Published in Neuron on September 30, 2004
Theta Burst TMS as a Tool to Change Smoking Behavior | NCT02939339
Cortical rTMS as a Tool to Change Brain Reactivity to Alcohol Cues (ARC4) | NCT02939313
Glutamate receptor ion channels: structure, regulation, and function. Pharmacol Rev (2010) 11.25
FMRP stalls ribosomal translocation on mRNAs linked to synaptic function and autism. Cell (2011) 8.46
Central sensitization: a generator of pain hypersensitivity by central neural plasticity. J Pain (2009) 7.11
The self-tuning neuron: synaptic scaling of excitatory synapses. Cell (2008) 7.06
A critical period for enhanced synaptic plasticity in newly generated neurons of the adult brain. Neuron (2007) 5.31
Soluble oligomers of the amyloid beta-protein impair synaptic plasticity and behavior. Behav Brain Res (2008) 5.29
mTOR signaling: at the crossroads of plasticity, memory and disease. Trends Neurosci (2009) 5.04
Translational control of long-lasting synaptic plasticity and memory. Neuron (2009) 4.77
Locally dynamic synaptic learning rules in pyramidal neuron dendrites. Nature (2007) 4.48
Caspase-3 activation via mitochondria is required for long-term depression and AMPA receptor internalization. Cell (2010) 4.15
Striatal plasticity and basal ganglia circuit function. Neuron (2008) 3.89
Activation of CaMKII in single dendritic spines during long-term potentiation. Nature (2009) 3.76
Superresolution imaging of chemical synapses in the brain. Neuron (2010) 3.51
N-Acetylcysteine reverses cocaine-induced metaplasticity. Nat Neurosci (2009) 3.49
Cell adhesion molecules: signalling functions at the synapse. Nat Rev Neurosci (2007) 3.47
Abeta plaques lead to aberrant regulation of calcium homeostasis in vivo resulting in structural and functional disruption of neuronal networks. Neuron (2008) 3.46
Reversing EphB2 depletion rescues cognitive functions in Alzheimer model. Nature (2010) 3.36
Regulation of NMDA receptor subunit expression and its implications for LTD, LTP, and metaplasticity. Neuropharmacology (2008) 3.30
Affective neuroscience of pleasure: reward in humans and animals. Psychopharmacology (Berl) (2008) 3.26
Rapid neocortical dynamics: cellular and network mechanisms. Neuron (2009) 3.06
Glutamatergic substrates of drug addiction and alcoholism. Biochem Pharmacol (2007) 3.06
Two coincidence detectors for spike timing-dependent plasticity in somatosensory cortex. J Neurosci (2006) 3.00
BDNF: a key regulator for protein synthesis-dependent LTP and long-term memory? Neurobiol Learn Mem (2007) 2.96
TRPV1 channels mediate long-term depression at synapses on hippocampal interneurons. Neuron (2008) 2.94
Synaptic mechanisms for plasticity in neocortex. Annu Rev Neurosci (2009) 2.89
Modulating parameters of excitability during and after transcranial direct current stimulation of the human motor cortex. J Physiol (2005) 2.89
The spread of Ras activity triggered by activation of a single dendritic spine. Science (2008) 2.87
Neuromodulators control the polarity of spike-timing-dependent synaptic plasticity. Neuron (2007) 2.86
Unraveling mechanisms of homeostatic synaptic plasticity. Neuron (2010) 2.85
Neuroplasticity in the mesolimbic dopamine system and cocaine addiction. Br J Pharmacol (2008) 2.83
Reward-predictive cues enhance excitatory synaptic strength onto midbrain dopamine neurons. Science (2008) 2.82
Organelles and trafficking machinery for postsynaptic plasticity. Annu Rev Neurosci (2006) 2.82
The expanding social network of ionotropic glutamate receptors: TARPs and other transmembrane auxiliary subunits. Neuron (2011) 2.82
AMPARs and synaptic plasticity: the last 25 years. Neuron (2013) 2.80
Connectivity reflects coding: a model of voltage-based STDP with homeostasis. Nat Neurosci (2010) 2.78
Diffusional trapping of GluR1 AMPA receptors by input-specific synaptic activity. Neuron (2007) 2.74
