2 ligand, improves the capacity of Francisella tularensis lipopolysaccharide to protect mice against experimental tularemia. Clin Vaccine Immunol (2008) 0.89
Poly(anhydride) nanoparticles act as active Th1 adjuvants through Toll-like receptor exploitation. Clin Vaccine Immunol (2010) 0.88
TLR2-dependent activation of β-catenin pathway in dendritic cells induces regulatory responses and attenuates autoimmune inflammation. J Immunol (2014) 0.88
Infected dendritic cells are sufficient to mediate the adjuvant activity generated by Venezuelan equine encephalitis virus replicon particles. Vaccine (2012) 0.88
Potent induction of antibody-secreting B cells by human dermal-derived CD14+ dendritic cells triggered by dual TLR ligation. J Immunol (2012) 0.88
Strategies to use immune modulators in therapeutic vaccines against cancer. Semin Oncol (2012) 0.86
Toll-like receptor activation enhances cell-mediated immunity induced by an antibody vaccine targeting human dendritic cells. J Transl Med (2007) 0.86
TLR2 engagement on CD4(+) T cells enhances effector functions and protective responses to Mycobacterium tuberculosis. Eur J Immunol (2014) 0.86
Highly efficient transduction of human plasmacytoid dendritic cells without phenotypic and functional maturation. J Transl Med (2009) 0.85
Constitutive expression of TNF-related activation-induced cytokine (TRANCE)/receptor activating NF-κB ligand (RANK)-L by rat plasmacytoid dendritic cells. PLoS One (2012) 0.85
Translational Mini-Review Series on Vaccines for HIV: Harnessing innate immunity for HIV vaccine development. Clin Exp Immunol (2009) 0.85
Mucosal adjuvant properties of the Shigella invasin complex. Infect Immun (2006) 0.85
In vitro atrazine exposure affects the phenotypic and functional maturation of dendritic cells. Toxicol Appl Pharmacol (2007) 0.84
Profiles of carbohydrate ligands associated with adsorbed proteins on self-assembled monolayers of defined chemistries. J Biomed Mater Res A (2010) 0.84
The requirement of CD80, CD86, and ICAM-1 on the ability of adjuvant formulations to potentiate antibody responses to a Plasmodium falciparum blood-stage vaccine. Vaccine (2007) 0.83
Targeting TLR2 for vaccine development. J Immunol Res (2014) 0.83
Critical role of TLR7 signaling in the priming of cross-protective cytotoxic T lymphocyte responses by a whole inactivated influenza virus vaccine. PLoS One (2013) 0.82
Acute inflammation induces immunomodulatory effects on myeloid cells associated with anti-tumor responses in a tumor mouse model. J Adv Res (2015) 0.82
Systems biology in vaccine design. Microb Biotechnol (2011) 0.82
Reprogramming of B cells into regulatory cells with engineered fusokines. Infect Disord Drug Targets (2012) 0.81
Mucosal adjuvants for influenza virus-like particle vaccine. Viral Immunol (2013) 0.81
CD4(+) T Cell Priming as Biomarker to Study Immune Response to Preventive Vaccines. Front Immunol (2013) 0.81
Dendritic cell vaccination with a toll-like receptor agonist derived from mycobacteria enhances anti-tumor immunity. Oncotarget (2015) 0.81
A push-pull vaccine strategy using Toll-like receptor ligands, IL-15, and blockade of negative regulation to improve the quality and quantity of T cell immune responses. Vaccine (2011) 0.80
Surface plasmon resonance measurements of plasma antibody avidity during primary and secondary responses to anthrax protective antigen. J Immunol Methods (2013) 0.79
Mucosal adjuvanticity of a Shigella invasin complex with dna-based vaccines. Clin Vaccine Immunol (2009) 0.79
Antiviral activity of ginseng extract against respiratory syncytial virus infection. Int J Mol Med (2014) 0.79
Covalent modification of cell surfaces with TLR agonists improves & directs immune stimulation. Chem Commun (Camb) (2013) 0.78
Innate responses induced by whole inactivated virus or subunit influenza vaccines in cultured dendritic cells correlate with immune responses in vivo. PLoS One (2015) 0.77
T Cell Vaccinology: Beyond the Reflection of Infectious Responses. Trends Immunol (2016) 0.77
Manipulation of EAT-2 expression promotes induction of multiple beneficial regulatory and effector functions of the human innate immune system as a novel immunomodulatory strategy. Int Immunol (2013) 0.77
Induction of innate immune signatures following polyepitope protein-glycoprotein B-TLR4&9 agonist immunization generates multifunctional CMV-specific cellular and humoral immunity. Hum Vaccin Immunother (2014) 0.76
Modulation of Innate Immune Responses via Covalently Linked TLR Agonists. ACS Cent Sci (2015) 0.76
Different expressions of TLRs and related factors in peripheral blood of preterm infants. Int J Clin Exp Med (2015) 0.75
HIV vaccine trial exploits a dual and central role for innate immunity. J Virol (2014) 0.75
Generation of T cell responses targeting the reactive metabolite of halothane in mice. Toxicol Lett (2010) 0.75
Combination of TLR1/2 and TLR3 ligands enhances CD4(+) T cell longevity and antibody responses by modulating type I IFN production. Sci Rep (2016) 0.75
Sterile inflammation induced by Carbopol elicits robust adaptive immune responses in the absence of pathogen-associated molecular patterns. Vaccine (2016) 0.75
Chemical cross-linking of HIV-1 Env for direct TLR7/8 ligand conjugation compromises recognition of conserved antigenic determinants. Virology (2013) 0.75
Co-delivery of Dual Toll-Like Receptor Agonists and Antigen in Poly(Lactic-Co-Glycolic) Acid/Polyethylenimine Cationic Hybrid Nanoparticles Promote Efficient In Vivo Immune Responses. Front Immunol (2017) 0.75
CD8(+) memory T-cell inflation renders compromised CD4(+) T-cell-dependent CD8(+) T-cell immunity via naïve T-cell anergy. Immunotargets Ther (2017) 0.75
Hepatitis C virus infection--pathobiology and implications for new therapeutic options. Dig Dis Sci (2007) 0.75