Published in Hepatology on August 01, 2004
Viral hepatocarcinogenesis. Oncogene (2010) 1.73
Mice with a deletion in the gene for CCAAT/enhancer-binding protein beta are protected against diet-induced obesity. Diabetes (2007) 1.20
Fbxw7 regulates lipid metabolism and cell fate decisions in the mouse liver. J Clin Invest (2010) 1.17
Hepatic metabolism of retinoids and disease associations. Biochim Biophys Acta (2011) 1.13
Rodent models of nonalcoholic fatty liver disease/nonalcoholic steatohepatitis. Int J Mol Sci (2013) 1.04
Liver-specific inducible nitric-oxide synthase expression is sufficient to cause hepatic insulin resistance and mild hyperglycemia in mice. J Biol Chem (2011) 0.97
AEG-1 regulates retinoid X receptor and inhibits retinoid signaling. Cancer Res (2014) 0.93
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Identification of T-cell factor-4 isoforms that contribute to the malignant phenotype of hepatocellular carcinoma cells. Exp Cell Res (2011) 0.89
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Activation of AMP-activated protein kinase by retinoic acid sensitizes hepatocellular carcinoma cells to apoptosis induced by sorafenib. Cancer Sci (2015) 0.83
Multi-SNP analysis of GWAS data identifies pathways associated with nonalcoholic fatty liver disease. PLoS One (2013) 0.82
Vitamin a deficiency and alterations in the extracellular matrix. Nutrients (2014) 0.82
Biological networks for predicting chemical hepatocarcinogenicity using gene expression data from treated mice and relevance across human and rat species. PLoS One (2013) 0.82
Reactive oxygen species and NADPH oxidase 4 induced by transforming growth factor β1 are the therapeutic targets of polyenylphosphatidylcholine in the suppression of human hepatic stellate cell activation. Inflamm Res (2011) 0.81
Acyclic retinoid in chemoprevention of hepatocellular carcinoma: Targeting phosphorylated retinoid X receptor-α for prevention of liver carcinogenesis. J Carcinog (2012) 0.80
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The CD133+CD44+ precancerous subpopulation of oval cells is a therapeutic target for hepatocellular carcinoma. Stem Cells Dev (2014) 0.77
Retinoid and carotenoid status in serum and liver among patients at high-risk for liver cancer. BMC Gastroenterol (2016) 0.76
Retinoid roles in blocking hepatocellular carcinoma. Hepatobiliary Surg Nutr (2015) 0.75
Recent advances in mouse models of obesity- and nonalcoholic steatohepatitis-associated hepatocarcinogenesis. World J Hepatol (2015) 0.75
Biological functional annotation of retinoic acid alpha and beta in mouse liver based on genome-wide binding. Am J Physiol Gastrointest Liver Physiol (2014) 0.75
Impact of Preferentially Expressed Antigen of Melanoma on the Prognosis of Hepatocellular Carcinoma. Gastrointest Tumors (2016) 0.75
Genome-wide association of IL28B with response to pegylated interferon-alpha and ribavirin therapy for chronic hepatitis C. Nat Genet (2009) 14.16
A more efficient method to generate integration-free human iPS cells. Nat Methods (2011) 7.39
Claudin-based tight junctions are crucial for the mammalian epidermal barrier: a lesson from claudin-1-deficient mice. J Cell Biol (2002) 5.51
Autophosphorylation of the DNA-dependent protein kinase catalytic subunit is required for rejoining of DNA double-strand breaks. Genes Dev (2002) 3.83
Characterization of CD133+ hepatocellular carcinoma cells as cancer stem/progenitor cells. Biochem Biophys Res Commun (2006) 3.35
Bone marrow-derived cells express matrix metalloproteinases and contribute to regression of liver fibrosis in mice. Hepatology (2007) 2.34
FibroIndex, a practical index for predicting significant fibrosis in patients with chronic hepatitis C. Hepatology (2007) 2.24
