Published in Nat Struct Mol Biol on August 01, 2004
Stretchy proteins on stretchy substrates: the important elements of integrin-mediated rigidity sensing. Dev Cell (2010) 2.65
Differential labeling of myosin V heads with quantum dots allows direct visualization of hand-over-hand processivity. Biophys J (2005) 2.31
Force-dependent stepping kinetics of myosin-V. Biophys J (2005) 1.88
Mechanochemical analysis of DNA gyrase using rotor bead tracking. Nature (2006) 1.83
Myosin V from head to tail. Cell Mol Life Sci (2008) 1.76
Filopodia act as phagocytic tentacles and pull with discrete steps and a load-dependent velocity. Proc Natl Acad Sci U S A (2007) 1.72
Kinetic and equilibrium analysis of the myosin ATPase. Methods Enzymol (2009) 1.66
Myosin V and Kinesin act as tethers to enhance each others' processivity. Proc Natl Acad Sci U S A (2008) 1.65
Elastic lever-arm model for myosin V. Biophys J (2005) 1.62
Load-dependent ADP binding to myosins V and VI: implications for subunit coordination and function. Proc Natl Acad Sci U S A (2008) 1.61
Stepwise movements in vesicle transport of HER2 by motor proteins in living cells. Biophys J (2007) 1.55
Adaptability of myosin V studied by simultaneous detection of position and orientation. EMBO J (2006) 1.40
Direct observation of the myosin-Va power stroke and its reversal. Nat Struct Mol Biol (2010) 1.28
Load and Pi control flux through the branched kinetic cycle of myosin V. J Biol Chem (2008) 1.24
Myosin Va and myosin VI coordinate their steps while engaged in an in vitro tug of war during cargo transport. Proc Natl Acad Sci U S A (2011) 1.23
Mutation of a conserved glycine in the SH1-SH2 helix affects the load-dependent kinetics of myosin. Biophys J (2006) 1.15
Velocity, processivity, and individual steps of single myosin V molecules in live cells. Biophys J (2009) 1.15
Melanosomes transported by myosin-V in Xenopus melanophores perform slow 35 nm steps. Biophys J (2005) 1.11
Collective dynamics of elastically coupled myosin V motors. J Biol Chem (2012) 1.06
Tilting and wobble of myosin V by high-speed single-molecule polarized fluorescence microscopy. Biophys J (2013) 1.01
Myosin V stepping mechanism. Proc Natl Acad Sci U S A (2007) 1.01
An elastically tethered viscous load imposes a regular gait on the motion of myosin-V. Simulation of the effect of transient force relaxation on a stochastic process. J R Soc Interface (2006) 1.01
Detailed tuning of structure and intramolecular communication are dispensable for processive motion of myosin VI. Biophys J (2011) 1.00
The stepping pattern of myosin X is adapted for processive motility on bundled actin. Biophys J (2010) 0.99
Mechanochemical model for myosin V. Proc Natl Acad Sci U S A (2009) 0.97
Mechanoenzymes under superstall and large assisting loads reveal structural features. Proc Natl Acad Sci U S A (2007) 0.96
Kinetics and thermodynamics of the rate-limiting conformational change in the actomyosin V mechanochemical cycle. J Mol Biol (2011) 0.96
Dwell time symmetry in random walks and molecular motors. Biophys J (2007) 0.94
An alternative reaction pathway of F1-ATPase suggested by rotation without 80 degrees/40 degrees substeps of a sluggish mutant at low ATP. Biophys J (2005) 0.93
Sarcomere length nanometry in rat neonatal cardiomyocytes expressed with α-actinin-AcGFP in Z discs. J Gen Physiol (2014) 0.91
Switch II mutants reveal coupling between the nucleotide- and actin-binding regions in myosin V. Biophys J (2012) 0.91
Robust processivity of myosin V under off-axis loads. Nat Chem Biol (2010) 0.91
Design principles governing the motility of myosin V. Proc Natl Acad Sci U S A (2013) 0.90
