Published in J Neurochem on October 01, 2004
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Activation of the phosphoinositide 3-kinase-Akt-mammalian target of rapamycin signaling pathway is required for metabotropic glutamate receptor-dependent long-term depression. J Neurosci (2004) 3.04
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The adaptor protein of the anaphase promoting complex Cdh1 is essential in maintaining replicative lifespan and in learning and memory. Nat Cell Biol (2008) 2.53
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The translation repressor 4E-BP2 is critical for eIF4F complex formation, synaptic plasticity, and memory in the hippocampus. J Neurosci (2005) 2.33
Regulation of eukaryotic initiation factor 4E by converging signaling pathways during metabotropic glutamate receptor-dependent long-term depression. J Neurosci (2006) 2.04
Exaggerated translation causes synaptic and behavioural aberrations associated with autism. Nature (2012) 1.98
NADPH oxidase mediates hypersomnolence and brain oxidative injury in a murine model of sleep apnea. Am J Respir Crit Care Med (2005) 1.91
Local RNA translation at the synapse and in disease. J Neurosci (2011) 1.83
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Removal of FKBP12 enhances mTOR-Raptor interactions, LTP, memory, and perseverative/repetitive behavior. Neuron (2008) 1.80
NADPH oxidase immunoreactivity in the mouse brain. Brain Res (2003) 1.74
Reactive oxygen species and synaptic plasticity in the aging hippocampus. Ageing Res Rev (2004) 1.72
Sources and targets of reactive oxygen species in synaptic plasticity and memory. Antioxid Redox Signal (2007) 1.69
Synaptic localization of a functional NADPH oxidase in the mouse hippocampus. Mol Cell Neurosci (2005) 1.61
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Dysregulation of the mTOR pathway mediates impairment of synaptic plasticity in a mouse model of Alzheimer's disease. PLoS One (2010) 1.49
Aging-dependent alterations in synaptic plasticity and memory in mice that overexpress extracellular superoxide dismutase. J Neurosci (2006) 1.38
Reactive oxygen species in the regulation of synaptic plasticity and memory. Antioxid Redox Signal (2010) 1.37
Persistent pain is dependent on spinal mitochondrial antioxidant levels. J Neurosci (2009) 1.36
Removal of S6K1 and S6K2 leads to divergent alterations in learning, memory, and synaptic plasticity. Learn Mem (2008) 1.35
Synaptic plasticity deficits and mild memory impairments in mouse models of chronic granulomatous disease. Mol Cell Biol (2006) 1.35
Hippocampal long-term potentiation, memory, and longevity in mice that overexpress mitochondrial superoxide dismutase. Neurobiol Learn Mem (2006) 1.32
Alterations in intrinsic membrane properties and the axon initial segment in a mouse model of Angelman syndrome. J Neurosci (2011) 1.31
mGluR-dependent long-term depression is associated with increased phosphorylation of S6 and synthesis of elongation factor 1A but remains expressed in S6K-deficient mice. Mol Cell Biol (2008) 1.30
Characterization and reversal of synaptic defects in the amygdala in a mouse model of fragile X syndrome. Proc Natl Acad Sci U S A (2010) 1.29
Synaptic plasticity and translation initiation. Learn Mem (2004) 1.27
ERK and mTOR signaling couple beta-adrenergic receptors to translation initiation machinery to gate induction of protein synthesis-dependent long-term potentiation. J Biol Chem (2007) 1.27
Role of reactive oxygen species in hippocampal long-term potentiation: contributory or inhibitory? J Neurosci Res (2002) 1.26
The Down syndrome critical region protein RCAN1 regulates long-term potentiation and memory via inhibition of phosphatase signaling. J Neurosci (2007) 1.26
Rapid isolation of synaptoneurosomes and postsynaptic densities from adult mouse hippocampus. J Neurosci Methods (2006) 1.25
