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1
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Genome-wide association study identifies novel breast cancer susceptibility loci.
|
Nature
|
2007
|
29.23
|
|
2
|
Large-scale genotyping identifies 41 new loci associated with breast cancer risk.
|
Nat Genet
|
2013
|
8.24
|
|
3
|
A common coding variant in CASP8 is associated with breast cancer risk.
|
Nat Genet
|
2007
|
7.35
|
|
4
|
Newly discovered breast cancer susceptibility loci on 3p24 and 17q23.2.
|
Nat Genet
|
2009
|
7.30
|
|
5
|
Heterogeneity of breast cancer associations with five susceptibility loci by clinical and pathological characteristics.
|
PLoS Genet
|
2008
|
6.22
|
|
6
|
Associations of breast cancer risk factors with tumor subtypes: a pooled analysis from the Breast Cancer Association Consortium studies.
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J Natl Cancer Inst
|
2010
|
4.54
|
|
7
|
Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer.
|
Nat Genet
|
2013
|
4.35
|
|
8
|
Genome-wide association studies identify four ER negative-specific breast cancer risk loci.
|
Nat Genet
|
2013
|
3.81
|
|
9
|
Common breast cancer-predisposition alleles are associated with breast cancer risk in BRCA1 and BRCA2 mutation carriers.
|
Am J Hum Genet
|
2008
|
3.41
|
|
10
|
Genome-wide association analysis identifies three new breast cancer susceptibility loci.
|
Nat Genet
|
2012
|
3.20
|
|
11
|
Low penetrance breast cancer susceptibility loci are associated with specific breast tumor subtypes: findings from the Breast Cancer Association Consortium.
|
Hum Mol Genet
|
2011
|
2.72
|
|
12
|
Agreement between self-reported breast cancer treatment and medical records in a population-based Breast Cancer Family Registry.
|
J Clin Oncol
|
2005
|
2.70
|
|
13
|
An international initiative to identify genetic modifiers of cancer risk in BRCA1 and BRCA2 mutation carriers: the Consortium of Investigators of Modifiers of BRCA1 and BRCA2 (CIMBA).
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Breast Cancer Res
|
2007
|
2.46
|
|
14
|
Functional variants at the 11q13 risk locus for breast cancer regulate cyclin D1 expression through long-range enhancers.
|
Am J Hum Genet
|
2013
|
2.24
|
|
15
|
Obesity and outcomes in premenopausal and postmenopausal breast cancer.
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Cancer Epidemiol Biomarkers Prev
|
2005
|
2.14
|
|
16
|
Incidence of total knee and hip replacement for osteoarthritis in relation to circulating sex steroid hormone concentrations in women.
|
Arthritis Rheumatol
|
2014
|
2.05
|
|
17
|
Identification of a BRCA2-specific modifier locus at 6p24 related to breast cancer risk.
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PLoS Genet
|
2013
|
1.88
|
|
18
|
19p13.1 is a triple-negative-specific breast cancer susceptibility locus.
|
Cancer Res
|
2012
|
1.81
|
|
19
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Breast cancer prognosis in BRCA1 and BRCA2 mutation carriers: an International Prospective Breast Cancer Family Registry population-based cohort study.
|
J Clin Oncol
|
2011
|
1.78
|
|
20
|
Is benign rolandic epilepsy genetically determined?
|
Ann Neurol
|
2004
|
1.68
|
|
21
|
Association of ESR1 gene tagging SNPs with breast cancer risk.
|
Hum Mol Genet
|
2009
|
1.58
|
|
22
|
The breast cancer susceptibility mutation PALB2 1592delT is associated with an aggressive tumor phenotype.
|
Clin Cancer Res
|
2009
|
1.58
|
|
23
|
Associations of common variants at 1p11.2 and 14q24.1 (RAD51L1) with breast cancer risk and heterogeneity by tumor subtype: findings from the Breast Cancer Association Consortium.
|
Hum Mol Genet
|
2011
|
1.56
|
|
24
|
Evidence of gene-environment interactions between common breast cancer susceptibility loci and established environmental risk factors.
|
PLoS Genet
|
2013
|
1.56
|
|
25
|
Fine-scale mapping of the FGFR2 breast cancer risk locus: putative functional variants differentially bind FOXA1 and E2F1.
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Am J Hum Genet
|
2013
|
1.39
|
|
26
|
Tamoxifen and risk of contralateral breast cancer for BRCA1 and BRCA2 mutation carriers.
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J Clin Oncol
|
2013
|
1.29
|
|
27
|
Five polymorphisms and breast cancer risk: results from the Breast Cancer Association Consortium.
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Cancer Epidemiol Biomarkers Prev
|
2009
|
1.29
|
|
28
|
11q13 is a susceptibility locus for hormone receptor positive breast cancer.
|
Hum Mutat
|
2012
|
1.26
|
|
29
|
The role of genetic breast cancer susceptibility variants as prognostic factors.
|
Hum Mol Genet
|
2012
|
1.23
|
|
30
|
Prognosis of premenopausal breast cancer and childbirth prior to diagnosis.
|
J Clin Oncol
|
2004
|
1.20
|
|
31
|
IL2RA/CD25 polymorphisms contribute to multiple sclerosis susceptibility.