Flexible light-chain and helical structure of F-actin explain the movement and step size of myosin-VI. Biophys J (2006) 0.88
Structural dynamics of myosin 5 during processive motion revealed by interferometric scattering microscopy. Elife (2015) 0.88
Redundant mechanisms for anaphase chromosome movements: crane-fly spermatocyte spindles normally use actin filaments but also can function without them. Protoplasma (2005) 0.88
Switching of myosin-V motion between the lever-arm swing and brownian search-and-catch. Nat Commun (2012) 0.87
The energetics of allosteric regulation of ADP release from myosin heads. Phys Chem Chem Phys (2009) 0.87
Interrogating biology with force: single molecule high-resolution measurements with optical tweezers. Biophys J (2013) 0.87
Motor proteins and molecular motors: how to operate machines at the nanoscale. J Phys Condens Matter (2013) 0.87
Delineating cooperative responses of processive motors in living cells. Proc Natl Acad Sci U S A (2014) 0.85
Lever-arm mechanics of processive myosins. Biophys J (2011) 0.85
Aluminium causes variable responses in actin filament cytoskeleton of the root tip cells of Triticum turgidum. Protoplasma (2005) 0.84
Coarse-Grained Structural Modeling of Molecular Motors Using Multibody Dynamics. Cell Mol Bioeng (2009) 0.84
Chemomechanical coupling and motor cycles of myosin V. Biophys J (2011) 0.84
Magnesium impacts myosin V motor activity by altering key conformational changes in the mechanochemical cycle. Biochemistry (2013) 0.82
A kinetic model describing the processivity of myosin-V. Biophys J (2006) 0.82
Tuning myosin-driven sorting on cellular actin networks. Elife (2015) 0.82
Holding the reins on myosin V. Proc Natl Acad Sci U S A (2005) 0.81
Kinetic Adaptations of Myosins for Their Diverse Cellular Functions. Traffic (2016) 0.79
How the Load and the Nucleotide State Affect the Actin Filament Binding Mode of the Molecular Motor Myosin V. J Korean Phys Soc (2008) 0.78
D-loop of actin differently regulates the motor function of myosins II and V. J Biol Chem (2009) 0.78
A branched kinetic scheme describes the mechanochemical coupling of Myosin Va processivity in response to substrate. Biophys J (2012) 0.77
Myosin V passing over Arp2/3 junctions: branching ratio calculated from the elastic lever arm model. Biophys J (2008) 0.77
Magnesium modulates actin binding and ADP release in myosin motors. J Biol Chem (2014) 0.77
The path to visualization of walking myosin V by high-speed atomic force microscopy. Biophys Rev (2014) 0.76
Regular gaits and optimal velocities for motor proteins. Biophys J (2008) 0.75
Dwell time distributions of the molecular motor myosin V. PLoS One (2013) 0.75
The Role of the Cytoskeleton and Myosin-Vc in the Targeting of KCa3.1 to the Basolateral Membrane of Polarized Epithelial Cells. Front Physiol (2017) 0.75
Watching the walk: observing chemo-mechanical coupling in a processive myosin motor. HFSP J (2009) 0.75
Myosin V is a biological Brownian machine. Biophysics (Nagoya-shi) (2014) 0.75
Phenomenological analysis of ATP dependence of motor proteins. PLoS One (2012) 0.75
Biphasic Effect of Profilin Impacts the Formin mDia1 Force-Sensing Mechanism in Actin Polymerization. Biophys J (2017) 0.75
Microscopic analysis of polymerization dynamics with individual actin filaments. Nat Cell Biol (2002) 3.41
Overlapping hand-over-hand mechanism of single molecular motility of cytoplasmic dynein. Proc Natl Acad Sci U S A (2006) 2.87
Alternate fast and slow stepping of a heterodimeric kinesin molecule. Nat Cell Biol (2003) 2.74
