Published in Nutrition on October 01, 2004
Lipotoxicity in the heart. Biochim Biophys Acta (2009) 1.60
Examination of 'lipotoxicity' in skeletal muscle of high-fat fed and ob/ob mice. J Physiol (2009) 1.13
Increased propensity for cell death in diabetic human heart is mediated by mitochondrial-dependent pathways. Am J Physiol Heart Circ Physiol (2010) 1.03
Autophagy contributes to retardation of cardiac growth in diabetic rats. Lab Anim Res (2012) 0.84
Unbreak my heart: targeting mitochondrial autophagy in diabetic cardiomyopathy. Antioxid Redox Signal (2015) 0.81
DPP-4 inhibition improves early mortality, β cell function, and adipose tissue inflammation in db/db mice fed a diet containing sucrose and linoleic acid. Diabetol Metab Syndr (2016) 0.78
The role of dietary fatty acids in predicting myocardial structure in fat-fed rats. Lipids Health Dis (2011) 0.77
Beta-cell ABCA1 influences insulin secretion, glucose homeostasis and response to thiazolidinedione treatment. Nat Med (2007) 3.53
Brown adipose tissue regulates glucose homeostasis and insulin sensitivity. J Clin Invest (2012) 3.33
Short communication: ischemia/reperfusion tolerance is time-of-day-dependent: mediation by the cardiomyocyte circadian clock. Circ Res (2009) 2.38
Discovery of TBC1D1 as an insulin-, AICAR-, and contraction-stimulated signaling nexus in mouse skeletal muscle. J Biol Chem (2008) 2.09
Role of changes in cardiac metabolism in development of diabetic cardiomyopathy. Am J Physiol Heart Circ Physiol (2006) 1.97
Single phosphorylation sites in Acc1 and Acc2 regulate lipid homeostasis and the insulin-sensitizing effects of metformin. Nat Med (2013) 1.91
DNA methylation potential: dietary intake and blood concentrations of one-carbon metabolites and cofactors in rural African women. Am J Clin Nutr (2013) 1.88
Adipose triglyceride lipase deficiency causes tissue-specific changes in insulin signaling. J Biol Chem (2009) 1.63
Adipose-specific deletion of TFAM increases mitochondrial oxidation and protects mice against obesity and insulin resistance. Cell Metab (2012) 1.32
Glucocorticoids produce whole body insulin resistance with changes in cardiac metabolism. Am J Physiol Endocrinol Metab (2006) 1.31
Monosaccharide-induced lipogenesis regulates the human hepatic sex hormone-binding globulin gene. J Clin Invest (2007) 1.26
Direct regulation of myocardial triglyceride metabolism by the cardiomyocyte circadian clock. J Biol Chem (2009) 1.24
Decreasing linoleic acid with constant alpha-linolenic acid in dietary fats increases (n-3) eicosapentaenoic acid in plasma phospholipids in healthy men. J Nutr (2007) 1.21
Gene knockout of Acc2 has little effect on body weight, fat mass, or food intake. Proc Natl Acad Sci U S A (2010) 1.18
Hypermethylation of Fads2 and altered hepatic fatty acid and phospholipid metabolism in mice with hyperhomocysteinemia. J Biol Chem (2007) 1.18
A small molecule AMPK activator protects the heart against ischemia-reperfusion injury. J Mol Cell Cardiol (2011) 1.15
Cardiomyocyte apoptosis induced by short-term diabetes requires mitochondrial GSH depletion. Am J Physiol Heart Circ Physiol (2005) 1.14
Myocardial ATGL overexpression decreases the reliance on fatty acid oxidation and protects against pressure overload-induced cardiac dysfunction. Mol Cell Biol (2011) 1.13
Neuronal protein tyrosine phosphatase 1B deficiency results in inhibition of hypothalamic AMPK and isoform-specific activation of AMPK in peripheral tissues. Mol Cell Biol (2009) 1.12
Maternal dietary (n-3) fatty acid deficiency alters neurogenesis in the embryonic rat brain. J Nutr (2006) 1.11
