Published in Diabetes on October 01, 2004
Herbal therapies for type 2 diabetes mellitus: chemistry, biology, and potential application of selected plants and compounds. Evid Based Complement Alternat Med (2013) 1.16
Betacellulin inhibits amylase and glucagon production and promotes beta cell differentiation in mouse embryonic pancreas. Diabetologia (2007) 0.88
Oreocnide integrifolia Flavonoids Augment Reprogramming for Islet Neogenesis and β-Cell Regeneration in Pancreatectomized BALB/c Mice. Evid Based Complement Alternat Med (2012) 0.83
Conophylline protects cells in cellular models of neurodegenerative diseases by inducing mammalian target of rapamycin (mTOR)-independent autophagy. J Biol Chem (2015) 0.79
Conophylline inhibits non-alcoholic steatohepatitis in mice. PLoS One (2017) 0.75
Plant-Derived Compounds Targeting Pancreatic Beta Cells for the Treatment of Diabetes. Evid Based Complement Alternat Med (2015) 0.75
Targeting BTK with ibrutinib in relapsed or refractory mantle-cell lymphoma. N Engl J Med (2013) 6.70
A modular analysis framework for blood genomics studies: application to systemic lupus erythematosus. Immunity (2008) 5.89
Parkin mediates nonclassical, proteasomal-independent ubiquitination of synphilin-1: implications for Lewy body formation. J Neurosci (2005) 3.92
Linear motif atlas for phosphorylation-dependent signaling. Sci Signal (2008) 3.77
Life span extension by calorie restriction depends on Rim15 and transcription factors downstream of Ras/PKA, Tor, and Sch9. PLoS Genet (2007) 3.07
BLAP75/RMI1 promotes the BLM-dependent dissolution of homologous recombination intermediates. Proc Natl Acad Sci U S A (2006) 3.00
A unified nomenclature for the superfamily of TRP cation channels. Mol Cell (2002) 2.99
BLAP75, an essential component of Bloom's syndrome protein complexes that maintain genome integrity. EMBO J (2005) 2.60
Between-hospital variation in treatment and outcomes in extremely preterm infants. N Engl J Med (2015) 2.59
Novel needle immersed vitrification: a practical and convenient method with potential advantages in mouse and human ovarian tissue cryopreservation. Hum Reprod (2008) 2.37
A histone-fold complex and FANCM form a conserved DNA-remodeling complex to maintain genome stability. Mol Cell (2010) 2.36
Genome-wide association identifies a susceptibility locus for coronary artery disease in the Chinese Han population. Nat Genet (2011) 2.32
A brassinosteroid transcriptional network revealed by genome-wide identification of BESI target genes in Arabidopsis thaliana. Plant J (2011) 2.19
Oxidative and electrophilic stress induces multidrug resistance-associated protein transporters via the nuclear factor-E2-related factor-2 transcriptional pathway. Hepatology (2007) 2.11
Nanochannel electroporation delivers precise amounts of biomolecules into living cells. Nat Nanotechnol (2011) 2.10
Valsalva manoeuver, intra-ocular pressure, cerebrospinal fluid pressure, optic disc topography: Beijing intracranial and intra-ocular pressure study. Acta Ophthalmol (2013) 2.09
Structural basis for flg22-induced activation of the Arabidopsis FLS2-BAK1 immune complex. Science (2013) 2.05
Addition of intrarectal local analgesia to periprostatic nerve block improves pain control for transrectal ultrasonography-guided prostate biopsy: a systematic review and meta-analysis. Int J Urol (2014) 2.01
Endoplasmic reticulum stress and mitochondrial cell death pathways mediate A53T mutant alpha-synuclein-induced toxicity. Hum Mol Genet (2005) 1.92
Src kinase mediates phosphatidylinositol 3-kinase/Akt-dependent rapid endothelial nitric-oxide synthase activation by estrogen. J Biol Chem (2002) 1.91
Alignment of optical maps. J Comput Biol (2006) 1.88
Arabidopsis plasma membrane protein crucial for Ca2+ influx and touch sensing in roots. Proc Natl Acad Sci U S A (2007) 1.86
Recruitment of fanconi anemia and breast cancer proteins to DNA damage sites is differentially governed by replication. Mol Cell (2009) 1.85
Disruption of PTEN coupling with 5-HT2C receptors suppresses behavioral responses induced by drugs of abuse. Nat Med (2006) 1.82
Defining the specificity space of the human SRC homology 2 domain. Mol Cell Proteomics (2007) 1.78
Nucleotide excision repair- and polymerase eta-mediated error-prone removal of mitomycin C interstrand cross-links. Mol Cell Biol (2003) 1.76
Glucose-TOR signalling reprograms the transcriptome and activates meristems. Nature (2013) 1.76
Three related receptor-like kinases are required for optimal cell elongation in Arabidopsis thaliana. Proc Natl Acad Sci U S A (2009) 1.74
Feasibility study of early blood pressure management in extremely preterm infants. J Pediatr (2012) 1.73