The structural basis for activation of the Rab Ypt1p by the TRAPP membrane-tethering complexes. Cell (2008) 2.61
Chemomechanical coupling of the forward and backward steps of single kinesin molecules. Nat Cell Biol (2002) 2.56
Single-molecule protein unfolding and translocation by an ATP-fueled proteolytic machine. Cell (2011) 2.40
In vivo real-time tracking of single quantum dots conjugated with monoclonal anti-HER2 antibody in tumors of mice. Cancer Res (2007) 2.19
Myosin V is a left-handed spiral motor on the right-handed actin helix. Nat Struct Biol (2002) 1.95
Actin network architecture can determine myosin motor activity. Science (2012) 1.89
Loading direction regulates the affinity of ADP for kinesin. Nat Struct Biol (2003) 1.80
The bidirectional depolymerizer MCAK generates force by disassembling both microtubule ends. Nat Cell Biol (2011) 1.70
The ATPase cycle mechanism of the DEAD-box rRNA helicase, DbpA. J Mol Biol (2007) 1.70
Load-dependent ADP binding to myosins V and VI: implications for subunit coordination and function. Proc Natl Acad Sci U S A (2008) 1.61
Direct observation of the myosin Va recovery stroke that contributes to unidirectional stepping along actin. PLoS Biol (2011) 1.57
Energetics and kinetics of cooperative cofilin-actin filament interactions. J Mol Biol (2006) 1.56
Stepwise movements in vesicle transport of HER2 by motor proteins in living cells. Biophys J (2007) 1.55
Processivity of the single-headed kinesin KIF1A through biased binding to tubulin. Nature (2003) 1.55
Kinesin-microtubule binding depends on both nucleotide state and loading direction. Proc Natl Acad Sci U S A (2002) 1.54
Magnesium, ADP, and actin binding linkage of myosin V: evidence for multiple myosin V-ADP and actomyosin V-ADP states. Biochemistry (2005) 1.53
Mechanism of nucleotide binding to actomyosin VI: evidence for allosteric head-head communication. J Biol Chem (2004) 1.50
Cofilin-linked changes in actin filament flexibility promote severing. Biophys J (2011) 1.47
Nonlinear elasticity and an 8-nm working stroke of single myosin molecules in myofilaments. Science (2010) 1.41
Identification of small-molecule inhibitors of autotaxin that inhibit melanoma cell migration and invasion. Mol Cancer Ther (2008) 1.34
Actin filament remodeling by actin depolymerization factor/cofilin. Proc Natl Acad Sci U S A (2010) 1.28
Pathway of ATP utilization and duplex rRNA unwinding by the DEAD-box helicase, DbpA. Proc Natl Acad Sci U S A (2010) 1.28
Thermodynamics of nucleotide binding to actomyosin V and VI: a positive heat capacity change accompanies strong ADP binding. Biochemistry (2005) 1.24
Physiological functions of the giant elastic protein titin in mammalian striated muscle. J Physiol Sci (2008) 1.21
Identification of a strong binding site for kinesin on the microtubule using mutant analysis of tubulin. EMBO J (2006) 1.18
In vivo nano-imaging of membrane dynamics in metastatic tumor cells using quantum dots. J Biol Chem (2009) 1.17
Probing the mechanical architecture of the vertebrate meiotic spindle. Nat Methods (2009) 1.17
Mechanism of Mss116 ATPase reveals functional diversity of DEAD-Box proteins. J Mol Biol (2011) 1.17
Vertebrate myosin VIIb is a high duty ratio motor adapted for generating and maintaining tension. J Biol Chem (2005) 1.16
Insights regarding guanine nucleotide exchange from the structure of a DENN-domain protein complexed with its Rab GTPase substrate. Proc Natl Acad Sci U S A (2011) 1.15
Insights into the micromechanical properties of the metaphase spindle. Cell (2011) 1.15
Single-molecule imaging of cooperative assembly of gamma-hemolysin on erythrocyte membranes. EMBO J (2003) 1.14