Contraction regulates site-specific phosphorylation of TBC1D1 in skeletal muscle. Biochem J (2010) 1.10
Identification of a novel phosphorylation site on TBC1D4 regulated by AMP-activated protein kinase in skeletal muscle. Am J Physiol Cell Physiol (2009) 1.09
AMP-activated protein kinase confers protection against TNF-{alpha}-induced cardiac cell death. Cardiovasc Res (2009) 1.09
Skeletal muscle triacylglycerol hydrolysis does not influence metabolic complications of obesity. Diabetes (2013) 1.06
Trans fatty acids in human milk in Canada declined with the introduction of trans fat food labeling. J Nutr (2006) 1.06
Phthalate metabolites in urine of CF patients are associated with use of enteric-coated pancreatic enzymes. Environ Toxicol Pharmacol (2009) 1.06
Exercise increases TBC1D1 phosphorylation in human skeletal muscle. Am J Physiol Endocrinol Metab (2011) 1.04
Linoleic acid is associated with lower long-chain n-6 and n-3 fatty acids in red blood cell lipids of Canadian pregnant women. Am J Clin Nutr (2009) 1.04
Pyruvate dehydrogenase and the regulation of glucose oxidation in hypertrophied rat hearts. Cardiovasc Res (2002) 1.03
Early second trimester maternal plasma choline and betaine are related to measures of early cognitive development in term infants. PLoS One (2012) 1.00
High dietary omega-6 fatty acids contribute to reduced docosahexaenoic acid in the developing brain and inhibit secondary neurite growth. Brain Res (2008) 0.99
Hyperglycemia-induced protein kinase C β2 activation induces diastolic cardiac dysfunction in diabetic rats by impairing caveolin-3 expression and Akt/eNOS signaling. Diabetes (2013) 0.98
Myo1c regulates glucose uptake in mouse skeletal muscle. J Biol Chem (2010) 0.97
Myocardial triacylglycerol metabolism. J Mol Cell Cardiol (2012) 0.97
FoxO1 is crucial for sustaining cardiomyocyte metabolism and cell survival. Cardiovasc Res (2012) 0.96
Cardiomyocyte ATP production, metabolic flexibility, and survival require calcium flux through cardiac ryanodine receptors in vivo. J Biol Chem (2013) 0.96
Relationship of dimethylglycine, choline, and betaine with oxoproline in plasma of pregnant women and their newborn infants. J Nutr (2007) 0.95
AMPK phosphorylation of ACC2 is required for skeletal muscle fatty acid oxidation and insulin sensitivity in mice. Diabetologia (2014) 0.95
Induction of mitochondrial nitrative damage and cardiac dysfunction by chronic provision of dietary omega-6 polyunsaturated fatty acids. Free Radic Biol Med (2006) 0.94
Controversial nutrients that potentially affect preterm neurodevelopment: essential fatty acids and iron. Pediatr Res (2005) 0.94
Single-dose dexamethasone induces whole-body insulin resistance and alters both cardiac fatty acid and carbohydrate metabolism. Diabetes (2004) 0.94
Cardiac triglyceride accumulation following acute lipid excess occurs through activation of a FoxO1-iNOS-CD36 pathway. Free Radic Biol Med (2011) 0.93
The increase in cardiac pyruvate dehydrogenase kinase-4 after short-term dexamethasone is controlled by an Akt-p38-forkhead box other factor-1 signaling axis. Endocrinology (2010) 0.93
TLR4 regulates cardiac lipid accumulation and diabetic heart disease in the nonobese diabetic mouse model of type 1 diabetes. Am J Physiol Heart Circ Physiol (2012) 0.92
Cardiac lipoprotein lipase: metabolic basis for diabetic heart disease. Cardiovasc Res (2005) 0.92
Phosphatidylcholine and lysophosphatidylcholine excretion is increased in children with cystic fibrosis and is associated with plasma homocysteine, S-adenosylhomocysteine, and S-adenosylmethionine. Am J Clin Nutr (2005) 0.92
