David G Huntsman

Author PubWeight™ 178.24‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 ARID1A mutations in endometriosis-associated ovarian carcinomas. N Engl J Med 2010 13.07
2 Association between endometriosis and risk of histological subtypes of ovarian cancer: a pooled analysis of case-control studies. Lancet Oncol 2012 5.70
3 Mutation of FOXL2 in granulosa-cell tumors of the ovary. N Engl J Med 2009 5.63
4 MHC class II transactivator CIITA is a recurrent gene fusion partner in lymphoid cancers. Nature 2011 3.22
5 Use of immunohistochemical markers can refine prognosis in triple negative breast cancer. BMC Cancer 2007 3.09
6 Amplification of PVT1 contributes to the pathophysiology of ovarian and breast cancer. Clin Cancer Res 2007 2.94
7 Subtype-specific mutation of PPP2R1A in endometrial and ovarian carcinomas. J Pathol 2011 2.64
8 Evolution of an adenocarcinoma in response to selection by targeted kinase inhibitors. Genome Biol 2010 2.60
9 Frequency of the TMPRSS2:ERG gene fusion is increased in moderate to poorly differentiated prostate cancers. J Clin Pathol 2007 2.48
10 Hormone-receptor expression and ovarian cancer survival: an Ovarian Tumor Tissue Analysis consortium study. Lancet Oncol 2013 2.48
11 A variant TMPRSS2 isoform and ERG fusion product in prostate cancer with implications for molecular diagnosis. Mod Pathol 2007 2.47
12 Ovarian carcinomas with genetic and epigenetic BRCA1 loss have distinct molecular abnormalities. BMC Cancer 2008 2.47
13 Distinct evolutionary trajectories of primary high-grade serous ovarian cancers revealed through spatial mutational profiling. J Pathol 2013 2.35
14 Recurrent somatic DICER1 mutations in nonepithelial ovarian cancers. N Engl J Med 2011 2.25
15 FOXA1 expression in breast cancer--correlation with luminal subtype A and survival. Clin Cancer Res 2007 2.22
16 CDH1 truncating mutations in the E-cadherin gene: an indication for total gastrectomy to treat hereditary diffuse gastric cancer. Ann Surg 2007 2.10
17 PIK3CA and PIK3CB inhibition produce synthetic lethality when combined with estrogen deprivation in estrogen receptor-positive breast cancer. Cancer Res 2009 2.01
18 Amplification of 11q13 in ovarian carcinoma. Genes Chromosomes Cancer 2008 2.01
19 Loss of BAF250a (ARID1A) is frequent in high-grade endometrial carcinomas. J Pathol 2011 1.91
20 Intraepithelial T cells and prognosis in ovarian carcinoma: novel associations with stage, tumor type, and BRCA1 loss. Mod Pathol 2008 1.90
21 Overexpression of the anti-adhesin podocalyxin is an independent predictor of breast cancer progression. Cancer Res 2004 1.90
22 Differences in tumor type in low-stage versus high-stage ovarian carcinomas. Int J Gynecol Pathol 2010 1.87
23 Germline BRCA1 and BRCA2 mutations in ovarian cancer: utility of a histology-based referral strategy. Obstet Gynecol 2012 1.86
24 Cyclin D1 as a diagnostic immunomarker for endometrial stromal sarcoma with YWHAE-FAM22 rearrangement. Am J Surg Pathol 2012 1.83
25 IL6-STAT3-HIF signaling and therapeutic response to the angiogenesis inhibitor sunitinib in ovarian clear cell cancer. Clin Cancer Res 2011 1.79
26 Type I gamma phosphatidylinositol phosphate kinase modulates adherens junction and E-cadherin trafficking via a direct interaction with mu 1B adaptin. J Cell Biol 2007 1.78
27 Automated quantitative analysis of estrogen receptor expression in breast carcinoma does not differ from expert pathologist scoring: a tissue microarray study of 3,484 cases. Breast Cancer Res Treat 2007 1.75
28 Type-specific cell line models for type-specific ovarian cancer research. PLoS One 2013 1.73
29 The autophagy protein LC3A correlates with hypoxia and is a prognostic marker of patient survival in clear cell ovarian cancer. J Pathol 2012 1.72
30 Assessment of interlaboratory variation in the immunohistochemical determination of estrogen receptor status using a breast cancer tissue microarray. Am J Clin Pathol 2002 1.67
31 Hierarchical clustering analysis of tissue microarray immunostaining data identifies prognostically significant groups of breast carcinoma. Clin Cancer Res 2004 1.67