Homeostatic synaptic plasticity: local and global mechanisms for stabilizing neuronal function. Cold Spring Harb Perspect Biol (2012) 2.68
LTP requires a reserve pool of glutamate receptors independent of subunit type. Nature (2012) 2.59
PSD-95 is required for activity-driven synapse stabilization. Proc Natl Acad Sci U S A (2007) 2.56
Supramolecular assemblies and localized regulation of voltage-gated ion channels. Physiol Rev (2009) 2.53
Postsynaptic TRPV1 triggers cell type-specific long-term depression in the nucleus accumbens. Nat Neurosci (2010) 2.40
Persistence of experience-induced homeostatic synaptic plasticity through adulthood in superficial layers of mouse visual cortex. J Neurosci (2007) 2.38
Multiple modes of network homeostasis in visual cortical layer 2/3. J Neurosci (2008) 2.31
Endocytic trafficking and recycling maintain a pool of mobile surface AMPA receptors required for synaptic potentiation. Neuron (2009) 2.27
Structural and molecular remodeling of dendritic spine substructures during long-term potentiation. Neuron (2014) 2.27
Activity-dependent neuronal signalling and autism spectrum disorder. Nature (2013) 2.23
Postsynaptic BDNF-TrkB signaling in synapse maturation, plasticity, and disease. Dev Neurobiol (2010) 2.19
Forniceal deep brain stimulation rescues hippocampal memory in Rett syndrome mice. Nature (2015) 2.18
Molecular dissociation of the role of PSD-95 in regulating synaptic strength and LTD. Neuron (2008) 2.15
Mechanism and time course of cocaine-induced long-term potentiation in the ventral tegmental area. J Neurosci (2008) 2.15
Bidirectional modulation of incubation of cocaine craving by silent synapse-based remodeling of prefrontal cortex to accumbens projections. Neuron (2014) 2.14
Single-molecule discrimination of discrete perisynaptic and distributed sites of actin filament assembly within dendritic spines. Neuron (2010) 2.12
New medications for drug addiction hiding in glutamatergic neuroplasticity. Mol Psychiatry (2011) 2.11
Fragile X mental retardation protein deficiency leads to excessive mGluR5-dependent internalization of AMPA receptors. Proc Natl Acad Sci U S A (2007) 2.10
Phospholipase A2 reduction ameliorates cognitive deficits in a mouse model of Alzheimer's disease. Nat Neurosci (2008) 2.09
TRPV1 activation by endogenous anandamide triggers postsynaptic long-term depression in dentate gyrus. Nat Neurosci (2010) 2.06
Nonapoptotic function of BAD and BAX in long-term depression of synaptic transmission. Neuron (2011) 2.06
Distributed synergistic plasticity and cerebellar learning. Nat Rev Neurosci (2012) 2.04
Cellular neuroadaptations to chronic opioids: tolerance, withdrawal and addiction. Br J Pharmacol (2008) 1.99
Loss of GluN2B-containing NMDA receptors in CA1 hippocampus and cortex impairs long-term depression, reduces dendritic spine density, and disrupts learning. J Neurosci (2010) 1.99
Principles of long-term dynamics of dendritic spines. J Neurosci (2008) 1.96
Synaptic scaling requires the GluR2 subunit of the AMPA receptor. J Neurosci (2009) 1.95
Obesity and hypertriglyceridemia produce cognitive impairment. Endocrinology (2008) 1.94
Ubiquitination in postsynaptic function and plasticity. Annu Rev Cell Dev Biol (2010) 1.94
Fragile X protein FMRP is required for homeostatic plasticity and regulation of synaptic strength by retinoic acid. J Neurosci (2010) 1.92
Deprivation-induced synaptic depression by distinct mechanisms in different layers of mouse visual cortex. Proc Natl Acad Sci U S A (2007) 1.92
A burst-based "Hebbian" learning rule at retinogeniculate synapses links retinal waves to activity-dependent refinement. PLoS Biol (2007) 1.89
Glial cells in (patho)physiology. J Neurochem (2012) 1.89
Age-dependent requirement of AKAP150-anchored PKA and GluR2-lacking AMPA receptors in LTP. EMBO J (2007) 1.88
