Published in Genes Immun on September 01, 2004
Initial sequencing and analysis of the human genome. Nature (2001) 212.86
GeneCards: a novel functional genomics compendium with automated data mining and query reformulation support. Bioinformatics (1998) 15.82
A gene map of the human genome. Science (1996) 14.32
A physical map of 30,000 human genes. Science (1998) 12.43
A physical map of the human genome. Nature (2001) 12.39
Chlamydial infection. Isolation of Chlamydia from patients with non-specific genital infection. Br J Vener Dis (1972) 7.92
E-cadherin germline mutations in familial gastric cancer. Nature (1998) 6.72
Guidelines for human gene nomenclature (1997). HUGO Nomenclature Committee. Genomics (1997) 6.44
Mechanisms of lactose utilization by lactic acid streptococci: enzymatic and genetic analyses. J Bacteriol (1970) 6.34
Targeted disruption of the mouse Caspase 8 gene ablates cell death induction by the TNF receptors, Fas/Apo1, and DR3 and is lethal prenatally. Immunity (1998) 6.07
Targeted disruption of the three Rb-related genes leads to loss of G(1) control and immortalization. Genes Dev (2000) 5.80
Spreading of T-cell autoimmunity to cryptic determinants of an autoantigen. Nature (1992) 5.47
The antigenic structure of proteins: a reappraisal. Annu Rev Immunol (1984) 5.31
The complete human olfactory subgenome. Genome Res (2001) 5.10
Transcription and processing of intervening sequences in yeast tRNA genes. Cell (1978) 5.07
Dynamic molecular combing: stretching the whole human genome for high-resolution studies. Science (1997) 4.86
A new highly penetrant form of obesity due to deletions on chromosome 16p11.2. Nature (2010) 4.52
Dominance and crypticity of T cell antigenic determinants. Annu Rev Immunol (1993) 4.23
Rapid diagnosis of pulmonary tuberculosis by using Roche AMPLICOR Mycobacterium tuberculosis PCR test. J Clin Microbiol (1995) 4.11
Oral tolerance: immunologic mechanisms and treatment of animal and human organ-specific autoimmune diseases by oral administration of autoantigens. Annu Rev Immunol (1994) 4.07
A gene related to Caenorhabditis elegans spermatogenesis factor fer-1 is mutated in limb-girdle muscular dystrophy type 2B. Nat Genet (1998) 3.76
Chromosomal mapping of two genetic loci associated with blood-pressure regulation in hereditary hypertensive rats. Nature (1991) 3.74
Age differences in the frontal lateralization of verbal and spatial working memory revealed by PET. J Cogn Neurosci (2000) 3.66
GeneCards: integrating information about genes, proteins and diseases. Trends Genet (1997) 3.62
Chlamydial infections of the cervix. Br J Vener Dis (1974) 3.48
Mutations in the gene encoding mevalonate kinase cause hyper-IgD and periodic fever syndrome. International Hyper-IgD Study Group. Nat Genet (1999) 3.44
A missense mutation in a highly conserved region of CASQ2 is associated with autosomal recessive catecholamine-induced polymorphic ventricular tachycardia in Bedouin families from Israel. Am J Hum Genet (2001) 3.38
IL-17 stimulates granulopoiesis in mice: use of an alternate, novel gene therapy-derived method for in vivo evaluation of cytokines. J Immunol (1998) 3.37
Tumor necrosis factor-alpha. A mediator of focal ischemic brain injury. Stroke (1997) 3.26
Evidence of a healthy volunteer effect in the prostate, lung, colorectal, and ovarian cancer screening trial. Am J Epidemiol (2007) 3.24
Adjuvant therapy in stage I and stage II epithelial ovarian cancer. Results of two prospective randomized trials. N Engl J Med (1990) 2.97
Odorant-sensitive adenylate cyclase may mediate olfactory reception. Nature (1985) 2.94
Bacteremia and fungemia complicating neoplastic disease. A study of 364 cases. Am J Med (1977) 2.92
Fatigue therapy in multiple sclerosis: results of a double-blind, randomized, parallel trial of amantadine, pemoline, and placebo. Neurology (1995) 2.90
Identification of the gene causing mucolipidosis type IV. Nat Genet (2000) 2.87
