Published in Mol Pharmacol on September 01, 2004
Development of Antioxidant COX-2 Inhibitors as Radioprotective Agents for Radiation Therapy-A Hypothesis-Driven Review. Antioxidants (Basel) (2016) 0.76
Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy (2012) 20.08
HMGB1, a novel cytokine-like mediator linking acute neuronal death and delayed neuroinflammation in the postischemic brain. J Neurosci (2006) 2.68
Repression of alpha-synuclein expression and toxicity by microRNA-7. Proc Natl Acad Sci U S A (2009) 2.61
BTB domain-containing speckle-type POZ protein (SPOP) serves as an adaptor of Daxx for ubiquitination by Cul3-based ubiquitin ligase. J Biol Chem (2006) 2.03
Aberrant epigenetic modifications in hepatocarcinogenesis induced by hepatitis B virus X protein. Gastroenterology (2007) 1.68
Nestin is required for the proper self-renewal of neural stem cells. Stem Cells (2010) 1.62
Induction and subcellular localization of high-mobility group box-1 (HMGB1) in the postischemic rat brain. J Neurosci Res (2008) 1.54
Plexin-A2 and its ligand, Sema6A, control nucleus-centrosome coupling in migrating granule cells. Nat Neurosci (2008) 1.44
Enhanced transfection efficiency of PAMAM dendrimer by surface modification with L-arginine. J Control Release (2004) 1.43
Astaxanthin inhibits nitric oxide production and inflammatory gene expression by suppressing I(kappa)B kinase-dependent NF-kappaB activation. Mol Cells (2003) 1.40
DNA looping-mediated repression by histone-like protein H-NS: specific requirement of Esigma70 as a cofactor for looping. Genes Dev (2005) 1.38
Behavioral stress accelerates plaque pathogenesis in the brain of Tg2576 mice via generation of metabolic oxidative stress. J Neurochem (2008) 1.36
Optimization of chronic stress paradigms using anxiety- and depression-like behavioral parameters. J Neurosci Res (2006) 1.34
Inhibition of the cerebral ischemic injury by ethyl pyruvate with a wide therapeutic window. Stroke (2005) 1.32
Adenylyl cyclase type 5 (AC5) is an essential mediator of morphine action. Proc Natl Acad Sci U S A (2006) 1.28
Mechanisms underlying TGF-beta1-induced expression of VEGF and Flk-1 in mouse macrophages and their implications for angiogenesis. J Leukoc Biol (2006) 1.28
Fractalkine stimulates angiogenesis by activating the Raf-1/MEK/ERK- and PI3K/Akt/eNOS-dependent signal pathways. Am J Physiol Heart Circ Physiol (2006) 1.28
Glycyrrhizic acid affords robust neuroprotection in the postischemic brain via anti-inflammatory effect by inhibiting HMGB1 phosphorylation and secretion. Neurobiol Dis (2012) 1.27
Impaired D2 dopamine receptor function in mice lacking type 5 adenylyl cyclase. J Neurosci (2002) 1.26
Administration of the p38 MAPK inhibitor SB203580 affords brain protection with a wide therapeutic window against focal ischemic insult. J Neurosci Res (2003) 1.22
DJ-1 induces thioredoxin 1 expression through the Nrf2 pathway. Hum Mol Genet (2012) 1.22
Basal C-peptide Level as a Surrogate Marker of Subclinical Atherosclerosis in Type 2 Diabetic Patients. Diabetes Metab J (2011) 1.22
Transglutaminase 2: a multi-functional protein in multiple subcellular compartments. Amino Acids (2010) 1.20
Fluoxetine affords robust neuroprotection in the postischemic brain via its anti-inflammatory effect. J Neurosci Res (2009) 1.20
The non-provitamin A carotenoid, lutein, inhibits NF-kappaB-dependent gene expression through redox-based regulation of the phosphatidylinositol 3-kinase/PTEN/Akt and NF-kappaB-inducing kinase pathways: role of H(2)O(2) in NF-kappaB activation. Free Radic Biol Med (2008) 1.19
Icariin stimulates angiogenesis by activating the MEK/ERK- and PI3K/Akt/eNOS-dependent signal pathways in human endothelial cells. Biochem Biophys Res Commun (2008) 1.19
Immunoproteomics profiling of blood stage Plasmodium vivax infection by high-throughput screening assays. J Proteome Res (2010) 1.18
14-3-3epsilon inhibits MK5-mediated cell migration by disrupting F-actin polymerization. Cell Signal (2007) 1.16
DJ-1 protects against oxidative damage by regulating the thioredoxin/ASK1 complex. Neurosci Res (2010) 1.10
Extracellular HMGB1 released by NMDA treatment confers neuronal apoptosis via RAGE-p38 MAPK/ERK signaling pathway. Neurotox Res (2010) 1.10
Notch interferes with the scaffold function of JNK-interacting protein 1 to inhibit the JNK signaling pathway. Proc Natl Acad Sci U S A (2005) 1.08
Carbon monoxide promotes VEGF expression by increasing HIF-1alpha protein level via two distinct mechanisms, translational activation and stabilization of HIF-1alpha protein. J Biol Chem (2010) 1.07
Water extract of Korean red ginseng stimulates angiogenesis by activating the PI3K/Akt-dependent ERK1/2 and eNOS pathways in human umbilical vein endothelial cells. Biol Pharm Bull (2007) 1.07
NADPH oxidase mediates depressive behavior induced by chronic stress in mice. J Neurosci (2012) 1.07
