Published in Circulation on September 14, 2004
The role of adipose tissue and adipokines in obesity-related inflammatory diseases. Mediators Inflamm (2010) 1.59
In vivo genetic profiling and cellular localization of apelin reveals a hypoxia-sensitive, endothelial-centered pathway activated in ischemic heart failure. Am J Physiol Heart Circ Physiol (2007) 1.54
Endogenous regulation of cardiovascular function by apelin-APJ. Am J Physiol Heart Circ Physiol (2009) 1.34
Sepsis-induced cardiomyopathy. Curr Cardiol Rev (2011) 1.21
Apelin prevents aortic aneurysm formation by inhibiting macrophage inflammation. Am J Physiol Heart Circ Physiol (2009) 1.19
ERG-APLNR axis controls pulmonary venule endothelial proliferation in pulmonary veno-occlusive disease. Circulation (2014) 1.18
Loss of Apelin exacerbates myocardial infarction adverse remodeling and ischemia-reperfusion injury: therapeutic potential of synthetic Apelin analogues. J Am Heart Assoc (2013) 1.05
Estradiol improves right ventricular function in rats with severe angioproliferative pulmonary hypertension: effects of endogenous and exogenous sex hormones. Am J Physiol Lung Cell Mol Physiol (2015) 1.02
Apelin protects against angiotensin II-induced cardiovascular fibrosis and decreases plasminogen activator inhibitor type-1 production. J Hypertens (2011) 1.00
HIF-1 regulates hypoxia- and insulin-induced expression of apelin in adipocytes. Am J Physiol Endocrinol Metab (2007) 1.00
Apelin increases cardiac contractility via protein kinase Cε- and extracellular signal-regulated kinase-dependent mechanisms. PLoS One (2014) 0.97
Apelin is a positive regulator of ACE2 in failing hearts. J Clin Invest (2013) 0.95
Apelin increases contractility in failing cardiac muscle. Eur J Pharmacol (2006) 0.94
Reciprocal regulation of plasma apelin and vasopressin by osmotic stimuli. J Am Soc Nephrol (2008) 0.93
Apelin, Elabela/Toddler, and biased agonists as novel therapeutic agents in the cardiovascular system. Trends Pharmacol Sci (2015) 0.91
Central and peripheral apelin receptor distribution in the mouse: species differences with rat. Peptides (2011) 0.87
By interacting with the C-terminal Phe of apelin, Phe255 and Trp259 in helix VI of the apelin receptor are critical for internalization. J Biol Chem (2010) 0.87
Apelin and pulmonary hypertension. Pulm Circ (2011) 0.86
Apelin: a novel marker for the patients with first ST-elevation myocardial infarction. Heart Vessels (2010) 0.86
Design, characterization, and first-in-human study of the vascular actions of a novel biased apelin receptor agonist. Hypertension (2015) 0.85
Biased signaling favoring gi over β-arrestin promoted by an apelin fragment lacking the C-terminal phenylalanine. J Biol Chem (2014) 0.84
Postnatal overfeeding causes early shifts in gene expression in the heart and long-term alterations in cardiometabolic and oxidative parameters. PLoS One (2013) 0.84
Serum apelin level predicts the major adverse cardiac events in patients with ST elevation myocardial infarction receiving percutaneous coronary intervention. Medicine (Baltimore) (2015) 0.79
Effects of acute intravenous infusion of apelin on left ventricular function in dogs with advanced heart failure. J Card Fail (2013) 0.79
Modulation of canine cardiac sodium current by Apelin. J Mol Cell Cardiol (2009) 0.79
Targeting the ACE2 and Apelin Pathways Are Novel Therapies for Heart Failure: Opportunities and Challenges. Cardiol Res Pract (2012) 0.79
Investigating interactions between epicardial adipose tissue and cardiac myocytes: what can we learn from different approaches? Br J Pharmacol (2016) 0.78
Apelin as a marker for monitoring the tumor vessel normalization window during antiangiogenic therapy. Cancer Sci (2015) 0.78
Pressor effect of apelin-13 in the rostral ventrolateral medulla: role of NAD(P)H oxidase-derived superoxide. J Pharmacol Exp Ther (2010) 0.78
Effects of apelin on the cardiovascular system. Heart Fail Rev (2015) 0.77
Cardiac action of the first G protein biased small molecule apelin agonist. Biochem Pharmacol (2016) 0.77
Apelin and vascular endothelial growth factor are associated with mobilization of endothelial progenitor cells after acute myocardial infarction. J Biomed Res (2012) 0.76
APpEaLINg therapeutic target for obesity cardiomyopathy? J Mol Cell Cardiol (2013) 0.75
Apelin receptor (APJ) expression during cardiopulmonary bypass in children undergoing surgical repair. PLoS One (2014) 0.75
Why don't they beat?: Cripto, apelin/APJ, and myocardial differentiation. Circ Res (2009) 0.75
Co-administration of Apelin and T4 Protects Inotropic and Chronotropic Changes Occurring in Hypothyroid Rats. Arq Bras Cardiol (2015) 0.75