Single breath diffusing capacity in a representative sample of the population of Michigan, a large industrial state. Predicted values, lower limits of normal, and frequencies of abnormality by smoking history. Am Rev Respir Dis (1983) 2.83
Cloning of yeast transfer RNA genes in Escherichia coli. Science (1977) 2.73
Complete amino acid sequence of a papain-solubilized human histocompatibility antigen, HLA-B7. 2. Sequence determination and search for homologies. Biochemistry (1979) 2.71
The UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase gene is mutated in recessive hereditary inclusion body myopathy. Nat Genet (2001) 2.71
Surgical complication outcome (SCOUT) score: a new method to evaluate quality of care in vascular surgery. J Vasc Surg (1997) 2.67
Fatty and fibroglandular tissue volumes in the breasts of women 20-83 years old: comparison of X-ray mammography and computer-assisted MR imaging. AJR Am J Roentgenol (1997) 2.66
The choice of T-cell epitopes utilized on a protein antigen depends on multiple factors distant from, as well as at the determinant site. Immunol Rev (1987) 2.56
The UDP glycosyltransferase gene superfamily: recommended nomenclature update based on evolutionary divergence. Pharmacogenetics (1997) 2.55
Spontaneous mutations in the CsrRS two-component regulatory system of Streptococcus pyogenes result in enhanced virulence in a murine model of skin and soft tissue infection. J Infect Dis (2001) 2.51
Effect of tumor necrosis factor alpha on mitogen-activated human B cells. J Exp Med (1987) 2.42
Series of exon-skipping events in the elastic spring region of titin as the structural basis for myofibrillar elastic diversity. Circ Res (2000) 2.39
Disruption of hsp90 function results in degradation of the death domain kinase, receptor-interacting protein (RIP), and blockage of tumor necrosis factor-induced nuclear factor-kappaB activation. J Biol Chem (2000) 2.37
Cell wall and protoplast isoperoxidases in relation to injury, indoleacetic Acid, and ethylene effects. Plant Physiol (1974) 2.36
A randomized trial of varenicline (Chantix) for the treatment of spinocerebellar ataxia type 3. Neurology (2012) 2.34
Quasi-hexagonal molecular packing in collagen fibrils. Nature (1980) 2.28
Surgical staging in endometrial cancer: clinical-pathologic findings of a prospective study. Obstet Gynecol (1984) 2.25
A pilot trial of Cop 1 in exacerbating-remitting multiple sclerosis. N Engl J Med (1987) 2.21
Haplotypes and gene expression implicate the MAPT region for Parkinson disease: the GenePD Study. Neurology (2008) 2.16
Early combination therapy (bromocriptine and levodopa) does not prevent motor fluctuations in Parkinson's disease. Neurology (1993) 2.16
The lipid world. Orig Life Evol Biosph (2001) 2.15
The olfactory receptor gene superfamily: data mining, classification, and nomenclature. Mamm Genome (2000) 2.15
Fine specificity of regulatory T cells. II. Suppressor and helper T cells are induced by different regions of hen egg-white lysozyme in a genetically nonresponder mouse strain. J Exp Med (1979) 2.12
Dichotomy of single-nucleotide polymorphism haplotypes in olfactory receptor genes and pseudogenes. Nat Genet (2000) 2.10
A single nucleotide polymorphism in the RAD51 gene modifies cancer risk in BRCA2 but not BRCA1 carriers. Proc Natl Acad Sci U S A (2001) 2.09
Phonons and the elastic moduli of collagen and muscle. Nature (1977) 2.09
Intuitive hypertext-based molecular identification of micro-organisms. Lancet (1999) 2.01
Olfactory receptor gene cluster on human chromosome 17: possible duplication of an ancestral receptor repertoire. Hum Mol Genet (1994) 2.00
Cognitive-behavioral therapy to reduce weight concerns improves smoking cessation outcome in weight-concerned women. J Consult Clin Psychol (2001) 1.99
The present status of the heterogeneity of fetal hemoglobin in beta-thalassemia: an attempt to unify some observations in thalassemia and related conditions. Ann N Y Acad Sci (1974) 1.99