Disuse-induced preferential loss of the giant protein titin depresses muscle performance via abnormal sarcomeric organization. J Gen Physiol (2008) 1.13
Three-dimensional nanometry of vesicle transport in living cells using dual-focus imaging optics. Biochem Biophys Res Commun (2007) 1.11
Planar polarity of multiciliated ependymal cells involves the anterior migration of basal bodies regulated by non-muscle myosin II. Development (2010) 1.10
Intracellular imaging of targeted proteins labeled with quantum dots. Exp Cell Res (2008) 1.10
Actin-induced closure of the actin-binding cleft of smooth muscle myosin. J Biol Chem (2002) 1.10
Myosin-X induces filopodia by multiple elongation mechanism. J Biol Chem (2010) 1.10
Structural and energetic analysis of activation by a cyclic nucleotide binding domain. J Mol Biol (2008) 1.10
Myosin isoform determines the conformational dynamics and cooperativity of actin filaments in the strongly bound actomyosin complex. J Mol Biol (2009) 1.10
Equilibrium and transition between single- and double-headed binding of kinesin as revealed by single-molecule mechanics. Biophys J (2003) 1.09
A nationwide survey of outdoor radon concentration in Japan. J Environ Radioact (2003) 1.09
Biased binding of single molecules and continuous movement of multiple molecules of truncated single-headed kinesin. Biophys J (2004) 1.08
Visualization and force measurement of branching by Arp2/3 complex and N-WASP in actin filament. Biochem Biophys Res Commun (2002) 1.08
Elementary steps of the cross-bridge cycle in bovine myocardium with and without regulatory proteins. Biophys J (2002) 1.07
Highly thermosensitive Ca dynamics in a HeLa cell through IP(3) receptors. HFSP J (2009) 1.07
Nonlinear force-length relationship in the ADP-induced contraction of skeletal myofibrils. Biophys J (2007) 1.07
Human myosin Vc is a low duty ratio nonprocessive motor. J Biol Chem (2007) 1.07
Motility of myosin V regulated by the dissociation of single calmodulin. Nat Struct Mol Biol (2005) 1.06
ATP utilization and RNA conformational rearrangement by DEAD-box proteins. Annu Rev Biophys (2012) 1.05
Key residues on microtubule responsible for activation of kinesin ATPase. EMBO J (2010) 1.04
A nanoparticle-based ratiometric and self-calibrated fluorescent thermometer for single living cells. ACS Nano (2013) 1.03
Walking nanothermometers: spatiotemporal temperature measurement of transported acidic organelles in single living cells. Lab Chip (2012) 1.02
Microscopic detection of thermogenesis in a single HeLa cell. Biophys J (2007) 1.02
Identification of cation-binding sites on actin that drive polymerization and modulate bending stiffness. Proc Natl Acad Sci U S A (2012) 1.01
Coordination of kinesin's two heads studied with mutant heterodimers. Proc Natl Acad Sci U S A (2002) 1.01
Kinetic analysis of the guanine nucleotide exchange activity of TRAPP, a multimeric Ypt1p exchange factor. J Mol Biol (2009) 1.01
Equilibrium and kinetic analysis of nucleotide binding to the DEAD-box RNA helicase DbpA. Biochemistry (2005) 1.00
Troponin and titin coordinately regulate length-dependent activation in skinned porcine ventricular muscle. J Gen Physiol (2008) 0.99
Controlling pore assembly of staphylococcal gamma-haemolysin by low temperature and by disulphide bond formation in double-cysteine LukF mutants. Mol Microbiol (2002) 0.99
In vivo single molecular imaging and sentinel node navigation by nanotechnology for molecular targeting drug-delivery systems and tailor-made medicine. Breast Cancer (2008) 0.99
The tail domain of myosin Va modulates actin binding to one head. J Biol Chem (2006) 0.99
