Published in Carcinogenesis on September 09, 2004
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N-3 Polyunsaturated Fatty Acids (PUFAs) Reverse the Impact of Early-Life Stress on the Gut Microbiota. PLoS One (2015) 1.46
Omega-3 polyunsaturated fatty acids inhibit hepatocellular carcinoma cell growth through blocking beta-catenin and cyclooxygenase-2. Mol Cancer Ther (2009) 1.31
The omega-3 polyunsaturated fatty acid DHA induces simultaneous apoptosis and autophagy via mitochondrial ROS-mediated Akt-mTOR signaling in prostate cancer cells expressing mutant p53. Biomed Res Int (2013) 1.07
Intake of polyunsaturated fatty acids and distal large bowel cancer risk in whites and African Americans. Am J Epidemiol (2010) 1.05
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Omega-3 fatty acids and the regulation of expression of endothelial pro-atherogenic and pro-inflammatory genes. J Membr Biol (2005) 0.98
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Association of cancer metabolism-related proteins with oral carcinogenesis - indications for chemoprevention and metabolic sensitizing of oral squamous cell carcinoma? J Transl Med (2014) 0.92
Exosome-mediated microRNA signaling from breast cancer cells is altered by the anti-angiogenesis agent docosahexaenoic acid (DHA). Mol Cancer (2015) 0.91
The Antitumor Effects of Triterpenoid Saponins from the Anemone flaccida and the Underlying Mechanism. Evid Based Complement Alternat Med (2013) 0.91
Omega-3 eicosapentaenoic acid decreases CD133 colon cancer stem-like cell marker expression while increasing sensitivity to chemotherapy. PLoS One (2013) 0.90
Experimental evidence of ω-3 polyunsaturated fatty acid modulation of inflammatory cytokines and bioactive lipid mediators: their potential role in inflammatory, neurodegenerative, and neoplastic diseases. Biomed Res Int (2013) 0.89
Gamma-linolenic acid inhibits both tumour cell cycle progression and angiogenesis in the orthotopic C6 glioma model through changes in VEGF, Flt1, ERK1/2, MMP2, cyclin D1, pRb, p53 and p27 protein expression. Lipids Health Dis (2009) 0.89
Long-chain omega-3 polyunsaturated fatty acid intake and risk of colorectal cancer. Nutr Cancer (2013) 0.88
The omega-3 polyunsaturated fatty acid eicosapentaenoic acid inhibits mouse MC-26 colorectal cancer cell liver metastasis via inhibition of PGE2-dependent cell motility. Br J Pharmacol (2012) 0.88
The {omega}-3 fatty acid eicosapentaenoic acid elicits cAMP generation in colonic epithelial cells via a "store-operated" mechanism. Am J Physiol Gastrointest Liver Physiol (2010) 0.87
Matrix metalloproteinase (MMP)-9 in cancer-associated fibroblasts (CAFs) is suppressed by omega-3 polyunsaturated fatty acids in vitro and in vivo. PLoS One (2014) 0.86
Omega-3 polyunsaturated fatty acids selectively inhibit growth in neoplastic oral keratinocytes by differentially activating ERK1/2. Carcinogenesis (2013) 0.85
Inhibition of colon cancer growth by docosahexaenoic acid involves autocrine production of TNFα. Oncogene (2016) 0.85
Endogenously generated omega-3 fatty acids attenuate vascular inflammation and neointimal hyperplasia by interaction with free fatty acid receptor 4 in mice. J Am Heart Assoc (2015) 0.84
Omega-3 Fatty Acids in Modern Parenteral Nutrition: A Review of the Current Evidence. J Clin Med (2016) 0.82
Omega-3 fatty acid is a potential preventive agent for recurrent colon cancer. Cancer Prev Res (Phila) (2014) 0.81
