PubRank

Steven M Cramer

Author PubWeight™ 31.93‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Antibody variable region interactions with Protein A: implications for the development of generic purification processes. Biotechnol Bioeng 2005 1.06
2 Parallel synthesis and screening of polymers for nonviral gene delivery. Mol Pharm 2009 1.02
3 Binding capacity differences for antibodies and Fc-fusion proteins on protein A chromatographic materials. Biotechnol Bioeng 2007 0.89
4 High-throughput screening and quantitative structure-efficacy relationship models of potential displacer molecules for ion-exchange systems. Biotechnol Bioeng 2002 0.87
5 Characterization and modeling of nonlinear hydrophobic interaction chromatographic systems. J Chromatogr A 2011 0.84
6 Unique selectivity windows using selective displacers/eluents and mobile phase modifiers on hydroxyapatite. J Chromatogr A 2010 0.83
7 Parallel screening of selective and high-affinity displacers for proteins in ion-exchange systems. J Chromatogr A 2004 0.82
8 Chemoenzymatic synthesis and high-throughput screening of an aminoglycoside-polyamine library: identification of high-affinity displacers and DNA-binding ligands. J Am Chem Soc 2004 0.81
9 On-chip electrochromatography using sol-gel immobilized stationary phase with UV absorbance detection. J Chromatogr A 2004 0.81
10 Molecular simulations of multimodal ligand-protein binding: elucidation of binding sites and correlation with experiments. J Phys Chem B 2011 0.81
11 Protein interactions in hydrophobic charge induction chromatography (HCIC). Biotechnol Prog 2005 0.80
12 Investigation of protein binding affinity in multimodal chromatographic systems using a homologous protein library. J Chromatogr A 2009 0.80
13 Application of hydrophobic interaction displacement chromatography for an industrial protein purification. Biotechnol Bioeng 2003 0.80
14 Effects of urea induced protein conformational changes on ion exchange chromatographic behavior. J Chromatogr A 2010 0.80
15 Competitive adsorption of labeled and native protein in confocal laser scanning microscopy. Biotechnol Bioeng 2006 0.80
16 Investigation of DNA-binding properties of an aminoglycoside-polyamine library using quantitative structure-activity relationship (QSAR) models. J Chem Inf Model 2005 0.80
17 Detection of trace proteins in multicomponent mixtures using displacement chromatography. Anal Chem 2011 0.80
18 Protein adsorption isotherm behavior in hydrophobic interaction chromatography. J Chromatogr A 2007 0.79
19 Investigation of protein binding affinity and preferred orientations in ion exchange systems using a homologous protein library. Biotechnol Bioeng 2009 0.79
20 Evaluation and comparison of alternatives to Protein A chromatography Mimetic and hydrophobic charge induction chromatographic stationary phases. J Chromatogr A 2006 0.78
21 A priori prediction of adsorption isotherm parameters and chromatographic behavior in ion-exchange systems. Proc Natl Acad Sci U S A 2005 0.78
22 Classification of protein binding in hydroxyapatite chromatography: synergistic interactions on the molecular scale. Anal Chem 2011 0.78
23 Synthesis and characterization of fluorescent displacers for online monitoring of displacement chromatography. J Am Chem Soc 2008 0.78
24 Investigation of protein retention and selectivity in HIC systems using quantitative structure retention relationship models. Biotechnol Bioeng 2006 0.77
25 Multidimensional high-throughput screening of displacers. Anal Chem 2005 0.77
26 Prediction of protein retention times in gradient hydrophobic interaction chromatographic systems. J Chromatogr A 2007 0.77
27 Photopolymerized sol-gel monoliths for separations of glycosylated proteins and peptides in microfluidic chips. J Sep Sci 2013 0.77
28 Improved process analytical technology for protein a chromatography using predictive principal component analysis tools. Biotechnol Bioeng 2011 0.76
29 High-throughput screening for the development of a monoclonal antibody affinity precipitation step using ELP-z stimuli responsive biopolymers. Biotechnol Bioeng 2013 0.76
30 Evaluation of selectivity changes in HIC systems using a preferential interaction based analysis. Biotechnol Bioeng 2004 0.76
31 Identifying kinetically stable proteins with capillary electrophoresis. Protein Sci 2010 0.76
32 Affinity precipitation of a monoclonal antibody from an industrial harvest feedstock using an ELP-Z stimuli responsive biopolymer. Biotechnol Bioeng 2014 0.76
33 Evaluation of protein adsorption and preferred binding regions in multimodal chromatography using NMR. Proc Natl Acad Sci U S A 2010 0.76
