Published in J Bioenerg Biomembr on August 01, 2004
Preconditioning and tolerance against cerebral ischaemia: from experimental strategies to clinical use. Lancet Neurol (2009) 2.98
Ischemic postconditioning as a novel avenue to protect against brain injury after stroke. J Cereb Blood Flow Metab (2009) 1.77
Limb remote-preconditioning protects against focal ischemia in rats and contradicts the dogma of therapeutic time windows for preconditioning. Neuroscience (2007) 1.61
The Akt signaling pathway contributes to postconditioning's protection against stroke; the protection is associated with the MAPK and PKC pathways. J Neurochem (2008) 1.54
Limb remote ischemic postconditioning protects against focal ischemia in rats. Brain Res (2009) 1.26
Ischemic conditioning by short periods of reperfusion attenuates renal ischemia/reperfusion induced apoptosis and autophagy in the rat. J Biomed Sci (2009) 1.09
From rapid to delayed and remote postconditioning: the evolving concept of ischemic postconditioning in brain ischemia. Curr Drug Targets (2012) 1.08
Mitochondrial potassium ATP channels and retinal ischemic preconditioning. Invest Ophthalmol Vis Sci (2006) 1.08
Preconditioning-induced ischemic tolerance: a window into endogenous gearing for cerebroprotection. Exp Transl Stroke Med (2010) 1.03
Hydrogen sulfide preconditioning or neutrophil depletion attenuates ischemia-reperfusion-induced mitochondrial dysfunction in rat small intestine. Am J Physiol Gastrointest Liver Physiol (2011) 1.01
The chronic protective effects of limb remote preconditioning and the underlying mechanisms involved in inflammatory factors in rat stroke. PLoS One (2012) 1.01
The Akt pathway is involved in rapid ischemic tolerance in focal ischemia in Rats. Transl Stroke Res (2010) 0.94
Mitochondria: the missing link between preconditioning and neuroprotection. J Alzheimers Dis (2010) 0.88
Transient ischemic attack before nonlacunar ischemic stroke in the elderly. J Stroke Cerebrovasc Dis (2008) 0.87
Signal transducers and activators of transcription: STATs-mediated mitochondrial neuroprotection. Antioxid Redox Signal (2011) 0.86
Biomarkers for ischemic preconditioning: finding the responders. J Cereb Blood Flow Metab (2014) 0.85
The Protective Effects of Ischemic Postconditioning against Stroke: From Rapid to Delayed and Remote Postconditioning. Open Drug Discov J (2011) 0.83
Preconditioning for traumatic brain injury. Transl Stroke Res (2012) 0.82
Signaling pathways leading to ischemic mitochondrial neuroprotection. J Bioenerg Biomembr (2014) 0.79
Ischemic tolerance as an active and intrinsic neuroprotective mechanism. Handb Clin Neurol (2009) 0.78
Age-related reduction of cerebral ischemic preconditioning: myth or reality? Clin Interv Aging (2013) 0.78
Protein Kinase C Epsilon Promotes Cerebral Ischemic Tolerance Via Modulation of Mitochondrial Sirt5. Sci Rep (2016) 0.75
Overview of Experimental and Clinical Findings regarding the Neuroprotective Effects of Cerebral Ischemic Postconditioning. Biomed Res Int (2017) 0.75
Untargeted metabolomics reveals a mild impact of remote ischemic conditioning on the plasma metabolome and α-hydroxybutyrate as a possible cardioprotective factor and biomarker of tissue ischemia. Metabolomics (2017) 0.75
The respiratory chain and oxidative phosphorylation. Adv Enzymol Relat Subj Biochem (1956) 20.40
Preconditioning with ischemia: a delay of lethal cell injury in ischemic myocardium. Circulation (1986) 19.82
Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked. Science (1997) 16.09
The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis. Science (1997) 15.25