Impact of EPA ingestion on COX- and LOX-mediated eicosanoid synthesis in skin with and without a pro-inflammatory UVR challenge--report of a randomised controlled study in humans. Mol Nutr Food Res (2013) 0.81
The multifaceted effects of omega-3 polyunsaturated Fatty acids on the hallmarks of cancer. J Lipids (2013) 0.81
Coexpression of COX-2 and iNOS in Angiogenesis of Superficial Esophageal Squamous Cell Carcinoma. Int Surg (2015) 0.80
Expression and significance of factors related to angiogenesis in choroidal melanoma. Int J Ophthalmol (2011) 0.80
Potential role of polyunsaturated fatty acids in diabetic retinopathy. Arch Med Sci (2014) 0.80
Prostaglandin E3 metabolism and cancer. Cancer Lett (2014) 0.80
Fatty acids in habitual diet, plasma phospholipids, and tumour and normal colonic biopsies in young colorectal cancer patients. J Oncol (2012) 0.79
Eicosapentaenoic acid (EPA) efficacy for colorectal aberrant crypt foci (ACF): a double-blind randomized controlled trial. BMC Cancer (2012) 0.78
ω3 Polyunsaturated Fatty Acids as Immunomodulators in Colorectal Cancer: New Potential Role in Adjuvant Therapies. Front Immunol (2016) 0.77
Dietary derived compounds in cancer chemoprevention. Contemp Oncol (Pozn) (2012) 0.77
Docosahexaenoic acid suppresses arachidonic acid-induced proliferation of LS-174T human colon carcinoma cells. World J Gastroenterol (2009) 0.77
G-protein-coupled receptors mediate ω-3 PUFAs-inhibited colorectal cancer by activating the Hippo pathway. Oncotarget (2016) 0.75
Diabetic macular edema, retinopathy and age-related macular degeneration as inflammatory conditions. Arch Med Sci (2016) 0.75
Involvement of plasmalogens in post-natal retinal vascular development. PLoS One (2014) 0.75
Docosahexaenoic Acid Inhibits Tumor Promoter-Induced Urokinase-Type Plasminogen Activator Receptor by Suppressing PKCδ- and MAPKs-Mediated Pathways in ECV304 Human Endothelial Cells. PLoS One (2016) 0.75
The role of small intestinal bacterial overgrowth in Parkinson's disease. Mov Disord (2013) 1.62
Dilated intercellular spaces of esophageal epithelium in nonerosive reflux disease patients with physiological esophageal acid exposure. Am J Gastroenterol (2005) 1.60
Role of p16/INK4a in gastrointestinal stromal tumor progression. Am J Clin Pathol (2004) 1.54
Retracted Lycopene inhibits NF-kB-mediated IL-8 expression and changes redox and PPARγ signalling in cigarette smoke-stimulated macrophages. PLoS One (2011) 1.52
Synergistic inhibitory activities of interleukin-10 and dexamethasone on human CD4+ T cells. Transplantation (2002) 1.40
Cyclooxygenase-2 expression is induced during human megakaryopoiesis and characterizes newly formed platelets. Proc Natl Acad Sci U S A (2002) 1.39
Proinflammatory-activated trigeminal satellite cells promote neuronal sensitization: relevance for migraine pathology. Mol Pain (2009) 1.24
Intravesical electromotive mitomycin C versus passive transport mitomycin C for high risk superficial bladder cancer: a prospective randomized study. J Urol (2003) 1.22
Erythropoietin exerts anti-apoptotic effects on rat microglial cells in vitro. Eur J Neurosci (2002) 1.20
Ipilimumab: a novel immunostimulatory monoclonal antibody for the treatment of cancer. Pharmacol Res (2011) 1.18
Involvement of mTOR kinase in cytokine-dependent microglial activation and cell proliferation. Biochem Pharmacol (2009) 1.17
Role of the life span determinant P66(shcA) in ethanol-induced liver damage. Lab Invest (2008) 1.15