Genomic and proteomic analyses of the fungus Arthrobotrys oligospora provide insights into nematode-trap formation. PLoS Pathog (2011) 1.72
Sweet taste receptor expressed in pancreatic beta-cells activates the calcium and cyclic AMP signaling systems and stimulates insulin secretion. PLoS One (2009) 1.71
Insulin intervention in slowly progressive insulin-dependent (type 1) diabetes mellitus. J Clin Endocrinol Metab (2008) 1.67
Rad17 phosphorylation is required for claspin recruitment and Chk1 activation in response to replication stress. Mol Cell (2006) 1.65
miRDeep-P: a computational tool for analyzing the microRNA transcriptome in plants. Bioinformatics (2011) 1.65
Genomic instability and endoreduplication triggered by RAD17 deletion. Genes Dev (2003) 1.64
Nucleocytoplasmic shuttling of a GATA transcription factor functions as a development timer. Science (2014) 1.64
The Pso4 mRNA splicing and DNA repair complex interacts with WRN for processing of DNA interstrand cross-links. J Biol Chem (2005) 1.64
Ischemic insults direct glutamate receptor subunit 2-lacking AMPA receptors to synaptic sites. J Neurosci (2006) 1.63
REV3 and REV1 play major roles in recombination-independent repair of DNA interstrand cross-links mediated by monoubiquitinated proliferating cell nuclear antigen (PCNA). J Biol Chem (2006) 1.61
Inhibition of G1P3 expression found in the differential display study on respiratory syncytial virus infection. Virol J (2008) 1.60
Suppression of diabetes-induced retinal inflammation by blocking the angiotensin II type 1 receptor or its downstream nuclear factor-kappaB pathway. Invest Ophthalmol Vis Sci (2007) 1.59
Dicer is required for maintaining adult pancreas. PLoS One (2009) 1.59
Modulation of brassinosteroid-regulated gene expression by Jumonji domain-containing proteins ELF6 and REF6 in Arabidopsis. Proc Natl Acad Sci U S A (2008) 1.58
The biosurgical wound debridement: experimental investigation of efficiency and practicability. Wound Repair Regen (2007) 1.58
MCA1 and MCA2 that mediate Ca2+ uptake have distinct and overlapping roles in Arabidopsis. Plant Physiol (2010) 1.58
mtDNA lineage expansions in Sherpa population suggest adaptive evolution in Tibetan highlands. Mol Biol Evol (2013) 1.57
Seizures in extremely low birth weight infants are associated with adverse outcome. J Pediatr (2010) 1.56
Genome-wide mapping of the HY5-mediated gene networks in Arabidopsis that involve both transcriptional and post-transcriptional regulation. Plant J (2010) 1.53
The SH3 domain--a family of versatile peptide- and protein-recognition module. Front Biosci (2008) 1.52
HMGB1, a potent proinflammatory cytokine in sepsis. Cytokine (2010) 1.49
Human XPA and RPA DNA repair proteins participate in specific recognition of triplex-induced helical distortions. Proc Natl Acad Sci U S A (2002) 1.49
Effect of an acute mechanical stimulus on aortic structure in the transverse aortic constriction mouse model. Clin Exp Pharmacol Physiol (2011) 1.47
TGF-β-induced epithelial-mesenchymal transition of A549 lung adenocarcinoma cells is enhanced by pro-inflammatory cytokines derived from RAW 264.7 macrophage cells. J Biochem (2011) 1.46
Introduction of human β-defensin-3 into cultured human keratinocytes and fibroblasts by infection of a recombinant adenovirus vector. Burns (2010) 1.45
Adenovirus-mediated overexpression of the activin betaC subunit accelerates liver regeneration in partially hepatectomized rats. J Hepatol (2005) 1.45
Cellular localization and role of kinase activity of PMK1 in Magnaporthe grisea. Eukaryot Cell (2004) 1.44
A genome-wide transcription analysis reveals a close correlation of promoter INDEL polymorphism and heterotic gene expression in rice hybrids. Mol Plant (2008) 1.44
Effect of airborne contaminants on the wettability of supported graphene and graphite. Nat Mater (2013) 1.42
In vitro bacterial polysaccharide biosynthesis: defining the functions of Wzy and Wzz. Nat Chem Biol (2010) 1.41
Physiologic roles of 11beta-hydroxysteroid dehydrogenase type 2 in kidney. Metabolism (2006) 1.40
Designed ATRA analogue active against ATRA-resistant acute promyelocytic leukemia cells having a single nucleotide substitution in their retinoic acid receptor. Leuk Res (2006) 1.40
Association of genetic polymorphisms in the fibrinogen and platelet glycoprotein genes with unstable angina in Chinese patients. Clin Cardiol (2004) 1.39
In vitro transdifferentiation of mature hepatocytes into insulin-producing cells. Endocr J (2006) 1.39
Cut-offs for screening prolonged QT intervals from Fridericia's formula in children and adolescents. Circ J (2010) 1.38