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J Neurol
|
2007
|
1.18
|
|
32
|
Association between a germline OCA2 polymorphism at chromosome 15q13.1 and estrogen receptor-negative breast cancer survival.
|
J Natl Cancer Inst
|
2010
|
1.17
|
|
33
|
Medical radiation exposure and breast cancer risk: findings from the Breast Cancer Family Registry.
|
Int J Cancer
|
2007
|
1.17
|
|
34
|
Psychosocial factors and survival of young women with breast cancer: a population-based prospective cohort study.
|
J Clin Oncol
|
2008
|
1.17
|
|
35
|
Past recreational physical activity, body size, and all-cause mortality following breast cancer diagnosis: results from the Breast Cancer Family Registry.
|
Breast Cancer Res Treat
|
2010
|
1.14
|
|
36
|
Comparison of 6q25 breast cancer hits from Asian and European Genome Wide Association Studies in the Breast Cancer Association Consortium (BCAC).
|
PLoS One
|
2012
|
1.13
|
|
37
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Evaluating HapMap SNP data transferability in a large-scale genotyping project involving 175 cancer-associated genes.
|
Hum Genet
|
2005
|
1.13
|
|
38
|
A role for XRCC2 gene polymorphisms in breast cancer risk and survival.
|
J Med Genet
|
2011
|
1.10
|
|
39
|
BRCA1 and BRCA2 mutation carriers, oral contraceptive use, and breast cancer before age 50.
|
Cancer Epidemiol Biomarkers Prev
|
2006
|
1.07
|
|
40
|
Pancreatic cancer risk and levels of trace elements.
|
Gut
|
2011
|
1.06
|
|
41
|
Genetic analysis of the vitamin D receptor gene in two epithelial cancers: melanoma and breast cancer case-control studies.
|
BMC Cancer
|
2008
|
1.06
|
|
42
|
Immunohistochemical expression of DNA repair proteins in familial breast cancer differentiate BRCA2-associated tumors.
|
J Clin Oncol
|
2005
|
1.05
|
|
43
|
Pigmentation-related genes and their implication in malignant melanoma susceptibility.
|
Exp Dermatol
|
2009
|
1.02
|
|
44
|
Association study of 69 genes in the ret pathway identifies low-penetrance loci in sporadic medullary thyroid carcinoma.
|
Cancer Res
|
2007
|
1.01
|
|
45
|
Prediagnosis reproductive factors and all-cause mortality for women with breast cancer in the breast cancer family registry.
|
Cancer Epidemiol Biomarkers Prev
|
2009
|
1.00
|
|
46
|
Mammographic densities during the menopausal transition: a longitudinal study of Australian-born women.
|
Menopause
|
2007
|
0.99
|
|
47
|
Refined histopathological predictors of BRCA1 and BRCA2 mutation status: a large-scale analysis of breast cancer characteristics from the BCAC, CIMBA, and ENIGMA consortia.
|
Breast Cancer Res
|
2014
|
0.99
|
|
48
|
Immunohistochemical classification of non-BRCA1/2 tumors identifies different groups that demonstrate the heterogeneity of BRCAX families.
|
Mod Pathol
|
2007
|
0.98
|
|
49
|
Are we overestimating the penetrance of mutations in SDHB?
|
Hum Mutat
|
2010
|
0.97
|
|
50
|
9q31.2-rs865686 as a susceptibility locus for estrogen receptor-positive breast cancer: evidence from the Breast Cancer Association Consortium.
|
Cancer Epidemiol Biomarkers Prev
|
2012
|
0.95
|
|
51
|
No increased risk of breast cancer associated with alcohol consumption among carriers of BRCA1 and BRCA2 mutations ages <50 years.
|
Cancer Epidemiol Biomarkers Prev
|
2006
|
0.93
|
|
52
|
Analyzing the etiology of benign rolandic epilepsy: a multicenter twin collaboration.
|
Epilepsia
|
2006
|
0.93
|
|
53
|
Risk of pancreatic cancer in breast cancer families from the breast cancer family registry.
|
Cancer Epidemiol Biomarkers Prev
|
2013
|
0.91
|
|
54
|
Missense variants in ATM in 26,101 breast cancer cases and 29,842 controls.
|
Cancer Epidemiol Biomarkers Prev
|
2010
|
0.91
|
|
55
|
The high producer variant of the Fc-receptor like-3 (FCRL3) gene is involved in protection against multiple sclerosis.
|
J Neuroimmunol
|
2008
|
0.91
|
|
56
|
Investigation of gene-environment interactions between 47 newly identified breast cancer susceptibility loci and environmental risk factors.
|
Int J Cancer
|
2014
|
0.90
|
|
57
|
BRCA2 Polymorphic Stop Codon K3326X and the Risk of Breast, Prostate, and Ovarian Cancers.
|
J Natl Cancer Inst
|
2015
|
0.90
|
|
58
|
Contralateral risk-reducing mastectomy in BRCA1 and BRCA2 mutation carriers and other high-risk women in the Kathleen Cuningham Foundation Consortium for Research into Familial Breast Cancer (kConFab).