32 Model of the early development of diffuse gastric cancer in E-cadherin mutation carriers and its implications for patient screening. J Pathol 2004 1.59
33 Deregulation of MYCN, LIN28B and LET7 in a molecular subtype of aggressive high-grade serous ovarian cancers. PLoS One 2011 1.57
34 Clear cell carcinoma of the ovary: a report from the first Ovarian Clear Cell Symposium, June 24th, 2010. Gynecol Oncol 2011 1.55
35 Association of TMPRSS2-ERG gene fusion with clinical characteristics and outcomes: results from a population-based study of prostate cancer. BMC Cancer 2008 1.54
36 Identification of sister chromatids by DNA template strand sequences. Nature 2009 1.53
37 14-3-3 fusion oncogenes in high-grade endometrial stromal sarcoma. Proc Natl Acad Sci U S A 2012 1.51
38 Coexpression of the type 1 growth factor receptor family members HER-1, HER-2, and HER-3 has a synergistic negative prognostic effect on breast carcinoma survival. Cancer 2005 1.47
39 Molecular characterization of mucinous ovarian tumours supports a stratified treatment approach with HER2 targeting in 19% of carcinomas. J Pathol 2013 1.47
40 Characterization of a recurrent germ line mutation of the E-cadherin gene: implications for genetic testing and clinical management. Clin Cancer Res 2005 1.46
41 Hereditary diffuse gastric cancer: association with lobular breast cancer. Fam Cancer 2008 1.45
42 HER2 overexpression and amplification is present in a subset of ovarian mucinous carcinomas and can be targeted with trastuzumab therapy. BMC Cancer 2009 1.43
43 ESR1 gene amplification in breast cancer: a common phenomenon? Nat Genet 2008 1.33
44 Establishment of subrenal capsule xenografts of primary human ovarian tumors in SCID mice: potential models. Gynecol Oncol 2005 1.33
45 Stromal mast cells in invasive breast cancer are a marker of favourable prognosis: a study of 4,444 cases. Breast Cancer Res Treat 2007 1.30
46 Evolutionary concepts in biobanking - the BC BioLibrary. J Transl Med 2009 1.29
47 Diagnosis of ovarian carcinoma cell type is highly reproducible: a transcanadian study. Am J Surg Pathol 2010 1.29
48 The biological and clinical value of p53 expression in pelvic high-grade serous carcinomas. J Pathol 2010 1.28
49 A fluorescence in situ hybridization study of ETV6-NTRK3 fusion gene in secretory breast carcinoma. Genes Chromosomes Cancer 2004 1.24
50 The role of the fallopian tube in ovarian cancer. Clin Adv Hematol Oncol 2012 1.23
51 Biomarker-based ovarian carcinoma typing: a histologic investigation in the ovarian tumor tissue analysis consortium. Cancer Epidemiol Biomarkers Prev 2013 1.22
52 Insulin-like growth factor 2 mRNA binding protein 3 (IGF2BP3) overexpression in pancreatic ductal adenocarcinoma correlates with poor survival. BMC Cancer 2010 1.22
53 DriverNet: uncovering the impact of somatic driver mutations on transcriptional networks in cancer. Genome Biol 2012 1.21
54 Xenografts of primary human gynecological tumors grown under the renal capsule of NOD/SCID mice show genetic stability during serial transplantation and respond to cytotoxic chemotherapy. Gynecol Oncol 2008 1.20
55 Stromal CD10 expression in invasive breast carcinoma correlates with poor prognosis, estrogen receptor negativity, and high grade. Mod Pathol 2006 1.19
56 Expression of class I histone deacetylases indicates poor prognosis in endometrioid subtypes of ovarian and endometrial carcinomas. Neoplasia 2008 1.19
57 Identification of novel therapeutic targets in microdissected clear cell ovarian cancers. PLoS One 2011 1.18
58 NRG1 gene rearrangements in clinical breast cancer: identification of an adjacent novel amplicon associated with poor prognosis. Oncogene 2005 1.16
59 CAMK1D amplification implicated in epithelial-mesenchymal transition in basal-like breast cancer. Mol Oncol 2008 1.16
60 Kisspeptin and GPR54 immunoreactivity in a cohort of 518 patients defines favourable prognosis and clear cell subtype in ovarian carcinoma. BMC Med 2007 1.15
61 Tumor growth inhibition by olaparib in BRCA2 germline-mutated patient-derived ovarian cancer tissue xenografts. Clin Cancer Res 2010 1.14
62 Type I gamma phosphatidylinositol phosphate kinase modulates invasion and proliferation and its expression correlates with poor prognosis in breast cancer. Breast Cancer Res 2010 1.14
