PubRank

R N Armstrong

Author PubWeight™ 52.20‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Structure determination and refinement of human alpha class glutathione transferase A1-1, and a comparison with the Mu and Pi class enzymes. J Mol Biol 1993 2.66
2 The three-dimensional structure of a glutathione S-transferase from the mu gene class. Structural analysis of the binary complex of isoenzyme 3-3 and glutathione at 2.2-A resolution. Biochemistry 1992 2.43
3 FosB, a cysteine-dependent fosfomycin resistance protein under the control of sigma(W), an extracytoplasmic-function sigma factor in Bacillus subtilis. J Bacteriol 2001 1.83
4 Three-dimensional structure, catalytic properties, and evolution of a sigma class glutathione transferase from squid, a progenitor of the lens S-crystallins of cephalopods. Biochemistry 1995 1.66
5 Fosfomycin resistance protein (FosA) is a manganese metalloglutathione transferase related to glyoxalase I and the extradiol dioxygenases. Biochemistry 1997 1.54
6 Contribution of tyrosine 6 to the catalytic mechanism of isoenzyme 3-3 of glutathione S-transferase. J Biol Chem 1992 1.54
7 Structure and function of the xenobiotic substrate binding site of a glutathione S-transferase as revealed by X-ray crystallographic analysis of product complexes with the diastereomers of 9-(S-glutathionyl)-10-hydroxy-9,10-dihydrophenanthrene. Biochemistry 1994 1.28
8 Spectroscopic and kinetic evidence for the thiolate anion of glutathione at the active site of glutathione S-transferase. Biochemistry 1989 1.26
9 Elucidation of a monovalent cation dependence and characterization of the divalent cation binding site of the fosfomycin resistance protein (FosA). Biochemistry 1999 1.19
10 Dissection of the catalytic mechanism of isozyme 4-4 of glutathione S-transferase with alternative substrates. Biochemistry 1988 1.18
11 Snapshots along the reaction coordinate of an SNAr reaction catalyzed by glutathione transferase. Biochemistry 1993 1.18
12 Tyrosine 115 participates both in chemical and physical steps of the catalytic mechanism of a glutathione S-transferase. J Biol Chem 1993 1.18
13 Sulfhydryl group reactivity of adenosine 3',5'-monophosphate dependent protein kinase from bovine heart: a probe of holoenzyme structure. Biochemistry 1978 1.15
14 Formation of the 1-(S-glutathionyl)-2,4,6-trinitrocyclohexadienate anion at the active site of glutathione S-transferase: evidence for enzymic stabilization of sigma-complex intermediates in nucleophilic aromatic substitution reactions. Biochemistry 1989 1.07
15 Equilibrium folding of dimeric class mu glutathione transferases involves a stable monomeric intermediate. Biochemistry 2000 1.02
16 Magnetic resonance and kinetic studies of the manganese(II) ion and substrate complexes of the catalytic subunit of adenosine 3',5'-monophosphate dependent protein kinase from bovine heart. Biochemistry 1979 1.02
17 Mechanism of microsomal epoxide hydrolase. Semifunctional site-specific mutants affecting the alkylation half-reaction. Biochemistry 1998 1.01
18 Crystallization and a preliminary X-ray diffraction study of isozyme 3-3 of glutathione S-transferase from rat liver. J Mol Biol 1987 0.95
19 Electrostatic interactions affecting the active site of class sigma glutathione S-transferase. Biochem J 2000 0.93
20 First-sphere and second-sphere electrostatic effects in the active site of a class mu gluthathione transferase. Biochemistry 1996 0.93
21 Location of a potential transport binding site in a sigma class glutathione transferase by x-ray crystallography. Proc Natl Acad Sci U S A 1996 0.92
22 Class sigma glutathione transferase unfolds via a dimeric and a monomeric intermediate: impact of subunit interface on conformational stability in the superfamily. Biochemistry 1998 0.92
23 Microsomal and soluble epoxide hydrolases are members of the same family of C-X bond hydrolase enzymes. Chem Res Toxicol 1994 0.91
24 Synthesis and characterization of the oxygen and desthio analogues of glutathione as dead-end inhibitors of glutathione S-transferase. Biochem Biophys Res Commun 1985 0.91
25 Construction, expression, and preliminary characterization of chimeric class mu glutathione S-transferases with altered catalytic properties. Biopolymers 1990 0.90
26 Stereoselective catalysis of a retro-Michael reaction by class mu glutathione transferases. Consequences for the internal distribution of products in the active site. Chem Res Toxicol 1995 0.89