|
Breast Cancer Res Treat
|
2009
|
0.88
|
|
59
|
Family history of breast cancer and all-cause mortality after breast cancer diagnosis in the Breast Cancer Family Registry.
|
Breast Cancer Res Treat
|
2008
|
0.88
|
|
60
|
An inverse association between ovarian cysts and breast cancer in the breast cancer family registry.
|
Int J Cancer
|
2006
|
0.88
|
|
61
|
The HER2 I655V polymorphism and risk of breast cancer in women < age 40 years.
|
Cancer Epidemiol Biomarkers Prev
|
2003
|
0.88
|
|
62
|
A 7 Mb region within 11q13 may contain a high penetrance gene for breast cancer.
|
Breast Cancer Res Treat
|
2009
|
0.88
|
|
63
|
Preventing breast and ovarian cancers in high-risk BRCA1 and BRCA2 mutation carriers.
|
Med J Aust
|
2013
|
0.87
|
|
64
|
Do BRCA1 and BRCA2 mutation carriers have earlier natural menopause than their noncarrier relatives? Results from the Kathleen Cuningham Foundation Consortium for Research into Familial Breast Cancer.
|
J Clin Oncol
|
2013
|
0.87
|
|
65
|
Identification of new genetic susceptibility loci for breast cancer through consideration of gene-environment interactions.
|
Genet Epidemiol
|
2013
|
0.86
|
|
66
|
A twin study of genetic influences on epilepsy outcome.
|
Twin Res
|
2003
|
0.85
|
|
67
|
Risk factors for uncommon histologic subtypes of breast cancer using centralized pathology review in the Breast Cancer Family Registry.
|
Breast Cancer Res Treat
|
2012
|
0.84
|
|
68
|
Haplotype patterns in cancer-related genes with long-range linkage disequilibrium: no evidence of association with breast cancer or positive selection.
|
Eur J Hum Genet
|
2007
|
0.83
|
|
69
|
Succinate dehydrogenase D variants do not constitute a risk factor for developing C cell hyperplasia or sporadic medullary thyroid carcinoma.
|
J Clin Endocrinol Metab
|
2004
|
0.82
|
|
70
|
Evaluating new candidate SNPs as low penetrance risk factors in sporadic breast cancer: a two-stage Spanish case-control study.
|
Gynecol Oncol
|
2008
|
0.82
|
|
71
|
Diagnostic chest X-rays and breast cancer risk before age 50 years for BRCA1 and BRCA2 mutation carriers.
|
Cancer Epidemiol Biomarkers Prev
|
2013
|
0.81
|
|
72
|
Bone Morphogenetic Proteins in Spinal Surgery: What Is the Fusion Rate and Do They Cause Cancer?
|
Spine (Phila Pa 1976)
|
2015
|
0.81
|
|
73
|
A protein-truncating mutation in CYP17A1 in three sisters with early-onset breast cancer.
|
Hum Mutat
|
2005
|
0.81
|
|
74
|
Breast cancer risk and 6q22.33: combined results from Breast Cancer Association Consortium and Consortium of Investigators on Modifiers of BRCA1/2.
|
PLoS One
|
2012
|
0.80
|
|
75
|
Polymorphisms in TRAIL receptor genes and risk of breast cancer in Spanish women.
|
Cancer Biomark
|
2007
|
0.80
|
|
76
|
CYP17 genetic polymorphism, breast cancer, and breast cancer risk factors: Australian Breast Cancer Family Study.
|
Breast Cancer Res
|
2005
|
0.79
|
|
77
|
Socio-economic status and survival from breast cancer for young, Australian, urban women.
|
Aust N Z J Public Health
|
2010
|
0.75
|
|
78
|
The 'Pokemon' (ZBTB7) Gene: No Evidence of Association with Sporadic Breast Cancer.
|
Clin Med Oncol
|
2008
|
0.75
|
|
79
|
Reply: To PMID 24692288.
|
Arthritis Rheumatol
|
2015
|
0.75
|
|
80
|
Association of DNA Methylation-Based Biological Age with Health Risk Factors, and Overall and Cause-Specific Mortality.
|
Am J Epidemiol
|
2017
|
0.75
|
|
81
|
Blood pressure and risk of breast cancer, overall and by subtypes: a prospective cohort study.
|
J Hypertens
|
2017
|
0.75
|
|
82
|
Reply.
|
J Hypertens
|
2017
|
0.75
|
|
83
|
Testing for Gene-Environment Interactions Using a Prospective Family Cohort Design: Body Mass Index in Early and Later Adulthood and Risk of Breast Cancer.
|
Am J Epidemiol
|
2017
|
0.75
|
|
84
|
Human beta-defensins (HBD1 and HBD3) and malignant melanoma susceptibility.
|
Melanoma Res
|
2009
|
0.75
|
|
85
|
Obstetric events as a risk factor for febrile seizures: a community-based twin study.
|
Twin Res Hum Genet
|
2008
|
0.75
|