G-protein Coupled Receptor Signaling in Pluripotent Stem Cell-derived Cardiovascular Cells: Implications for Disease Modeling. Front Cell Dev Biol (2015) 0.75
The Apelin-APJ System in the Evolution of Heart Failure. Clujul Med (2015) 0.75
Forecasting the future of cardiovascular disease in the United States: a policy statement from the American Heart Association. Circulation (2011) 14.00
2013 ACCF/AHA guideline for the management of ST-elevation myocardial infarction: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. J Am Coll Cardiol (2012) 7.94
Surgical treatment of moderate ischemic mitral regurgitation. N Engl J Med (2014) 7.23
2013 ACCF/AHA guideline for the management of ST-elevation myocardial infarction: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. Circulation (2012) 6.94
Mitral-valve repair versus replacement for severe ischemic mitral regurgitation. N Engl J Med (2013) 6.21
Surgical ablation of atrial fibrillation during mitral-valve surgery. N Engl J Med (2015) 4.77
Mesenchymal stem cell injection after myocardial infarction improves myocardial compliance. Am J Physiol Heart Circ Physiol (2006) 3.78
An evidence-based review of the practice of cardiopulmonary bypass in adults: a focus on neurologic injury, glycemic control, hemodilution, and the inflammatory response. J Thorac Cardiovasc Surg (2006) 3.09
Fish oil and postoperative atrial fibrillation: the Omega-3 Fatty Acids for Prevention of Post-operative Atrial Fibrillation (OPERA) randomized trial. JAMA (2012) 2.66
2012 ACCF/AATS/SCAI/STS expert consensus document on transcatheter aortic valve replacement. J Am Coll Cardiol (2012) 2.44
Saddle-shape annuloplasty increases mitral leaflet coaptation after repair for flail posterior leaflet. Ann Thorac Surg (2011) 2.42
Effect of blinded peer review on abstract acceptance. JAMA (2006) 2.38
Risk score derived from pre-operative data analysis predicts the need for biventricular mechanical circulatory support. J Heart Lung Transplant (2008) 2.32
Antegrade thoracic stent grafting during repair of acute DeBakey I dissection prevents development of thoracoabdominal aortic aneurysms. Ann Thorac Surg (2009) 1.95
Neovasculogenic therapy to augment perfusion and preserve viability in ischemic cardiomyopathy. Ann Thorac Surg (2006) 1.82
2013 ACCF/AHA guideline for the management of ST-elevation myocardial infarction: executive summary: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. J Am Coll Cardiol (2012) 1.80
Emergency extracorporeal life support for asphyxic status asthmaticus. Respir Care (2007) 1.59
Significance of malperfusion syndromes prior to contemporary surgical repair for acute type A dissection: outcomes and need for additional revascularizations. Eur J Cardiothorac Surg (2007) 1.59
Advances in the treatment of acute type A dissection: an integrated approach. Ann Thorac Surg (2002) 1.52
Transmyocardial revascularization to enhance myocardial vasculogenesis and hemodynamic function. J Thorac Cardiovasc Surg (2008) 1.49
Ascending aortic cannulation in acute type a dissection repair. Ann Thorac Surg (2013) 1.49
Who needs an RVAD in addition to an LVAD? Cardiol Clin (2011) 1.46
Early planned institution of biventricular mechanical circulatory support results in improved outcomes compared with delayed conversion of a left ventricular assist device to a biventricular assist device. J Thorac Cardiovasc Surg (2009) 1.44
Induction of hippocampal long-term potentiation during waking leads to increased extrahippocampal zif-268 expression during ensuing rapid-eye-movement sleep. J Neurosci (2002) 1.44
Left main coronary embolism. J Invasive Cardiol (2006) 1.39
On-pump versus off-pump coronary artery bypass grafting. J Thorac Cardiovasc Surg (2007) 1.37
The American Heart Association's principles for comparative effectiveness research: a policy statement from the American Heart Association. Circulation (2009) 1.33
Neuromuscular control of vocalizations in birdsong: a model. Phys Rev E Stat Nonlin Soft Matter Phys (2002) 1.29
Stromal cell-derived factor-1alpha activation of tissue-engineered endothelial progenitor cell matrix enhances ventricular function after myocardial infarction by inducing neovasculogenesis. Circulation (2010) 1.28
Rescue of dystrophic skeletal muscle by PGC-1α involves a fast to slow fiber type shift in the mdx mouse. PLoS One (2012) 1.26
Fate of the residual distal and proximal aorta after acute type a dissection repair using a contemporary surgical reconstruction algorithm. Ann Thorac Surg (2007) 1.26