Brain-specific disruption of the eIF2α kinase PERK decreases ATF4 expression and impairs behavioral flexibility. Cell Rep (2012) 1.24
Altered hippocampal synaptic plasticity in the FMR1 gene family knockout mouse models. J Neurophysiol (2009) 1.24
Long-term depression in the adult hippocampus in vivo involves activation of extracellular signal-regulated kinase and phosphorylation of Elk-1. J Neurosci (2002) 1.22
Inhibition of the interactions between eukaryotic initiation factors 4E and 4G impairs long-term associative memory consolidation but not reconsolidation. Proc Natl Acad Sci U S A (2011) 1.22
NADPH oxidase is required for NMDA receptor-dependent activation of ERK in hippocampal area CA1. J Neurochem (2005) 1.21
CYFIP1 coordinates mRNA translation and cytoskeleton remodeling to ensure proper dendritic spine formation. Neuron (2013) 1.21
Overexpression of SOD-2 reduces hippocampal superoxide and prevents memory deficits in a mouse model of Alzheimer's disease. Proc Natl Acad Sci U S A (2009) 1.20
Potentiation of hippocampal synaptic transmission by superoxide requires the oxidative activation of protein kinase C. J Neurosci (2002) 1.15
Behavioral alterations in mice lacking the translation repressor 4E-BP2. Neurobiol Learn Mem (2006) 1.15
Amyloid β-induced impairments in hippocampal synaptic plasticity are rescued by decreasing mitochondrial superoxide. J Neurosci (2011) 1.14
Activation of exchange protein activated by cyclic-AMP enhances long-lasting synaptic potentiation in the hippocampus. Learn Mem (2008) 1.11
Macroautophagy deficiency mediates age-dependent neurodegeneration through a phospho-tau pathway. Mol Neurodegener (2012) 1.10
Impaired social interactions and motor learning skills in tuberous sclerosis complex model mice expressing a dominant/negative form of tuberin. Neurobiol Dis (2011) 1.09
Altered signaling pathways underlying abnormal hippocampal synaptic plasticity in the Ts65Dn mouse model of Down syndrome. J Neurochem (2006) 1.09
Early maintenance of hippocampal mossy fiber--long-term potentiation depends on protein and RNA synthesis and presynaptic granule cell integrity. J Neurosci (2003) 1.06
Glucagon-like peptide-1 cleavage product GLP-1(9-36) amide rescues synaptic plasticity and memory deficits in Alzheimer's disease model mice. J Neurosci (2012) 1.04
Genetic and acute CPEB1 depletion ameliorate fragile X pathophysiology. Nat Med (2013) 1.04
Metabotropic glutamate receptor-dependent long-term depression is impaired due to elevated ERK signaling in the ΔRG mouse model of tuberous sclerosis complex. Neurobiol Dis (2011) 1.03
Effects of GDNF on 6-OHDA-induced death in a dopaminergic cell line: modulation by inhibitors of PI3 kinase and MEK. J Neurosci Res (2003) 1.03
Reversal of impaired hippocampal long-term potentiation and contextual fear memory deficits in Angelman syndrome model mice by ErbB inhibitors. Biol Psychiatry (2012) 1.02
Haloperidol regulates the state of phosphorylation of ribosomal protein S6 via activation of PKA and phosphorylation of DARPP-32. Neuropsychopharmacology (2011) 1.00
Amyloid β: linking synaptic plasticity failure to memory disruption in Alzheimer's disease. J Neurochem (2011) 0.98
Superoxide-induced potentiation in the hippocampus requires activation of ryanodine receptor type 3 and ERK. J Neurophysiol (2008) 0.96
Identification of fragile X syndrome specific molecular markers in human fibroblasts: a useful model to test the efficacy of therapeutic drugs. Hum Mutat (2014) 0.95
Mitochondrial superoxide contributes to blood flow and axonal transport deficits in the Tg2576 mouse model of Alzheimer's disease. PLoS One (2010) 0.94
Genetic reduction of the α1 subunit of Na/K-ATPase corrects multiple hippocampal phenotypes in Angelman syndrome. Cell Rep (2013) 0.94
