Published in Toxicol Appl Pharmacol on September 01, 2004
Safety of tenofovir use during pregnancy: early growth outcomes in HIV-exposed uninfected infants. AIDS (2012) 2.19
Neurodevelopment and in utero antiretroviral exposure of HIV-exposed uninfected infants. Pediatrics (2010) 1.22
Characterization of the main placental cytokine profiles from HIV-1-infected pregnant women treated with anti-retroviral drugs in France. Clin Exp Immunol (2007) 1.19
Lung cancer in HIV infected patients: facts, questions and challenges. Thorax (2006) 1.13
Progressive mitochondrial compromise in brains and livers of primates exposed in utero to nucleoside reverse transcriptase inhibitors (NRTIs). Toxicol Sci (2010) 1.08
Safety of perinatal exposure to antiretroviral medications: developmental outcomes in infants. Pediatr Infect Dis J (2013) 1.05
Elevated frequencies of micronucleated erythrocytes in infants exposed to zidovudine in utero and postpartum to prevent mother-to-child transmission of HIV. Environ Mol Mutagen (2007) 1.03
Perinatal exposure of patas monkeys to antiretroviral nucleoside reverse-transcriptase inhibitors induces genotoxicity persistent for up to 3 years of age. J Infect Dis (2013) 0.92
Effects of in utero antiretroviral exposure on mitochondrial DNA levels, mitochondrial function and oxidative stress. HIV Med (2011) 0.91
Zidovudine and Lamivudine for HIV Infection. Clin Med Rev Ther (2010) 0.89
Transplacental carcinogenesis with dibenzo[def,p]chrysene (DBC): timing of maternal exposures determines target tissue response in offspring. Cancer Lett (2011) 0.88
Human inter-individual variability in metabolism and genotoxic response to zidovudine. Toxicol Appl Pharmacol (2007) 0.87
Short communication: The relationship between mitochondrial dysfunction and insulin resistance in HIV-infected children receiving antiretroviral therapy. AIDS Res Hum Retroviruses (2013) 0.86
In utero exposure of female CD-1 Mice to AZT and/or 3TC: I. Persistence of microscopic lesions in cardiac tissue. Cardiovasc Toxicol (2010) 0.86
Lung Malignancies in HIV Infection. Semin Respir Crit Care Med (2016) 0.85
Mutational analysis of the mitochondrial tRNA genes and flanking regions in umbilical cord tissue from uninfected infants receiving AZT-based therapies for prophylaxis of HIV-1. Environ Mol Mutagen (2009) 0.81
WR1065 mitigates AZT-ddI-induced mutagenesis and inhibits viral replication. Environ Mol Mutagen (2009) 0.81
Relevance of experimental models for investigation of genotoxicity induced by antiretroviral therapy during human pregnancy. Mutat Res (2008) 0.81
Safety of in utero and neonatal antiretroviral exposure: cognitive and academic outcomes in HIV-exposed, uninfected children 5-13 years of age. Pediatr Infect Dis J (2014) 0.80
Inhibition of NF-κB activation sensitizes U937 cells to 3'-azido-3'-deoxythymidine induced apoptosis. Cell Death Dis (2010) 0.80
Fetal consequences of maternal antiretroviral nucleoside reverse transcriptase inhibitor use in human and nonhuman primate pregnancy. Curr Opin Pediatr (2015) 0.78
German-Austrian recommendations for HIV1-therapy in pregnancy and in HIV1-exposed newborn, update 2008. Eur J Med Res (2009) 0.78
A computational model of mitochondrial AZT metabolism. Biochem J (2005) 0.77
The PHACS SMARTT Study: Assessment of the Safety of In Utero Exposure to Antiretroviral Drugs. Front Immunol (2016) 0.76
Mitochondrial compromise in 3-year old patas monkeys exposed in utero to human-equivalent antiretroviral therapies. Environ Mol Mutagen (2016) 0.75
Biomarkers in toxicology and risk assessment: informing critical dose-response relationships. Chem Res Toxicol (2007) 2.53
Long-term mitochondrial toxicity in HIV-uninfected infants born to HIV-infected mothers. J Acquir Immune Defic Syndr (2003) 1.44
Mitochondrial toxicity in hearts of CD-1 mice following perinatal exposure to AZT, 3TC, or AZT/3TC in combination. Environ Mol Mutagen (2007) 1.10