Retinoids ameliorate insulin resistance in a leptin-dependent manner in mice. Hepatology (2012) 2.14
Topical drug rescue strategy and skin protection based on the role of Mc1r in UV-induced tanning. Nature (2006) 2.09
DNA-dependent protein kinase suppresses double-strand break-induced and spontaneous homologous recombination. Proc Natl Acad Sci U S A (2002) 1.92
MicroRNA-143 regulates human osteosarcoma metastasis by regulating matrix metalloprotease-13 expression. Mol Ther (2011) 1.77
Complete absence of Cockayne syndrome group B gene product gives rise to UV-sensitive syndrome but not Cockayne syndrome. Proc Natl Acad Sci U S A (2004) 1.72
Preventive and therapeutic effects of angiotensin II type 1 receptor blocker on hepatic fibrosis induced by bile duct ligation in rats. J Gastroenterol (2006) 1.53
Proteomics-based identification of differentially expressed genes in human gliomas: down-regulation of SIRT2 gene. Biochem Biophys Res Commun (2003) 1.53
Epidermal growth factor plays a crucial role in mitogenic regulation of human brain tumor stem cells. J Biol Chem (2008) 1.52
Quantitative evaluation of night vision and correlation of refractive and topographical parameters with glare after orthokeratology. Graefes Arch Clin Exp Ophthalmol (2011) 1.46
Clomipramine-induced hypersensitivity syndrome with unusual clinical features. J Am Acad Dermatol (2005) 1.45
Genome-wide association study confirming association of HLA-DP with protection against chronic hepatitis B and viral clearance in Japanese and Korean. PLoS One (2012) 1.44
Influence of genotypes and precore mutations on fulminant or chronic outcome of acute hepatitis B virus infection. Hepatology (2006) 1.43
Negative regulation of transforming growth factor-beta (TGF-beta) signaling by WW domain-containing protein 1 (WWP1). Oncogene (2004) 1.42
Mice transgenic for Kit(V620A): recapitulation of piebaldism but not progressive depigmentation seen in humans with this mutation. J Invest Dermatol (2006) 1.40
Late toxicity after definitive concurrent chemoradiotherapy for thoracic esophageal carcinoma. Int J Radiat Oncol Biol Phys (2009) 1.40
Regulation of osteoclast development by Notch signaling directed to osteoclast precursors and through stromal cells. Blood (2002) 1.38
Exo1 plays a major role in DNA end resection in humans and influences double-strand break repair and damage signaling decisions. DNA Repair (Amst) (2012) 1.37
Postoperative radiotherapy for patients with completely resected thymoma: a multi-institutional, retrospective review of 103 patients. Cancer (2002) 1.34
Diffusion-weighted imaging of prostate cancer. J Comput Assist Tomogr (2005) 1.30
High expression of EZH2 is associated with tumor proliferation and prognosis in human oral squamous cell carcinomas. Oral Oncol (2008) 1.29
Treatment and prognosis of squamous cell carcinoma of the external auditory canal and middle ear: a multi-institutional retrospective review of 87 patients. Int J Radiat Oncol Biol Phys (2007) 1.27
VEGF promotes tumorigenesis and angiogenesis of human glioblastoma stem cells. Biochem Biophys Res Commun (2007) 1.20
Warthin tumor of the parotid gland: diagnostic value of MR imaging with histopathologic correlation. AJNR Am J Neuroradiol (2004) 1.19
Dose-dependent roles for canonical Wnt signalling in de novo crypt formation and cell cycle properties of the colonic epithelium. Development (2013) 1.19
SIRT2 down-regulation in HeLa can induce p53 accumulation via p38 MAPK activation-dependent p300 decrease, eventually leading to apoptosis. Genes Cells (2010) 1.19
Myocardial injury in patients with chronic hepatitis C infection. J Hepatol (2012) 1.18