Outcomes of the RESTOR-MV Trial (Randomized Evaluation of a Surgical Treatment for Off-Pump Repair of the Mitral Valve). J Am Coll Cardiol (2010) 1.20
Computational protein design to reengineer stromal cell-derived factor-1α generates an effective and translatable angiogenic polypeptide analog. Circulation (2011) 1.20
Stromal cell-derived factor and granulocyte-monocyte colony-stimulating factor form a combined neovasculogenic therapy for ischemic cardiomyopathy. J Thorac Cardiovasc Surg (2005) 1.20
Ethyl pyruvate preserves cardiac function and attenuates oxidative injury after prolonged myocardial ischemia. J Thorac Cardiovasc Surg (2004) 1.19
Optimal surgical management of severe ischemic mitral regurgitation: to repair or to replace? J Thorac Cardiovasc Surg (2011) 1.17
Robot-assisted pharyngeal and laryngeal microsurgery: results of robotic cadaver dissections. Laryngoscope (2005) 1.17
Minimally invasive approach provides at least equivalent results for surgical correction of mitral regurgitation: a propensity-matched comparison. J Thorac Cardiovasc Surg (2013) 1.13
Outcomes using extracorporeal life support for adult respiratory failure due to status asthmaticus. ASAIO J (2009) 1.10
Predicting right ventricular failure in the modern, continuous flow left ventricular assist device era. Ann Thorac Surg (2013) 1.09
Global cardiac-specific transgene expression using cardiopulmonary bypass with cardiac isolation. Ann Thorac Surg (2002) 1.09
Viral gene transfer of the antiapoptotic factor Bcl-2 protects against chronic postischemic heart failure. Circulation (2002) 1.08
Design, rationale, and initiation of the Surgical Interventions for Moderate Ischemic Mitral Regurgitation Trial: a report from the Cardiothoracic Surgical Trials Network. J Thorac Cardiovasc Surg (2011) 1.08
Long-range order in canary song. PLoS Comput Biol (2013) 1.08
Three-dimensional echocardiographic analysis of mitral annular dynamics: implication for annuloplasty selection. Circulation (2012) 1.06
Ischemic heart failure enhances endogenous myocardial apelin and APJ receptor expression. Cell Mol Biol Lett (2006) 1.06
Surgical revision after percutaneous mitral repair with the MitraClip device. Ann Thorac Surg (2010) 1.05
Long-term restoration of cardiac dystrophin expression in golden retriever muscular dystrophy following rAAV6-mediated exon skipping. Mol Ther (2011) 1.05
Blocking the development of postischemic cardiomyopathy with viral gene transfer of the apoptosis repressor with caspase recruitment domain. J Thorac Cardiovasc Surg (2003) 1.05
Robotic microlaryngeal surgery: a technical feasibility study using the daVinci surgical robot and an airway mannequin. Laryngoscope (2005) 1.05
Retrograde and antegrade cerebral perfusion: results in short elective arch reconstructive times. Ann Thorac Surg (2010) 1.04
Induction of angiogenesis and inhibition of apoptosis by hepatocyte growth factor effectively treats postischemic heart failure. J Card Surg (2005) 1.04
Postoperative right ventricular failure after left ventricular assist device placement is predicted by preoperative echocardiographic structural, hemodynamic, and functional parameters. J Card Fail (2013) 1.02
Acute myocardial rescue with endogenous endothelial progenitor cell therapy. Heart Lung Circ (2010) 1.01
A carbon-fiber electrode array for long-term neural recording. J Neural Eng (2013) 0.99
Placental growth factor provides a novel local angiogenic therapy for ischemic cardiomyopathy. J Card Surg (2006) 0.98
Juvenile zebra finches can use multiple strategies to learn the same song. Proc Natl Acad Sci U S A (2004) 0.98
Emergent mechanical support in the community: improvement with early transplant center referral. J Heart Lung Transplant (2005) 0.97
Ventricular assist device implant in the elderly is associated with increased, but respectable risk: a multi-institutional study. Ann Thorac Surg (2013) 0.97
Pro-angiogenic cytokines as cardiovascular therapeutics: assessing the potential. BioDrugs (2008) 0.97
Chronic losartan administration reduces mortality and preserves cardiac but not skeletal muscle function in dystrophic mice. PLoS One (2011) 0.96
Spliced stromal cell-derived factor-1α analog stimulates endothelial progenitor cell migration and improves cardiac function in a dose-dependent manner after myocardial infarction. J Thorac Cardiovasc Surg (2010) 0.95
Inhibition of matrix metalloproteinase activity by TIMP-1 gene transfer effectively treats ischemic cardiomyopathy. Circulation (2004) 0.95
State-of-the-Art Methods for Evaluation of Angiogenesis and Tissue Vascularization: A Scientific Statement From the American Heart Association. Circ Res (2015) 0.94