Pharmacokinetic variability of antiretroviral drugs and correlation with virological outcome: 2 years of experience in routine clinical practice. J Antimicrob Chemother (2009) 1.12
Docosahexaenoic acid induces apoptosis in lung cancer cells by increasing MKP-1 and down-regulating p-ERK1/2 and p-p38 expression. Apoptosis (2008) 1.10
Abrogation of hepatocyte apoptosis and early appearance of liver dysplasia in ethanol-fed p53-deficient mice. Biochem Biophys Res Commun (2004) 1.07
The mTOR kinase inhibitor rapamycin decreases iNOS mRNA stability in astrocytes. J Neuroinflammation (2011) 1.05
Dietary polyunsaturated fatty acids as inducers of apoptosis: implications for cancer. Apoptosis (2009) 1.04
Docosahexaenoic acid induces proteasome-dependent degradation of beta-catenin, down-regulation of survivin and apoptosis in human colorectal cancer cells not expressing COX-2. Carcinogenesis (2006) 1.03
mTOR kinase, a key player in the regulation of glial functions: relevance for the therapy of multiple sclerosis. Glia (2012) 1.02
Electrophysiological and molecular evidence of L-(Cav1), N- (Cav2.2), and R- (Cav2.3) type Ca2+ channels in rat cortical astrocytes. Glia (2004) 1.01
The integrin antagonist cilengitide increases the antitumor activity of temozolomide against malignant melanoma. Oncol Rep (2008) 0.98
Lycopene induces cell growth inhibition by altering mevalonate pathway and Ras signaling in cancer cell lines. Carcinogenesis (2010) 0.98
Cyclooxygenase-2 expression in endometrial carcinoma: correlation with clinicopathologic parameters and clinical outcome. Cancer (2002) 0.98
Lactobacillus acidophilus protects tight junctions from aspirin damage in HT-29 cells. Digestion (2004) 0.98
Resistin regulates human choriocarcinoma cell invasive behaviour and endothelial cell angiogenic processes. J Endocrinol (2006) 0.97
DHA induces apoptosis by altering the expression and cellular location of GRP78 in colon cancer cell lines. Biochim Biophys Acta (2012) 0.96
Novel sensitive, specific and rapid pharmacogenomic test for the prediction of abacavir hypersensitivity reaction: HLA-B*57:01 detection by real-time PCR. Pharmacogenomics (2011) 0.94
Anti-tissue transglutaminase antibodies from celiac patients are responsible for trophoblast damage via apoptosis in vitro. Am J Gastroenterol (2010) 0.94
Antioxidant protection against acoustic trauma by coadministration of idebenone and vitamin E. Neuroreport (2008) 0.93
Prooxidant effects of beta-carotene in cultured cells. Mol Aspects Med (2003) 0.93
Celecoxib modulates the expression of cyclooxygenase-2, ki67, apoptosis-related marker, and microvessel density in human cervical cancer: a pilot study. Clin Cancer Res (2003) 0.93
Infliximab therapy inhibits inflammation-induced angiogenesis in the mucosa of patients with Crohn's disease. Am J Gastroenterol (2011) 0.92
CRH inhibits cell growth of human endometrial adenocarcinoma cells via CRH-receptor 1-mediated activation of cAMP-PKA pathway. Endocrinology (2002) 0.91
beta-Carotene exacerbates DNA oxidative damage and modifies p53-related pathways of cell proliferation and apoptosis in cultured cells exposed to tobacco smoke condensate. Carcinogenesis (2004) 0.91
Lycopene prevention of oxysterol-induced proinflammatory cytokine cascade in human macrophages: inhibition of NF-κB nuclear binding and increase in PPARγ expression. J Nutr Biochem (2010) 0.91
DNA damage and apoptosis induction by the pesticide Mancozeb in rat cells: involvement of the oxidative mechanism. Toxicol Appl Pharmacol (2005) 0.91