Extranodal natural killer/T-cell lymphoma, nasal type: the significance of radiotherapeutic parameters. Cancer (2006) 1.17
Hepatocyte growth factor exerts a proliferative effect on oval cells through the PI3K/AKT signaling pathway. Biochem Biophys Res Commun (2003) 1.17
Hepatic differentiation of human bone marrow-derived mesenchymal stem cells by tetracycline-regulated hepatocyte nuclear factor 3beta. Hepatology (2008) 1.16
Cell surface biomarkers of embryonic stem cells. Proteomics (2008) 1.14
Diagnostic value of FDG PET and salivary gland scintigraphy for parotid tumors. Clin Nucl Med (2005) 1.14
Percutaneous sonographically guided radiofrequency ablation with artificial pleural effusion for hepatocellular carcinoma located under the diaphragm. AJR Am J Roentgenol (2004) 1.13
Rest promotes the early differentiation of mouse ESCs but is not required for their maintenance. Cell Stem Cell (2010) 1.12
Minichromosome maintenance protein 7 in colorectal cancer: implication of prognostic significance. Int J Oncol (2008) 1.12
Role of the phosphatidylinositol 3'-kinase-Akt signal pathway in the proliferation of human pancreatic ductal carcinoma cell lines. Pancreas (2004) 1.11
Multiple piloleiomyomas: do they follow dermatomes or blaschko lines? J Dermatol (2003) 1.11
Generation of structures formed by lens and retinal cells differentiating from embryonic stem cells. Dev Dyn (2003) 1.11
Long-term maintenance of brain tumor stem cell properties under at non-adherent and adherent culture conditions. Biochem Biophys Res Commun (2007) 1.11
Analysis of genetic and predisposing factors in Japanese patients with atypical hemolytic uremic syndrome. Mol Immunol (2013) 1.10
A multicenter, open-label, dose-ranging study to exploratively evaluate the efficacy, safety, and dose-response of tolvaptan in patients with decompensated liver cirrhosis. J Gastroenterol (2010) 1.10
Tumor cell radiosensitivity is a major determinant of tumor response to radiation. Cancer Res (2006) 1.10
Chemosensitivity profile of cancer cell lines and identification of genes determining chemosensitivity by an integrated bioinformatical approach using cDNA arrays. Mol Cancer Ther (2005) 1.10
Hepatocellular carcinoma with sarcomatous change arising after radiofrequency ablation for well-differentiated hepatocellular carcinoma. Hepatol Res (2003) 1.09
Mutations of the Corynebacterium glutamicum NCgl1221 gene, encoding a mechanosensitive channel homolog, induce L-glutamic acid production. Appl Environ Microbiol (2007) 1.09
Development of gastric tumors in Apc(Min/+) mice by the activation of the beta-catenin/Tcf signaling pathway. Cancer Res (2007) 1.09
Inter- and intratumoral variability in magnetic resonance imaging of pleomorphic adenoma: an attempt to interpret the variable magnetic resonance findings. J Comput Assist Tomogr (2004) 1.09
Distinct osteoclast precursors in the bone marrow and extramedullary organs characterized by responsiveness to Toll-like receptor ligands and TNF-alpha. J Immunol (2003) 1.09
Proteomic identification of differentially-expressed genes in human gastric carcinomas. Proteomics (2005) 1.07
Clinical usefulness of serum telomerase reverse transcriptase (hTERT) mRNA and epidermal growth factor receptor (EGFR) mRNA as a novel tumor marker for lung cancer. Cancer Sci (2006) 1.07
Expression of Fas and Fas ligand in esophageal tissue mucosa and carcinomas. Int J Oncol (2002) 1.07
Preoperative chemotherapy and radiation therapy for squamous cell carcinoma of the maxillary sinus. Jpn J Clin Oncol (2005) 1.07
Guideline on the use of new anticancer drugs for the treatment of Hepatocellular Carcinoma 2010 update. Hepatol Res (2012) 1.07