27 Cyclic AMP-dependent ATPase activity of bovine heart protein kinase. Proc Natl Acad Sci U S A 1979 0.88
28 Conformational changes in the crystal structure of rat glutathione transferase M1-1 with global substitution of 3-fluorotyrosine for tyrosine. J Mol Biol 1998 0.87
29 Modular mutagenesis of exons 1, 2, and 8 of a glutathione S-transferase from the mu class. Mechanistic and structural consequences for chimeras of isoenzyme 3-3. Biochemistry 1992 0.87
30 Stereoselectivity of isozyme C of glutathione S-transferase toward arene and azaarene oxides. Biochemistry 1983 0.86
31 Are the histidine residues of glutathione S-transferase important in catalysis? An assessment by 13C NMR spectroscopy and site-specific mutagenesis. J Biol Chem 1991 0.86
32 Semifunctional site-specific mutants affecting the hydrolytic half-reaction of microsomal epoxide hydrolase. Biochemistry 1998 0.86
33 Enantioselectivity of microsomal epoxide hydrolase toward arene oxide substrates. J Biol Chem 1981 0.85
34 Kinetic analysis of the slow ionization of glutathione by microsomal glutathione transferase MGST1. Biochemistry 2001 0.85
35 Enzymes harboring unnatural amino acids: mechanistic and structural analysis of the enhanced catalytic activity of a glutathione transferase containing 5-fluorotryptophan. Biochemistry 1998 0.85
36 Elementary steps in the acquisition of Mn2+ by the fosfomycin resistance protein (FosA). Biochemistry 2001 0.84
37 Genome-wide profiling of methylation identifies novel targets with aberrant hypermethylation and reduced expression in low-risk myelodysplastic syndromes. Leukemia 2012 0.84
38 Rational reconstruction of the active site of a class mu glutathione S-transferase. J Biol Chem 1994 0.82
39 Interaction of hepatic microsomal epoxide hydrolase derived from a recombinant baculovirus expression system with an azarene oxide and an aziridine substrate analogue. Biochemistry 1993 0.81
40 Active-site tyrosyl residues are targets in the irreversible inhibition of a class Mu glutathione transferase by 2-(S-glutathionyl)-3,5,6-trichloro-1,4-benzoquinone. J Biol Chem 1994 0.81
41 Conjugation of haloalkanes by bacterial and mammalian glutathione transferases: mono- and vicinal dihaloethanes. Chem Res Toxicol 2001 0.81
42 Hepatic microsomal epoxide hydrolase. Mechanistic studies of the hydration of K-region arene oxides. J Biol Chem 1980 0.80
43 On the glycosylation state of five rat hepatic microsomal cytochrome P-450 isozymes. J Biol Chem 1983 0.80
44 Mechanistic imperative for the evolution of a metalloglutathione transferase of the vicinal oxygen chelate superfamily. Chem Biol Interact 1998 0.80
45 Conjugation of haloalkanes by bacterial and mammalian glutathione transferases: mono- and dihalomethanes. Chem Res Toxicol 2001 0.79
46 Observation of a substituent effect on the stereoselectivity of glutathione S-transferase toward para-substituted 4-phenyl-3-buten-2-ones. Chem Res Toxicol 1992 0.78
47 Investigation of the kinetic and stereochemical recognition of arene and azaarene oxides by isozymes A2 and C2 of glutathione S-transferase. Biochem Biophys Res Commun 1984 0.78
48 Stereoselective formation of benz[a]anthracene (+)-(5S,6R)-oxide and (+)-(8R,9S)-oxide by a highly purified and reconstituted system containing cytochrome P-450c. Biochem Biophys Res Commun 1982 0.78
49 An enantiomeric interaction in the metabolism and tumorigenicity of (+)- and (-)-benzo[a]pyrene 7,8-oxide. J Biol Chem 1980 0.78
50 Nuclear magnetic resonance studies of the conformation of tetraamminecobalt (III)--ATP bound at the active site of bovine heart protein kinase. Biochemistry 1979 0.78
51 Stereoselectivity of rat liver cytochrome P-450c on formation of benzo[a]pyrene 4,5-oxide. Biochem Biophys Res Commun 1981 0.75
52 Stereoselective product inhibition of glutathione S-transferase. Biochem Biophys Res Commun 1986 0.75
53 Pricing medical services in the managed care environment. Top Health Care Financ 1992 0.75
54 Polycyclic aromatic hydrocarbon quinones and glutathione thioethers as substrates and inhibitors of the human placental NADP-linked 15-hydroxyprostaglandin dehydrogenase. J Biol Chem 1987 0.75
55 Stereoselectivity and regioselectivity of uridine-5'-diphosphoglucuronosyltransferase toward vicinal dihydrodiols of polycyclic aromatic hydrocarbons. Biochemistry 1983 0.75
56 Stereoselectivity and enantioselectivity of glutathione S-transferase toward stilbene oxide substrates. Biochem Int 1987 0.75