Corticostriatal and thalamostriatal synapses have distinctive properties. J Neurosci (2008) 1.86
Autonomous CaMKII can promote either long-term potentiation or long-term depression, depending on the state of T305/T306 phosphorylation. J Neurosci (2010) 1.85
Neto1 is a novel CUB-domain NMDA receptor-interacting protein required for synaptic plasticity and learning. PLoS Biol (2009) 1.85
A GluR1-cGKII interaction regulates AMPA receptor trafficking. Neuron (2007) 1.83
Bidirectional synaptic mechanisms of ocular dominance plasticity in visual cortex. Philos Trans R Soc Lond B Biol Sci (2009) 1.83
Long-term potentiation selectively expressed by NMDA receptors at hippocampal mossy fiber synapses. Neuron (2008) 1.83
An essential role for PICK1 in NMDA receptor-dependent bidirectional synaptic plasticity. Neuron (2008) 1.82
Developmental switch in the contribution of presynaptic and postsynaptic NMDA receptors to long-term depression. J Neurosci (2007) 1.81
A critical role for PSD-95/AKAP interactions in endocytosis of synaptic AMPA receptors. Nat Neurosci (2009) 1.80
Synapse elimination and learning rules co-regulated by MHC class I H2-Db. Nature (2014) 1.78
Distinct modes of AMPA receptor suppression at developing synapses by GluN2A and GluN2B: single-cell NMDA receptor subunit deletion in vivo. Neuron (2011) 1.78
Relapse induced by cues predicting cocaine depends on rapid, transient synaptic potentiation. Neuron (2013) 1.78
Brain cholesterol turnover required for geranylgeraniol production and learning in mice. Proc Natl Acad Sci U S A (2006) 1.77
Compartmentalized versus global synaptic plasticity on dendrites controlled by experience. Neuron (2011) 1.76
Extinction training after cocaine self-administration induces glutamatergic plasticity to inhibit cocaine seeking. J Neurosci (2010) 1.76
The dendritic branch is the preferred integrative unit for protein synthesis-dependent LTP. Neuron (2011) 1.75
Metaplasticity at single glutamatergic synapses. Neuron (2010) 1.74
Direct evidence for wake-related increases and sleep-related decreases in synaptic strength in rodent cortex. J Neurosci (2010) 1.74
The immune protein CD3zeta is required for normal development of neural circuits in the retina. Neuron (2010) 1.74
Activity-dependent regulation of synapses by retrograde messengers. Neuron (2009) 1.73
Alzheimer's disease: synaptic dysfunction and Abeta. Mol Neurodegener (2009) 1.73
Hippocampal synaptic plasticity and spatial learning are impaired in a rat model of sleep fragmentation. Eur J Neurosci (2006) 1.70
New insights into the role of brain-derived neurotrophic factor in synaptic plasticity. Mol Cell Neurosci (2009) 1.69
Sleep homeostasis and cortical synchronization: II. A local field potential study of sleep slow waves in the rat. Sleep (2007) 1.67
NMDA receptor-dependent long-term potentiation and long-term depression (LTP/LTD). Cold Spring Harb Perspect Biol (2012) 1.67
Metabotropic glutamate receptor ligands as potential therapeutics for addiction. Curr Drug Abuse Rev (2009) 1.66
Distinct roles of NR2A and NR2B cytoplasmic tails in long-term potentiation. J Neurosci (2010) 1.65
CaMKII binding to GluN2B is critical during memory consolidation. EMBO J (2012) 1.62
Synaptic plasticity and phosphorylation. Pharmacol Ther (2006) 1.58
Synapses and Alzheimer's disease. Cold Spring Harb Perspect Biol (2012) 1.57
Understanding LTP in pain pathways. Mol Pain (2007) 1.56
Learning induces long-term potentiation in the hippocampus. Science (2006) 7.46
Correction of fragile X syndrome in mice. Neuron (2007) 6.51
Altered synaptic plasticity in a mouse model of fragile X mental retardation. Proc Natl Acad Sci U S A (2002) 6.45
Chronic pharmacological mGlu5 inhibition corrects fragile X in adult mice. Neuron (2012) 4.31
Mutations causing syndromic autism define an axis of synaptic pathophysiology. Nature (2011) 4.13