Centrosomal amplification and aneuploidy induced by the antiretroviral drug AZT in hamster and human cells. Mutat Res (2009) 1.09
Molecular dosimetry of 1,2,3,4-diepoxybutane-induced DNA-DNA cross-links in B6C3F1 mice and F344 rats exposed to 1,3-butadiene by inhalation. Cancer Res (2009) 1.09
Mitochondrial damage and DNA depletion in cord blood and umbilical cord from infants exposed in utero to Combivir. AIDS (2004) 1.04
Morphological and molecular course of mitochondrial pathology in cultured human cells exposed long-term to Zidovudine. Environ Mol Mutagen (2007) 1.02
Genotoxicity assessed by the comet and GPA assays following in vitro exposure of human lymphoblastoid cells (H9) or perinatal exposure of mother-child pairs to AZT or AZT-3TC. Environ Mol Mutagen (2007) 1.01
Semiquantitation of polycyclic aromatic hydrocarbon-DNA adducts in human esophagus by immunohistochemistry and the automated cellular imaging system. Cancer Epidemiol Biomarkers Prev (2002) 1.01
Transplacental carcinogenicity of 3'-azido-3'-deoxythymidine in B6C3F1 mice and F344 rats. Environ Mol Mutagen (2007) 1.00
Analysis of diepoxide-specific cyclic N-terminal globin adducts in mice and rats after inhalation exposure to 1,3-butadiene. Cancer Res (2004) 0.99
Mutagenicity of zidovudine, lamivudine, and abacavir following in vitro exposure of human lymphoblastoid cells or in utero exposure of CD-1 mice to single agents or drug combinations. Environ Mol Mutagen (2007) 0.99
Mechanistic basis for nonlinear dose-response relationships for low-dose radiation-induced stochastic effects. Nonlinearity Biol Toxicol Med (2003) 0.98
Persistence and repair of bifunctional DNA adducts in tissues of laboratory animals exposed to 1,3-butadiene by inhalation. Chem Res Toxicol (2011) 0.97
1,3-Butadiene: Biomarkers and application to risk assessment. Chem Biol Interact (2010) 0.97
Relative mutagenic potencies of several nucleoside analogs, alone or in drug pairs, at the HPRT and TK loci of human TK6 lymphoblastoid cells. Environ Mol Mutagen (2007) 0.96
Exposure-response of 1,2:3,4-diepoxybutane-specific N-terminal valine adducts in mice and rats after inhalation exposure to 1,3-butadiene. Toxicol Sci (2010) 0.95
Mitochondrial toxicity in fetal Erythrocebus patas monkeys exposed transplacentally to zidovudine plus lamivudine. AIDS Res Hum Retroviruses (2004) 0.95
Transplacentally exposed human and monkey newborn infants show similar evidence of nucleoside reverse transcriptase inhibitor-induced mitochondrial toxicity. Environ Mol Mutagen (2007) 0.93
N-terminal globin adducts as biomarkers for formation of butadiene derived epoxides. Chem Biol Interact (2006) 0.92
Polycyclic aromatic hydrocarbon-DNA adducts in cervix of women infected with carcinogenic human papillomavirus types: an immunohistochemistry study. Mutat Res (2007) 0.90
Low-dose radiation and genotoxic chemicals can protect against stochastic biological effects. Nonlinearity Biol Toxicol Med (2004) 0.89
In utero exposure of female CD-1 mice to AZT and/or 3TC: II. Persistence of functional alterations in cardiac tissue. Cardiovasc Toxicol (2010) 0.89
Column switching HPLC-ESI(+)-MS/MS methods for quantitative analysis of exocyclic dA adducts in the DNA of laboratory animals exposed to 1,3-butadiene. Chem Res Toxicol (2010) 0.87
Persistence of mitochondrial toxicity in hearts of female B6C3F1 mice exposed in utero to 3'-azido-3'-deoxythymidine. Cardiovasc Toxicol (2004) 0.86
Mutagenicity of stereochemical configurations of 1,2-epoxybutene and 1,2:3,4-diepoxybutane in human lymphblastoid cells. Chem Biol Interact (2006) 0.86
In utero exposure of female CD-1 Mice to AZT and/or 3TC: I. Persistence of microscopic lesions in cardiac tissue. Cardiovasc Toxicol (2010) 0.86