63 Expression of the insulin-like growth factor I receptor and urokinase plasminogen activator in breast cancer is associated with poor survival: potential for intervention with 17-allylamino geldanamycin. Cancer Res 2004 1.13
64 BRCA1 and BRCA2 mutations correlate with TP53 abnormalities and presence of immune cell infiltrates in ovarian high-grade serous carcinoma. Mod Pathol 2012 1.12
65 Can clinically relevant prognostic subsets of breast cancer patients with four or more involved axillary lymph nodes be identified through immunohistochemical biomarkers? A tissue microarray feasibility study. Breast Cancer Res 2008 1.11
66 Tumor type and substage predict survival in stage I and II ovarian carcinoma: insights and implications. Gynecol Oncol 2009 1.10
67 De novo expression of CD44 variants in sporadic and hereditary gastric cancer. Lab Invest 2010 1.10
68 Assessment of Her-1, Her-2, And Her-3 expression and Her-2 amplification in advanced stage ovarian carcinoma. Int J Gynecol Pathol 2005 1.10
69 Fluorescence in situ hybridization for the detection of t(X;18)(p11.2;q11.2) in a synovial sarcoma tissue microarray using a breakapart-style probe. Diagn Mol Pathol 2005 1.09
70 The specificity of the FOXL2 c.402C>G somatic mutation: a survey of solid tumors. PLoS One 2009 1.07
71 Hereditary diffuse gastric cancer: diagnosis, genetic counseling, and prophylactic total gastrectomy. Cancer 2008 1.06
72 Calculator for ovarian carcinoma subtype prediction. Mod Pathol 2010 1.04
73 A functional proteogenomic analysis of endometrioid and clear cell carcinomas using reverse phase protein array and mutation analysis: protein expression is histotype-specific and loss of ARID1A/BAF250a is associated with AKT phosphorylation. BMC Cancer 2014 1.03
74 Expression of protein elongation factor eEF1A2 predicts favorable outcome in breast cancer. Breast Cancer Res Treat 2006 1.02
75 FOXL2 is a sensitive and specific marker for sex cord-stromal tumors of the ovary. Am J Surg Pathol 2011 1.01
76 Risk-reducing total gastrectomy for germline mutations in E-cadherin (CDH1): pathologic findings with clinical implications. Am J Surg Pathol 2008 1.00
77 Adult-type granulosa cell tumors and FOXL2 mutation. Cancer Res 2009 1.00
78 Hereditary diffuse gastric cancer: prophylactic surgical oncology implications. Surg Clin North Am 2008 1.00
79 Frequency of known gene rearrangements in endometrial stromal tumors. Am J Surg Pathol 2011 0.98
80 MDM2 protein expression is a negative prognostic marker in breast carcinoma. Mod Pathol 2006 0.97
81 Does massively parallel DNA resequencing signify the end of histopathology as we know it? J Pathol 2010 0.95
82 HER-3 overexpression is prognostic of reduced breast cancer survival: a study of 4046 patients. Ann Surg 2010 0.94
83 The prognostic significance of elongation factor eEF1A2 in ovarian cancer. Gynecol Oncol 2007 0.94
84 Using next-generation sequencing for the diagnosis of rare disorders: a family with retinitis pigmentosa and skeletal abnormalities. J Pathol 2011 0.94
85 Costs and benefits of opportunistic salpingectomy as an ovarian cancer prevention strategy. Obstet Gynecol 2015 0.93
86 Small cell ovarian carcinoma: genomic stability and responsiveness to therapeutics. Orphanet J Rare Dis 2013 0.93
87 Elevated expression of DecR1 impairs ErbB2/Neu-induced mammary tumor development. Mol Cell Biol 2007 0.93
88 Morphologic and Molecular Characteristics of Mixed Epithelial Ovarian Cancers. Am J Surg Pathol 2015 0.91
89 Co-amplification of CCND1 and EMSY is associated with an adverse outcome in ER-positive tamoxifen-treated breast cancers. Breast Cancer Res Treat 2009 0.91
90 Biomarker expression in pelvic high-grade serous carcinoma: comparison of ovarian and omental sites. Int J Gynecol Pathol 2011 0.91
91 The tubal hypothesis of ovarian cancer: caution needed. Lancet Oncol 2011 0.90
92 FOXL2 molecular testing in ovarian neoplasms: diagnostic approach and procedural guidelines. Mod Pathol 2013 0.90
93 P-cadherin expression as a prognostic biomarker in a 3992 case tissue microarray series of breast cancer. Mod Pathol 2010 0.89