Inhibition of the PI3K-Akt signaling pathway enhances the sensitivity of Fas-mediated apoptosis in human gastric carcinoma cell line, MKN-45. J Cancer Res Clin Oncol (2003) 1.06
Nucleotide analogs for patients with HBV-related hepatocellular carcinoma increase the survival rate through improved liver function. Intern Med (2009) 1.06
Genes and molecular pathways related to radioresistance of oral squamous cell carcinoma cells. Int J Cancer (2007) 1.05
Prostatic stromal sarcoma: case report and review of the literature. Pathol Int (2003) 1.05
Aberrant expression of selenoproteins in the progression of colorectal cancer. Cancer Lett (2007) 1.05
Evidence of lytic infection of Epstein-Barr virus (EBV) in EBV-positive gastric carcinoma. J Med Virol (2002) 1.05
Hepatocyte growth factor suppresses profibrogenic signal transduction via nuclear export of Smad3 with galectin-7. Gastroenterology (2008) 1.04
Arpp, a new homolog of carp, is preferentially expressed in type 1 skeletal muscle fibers and is markedly induced by denervation. Lab Invest (2002) 1.04
Genetic ablation of Rest leads to in vitro-specific derepression of neuronal genes during neurogenesis. Development (2012) 1.04
Cancer-associated fibroblasts and CD163-positive macrophages in oral squamous cell carcinoma: their clinicopathological and prognostic significance. J Oral Pathol Med (2012) 1.04
c-Kit-targeting immunotherapy for hereditary melanoma in a mouse model. Cancer Res (2004) 1.04
Circulating cell-free mRNA in plasma as a tumor marker for patients with primary and recurrent gastric cancer. Anticancer Res (2007) 1.03
The impact of visceral fat in nonalcoholic fatty liver disease: cross-sectional and longitudinal studies. J Gastroenterol (2007) 1.02
Complications of radiofrequency ablation for hepatocellular carcinoma in a multicenter study: An analysis of 16 346 treated nodules in 13 283 patients. Hepatol Res (2012) 1.02
Tubular-trabecular type Basal cell adenoma of the parotid gland: a patient report. Yonago Acta Med (2010) 1.02
Evaluation of novel modified tangential irradiation technique for breast cancer patients using dose-volume histograms. Int J Radiat Oncol Biol Phys (2004) 1.02
Lethality in PARP-1/Ku80 double mutant mice reveals physiological synergy during early embryogenesis. DNA Repair (Amst) (2003) 1.02
Cyclo-oxygenase-1 and -2 expression in human oral mucosa, dysplasias and squamous cell carcinomas and their pathological significance. Oral Oncol (2005) 1.02
Multipotent cell fate of neural crest-like cells derived from embryonic stem cells. Stem Cells (2006) 1.01
Serum human telomerase reverse transcriptase messenger RNA as a novel tumor marker for hepatocellular carcinoma. Clin Cancer Res (2005) 1.01
Japanese structure survey of radiation oncology in 2005 based on institutional stratification of patterns of care study. Int J Radiat Oncol Biol Phys (2008) 1.01
Expression of polo-like kinase 1 (PLK1) protein predicts the survival of patients with gastric carcinoma. Oncology (2006) 1.01
Expression of minichromosome maintenance 7 (MCM7) in small lung adenocarcinomas (pT1): Prognostic implication. Lung Cancer (2009) 1.01
Two distinct types of mouse melanocyte: differential signaling requirement for the maintenance of non-cutaneous and dermal versus epidermal melanocytes. Development (2009) 1.01
miR-29b, miR-205 and miR-221 enhance chemosensitivity to gemcitabine in HuH28 human cholangiocarcinoma cells. PLoS One (2013) 1.00
A new model of retinal photoreceptor cell degeneration induced by a chemical hypoxia-mimicking agent, cobalt chloride. Brain Res (2006) 1.00
High-fat, high-fructose diet induces hepatic iron overload via a hepcidin-independent mechanism prior to the onset of liver steatosis and insulin resistance in mice. Metabolism (2012) 1.00