The autistic neuron: troubled translation? Cell (2008) 3.81
NMDA receptor-dependent ocular dominance plasticity in adult visual cortex. Neuron (2003) 3.79
Ubiquitination regulates PSD-95 degradation and AMPA receptor surface expression. Neuron (2003) 3.62
How monocular deprivation shifts ocular dominance in visual cortex of young mice. Neuron (2004) 3.43
Reward timing in the primary visual cortex. Science (2006) 3.36
Molecular mechanism for loss of visual cortical responsiveness following brief monocular deprivation. Nat Neurosci (2003) 2.81
Effects of STX209 (arbaclofen) on neurobehavioral function in children and adults with fragile X syndrome: a randomized, controlled, phase 2 trial. Sci Transl Med (2012) 2.51
A unified model of NMDA receptor-dependent bidirectional synaptic plasticity. Proc Natl Acad Sci U S A (2002) 2.45
Synaptic dysfunction in neurodevelopmental disorders associated with autism and intellectual disabilities. Cold Spring Harb Perspect Biol (2012) 2.42
Hypersensitivity to mGluR5 and ERK1/2 leads to excessive protein synthesis in the hippocampus of a mouse model of fragile X syndrome. J Neurosci (2010) 2.42
Smaller dendritic spines, weaker synaptic transmission, but enhanced spatial learning in mice lacking Shank1. J Neurosci (2008) 2.27
New views of Arc, a master regulator of synaptic plasticity. Nat Neurosci (2011) 2.18
The pathophysiology of fragile X (and what it teaches us about synapses). Annu Rev Neurosci (2012) 2.16
Instructive effect of visual experience in mouse visual cortex. Neuron (2006) 2.12
Activation of NR2B-containing NMDA receptors is not required for NMDA receptor-dependent long-term depression. Neuropharmacology (2006) 2.10
Role for metabotropic glutamate receptor 5 (mGluR5) in the pathogenesis of fragile X syndrome. J Physiol (2008) 2.08
Extracellular signal-regulated protein kinase activation is required for metabotropic glutamate receptor-dependent long-term depression in hippocampal area CA1. J Neurosci (2004) 2.06
Lovastatin corrects excess protein synthesis and prevents epileptogenesis in a mouse model of fragile X syndrome. Neuron (2013) 2.00
Toward fulfilling the promise of molecular medicine in fragile X syndrome. Annu Rev Med (2011) 1.96
Deprivation-induced synaptic depression by distinct mechanisms in different layers of mouse visual cortex. Proc Natl Acad Sci U S A (2007) 1.92
Bidirectional synaptic mechanisms of ocular dominance plasticity in visual cortex. Philos Trans R Soc Lond B Biol Sci (2009) 1.83
Obligatory role of NR2A for metaplasticity in visual cortex. Neuron (2007) 1.72
Reversal of disease-related pathologies in the fragile X mouse model by selective activation of GABAB receptors with arbaclofen. Sci Transl Med (2012) 1.72
Mechanism-based approaches to treating fragile X. Pharmacol Ther (2010) 1.49
Loss of Arc renders the visual cortex impervious to the effects of sensory experience or deprivation. Nat Neurosci (2010) 1.48
A morphological correlate of synaptic scaling in visual cortex. J Neurosci (2004) 1.48
Visual experience induces long-term potentiation in the primary visual cortex. J Neurosci (2010) 1.43
Translating glutamate: from pathophysiology to treatment. Sci Transl Med (2011) 1.42
Evidence for altered NMDA receptor function as a basis for metaplasticity in visual cortex. J Neurosci (2003) 1.41
A cholinergic mechanism for reward timing within primary visual cortex. Neuron (2013) 1.29
Essential role for a long-term depression mechanism in ocular dominance plasticity. Proc Natl Acad Sci U S A (2009) 1.26
Cognitive dysfunction and prefrontal synaptic abnormalities in a mouse model of fragile X syndrome. Proc Natl Acad Sci U S A (2011) 1.26
The ratio of NR2A/B NMDA receptor subunits determines the qualities of ocular dominance plasticity in visual cortex. Proc Natl Acad Sci U S A (2009) 1.26