Take advantage of time in your experiments: a guide to simple, informative kinetics assays. Mol Biol Cell (2013) 0.99
Identification of three distinct functional sites of insulin-mediated GLUT4 trafficking in adipocytes using quantitative single molecule imaging. Mol Biol Cell (2010) 0.99
Structure-based analysis of Toxoplasma gondii profilin: a parasite-specific motif is required for recognition by Toll-like receptor 11. J Mol Biol (2010) 0.98
Systematic comparison of in vitro motile properties between Chlamydomonas wild-type and mutant outer arm dyneins each lacking one of the three heavy chains. J Biol Chem (2009) 0.98
Competitive displacement of cofilin can promote actin filament severing. Biochem Biophys Res Commun (2013) 0.96
Inter-sarcomere coordination in muscle revealed through individual sarcomere response to quick stretch. Proc Natl Acad Sci U S A (2009) 0.96
Titin and troponin: central players in the frank-starling mechanism of the heart. Curr Cardiol Rev (2009) 0.96
Molecular origins of cofilin-linked changes in actin filament mechanics. J Mol Biol (2013) 0.95
Effects of solution crowding on actin polymerization reveal the energetic basis for nucleotide-dependent filament stability. J Mol Biol (2008) 0.93
Hydrodynamic characterization of the DEAD-box RNA helicase DbpA. J Mol Biol (2005) 0.92
Temperature change does not affect force between regulated actin filaments and heavy meromyosin in single-molecule experiments. J Physiol (2006) 0.92
A survey of indoor workplace radon concentration in Japan. J Environ Radioact (2006) 0.92
Sarcomere length nanometry in rat neonatal cardiomyocytes expressed with α-actinin-AcGFP in Z discs. J Gen Physiol (2014) 0.91
A myosin V inhibitor based on privileged chemical scaffolds. Angew Chem Int Ed Engl (2010) 0.91
A novel method of thermal activation and temperature measurement in the microscopic region around single living cells. J Neurosci Methods (2004) 0.91
Robust processivity of myosin V under off-axis loads. Nat Chem Biol (2010) 0.91
Kinetic analysis of autotaxin reveals substrate-specific catalytic pathways and a mechanism for lysophosphatidic acid distribution. J Biol Chem (2011) 0.91
Reduction in nonfluorescence state of quantum dots on an immunofluorescence staining. Biochem Biophys Res Commun (2006) 0.91
Dynamics of different-sized solid-state nanocrystals as tracers for a drug-delivery system in the interstitium of a human tumor xenograft. Breast Cancer Res (2009) 0.90
Myocardial sarcomeres spontaneously oscillate with the period of heartbeat under physiological conditions. Biochem Biophys Res Commun (2006) 0.90
Mechanical distortion of single actin filaments induced by external force: detection by fluorescence imaging. Biophys J (2009) 0.90
Single particle tracking confirms that multivalent Tat protein transduction domain-induced heparan sulfate proteoglycan cross-linkage activates Rac1 for internalization. J Biol Chem (2011) 0.89
Length-dependent activation and auto-oscillation in skeletal myofibrils at partial activation by Ca2+. Biochem Biophys Res Commun (2007) 0.89
Real-time measurement of the length of a single sarcomere in rat ventricular myocytes: a novel analysis with quantum dots. Am J Physiol Cell Physiol (2011) 0.89
Titin-based regulations of diastolic and systolic functions of mammalian cardiac muscle. J Mol Cell Cardiol (2009) 0.89
Single-molecule visualization of environment-sensitive fluorophores inserted into cell membranes by staphylococcal gamma-hemolysin. Biochemistry (2006) 0.89
A new muscle contractile system composed of a thick filament lattice and a single actin filament. Biophys J (2005) 0.87