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1
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Probes for narcotic receptor-mediated phenomena. 33. Construction of a strained trans-5,6-ring system by displacement of a nitro-activated aromatic fluorine. synthesis of the penultimate oxide-bridged phenylmorphans.
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J Org Chem
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2004
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1.35
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2
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Cannabilactones: a novel class of CB2 selective agonists with peripheral analgesic activity.
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J Med Chem
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2007
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1.19
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3
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Probes for narcotic receptor mediated phenomena. Part 28: new opioid antagonists from enantiomeric analogues of 5-(3-hydroxyphenyl)-N-phenylethylmorphan.
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Bioorg Med Chem
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2002
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1.13
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4
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A 4'-C-ethynyl-2',3'-dideoxynucleoside analogue highlights the role of the 3'-OH in anti-HIV active 4'-C-ethynyl-2'-deoxy nucleosides.
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J Med Chem
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2004
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1.11
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5
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Adamantyl cannabinoids: a novel class of cannabinergic ligands.
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J Med Chem
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2005
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1.09
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6
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Chemistry of the diazeniumdiolates. O- versus N-alkylation of the RNH[N(O)NO](-) ion.
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J Am Chem Soc
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2004
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1.02
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7
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High affinity hydroxypiperidine analogues of 4-(2-benzhydryloxyethyl)-1-(4-fluorobenzyl)piperidine for the dopamine transporter: stereospecific interactions in vitro and in vivo.
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J Med Chem
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2003
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0.90
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8
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Dual probes for the dopamine transporter and sigma1 receptors: novel piperazinyl alkyl-bis(4'-fluorophenyl)amine analogues as potential cocaine-abuse therapeutic agents.
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J Med Chem
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2003
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0.89
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9
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Understanding how the herpes thymidine kinase orchestrates optimal sugar and nucleobase conformations to accommodate its substrate at the active site: a chemical approach.
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J Am Chem Soc
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2005
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0.87
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10
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Interaction of cis-(6-benzhydrylpiperidin-3-yl)benzylamine analogues with monoamine transporters: structure-activity relationship study of structurally constrained 3,6-disubstituted piperidine analogues of (2,2-diphenylethyl)-[1-(4-fluorobenzyl)piperidin-4-ylmethyl]amine.
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J Med Chem
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2003
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0.87
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11
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Synthesis of a conformationally locked version of puromycin amino nucleoside.
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Org Lett
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2002
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0.84
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12
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Ligand effects on charge transport in platinum(II) acetylides.
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J Am Chem Soc
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2003
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0.83
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13
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A conformationally locked analogue of the anti-HIV agent stavudine. An important correlation between pseudorotation and maximum amplitude.
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J Med Chem
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2003
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0.83
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14
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Synthesis, nicotinic acetylcholine receptor binding affinities, and molecular modeling of constrained epibatidine analogues.
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J Med Chem
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2003
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0.79
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15
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X-ray studies on ligands.
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Biopolymers
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2002
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0.79
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16
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Comprehensive structural studies of 2',3'-difluorinated nucleosides: comparison of theory, solution, and solid state.
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J Am Chem Soc
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2008
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0.79
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17
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Crystal structures of dipeptides containing the Dmt-Tic pharmacophore.
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J Med Chem
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2002
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0.78
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18
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Synthesis and conformational analysis of a locked analogue of carbovir built on a bicyclo[3.1.0]hex-2-enyl template.
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Nucleosides Nucleotides Nucleic Acids
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2003
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0.77
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19
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Functionalization of the alicyclic skeleton of epibatidine: synthesis and nicotinic acetylcholine receptor binding affinities of epibatidine analogues.
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Org Biomol Chem
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2003
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0.76
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20
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(1R)-2-[(3R,4S)-3-Methyl-4-(N-phenyl-N-propionylamino)piperidin-1-yl]-1-phenylethyl p-bromobenzoate and N-[(3R,4S)-1-[(2S)-2-(4-bromophenyl)-2-hydroxyethyl]-3-methyl-piperidin-4-yl]-N-phenylacrylamide.
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Acta Crystallogr C
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2002
|
0.75
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|
21
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Synthesis and modeling study of (2S,5R,6R)- and (2S,5R,6S)-6-hydroxy- 8-(1-decynyl)-benzolactam-V8 as protein kinase C modulators.
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Org Lett
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2002
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0.75
|
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22
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Coordination chemistry of the water-soluble ligand TPPTP and formation of a [Mo(CO)5(m-TPPTP)] monolayer on an alumina surface.
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Inorg Chem
|
2003
|
0.75
|
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23
|
Diaryldimethylpiperazine ligands with mu- and delta-opioid receptor affinity: Synthesis of (+)-4-[(alphaR)-alpha-(4-allyl-(2S,5S)-dimethylpiperazin-1-yl)-(3-hydroxyphenyl)methyl]-N-ethyl-N-phenylbenzamide and (-)-4-[(alphaR)-alpha-(2S,5S)-dimethylpiperazin-1-yl)-(3-hydroxyphenyl)methyl]-N-ethyl-N-phenylbenzamide.
|
Bioorg Med Chem
|
2003
|
0.75
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