| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
Increased endoplasmic reticulum stress in atherosclerotic plaques associated with acute coronary syndrome.
|
Circulation
|
2007
|
3.77
|
|
2
|
Prolonged endoplasmic reticulum stress in hypertrophic and failing heart after aortic constriction: possible contribution of endoplasmic reticulum stress to cardiac myocyte apoptosis.
|
Circulation
|
2004
|
3.16
|
|
3
|
Human atrial natriuretic peptide and nicorandil as adjuncts to reperfusion treatment for acute myocardial infarction (J-WIND): two randomised trials.
|
Lancet
|
2007
|
2.48
|
|
4
|
Overexpression of endoplasmic reticulum-resident chaperone attenuates cardiomyocyte death induced by proteasome inhibition.
|
Cardiovasc Res
|
2008
|
2.05
|
|
5
|
Metformin prevents progression of heart failure in dogs: role of AMP-activated protein kinase.
|
Circulation
|
2009
|
1.95
|
|
6
|
Activation of adenosine A1 receptor attenuates cardiac hypertrophy and prevents heart failure in murine left ventricular pressure-overload model.
|
Circ Res
|
2003
|
1.82
|
|
7
|
Erythropoietin enhances neovascularization of ischemic myocardium and improves left ventricular dysfunction after myocardial infarction in dogs.
|
J Am Coll Cardiol
|
2006
|
1.74
|
|
8
|
AMPK controls the speed of microtubule polymerization and directional cell migration through CLIP-170 phosphorylation.
|
Nat Cell Biol
|
2010
|
1.72
|
|
9
|
Prolonged targeting of ischemic/reperfused myocardium by liposomal adenosine augments cardioprotection in rats.
|
J Am Coll Cardiol
|
2009
|
1.71
|
|
10
|
Natriuretic peptides enhance the production of adiponectin in human adipocytes and in patients with chronic heart failure.
|
J Am Coll Cardiol
|
2009
|
1.63
|
|
11
|
Ablation of C/EBP homologous protein attenuates endoplasmic reticulum-mediated apoptosis and cardiac dysfunction induced by pressure overload.
|
Circulation
|
2010
|
1.63
|
|
12
|
A cardiac myosin light chain kinase regulates sarcomere assembly in the vertebrate heart.
|
J Clin Invest
|
2007
|
1.61
|
|
13
|
Erythropoietin just before reperfusion reduces both lethal arrhythmias and infarct size via the phosphatidylinositol-3 kinase-dependent pathway in canine hearts.
|
Cardiovasc Drugs Ther
|
2005
|
1.59
|
|
14
|
Aldosterone nongenomically worsens ischemia via protein kinase C-dependent pathways in hypoperfused canine hearts.
|
Hypertension
|
2005
|
1.53
|
|
15
|
Depression of proteasome activities during the progression of cardiac dysfunction in pressure-overloaded heart of mice.
|
Biochem Biophys Res Commun
|
2005
|
1.33
|
|
16
|
Long-term stimulation of adenosine A2b receptors begun after myocardial infarction prevents cardiac remodeling in rats.
|
Circulation
|
2006
|
1.21
|
|
17
|
PKA rapidly enhances proteasome assembly and activity in in vivo canine hearts.
|
J Mol Cell Cardiol
|
2008
|
1.20
|
|
18
|
Evaluation of intramitochondrial ATP levels identifies G0/G1 switch gene 2 as a positive regulator of oxidative phosphorylation.
|
Proc Natl Acad Sci U S A
|
2013
|
1.02
|
|
19
|
Identification of genes related to heart failure using global gene expression profiling of human failing myocardium.
|
Biochem Biophys Res Commun
|
2010
|
1.01
|
|
20
|
Protein kinase A as another mediator of ischemic preconditioning independent of protein kinase C.
|
Circulation
|
2004
|
1.01
|
|
21
|
Inhibition of cardiac remodeling by pravastatin is associated with amelioration of endoplasmic reticulum stress.
|
Hypertens Res
|
2008
|
1.01
|
|
22
|
Celiprolol, a vasodilatory beta-blocker, inhibits pressure overload-induced cardiac hypertrophy and prevents the transition to heart failure via nitric oxide-dependent mechanisms in mice.
|
Circulation
|
2004
|
1.00
|
|
23
|
Long-acting Ca2+ blockers prevent myocardial remodeling induced by chronic NO inhibition in rats.
|
Hypertension
|
2003
|
0.99
|
|
24
|
Prolonged transient acidosis during early reperfusion contributes to the cardioprotective effects of postconditioning.
|
Am J Physiol Heart Circ Physiol
|
2007
|
0.97
|
|
25
|
Lamr1 functional retroposon causes right ventricular dysplasia in mice.
|
Nat Genet
|
2004
|
0.95
|
|
26
|
Raloxifene prevents cardiac hypertrophy and dysfunction in pressure-overloaded mice.