Determination of the elastic constants of collagen by Brillouin light scattering. J Mol Biol (1979) 1.97
Central catheter infections: single- versus triple-lumen catheters. Influence of guide wires on infection rates when used for replacement of catheters. Am J Med (1988) 1.96
Changes in pulmonary function in workers exposed to vinyl chloride and polyvinyl chloride. Ann N Y Acad Sci (1975) 1.95
The limb-girdle muscular dystrophies--proposal for a new nomenclature. Neuromuscul Disord (1995) 1.95
Calpain 3 deficiency is associated with myonuclear apoptosis and profound perturbation of the IkappaB alpha/NF-kappaB pathway in limb-girdle muscular dystrophy type 2A. Nat Med (1999) 1.94
Heavy chain of HLA-A and HLA-B antigens is conformationally labile: a possible role for beta 2-microglobulin. Proc Natl Acad Sci U S A (1979) 1.93
Flexibility of the NSAID binding site in the structure of human cyclooxygenase-2. Nat Struct Biol (1996) 1.92
Polymorphisms in FKBP5 are associated with peritraumatic dissociation in medically injured children. Mol Psychiatry (2005) 1.91
Different functional specificity repertoires for suppressor and helper T cells. Immunol Rev (1978) 1.91
Epidemiologic study of 203 sibling pairs with Parkinson's disease: the GenePD study. Neurology (2002) 1.90
Why do young women smoke? I. Direct and interactive effects of environment, psychological characteristics and nicotinic cholinergic receptor genes. Mol Psychiatry (2006) 1.89
Sequence, structure, and evolution of a complete human olfactory receptor gene cluster. Genomics (2000) 1.88
Mean and instantaneous expiratory flows, FVC and FEV1: prediction equations from a probability sample of Michigan, a large industrial state. Bull Eur Physiopathol Respir (1987) 1.88
Vertebrate olfactory reception. Annu Rev Neurosci (1986) 1.87
Vacuoliting megalencephalic leukoencephalopathy with subcortical cysts, mapped to chromosome 22qtel. Am J Hum Genet (2000) 1.79
Monocular elevation weakness and ptosis: an oculomotor fascicular syndrome? J Clin Neuroophthalmol (1991) 1.78
A randomized, double-blind, placebo-controlled trial of antidepressants in Parkinson disease. Neurology (2012) 1.77
Compositional genomes: prebiotic information transfer in mutually catalytic noncovalent assemblies. Proc Natl Acad Sci U S A (2000) 1.75
Volatile compounds produced in sterile fish muscle (Sebastes melanops) by Pseudomonas perolens. Appl Microbiol (1973) 1.73
Audit of emergency preoperative resuscitation. Br J Surg (1994) 1.73
Recommendations from the National Multiple Sclerosis Society Clinical Outcomes Assessment Task Force. Ann Neurol (1997) 1.72
The heavy chain of human histocompatibility antigen HLA-B7 contains an immunoglobulin-like region. Nature (1979) 1.70
Structure of insect fibrillar flight muscle in the presence and absence of ATP. J Mol Biol (1972) 1.70
Dysferlin is a plasma membrane protein and is expressed early in human development. Hum Mol Genet (1999) 1.69
Analysis of the primary structure of collagen for the origins of molecular packing. J Mol Biol (1973) 1.68
Genetic linkage of the Muckle-Wells syndrome to chromosome 1q44. Am J Hum Genet (1999) 1.68
Diagnostics of neisseriaceae and moraxellaceae by ribosomal DNA sequencing: ribosomal differentiation of medical microorganisms. J Clin Microbiol (2001) 1.66
Pneumocystis carinii pneumonia: a cluster of eleven cases. Ann Intern Med (1975) 1.66
Autosomal dominant lateral temporal epilepsy: clinical and genetic study of a large Basque pedigree linked to chromosome 10q. Ann Neurol (1999) 1.65
A phase II study of the histone deacetylase inhibitor vorinostat combined with tamoxifen for the treatment of patients with hormone therapy-resistant breast cancer. Br J Cancer (2011) 1.65
Interpretation of the meridional X-ray diffraction pattern from collagen fibres in terms of the known amino acid sequence. J Mol Biol (1977) 1.64