Cannabinoid receptor blockade reveals parallel plasticity mechanisms in different layers of mouse visual cortex. Neuron (2008) 1.25
Activity-dependent regulation of NR2B translation contributes to metaplasticity in mouse visual cortex. Neuropharmacology (2006) 1.20
Pharmacological reversal of synaptic plasticity deficits in the mouse model of fragile X syndrome by group II mGluR antagonist or lithium treatment. Brain Res (2010) 1.14
Fragile X mental retardation protein and synaptic plasticity. Mol Brain (2013) 1.12
Learning reward timing in cortex through reward dependent expression of synaptic plasticity. Proc Natl Acad Sci U S A (2009) 1.12
Relative contribution of feedforward excitatory connections to expression of ocular dominance plasticity in layer 4 of visual cortex. Neuron (2010) 1.10
The BCM theory of synapse modification at 30: interaction of theory with experiment. Nat Rev Neurosci (2012) 1.08
Bidirectional modifications of visual acuity induced by monocular deprivation in juvenile and adult rats. J Neurosci (2006) 1.07
Significance of N-methyl-D-aspartate (NMDA) receptor-mediated signaling in human keratinocytes. J Cell Physiol (2004) 1.07
Thalamic activity that drives visual cortical plasticity. Nat Neurosci (2009) 1.06
STX209 (arbaclofen) for autism spectrum disorders: an 8-week open-label study. J Autism Dev Disord (2014) 1.02
Rapid structural remodeling of thalamocortical synapses parallels experience-dependent functional plasticity in mouse primary visual cortex. J Neurosci (2010) 1.01
The effects of L-amphetamine sulfate on cognition in MS patients: results of a randomized controlled trial. J Neurol (2009) 0.99
Group I metabotropic glutamate receptors: a role in neurodevelopmental disorders? Mol Neurobiol (2007) 0.99
Fragile x syndrome and autism: from disease model to therapeutic targets. J Neurodev Disord (2009) 0.98
A biophysically-based neuromorphic model of spike rate- and timing-dependent plasticity. Proc Natl Acad Sci U S A (2011) 0.97
Loss of the fragile X mental retardation protein decouples metabotropic glutamate receptor dependent priming of long-term potentiation from protein synthesis. J Neurophysiol (2010) 0.96
Stimulus-selective response plasticity in the visual cortex: an assay for the assessment of pathophysiology and treatment of cognitive impairment associated with psychiatric disorders. Biol Psychiatry (2011) 0.95
Recovery from monocular deprivation using binocular deprivation. J Neurophysiol (2008) 0.95
How the mechanisms of long-term synaptic potentiation and depression serve experience-dependent plasticity in primary visual cortex. Philos Trans R Soc Lond B Biol Sci (2013) 0.94
Stimulus for rapid ocular dominance plasticity in visual cortex. J Neurophysiol (2006) 0.92
Bidirectional ocular dominance plasticity of inhibitory networks: recent advances and unresolved questions. Front Cell Neurosci (2010) 0.89
Is metabotropic glutamate receptor 5 upregulated in prefrontal cortex in fragile X syndrome? Mol Autism (2013) 0.86
Promoting neurological recovery of function via metaplasticity. Future Neurol (2010) 0.86
Activation of mGluR5 induces rapid and long-lasting protein kinase D phosphorylation in hippocampal neurons. J Mol Neurosci (2010) 0.85
Activity-dependent NR2B expression is mediated by MeCP2-dependent epigenetic regulation. Biochem Biophys Res Commun (2008) 0.85
Courting a cure for fragile X. Neuron (2005) 0.83
The levo enantiomer of amphetamine increases memory consolidation and gene expression in the hippocampus without producing locomotor stimulation. Neurobiol Learn Mem (2009) 0.82
Lifting the mood on treating fragile X. Biol Psychiatry (2012) 0.78
Synaptic plasticity in an altered state. Neuron (2002) 0.75
Erratum: Visual recognition memory, manifested as long-term habituation, requires synaptic plasticity in V1. Nat Neurosci (2015) 0.75