Low fish intake is associated with low blood concentrations of vitamin D, choline and n-3 DHA in pregnant women. Br J Nutr (2012) 0.91
Increased mitochondrial activity in BMP7-treated brown adipocytes, due to increased CPT1- and CD36-mediated fatty acid uptake. Antioxid Redox Signal (2012) 0.90
Cardiac cell death in early diabetes and its modulation by dietary fatty acids. Biochim Biophys Acta (2006) 0.89
Cardiac proinflammatory pathways are altered with different dietary n-6 linoleic to n-3 alpha-linolenic acid ratios in normal, fat-fed pigs. Am J Physiol Heart Circ Physiol (2007) 0.89
A role for hepatic leptin signaling in lipid metabolism via altered very low density lipoprotein composition and liver lipase activity in mice. Hepatology (2012) 0.89
Adiponectin increases LPL activity via RhoA/ROCK-mediated actin remodelling in adult rat cardiomyocytes. Endocrinology (2010) 0.88
AMPK control of myocardial fatty acid metabolism fluctuates with the intensity of insulin-deficient diabetes. J Mol Cell Cardiol (2006) 0.88
Dietary oils modify the host immune response and colonic tissue damage following Citrobacter rodentium infection in mice. Am J Physiol Gastrointest Liver Physiol (2013) 0.88
The metabolic "switch" AMPK regulates cardiac heparin-releasable lipoprotein lipase. Am J Physiol Endocrinol Metab (2004) 0.87
Acute diabetes moderates trafficking of cardiac lipoprotein lipase through p38 mitogen-activated protein kinase-dependent actin cytoskeleton organization. Diabetes (2007) 0.87
Predictors and outcomes of household food insecurity among inner city families with preschool children in Vancouver. Can J Public Health (2006) 0.86
Omega-3 fatty acids can reverse the long-term deficits in hippocampal synaptic plasticity caused by prenatal ethanol exposure. Neurosci Lett (2013) 0.86
Bakery foods are the major dietary source of trans-fatty acids among pregnant women with diets providing 30 percent energy from fat. J Am Diet Assoc (2002) 0.86
Suboptimal vitamin D levels in pregnant women despite supplement use. Can J Public Health (2011) 0.86
Early structural and metabolic cardiac remodelling in response to inducible adipose triglyceride lipase ablation. Cardiovasc Res (2013) 0.86
Protein kinase D is a key regulator of cardiomyocyte lipoprotein lipase secretion after diabetes. Circ Res (2008) 0.86
Inhibition of beta-cell sodium-calcium exchange enhances glucose-dependent elevations in cytoplasmic calcium and insulin secretion. Diabetes (2010) 0.86
The vestigial enzyme D-dopachrome tautomerase protects the heart against ischemic injury. J Clin Invest (2014) 0.86
Cleavage of protein kinase D after acute hypoinsulinemia prevents excessive lipoprotein lipase-mediated cardiac triglyceride accumulation. Diabetes (2009) 0.85
Glucose-induced endothelial heparanase secretion requires cortical and stress actin reorganization. Cardiovasc Res (2010) 0.85
Urocortin 2 autocrine/paracrine and pharmacologic effects to activate AMP-activated protein kinase in the heart. Proc Natl Acad Sci U S A (2013) 0.85
Hyperglycemia-induced secretion of endothelial heparanase stimulates a vascular endothelial growth factor autocrine network in cardiomyocytes that promotes recruitment of lipoprotein lipase. Arterioscler Thromb Vasc Biol (2013) 0.85
Cardiac glycogen accumulation after dexamethasone is regulated by AMPK. Am J Physiol Heart Circ Physiol (2008) 0.84
Evidence for rapid "metabolic switching" through lipoprotein lipase occupation of endothelial-binding sites. J Mol Cell Cardiol (2003) 0.84