Glutamate-induced neuronal death: a succession of necrosis or apoptosis depending on mitochondrial function. Neuron (1995) 4.07
'Ischemic tolerance' phenomenon found in the brain. Brain Res (1990) 2.73
Oxidative stress and apoptosis. Pathophysiology (2000) 2.58
Neurodegeneration in excitotoxicity, global cerebral ischemia, and target deprivation: A perspective on the contributions of apoptosis and necrosis. Brain Res Bull (1998) 2.26
Mitochondrial dysfunction is a primary event in glutamate neurotoxicity. J Neurosci (1996) 1.99
Delayed neuronal death in the CA1 pyramidal cell layer of the gerbil hippocampus following transient ischemia is apoptosis. J Neurosci (1995) 1.95
Mitochondrial depolarization in glutamate-stimulated neurons: an early signal specific to excitotoxin exposure. J Neurosci (1996) 1.92
The influence of the time period between preconditioning ischemia and prolonged ischemia on myocardial protection. Cardioscience (1993) 1.87
To die or not to die for neurons in ischemia, traumatic brain injury and epilepsy: a review on the stress-activated signaling pathways and apoptotic pathways. Prog Neurobiol (2003) 1.66
Mitochondria in neurodegeneration: acute ischemia and chronic neurodegenerative diseases. J Cereb Blood Flow Metab (1999) 1.56
Epsilon PKC is required for the induction of tolerance by ischemic and NMDA-mediated preconditioning in the organotypic hippocampal slice. J Neurosci (2003) 1.50
Rapid preconditioning protects rats against ischemic neuronal damage after 3 but not 7 days of reperfusion following global cerebral ischemia. J Cereb Blood Flow Metab (1997) 1.50
Free radicals in cerebral ischemia. Stroke (1978) 1.48
Ischemic delayed neuronal death. A mitochondrial hypothesis. Stroke (1995) 1.32
Ischemic preconditioning in rats: role of mitochondrial K(ATP) channel in preservation of mitochondrial function. Am J Physiol Heart Circ Physiol (2000) 1.29
Mitochondria accumulate Ca2+ following intense glutamate stimulation of cultured rat forebrain neurones. J Physiol (1997) 1.24
Focal ischemic preconditioning induces rapid tolerance to middle cerebral artery occlusion in mice. J Cereb Blood Flow Metab (1999) 1.23
Mitochondrial permeability transition in acute neurodegeneration. Biochimie (2002) 1.21
Rapid cerebral ischemic preconditioning in mice deficient in endothelial and neuronal nitric oxide synthases. Stroke (2003) 1.19
Apoptosis and necrosis after reversible focal ischemia: an in situ DNA fragmentation analysis. J Cereb Blood Flow Metab (1996) 1.17
Oxygen radicals in focal cerebral ischemia. Brain Pathol (1994) 1.16
Ischemic preconditioning preserves mitochondrial function after global cerebral ischemia in rat hippocampus. J Cereb Blood Flow Metab (2001) 1.15
Free radicals in CNS injury. Res Publ Assoc Res Nerv Ment Dis (1993) 1.13
Adaptation of adult brain tissue to anoxia and hypoxia in vitro. Brain Res (1986) 1.07
Anoxic preconditioning in hippocampal slices: role of adenosine. Neuroscience (1996) 1.07
Rapid preconditioning neuroprotection following anoxia in hippocampal slices: role of the K+ ATP channel and protein kinase C. Neuroscience (1999) 1.02
Cytochrome C is released from mitochondria into the cytosol after cerebral anoxia or ischemia. J Cereb Blood Flow Metab (1999) 1.02
Rapid tolerance to focal cerebral ischemia in rats is attenuated by adenosine A1 receptor antagonist. J Cereb Blood Flow Metab (2002) 1.01
Diazepam promotes ATP recovery and prevents cytochrome c release in hippocampal slices after in vitro ischemia. J Neurochem (2000) 0.92
Oxygen radicals in CNS damage. Chem Biol Interact (1989) 0.92