|
Hypertension
|
2003
|
0.95
|
|
27
|
Identification of a novel substrate for TNFalpha-induced kinase NUAK2.
|
Biochem Biophys Res Commun
|
2007
|
0.95
|
|
28
|
Functional alterations of cardiac proteasomes under physiological and pathological conditions.
|
Cardiovasc Res
|
2009
|
0.94
|
|
29
|
Control of plasma glucose with alpha-glucosidase inhibitor attenuates oxidative stress and slows the progression of heart failure in mice.
|
Cardiovasc Res
|
2006
|
0.92
|
|
30
|
Optimal windows of statin use for immediate infarct limitation: 5'-nucleotidase as another downstream molecule of phosphatidylinositol 3-kinase.
|
Circulation
|
2004
|
0.90
|
|
31
|
X-box binding protein 1 regulates brain natriuretic peptide through a novel AP1/CRE-like element in cardiomyocytes.
|
J Mol Cell Cardiol
|
2010
|
0.90
|
|
32
|
Granulocyte colony-stimulating factor mediates cardioprotection against ischemia/reperfusion injury via phosphatidylinositol-3-kinase/Akt pathway in canine hearts.
|
Cardiovasc Drugs Ther
|
2006
|
0.88
|
|
33
|
A role of opening of mitochondrial ATP-sensitive potassium channels in the infarct size-limiting effect of ischemic preconditioning via activation of protein kinase C in the canine heart.
|
Biochem Biophys Res Commun
|
2005
|
0.88
|
|
34
|
Protecting endothelial function: A novel therapeutic target of ATP-sensitive potassium channel openers.
|
Cardiovasc Res
|
2006
|
0.88
|
|
35
|
Atorvastatin slows the progression of cardiac remodeling in mice with pressure overload and inhibits epidermal growth factor receptor activation.
|
Hypertens Res
|
2008
|
0.87
|
|
36
|
Angiotensin II type 1 receptor blocker prevents atrial structural remodeling in rats with hypertension induced by chronic nitric oxide inhibition.
|
Hypertens Res
|
2006
|
0.87
|
|
37
|
S-nitrosylated and pegylated hemoglobin, a newly developed artificial oxygen carrier, exerts cardioprotection against ischemic hearts.
|
J Mol Cell Cardiol
|
2007
|
0.87
|
|
38
|
Development of anti-HB-EGF immunoliposomes for the treatment of breast cancer.
|
J Control Release
|
2011
|
0.86
|
|
39
|
Dipeptidyl-peptidase IV inhibition improves pathophysiology of heart failure and increases survival rate in pressure-overloaded mice.
|
Am J Physiol Heart Circ Physiol
|
2013
|
0.86
|
|
40
|
A histamine H₂ receptor blocker ameliorates development of heart failure in dogs independently of β-adrenergic receptor blockade.
|
Basic Res Cardiol
|
2010
|
0.86
|
|
41
|
Benidipine, a long-acting calcium channel blocker, inhibits cardiac remodeling in pressure-overloaded mice.
|
Cardiovasc Res
|
2005
|
0.85
|
|
42
|
Liposomal amiodarone augments anti-arrhythmic effects and reduces hemodynamic adverse effects in an ischemia/reperfusion rat model.
|
Cardiovasc Drugs Ther
|
2013
|
0.84
|
|
43
|
Amlodipine ameliorates myocardial hypertrophy by inhibiting EGFR phosphorylation.
|
Biochem Biophys Res Commun
|
2005
|
0.84
|
|
44
|
Treatment of cerebral ischemia-reperfusion injury with PEGylated liposomes encapsulating FK506.
|
FASEB J
|
2012
|
0.83
|
|
45
|
H(2) mediates cardioprotection via involvements of K(ATP) channels and permeability transition pores of mitochondria in dogs.
|
Cardiovasc Drugs Ther
|
2012
|
0.82
|
|
46
|
[Role of endoplasmic reticulum stress in hypertrophic and failing hearts].
|
Nihon Yakurigaku Zasshi
|
2005
|
0.82
|
|
47
|
Blockade of histamine H2 receptors protects the heart against ischemia and reperfusion injury in dogs.
|
J Mol Cell Cardiol
|
2006
|
0.82
|
|
48
|
Impaired glucose tolerance: a possible contributor to left ventricular hypertrophy and diastolic dysfunction.
|
Int J Cardiol
|
2006
|
0.82
|
|
49
|
A single injection of liposomal asialo-erythropoietin improves motor function deficit caused by cerebral ischemia/reperfusion.
|
Int J Pharm
|
2012
|
0.81
|
|
50
|
Eicosapentaenoic acid reduces myocardial injury induced by ischemia and reperfusion in rabbit hearts.
|
J Cardiovasc Pharmacol
|
2003
|
0.81
|
|
51
|
Beta-adrenoceptor blocker carvedilol provides cardioprotection via an adenosine-dependent mechanism in ischemic canine hearts.