34 ELP-z and ELP-zz capturing scaffolds for the purification of immunoglobulins by affinity precipitation. J Biotechnol 2012 0.76
35 Investigation into the molecular and thermodynamic basis of protein interactions in multimodal chromatography using functionalized nanoparticles. Langmuir 2014 0.76
36 Selective filling for patterning in microfluidic channels. Langmuir 2005 0.76
37 Use and optimization of a dual-flowrate loading strategy to maximize throughput in protein-a affinity chromatography. Biotechnol Prog 2004 0.76
38 Classification of protein adsorption and recovery at low salt conditions in hydrophobic interaction chromatographic systems. J Chromatogr A 2006 0.75
39 Characterization and design of chemically selective cationic displacers using a robotic high-throughput screen. Biotechnol Prog 2009 0.75
40 Prediction of the effect of mobile-phase salt type on protein retention and selectivity in anion exchange systems. Anal Chem 2003 0.75
41 Methods development in multimodal chromatography with mobile phase modifiers using the steric mass action model. J Chromatogr A 2013 0.75
42 Purification of monomeric mAb from associated aggregates using selective desorption chromatography in hydroxyapatite systems. Biotechnol Bioeng 2010 0.75
43 Effects of urea on selectivity and protein-ligand interactions in multimodal cation exchange chromatography. Langmuir 2012 0.75
44 Protein Binding Kinetics in Multimodal Systems: Implications for Protein Separations. Anal Chem 2017 0.75
45 Mechanistic studies of displacer-protein binding in chemically selective displacement systems using NMR and MD simulations. Biotechnol Bioeng 2009 0.75
46 Application of a spherical harmonics expansion approach for calculating ligand density distributions around proteins. J Phys Chem B 2014 0.75
47 Evaluation of selectivity in multimodal anion exchange systems: a priori prediction of protein retention and examination of mobile phase modifier effects. J Chromatogr A 2011 0.75
48 Phenylboronate chromatography selectively separates glycoproteins through the manipulation of electrostatic, charge transfer, and cis-diol interactions. Biotechnol J 2014 0.75
49 Investigation of multi-modal high-salt binding ion-exchange chromatography using quantitative structure-property relationship modeling. J Chromatogr A 2007 0.75
50 The effect of feed composition on the behavior of chemically selective displacement systems. J Chromatogr A 2010 0.75
51 Displacer concentration effects in displacement chromatography. Implications for trace solute detection. J Chromatogr A 2008 0.75
52 Identification of chemically selective displacers using parallel batch screening experiments and quantitative structure efficacy relationship models. Anal Chem 2003 0.75
53 Model-based process development for the purification of a modified human growth hormone using multimodal chromatography. Biotechnol Prog 2014 0.75
54 Evaluation of chemically selective displacer analogues for protein purification. Anal Chem 2009 0.75
55 Utilization of lysozyme charge ladders to examine the effects of protein surface charge distribution on binding affinity in ion exchange systems. Langmuir 2010 0.75
56 An affinity-based strategy for the design of selective displacers for the chromatographic separation of proteins. Langmuir 2008 0.75
57 Improving selectivity in multimodal chromatography using controlled pH gradient elution. J Chromatogr A 2012 0.75
58 Stationary phase effects on the dynamic affinity of low-molecular-mass displacers. J Chromatogr A 2002 0.75
59 Effect of pH changes on water release values in hydrophobic interaction chromatographic systems. J Chromatogr A 2005 0.75
60 Prediction of pH-dependent chromatographic behavior in ion-exchange systems. Anal Chem 2007 0.75
61 Chemically selective displacers for high-resolution protein separations in ion-exchange systems: effect of displacer-protein interactions. Anal Chem 2008 0.75
62 Selective displacement chromatography in multimodal cation exchange systems. J Chromatogr A 2011 0.75
63 Protein-surface interaction maps for ion-exchange chromatography. Langmuir 2011 0.75
64 Modeling of adsorption in hydrophobic interaction chromatography systems using a preferential interaction quadratic isotherm. J Chromatogr A 2003 0.75
65 Mobile phase modifier effects in multimodal cation exchange chromatography. Biotechnol Bioeng 2011 0.75
66 Probing multimodal ligand binding regions on ubiquitin using nuclear magnetic resonance, chromatography, and molecular dynamics simulations. J Chromatogr A 2012 0.75