Centrosome amplification induced by the antiretroviral nucleoside reverse transcriptase inhibitors lamivudine, stavudine, and didanosine. Environ Mol Mutagen (2009) 0.86
V(D)J recombinase-mediated processing of coding junctions at cryptic recombination signal sequences in peripheral T cells during human development. J Immunol (2006) 0.84
Plasma and cellular markers of 3'-azido-3'-dideoxythymidine (AZT) metabolism as indicators of DNA damage in cord blood mononuclear cells from infants receiving prepartum NRTIs. Environ Mol Mutagen (2007) 0.83
Assessment of multiple types of DNA damage in human placentas from smoking and nonsmoking women in the Czech Republic. Environ Mol Mutagen (2011) 0.82
WR1065 mitigates AZT-ddI-induced mutagenesis and inhibits viral replication. Environ Mol Mutagen (2009) 0.81
Mutational analysis of the mitochondrial tRNA genes and flanking regions in umbilical cord tissue from uninfected infants receiving AZT-based therapies for prophylaxis of HIV-1. Environ Mol Mutagen (2009) 0.81
Molecular analysis of mutations at the HPRT and TK loci of human lymphoblastoid cells after combined treatments with 3'-azido-3'-deoxythymidine and 2',3'-dideoxyinosinedagger. Environ Mol Mutagen (2002) 0.80
Characterization of Hprt mutations in cDNA and genomic DNA of T-cell mutants from control and 1,3-butadiene-exposed male B6C3F1 mice and F344 rats. Environ Mol Mutagen (2004) 0.80
Age-, gender-, and species-dependent mutagenicity in T cells of mice and rats exposed by inhalation to 1,3-butadiene. Chem Biol Interact (2006) 0.80
Transcriptional signatures of normal human mammary epithelial cells in response to benzo[a]pyrene exposure: a comparison of three microarray platforms. OMICS (2005) 0.80
VDJ recombinase-mediated TCR β locus gene usage and coding joint processing in peripheral T cells during perinatal and pediatric development. J Immunol (2012) 0.80
Tamoxifen induces expression of immune response-related genes in cultured normal human mammary epithelial cells. Cancer Res (2009) 0.80
Evaluation of effects from repeated inhalation exposure of F344 rats to high concentrations of propylene. Toxicol Sci (2007) 0.79
Genotoxicity of 1,3-butadiene and its epoxy intermediates. Res Rep Health Eff Inst (2009) 0.78
Mutagenicity of stereochemical configurations of 1,3-butadiene epoxy metabolites in human cells. Res Rep Health Eff Inst (2010) 0.78
Cisplatin-DNA damage in p21WAF1/Cip1 deficient mouse keratinocytes exposed to cisplatin. Mutagenesis (2006) 0.77
The stress response resolution assay. II. Quantitative assessment of environmental agent/condition effects on cellular stress resolution outcomes in epithelium. Environ Mol Mutagen (2013) 0.77
Benzo[a]pyrene (BP) DNA adduct formation in DNA repair-deficient p53 haploinsufficient [Xpa(-/-)p53(+/-)] and wild-type mice fed BP and BP plus chlorophyllin for 28 days. Carcinogenesis (2012) 0.76
The importance of 3,4-epoxy-1,2-butanediol and hydroxymethylvinyl ketone in 3-butene-1,2-diol associated mutagenicity. Chem Biol Interact (2007) 0.76
Antiretroviral activity of the aminothiol WR1065 against Human Immunodeficiency virus (HIV-1) in vitro and Simian Immunodeficiency virus (SIV) ex vivo. AIDS Res Ther (2009) 0.75
Hprt mutant frequency and p53 gene status in mice chronically exposed by inhalation to benzene. Chem Biol Interact (2009) 0.75
Measurement of plasma or urinary metabolites and Hprt mutant frequencies following inhalation exposure of mice and rats to 3-butene-1,2-diol. Chem Biol Interact (2007) 0.75
Hprt mutant frequencies in splenic T-cells of male F344 rats exposed by inhalation to propylene. Environ Mol Mutagen (2004) 0.75
Role of nucleotide excision repair and p53 in zidovudine (AZT)-induced centrosomal deregulation. Environ Mol Mutagen (2014) 0.75
The stress response resolution assay. I. Quantitative assessment of environmental agent/condition effects on cellular stress resolution outcomes in epithelium. Environ Mol Mutagen (2013) 0.75