|
Circulation
|
2004
|
0.81
|
|
52
|
Opening of the adenosine triphosphate-sensitive potassium channel attenuates cardiac remodeling induced by long-term inhibition of nitric oxide synthesis: role of 70-kDa S6 kinase and extracellular signal-regulated kinase.
|
J Am Coll Cardiol
|
2002
|
0.81
|
|
53
|
Isoform-specific intermolecular disulfide bond formation of heterochromatin protein 1 (HP1).
|
J Biol Chem
|
2010
|
0.80
|
|
54
|
The antagonism of aldosterone receptor prevents the development of hypertensive heart failure induced by chronic inhibition of nitric oxide synthesis in rats.
|
Cardiovasc Drugs Ther
|
2006
|
0.80
|
|
55
|
Canine DNA array as a potential tool for combining physiology and molecular biology.
|
Circ J
|
2003
|
0.80
|
|
56
|
Identification of p32 as a novel substrate for ATM in heart.
|
Biochem Biophys Res Commun
|
2007
|
0.80
|
|
57
|
Raloxifene improves coronary perfusion, cardiac contractility, and myocardial metabolism in the ischemic heart: role of phosphatidylinositol 3-kinase/Akt pathway.
|
J Cardiovasc Pharmacol
|
2004
|
0.79
|
|
58
|
Methotrexate and MX-68, a new derivative of methotrexate, limit infarct size via adenosine-dependent mechanisms in canine hearts.
|
J Cardiovasc Pharmacol
|
2004
|
0.79
|
|
59
|
Selective blockade of serotonin 5-HT2A receptor increases coronary blood flow via augmented cardiac nitric oxide release through 5-HT1B receptor in hypoperfused canine hearts.
|
J Mol Cell Cardiol
|
2004
|
0.78
|
|
60
|
Ablation of MEK kinase 1 suppresses intimal hyperplasia by impairing smooth muscle cell migration and urokinase plasminogen activator expression in a mouse blood-flow cessation model.
|
Circulation
|
2005
|
0.78
|
|
61
|
Amelioration of cerebral ischemia-reperfusion injury based on liposomal drug delivery system with asialo-erythropoietin.
|
J Control Release
|
2012
|
0.78
|
|
62
|
Derivation of a mathematical expression for predicting the time to cardiac events in patients with heart failure: a retrospective clinical study.
|
Hypertens Res
|
2012
|
0.78
|
|
63
|
Rationale and design of a large-scale trial using atrial natriuretic peptide (ANP) as an adjunct to percutaneous coronary intervention for ST-segment elevation acute myocardial infarction: Japan-Working groups of acute myocardial infarction for the reduction of Necrotic Damage by ANP (J-WIND-ANP).
|
Circ J
|
2004
|
0.77
|
|
64
|
Celiprolol increases coronary blood flow and reduces severity of myocardial ischemia via nitric oxide release.
|
J Cardiovasc Pharmacol
|
2003
|
0.76
|
|
65
|
A calcium channel blocker activates both ecto-5(')-nucleotidase and NO synthase in HUVEC.
|
Biochem Biophys Res Commun
|
2003
|
0.76
|
|
66
|
New therapeutic application of erythropoietin against ischemic heart diseases.
|
J Pharmacol Sci
|
2006
|
0.75
|
|
67
|
Noninvasive and quantitative live imaging reveals a potential stress-responsive enhancer in the failing heart.
|
FASEB J
|
2014
|
0.75
|
|
68
|
Erythropoietin, progenitor cells and restenosis. A critique of Stein et al.
|
Thromb Haemost
|
2012
|
0.75
|
|
69
|
Blockade of angiotensin II receptors reduces the expression of receptors for advanced glycation end products in human endothelial cells.
|
Arterioscler Thromb Vasc Biol
|
2006
|
0.75
|
|
70
|
[Opening of ATP-sensitive potassium channel attenuates cardiac remodeling induced by chronic inhibition of nitric oxide synthesis].
|
J Cardiol
|
2003
|
0.75
|
|
71
|
Japan expects decrements in both the incidence and mortality of acute myocardial infarction in the modern era: likely or just a dream?
|
Circ J
|
2010
|
0.75
|
|
72
|
Signal transduction study using gene-targeted embryonic stem cells.
|
Methods Mol Biol
|
2003
|
0.75
|
|
73
|
Decreased mortality associated with statin treatment in patients with acute myocardial infarction and lymphotoxin-alpha C804A polymorphism.
|
Atherosclerosis
|
2013
|
0.75
|
|
74
|
Roles of systemic nitric oxide metabolites for human coronary circulation.
|
Cardiovasc Drugs Ther
|
2004
|
0.75
|
|
75
|
[The effect of erythropoietin on the improvement of cardiac function in patients with myocardial infarction].
|
Nihon Rinsho
|
2011
|
0.75
|
|
76
|
A calcium channel blocker amlodipine increases coronary blood flow via both adenosine- and NO-dependent mechanisms in ischemic hearts.
|
J Mol Cell Cardiol
|
2005
|
0.75
|