beta-Carotene inhibits inflammatory gene expression in lipopolysaccharide-stimulated macrophages by suppressing redox-based NF-kappaB activation. Exp Mol Med (2005) 1.07
Concave microwell based size-controllable hepatosphere as a three-dimensional liver tissue model. Biomaterials (2011) 1.06
The flavonoid ellagic acid from a medicinal herb inhibits host immune tolerance induced by the hepatitis B virus-e antigen. Antiviral Res (2006) 1.06
alphaB-crystallin suppresses oxidative stress-induced astrocyte apoptosis by inhibiting caspase-3 activation. Neurosci Res (2009) 1.05
Progressive cognitive impairment and anxiety induction in the absence of plaque deposition in C57BL/6 inbred mice expressing transgenic amyloid precursor protein. J Neurosci Res (2004) 1.05
Intranasal delivery of HMGB1 siRNA confers target gene knockdown and robust neuroprotection in the postischemic brain. Mol Ther (2012) 1.05
Expression of wild-type and truncated myocilins in trabecular meshwork cells: their subcellular localizations and cytotoxicities. Invest Ophthalmol Vis Sci (2002) 1.04
Fluoxetine attenuates kainic acid-induced neuronal cell death in the mouse hippocampus. Brain Res (2009) 1.03
Deregulation of DNA methyltransferases and loss of parental methylation at the insulin-like growth factor II (Igf2)/H19 loci in p53 knockout mice prior to tumor development. J Cell Biochem (2005) 1.03
Anti-inflammatory mechanism is involved in ethyl pyruvate-mediated efficacious neuroprotection in the postischemic brain. Brain Res (2005) 1.02
Clinical analysis of right anterior segmentectomy for hepatic malignancy. Hepatogastroenterology (2006) 1.02
Progressive neuronal loss and behavioral impairments of transgenic C57BL/6 inbred mice expressing the carboxy terminus of amyloid precursor protein. Neurobiol Dis (2005) 1.01
COX-2 regulates p53 activity and inhibits DNA damage-induced apoptosis. Biochem Biophys Res Commun (2005) 1.01
Trichostatin A, a histone deacetylase inhibitor, activates the IGFBP-3 promoter by upregulating Sp1 activity in hepatoma cells: alteration of the Sp1/Sp3/HDAC1 multiprotein complex. Biochem Biophys Res Commun (2002) 0.99
Neuroprotection by biodegradable PAMAM ester (e-PAM-R)-mediated HMGB1 siRNA delivery in primary cortical cultures and in the postischemic brain. J Control Release (2009) 0.99
Forskolin increases angiogenesis through the coordinated cross-talk of PKA-dependent VEGF expression and Epac-mediated PI3K/Akt/eNOS signaling. Cell Signal (2009) 0.98
Repression of tau hyperphosphorylation by chronic endurance exercise in aged transgenic mouse model of tauopathies. J Neurosci Res (2009) 0.98
Mice lacking adenylyl cyclase-5 cope badly with repeated restraint stress. J Neurosci Res (2009) 0.97
Repression of phospho-JNK and infarct volume in ischemic brain of JIP1-deficient mice. J Neurosci Res (2003) 0.97
New insights into the mechanisms for photodynamic therapy-induced cancer cell death. Int Rev Cell Mol Biol (2012) 0.97
Adenylyl cyclase-5 activity in the nucleus accumbens regulates anxiety-related behavior. J Neurochem (2008) 0.97
Cyclooxygenase-2-dependent neuronal death proceeds via superoxide anion generation. Free Radic Biol Med (2006) 0.97
Ethyl pyruvate attenuates kainic acid-induced neuronal cell death in the mouse hippocampus. J Neurosci Res (2006) 0.96
Delayed genomic responses to transient middle cerebral artery occlusion in the rat. J Neurochem (2004) 0.96
Glucosamine exerts a neuroprotective effect via suppression of inflammation in rat brain ischemia/reperfusion injury. Glia (2010) 0.96
Loss of beta-cells with fibrotic islet destruction in type 2 diabetes mellitus. Front Biosci (2008) 0.95
Exendin-4 protects oxidative stress-induced β-cell apoptosis through reduced JNK and GSK3β activity. J Korean Med Sci (2010) 0.95
Pv12, a 6-Cys antigen of Plasmodium vivax, is localized to the merozoite rhoptry. Parasitol Int (2012) 0.95
Tetraspanin CD151 stimulates adhesion-dependent activation of Ras, Rac, and Cdc42 by facilitating molecular association between β1 integrins and small GTPases. J Biol Chem (2012) 0.95
An update of animal models of Alzheimer disease with a reevaluation of plaque depositions. Exp Neurobiol (2013) 0.95
Up-down regulation of HO-1 and iNOS gene expressions by ethyl pyruvate via recruiting p300 to Nrf2 and depriving It from p65. Free Radic Biol Med (2013) 0.94
Cleavage of 14-3-3 protein by caspase-3 facilitates bad interaction with Bcl-x(L) during apoptosis. J Biol Chem (2003) 0.94
C-peptide activates AMPKα and prevents ROS-mediated mitochondrial fission and endothelial apoptosis in diabetes. Diabetes (2013) 0.94
Calcium-sensitive adenylyl cyclases in depression and anxiety: behavioral and biochemical consequences of isoform targeting. Biol Psychiatry (2008) 0.94
Mice lacking adenylyl cyclase type 5 (AC5) show increased ethanol consumption and reduced ethanol sensitivity. Psychopharmacology (Berl) (2010) 0.93
Interaction of HCV core protein with 14-3-3epsilon protein releases Bax to activate apoptosis. Biochem Biophys Res Commun (2006) 0.93