Oxygen, antioxidants and brain dysfunction. Yonsei Med J (1993) 0.92
Mitochondrial hyperoxidation signals residual intracellular dysfunction after global ischemia in rat neocortex. J Cereb Blood Flow Metab (1995) 0.91
Influence of acidosis on lipid peroxidation in brain tissues in vitro. J Cereb Blood Flow Metab (1985) 0.90
Antioxidants, mitochondrial hyperoxidation and electrical recovery after anoxia in hippocampal slices. Brain Res (1997) 0.89
NADH fluorescence and regional energy metabolites during focal ischemia and reperfusion of rat brain. J Cereb Blood Flow Metab (1991) 0.87
Calcium influx from the extracellular space promotes NADH hyperoxidation and electrical dysfunction after anoxia in hippocampal slices. J Cereb Blood Flow Metab (1998) 0.87
Ischemic injury to rat forebrain mitochondria and cellular calcium homeostasis. Biochim Biophys Acta (1992) 0.86
Preconditioning preserves mitochondrial function and glycolytic flux during an early period of reperfusion in perfused rat hearts. Cardiovasc Res (1997) 0.84
Columnar alterations of NADH fluorescence during hypoxia-ischemia in immature rat brain. J Cereb Blood Flow Metab (1982) 0.84
Nitric oxide is involved in anoxic preconditioning neuroprotection in rat hippocampal slices. Brain Res (1999) 0.84
Preconditioning of primary rat neuronal cultures against ischemic injury: characterization of the "time window of protection'. Brain Res (1996) 0.84
Differing neurochemical and morphological sequelae of global ischemia: comparison of single- and multiple-insult paradigms. J Neurochem (1992) 0.83
The mechanism of neuronal resistance and adaptation to hypoxia. FEBS Lett (1987) 0.83
Effect of peroxide, sodium, and calcium on brain mitochondrial respiration in vitro: potential role in cerebral ischemia and reperfusion. J Neurochem (1990) 0.83
The biochemical basis of ischemic brain lesions. Arzneimittelforschung (1991) 0.83
Altered mitochondrial respiration in selectively vulnerable brain subregions following transient forebrain ischemia in the rat. J Neurochem (1987) 0.83
Calcium and increase excitability promote tolerance against anoxia in hippocampal slices. Brain Res (1999) 0.82
Anoxia-induced gene expression in turtle heart. Upregulation of mitochondrial genes for NADH-ubiquinone oxidoreductase subunit 5 and cytochrome c oxidase subunit 1. Eur J Biochem (1996) 0.81
Isoform-specific membrane translocation of protein kinase C after ischemic preconditioning. Neurochem Res (2001) 0.80
Ischemic injury in the brain. Role of oxygen radical-mediated processes. Ann N Y Acad Sci (1989) 0.80
Mitochondrial hyperoxidation after cerebral anoxia/ischemia. Epiphenomenon or precursor to residual damage? Adv Exp Med Biol (1997) 0.80
Effect of the first window of ischemic preconditioning on mitochondrial dysfunction following global cerebral ischemia. Mitochondrion (2002) 0.80
Induction of tolerance to ischemia: alterations in second-messenger systems in the gerbil hippocampus. Brain Res Bull (1992) 0.79
Changes in non-synaptosomal and synaptosomal mitochondrial membrane-linked enzymatic activities after transient cerebral ischemia. Neurochem Res (1994) 0.78
Hypoxia and oxygen toxicity. Adv Neurol (1979) 0.78
The effect of rapid preconditioning on the microglial, astrocytic and neuronal consequences of global cerebral ischemia. Acta Neuropathol (1999) 0.78
Global myocardial ischemia protects the myocardium from subsequent regional ischemia. Cardioscience (1993) 0.78
MK-801 (dizocilpine) protects the brain from repeated normothermic global ischemic insults in the rat. J Cereb Blood Flow Metab (1993) 0.76