Toward the synthesis of wafer-scale single-crystal graphene on copper foils. ACS Nano (2012) 1.37
Picomolar inhibitors as transition-state probes of 5'-methylthioadenosine nucleosidases. ACS Chem Biol (2007) 1.37
Rif1 provides a new DNA-binding interface for the Bloom syndrome complex to maintain normal replication. EMBO J (2010) 1.36
Detection of differentially expressed microRNAs in serum of pancreatic ductal adenocarcinoma patients: miR-196a could be a potential marker for poor prognosis. Dig Dis Sci (2010) 1.35
MafA regulates expression of genes important to islet beta-cell function. Mol Endocrinol (2007) 1.35
Brassinosteroids control male fertility by regulating the expression of key genes involved in Arabidopsis anther and pollen development. Proc Natl Acad Sci U S A (2010) 1.35
Monitoring county-level vaccination coverage during the 2004-2005 influenza season. Am J Prev Med (2006) 1.34
Proteomic analyses of Oryza sativa mature pollen reveal novel proteins associated with pollen germination and tube growth. Proteomics (2006) 1.33
Functional analysis of the validamycin biosynthetic gene cluster and engineered production of validoxylamine A. Chem Biol (2006) 1.33
Maternally derived FILIA-MATER complex localizes asymmetrically in cleavage-stage mouse embryos. Development (2007) 1.32
WASH inhibits autophagy through suppression of Beclin 1 ubiquitination. EMBO J (2013) 1.32
Gene cluster responsible for validamycin biosynthesis in Streptomyces hygroscopicus subsp. jinggangensis 5008. Appl Environ Microbiol (2005) 1.31
Bifurcation of Arabidopsis NLR immune signaling via Ca²⁺-dependent protein kinases. PLoS Pathog (2013) 1.30
NMPP: a user-customized NimbleGen microarray data processing pipeline. Bioinformatics (2006) 1.30
Frodo links Dishevelled to the p120-catenin/Kaiso pathway: distinct catenin subfamilies promote Wnt signals. Dev Cell (2006) 1.30
4,4'-Di-3-pyridyl-2,2'-dithio-dipyrimidine. Acta Crystallogr Sect E Struct Rep Online (2009) 1.29
Third-generation immucillins: syntheses and bioactivities of acyclic immucillin inhibitors of human purine nucleoside phosphorylase. J Med Chem (2009) 1.29
Inflammatory stimuli from macrophages and cancer cells synergistically promote tumor growth and angiogenesis. Cancer Sci (2007) 1.28
Dual neuroprotective signaling mediated by downregulating two distinct phosphatase activities of PTEN. J Neurosci (2004) 1.28
ASC-J9 suppresses castration-resistant prostate cancer growth through degradation of full-length and splice variant androgen receptors. Neoplasia (2012) 1.28
Engineered proteins detect spontaneous DNA breakage in human and bacterial cells. Elife (2013) 1.28
Enhanced expression of Nrf2 in mice attenuates the fatty liver produced by a methionine- and choline-deficient diet. Toxicol Appl Pharmacol (2010) 1.26
Double-strand breaks induce homologous recombinational repair of interstrand cross-links via cooperation of MSH2, ERCC1-XPF, REV3, and the Fanconi anemia pathway. DNA Repair (Amst) (2007) 1.26
Activin A and betacellulin: effect on regeneration of pancreatic beta-cells in neonatal streptozotocin-treated rats. Diabetes (2004) 1.26
BRAFV600E promotes invasiveness of thyroid cancer cells through nuclear factor kappaB activation. Endocrinology (2006) 1.25
Fanconi anemia (FA) binding protein FAAP20 stabilizes FA complementation group A (FANCA) and participates in interstrand cross-link repair. Proc Natl Acad Sci U S A (2012) 1.25
An approach to studying lung cancer-related proteins in human blood. Mol Cell Proteomics (2005) 1.25
Selective recruitment of TAFs by yeast upstream activating sequences. Implications for eukaryotic promoter structure. Curr Biol (2002) 1.25
Evolutionary expansion, gene structure, and expression of the rice wall-associated kinase gene family. Plant Physiol (2005) 1.24
CDDO-Im protects from acetaminophen hepatotoxicity through induction of Nrf2-dependent genes. Toxicol Appl Pharmacol (2009) 1.23
Targeting the androgen receptor with siRNA promotes prostate cancer metastasis through enhanced macrophage recruitment via CCL2/CCR2-induced STAT3 activation. EMBO Mol Med (2013) 1.23
Differential androgen deprivation therapies with anti-androgens casodex/bicalutamide or MDV3100/Enzalutamide versus anti-androgen receptor ASC-J9(R) Lead to promotion versus suppression of prostate cancer metastasis. J Biol Chem (2013) 1.23
Qiliqiangxin inhibits the development of cardiac hypertrophy, remodeling, and dysfunction during 4 weeks of pressure overload in mice. J Cardiovasc Pharmacol (2012) 1.22
Genetic etiology study of the non-syndromic deafness in Chinese Hans by targeted next-generation sequencing. Orphanet J Rare Dis (2013) 1.22