94 Targeted mutation analysis of endometrial clear cell carcinoma. Histopathology 2015 0.89
95 beta-catenin (CTNNB1) gene amplification: a new mechanism of protein overexpression in cancer. Genes Chromosomes Cancer 2005 0.89
96 Immunohistochemical characterization of prototypical endometrial clear cell carcinoma--diagnostic utility of HNF-1β and oestrogen receptor. Histopathology 2013 0.88
97 Familial rhabdoid tumour 'avant la lettre'--from pathology review to exome sequencing and back again. J Pathol 2013 0.88
98 Periodic acid-schiff is superior to hematoxylin and eosin for screening prophylactic gastrectomies from CDH1 mutation carriers. Am J Surg Pathol 2010 0.86
99 Histotype-genotype correlation in 36 high-grade endometrial carcinomas. Am J Surg Pathol 2013 0.85
100 Ovarian cellular fibromas lack FOXL2 mutations: a useful diagnostic adjunct in the distinction from diffuse adult granulosa cell tumor. Am J Surg Pathol 2013 0.85
101 Differential subcellular expression of protein kinase C betaII in breast cancer: correlation with breast cancer subtypes. Breast Cancer Res Treat 2010 0.84
102 Predictive and prognostic protein biomarkers in epithelial ovarian cancer: recommendation for future studies. Cancers (Basel) 2010 0.83
103 The testosterone-dependent and independent transcriptional networks in the hypothalamus of Gpr54 and Kiss1 knockout male mice are not fully equivalent. BMC Genomics 2011 0.82
104 Endometrial stromal sarcomas with sex cord differentiation are associated with PHF1 rearrangement. Am J Surg Pathol 2013 0.81
105 Pregnancy after prophylactic total gastrectomy. Fam Cancer 2010 0.81
106 Specimen quality evaluation in Canadian biobanks participating in the COEUR repository. Biopreserv Biobank 2013 0.81
107 Endometrial sarcomas: an immunohistochemical and JAZF1 re-arrangement study in low-grade and undifferentiated tumors. Mod Pathol 2012 0.81
108 Cancer genomics: why rare is valuable. J Mol Med (Berl) 2015 0.80
109 Accelerating type-specific ovarian carcinoma research: Calculator for Ovarian Subtype Prediction (COSP) is a reliable high-throughput tool for case review. Histopathology 2013 0.80
110 Expression of integrin-linked kinase is not a useful prognostic marker in resected hepatocellular cancer. Anticancer Res 2008 0.79
111 Mutation discovery in regions of segmental cancer genome amplifications with CoNAn-SNV: a mixture model for next generation sequencing of tumors. PLoS One 2012 0.79
112 Dicer and Drosha in ovarian cancer. N Engl J Med 2009 0.79
113 YWHAE-FAM22 endometrial stromal sarcoma: diagnosis by reverse transcription-polymerase chain reaction in formalin-fixed, paraffin-embedded tumor. Hum Pathol 2012 0.78
114 Screening of symptomatic women for ovarian cancer. Lancet Oncol 2012 0.78
115 Copy number aberrations in benign serous ovarian tumors: a case for reclassification? Clin Cancer Res 2011 0.77
116 Surgical staging of early stage epithelial ovarian cancer. Gynecol Oncol 2011 0.77
117 Boveri at 100: Theodor Boveri and genetic predisposition to cancer. J Pathol 2014 0.77
118 Interobserver Agreement in Endometrial Carcinoma Histotype Diagnosis Varies Depending on The Cancer Genome Atlas (TCGA)-based Molecular Subgroup. Am J Surg Pathol 2017 0.77
119 Polymerase Epsilon Exonuclease Domain Mutations in Ovarian Endometrioid Carcinoma. Int J Gynecol Cancer 2015 0.76
120 Correction: Type-Specific Cell Line Models for Type-Specific Ovarian Cancer Research. PLoS One 2013 0.76
121 FOXL2 mutation is absent in uterine tumors resembling ovarian sex cord tumors. Am J Surg Pathol 2015 0.75
122 Diagnostic uncertainty in the interpretation of small atypical acinar lesions of prostate. Am J Surg Pathol 2010 0.75
123 Molecular determination of the breakpoints of a 161 556 bp deletion at chromosome 13q34 that presented as severe factor VII deficiency in a neonate. Br J Haematol 2007 0.75
124 Adult granulosa cell tumour-like areas occurring in ovarian epithelial neoplasms: report of a case series with investigation of FOXL2 mutation status. Histopathology 2013 0.75
125 BAF250a Expression in Atypical Endometriosis and Endometriosis-Associated Ovarian Cancer. Int J Gynecol Cancer 2016 0.75