Calcium release by ryanodine receptors mediates hydrogen peroxide-induced activation of ERK and CREB phosphorylation in N2a cells and hippocampal neurons. Cell Calcium (2006) 0.92
Activation of the extracellular signal-regulated kinase pathway contributes to the behavioral deficit of fragile x-syndrome. J Neurochem (2012) 0.89
Superoxide dismutase and hippocampal function: age and isozyme matter. Antioxid Redox Signal (2007) 0.89
NMDA receptor activation induces translocation and activation of Rac in mouse hippocampal area CA1. Biochem Biophys Res Commun (2006) 0.88
The E3 ligase APC/C-Cdh1 is required for associative fear memory and long-term potentiation in the amygdala of adult mice. Learn Mem (2012) 0.88
Dysregulated mTORC1-Dependent Translational Control: From Brain Disorders to Psychoactive Drugs. Front Behav Neurosci (2011) 0.88
Interleukin-1beta induces beta-calcitonin gene-related peptide secretion in human type II alveolar epithelial cells. FASEB J (2004) 0.87
Cap-dependent translation initiation and memory. Prog Brain Res (2008) 0.87
Antipsychotics activate mTORC1-dependent translation to enhance neuronal morphological complexity. Sci Signal (2014) 0.87
Multiple components of eIF4F are required for protein synthesis-dependent hippocampal long-term potentiation. J Neurophysiol (2012) 0.87
In-depth quantitative proteomic analysis of de novo protein synthesis induced by brain-derived neurotrophic factor. J Proteome Res (2014) 0.86
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The eIF2α kinase PERK limits the expression of hippocampal metabotropic glutamate receptor-dependent long-term depression. Learn Mem (2014) 0.86
Mitochondrial superoxide: a key player in Alzheimer's disease. Aging (Albany NY) (2009) 0.86
Translocation and activation of Rac in the hippocampus during associative contextual fear learning. Neurobiol Learn Mem (2007) 0.85
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Basal variability in CREB phosphorylation predicts trait-like differences in amygdala-dependent memory. Proc Natl Acad Sci U S A (2013) 0.85
Neuronal expression of the ubiquitin E3 ligase APC/C-Cdh1 during development is required for long-term potentiation, behavioral flexibility, and extinction. Neurobiol Learn Mem (2012) 0.84
Regulator of calcineurin 1 modulates expression of innate anxiety and anxiogenic responses to selective serotonin reuptake inhibitor treatment. J Neurosci (2013) 0.83
NADPH oxidase mediates beta-amyloid peptide-induced activation of ERK in hippocampal organotypic cultures. Mol Brain (2009) 0.83
Fragile X mental retardation protein regulates heterosynaptic plasticity in the hippocampus. Learn Mem (2011) 0.82
Fragile X syndrome therapeutics S(C)TEP through the developmental window. Neuron (2012) 0.81
Production and secretion of calcitonin gene-related peptide from human lymphocytes. J Neuroimmunol (2002) 0.81
Coordinate regulation of mature dopaminergic axon morphology by macroautophagy and the PTEN signaling pathway. PLoS Genet (2013) 0.80
Early changes in the apparent diffusion coefficient (ADC) in a mouse model of Sandhoff's disease occur prior to disease symptoms and behavioral deficits. Magn Reson Med (2009) 0.79
Prohibitin viral gene transfer protects hippocampal CA1 neurons from ischemia and ameliorates postischemic hippocampal dysfunction. Stroke (2014) 0.78
Lipopolysaccharide evoked peptide release by calcium-induced calcium release. Neuroreport (2004) 0.77
The molecular basis of cognitive deficits in pervasive developmental disorders. Learn Mem (2012) 0.77
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Switching gears: translational mastery of transcription during memory formation. Neuron (2007) 0.76
Comparison of calcitonin gene-related peptide release from rat lymphocytes and dorsal root ganglia neurons. Brain Behav Immun (2002) 0.75