Valproic acid activity in androgen-sensitive and -insensitive human prostate cancer cells. Int J Oncol (2008) 0.90
Stable depletion of poly (ADP-ribose) polymerase-1 reduces in vivo melanoma growth and increases chemosensitivity. Eur J Cancer (2008) 0.90
Regulation of magnesium content during proliferation of mammary epithelial cells (HC-11). Front Biosci (2004) 0.90
Docosahexaenoic acid enhances the susceptibility of human colorectal cancer cells to 5-fluorouracil. Cancer Chemother Pharmacol (2004) 0.90
Experimental evidence of ω-3 polyunsaturated fatty acid modulation of inflammatory cytokines and bioactive lipid mediators: their potential role in inflammatory, neurodegenerative, and neoplastic diseases. Biomed Res Int (2013) 0.89
Docosahexaenoic acid reverts resistance to UV-induced apoptosis in human keratinocytes: involvement of COX-2 and HuR. J Nutr Biochem (2010) 0.89
Frequent loss of expression of the cyclin-dependent kinase inhibitor p27(Kip1) in estrogen-related Endometrial adenocarcinomas. Clin Cancer Res (2003) 0.89
Immunohistochemical analysis of ZO-1 in the duodenal mucosa of patients with untreated and treated celiac disease. Digestion (2002) 0.89
Protective properties of idebenone in noise-induced hearing loss in the guinea pig. Neuroreport (2006) 0.89
Evidence that corticotropin-releasing hormone inhibits cell growth of human breast cancer cells via the activation of CRH-R1 receptor subtype. Mol Cell Endocrinol (2006) 0.89
Lycopene prevents 7-ketocholesterol-induced oxidative stress, cell cycle arrest and apoptosis in human macrophages. J Nutr Biochem (2009) 0.89
Dietary n-3 polyunsaturated fatty acids and the paradox of their health benefits and potential harmful effects. Chem Res Toxicol (2011) 0.88
Homocysteine induces trophoblast cell death with apoptotic features. Biol Reprod (2003) 0.88
Modulation of apoptotic signalling by carotenoids in cancer cells. Arch Biochem Biophys (2004) 0.88
Poly(ADP-ribose) polymerase inhibitor increases growth inhibition and reduces G(2)/M cell accumulation induced by temozolomide in malignant glioma cells. Glia (2002) 0.87
Cyclo-oxygenase-2 (Cox-2) expression and resistance to platinum versus platinum/paclitaxel containing chemotherapy in advanced ovarian cancer. BMC Cancer (2006) 0.87
Role of PTEN in gastrointestinal stromal tumor progression. Arch Pathol Lab Med (2004) 0.87
Lycopene regulation of cholesterol synthesis and efflux in human macrophages. J Nutr Biochem (2011) 0.87
Comparative antioxidant activity of tocotrienols and the novel chromanyl-polyisoprenyl molecule FeAox-6 in isolated membranes and intact cells. Mol Cell Biochem (2006) 0.87
Expression and activity of cyclooxygenase isoforms in skeletal muscles and myocardium of humans and rodents. J Appl Physiol (1985) (2007) 0.87
IgA nephropathy in an Italian child with familial Mediterranean fever. Pediatr Nephrol (2005) 0.86
Antibodies anti-CagA cross-react with trophoblast cells: a risk factor for pre-eclampsia? Helicobacter (2012) 0.86
Constitutive and inducible expression of the epithelial antigen MUC1 (CD227) in human T cells. Exp Cell Res (2002) 0.86
DHA induces apoptosis and differentiation in human melanoma cells in vitro: involvement of HuR-mediated COX-2 mRNA stabilization and β-catenin nuclear translocation. Carcinogenesis (2011) 0.86
Repeated exposure to pyrrolidine-dithiocarbamate induces peripheral nerve alterations in rats. Toxicol Lett (2005) 0.86
Mechanism of activation of caspase cascade during beta-carotene-induced apoptosis in human tumor cells. Nutr Cancer (2003) 0.86