Published in Clin Cancer Res on October 01, 2004
Growth factor-induced shedding of syndecan-1 confers glypican-1 dependence on mitogenic responses of cancer cells. J Cell Biol (2005) 1.51
Membrane-active host defense peptides--challenges and perspectives for the development of novel anticancer drugs. Chem Phys Lipids (2011) 1.45
Glypican-3: a new target for cancer immunotherapy. Eur J Cancer (2010) 1.30
Syndecan-1: a dynamic regulator of the myeloma microenvironment. Clin Exp Metastasis (2007) 1.27
NFAT promotes carcinoma invasive migration through glypican-6. Biochem J (2011) 1.09
Identification of HLA-A2-restricted CTL epitopes of a novel tumour-associated antigen, KIF20A, overexpressed in pancreatic cancer. Br J Cancer (2010) 1.06
Proteomic expression signature distinguishes cancerous and nonmalignant tissues in hepatocellular carcinoma. J Proteome Res (2009) 1.04
Glypican-3-mediated oncogenesis involves the Insulin-like growth factor-signaling pathway. Carcinogenesis (2008) 1.02
Investigation of the role of glypican 3 in liver regeneration and hepatocyte proliferation. Am J Pathol (2009) 0.97
Immunotherapy targets in pediatric cancer. Front Oncol (2012) 0.97
Aggressive melanoma cells escape from BMP7-mediated autocrine growth inhibition through coordinated Noggin upregulation. Lab Invest (2008) 0.96
GPC5 gene and its related pathways in lung cancer. J Thorac Oncol (2011) 0.92
Small lytic peptides escape the inhibitory effect of heparan sulfate on the surface of cancer cells. BMC Cancer (2011) 0.88
Significant clinical response of progressive recurrent ovarian clear cell carcinoma to glypican-3-derived peptide vaccine therapy: two case reports. Hum Vaccin Immunother (2013) 0.88
Identification of cell surface proteins as potential immunotherapy targets in 12 pediatric cancers. Front Oncol (2012) 0.86
Serum anti-BPAG1 auto-antibody is a novel marker for human melanoma. PLoS One (2010) 0.86
killerFLIP: a novel lytic peptide specifically inducing cancer cell death. Cell Death Dis (2013) 0.83
The oncolytic peptide LTX-315 induces cell death and DAMP release by mitochondria distortion in human melanoma cells. Oncotarget (2015) 0.83
Heparan sulfate proteoglycans and human breast cancer epithelial cell tumorigenicity. J Cell Biochem (2014) 0.82
Surveillance and diagnosis of hepatocellular carcinoma in patients with cirrhosis. World J Hepatol (2009) 0.81
Proteoglycans in liver cancer. World J Gastroenterol (2016) 0.78
Glypican 3 overexpression in primary and metastatic Wilms tumors. Virchows Arch (2014) 0.78
Secreted primary human malignant mesothelioma exosome signature reflects oncogenic cargo. Sci Rep (2016) 0.77
Large-scale expansion of γδ T cells and peptide-specific cytotoxic T cells using zoledronate for adoptive immunotherapy. Int J Oncol (2014) 0.77
GPC3 expression in mouse ovarian cancer induces GPC3‑specific T cell-mediated immune response through M1 macrophages and suppresses tumor growth. Oncol Rep (2014) 0.76
Critical analysis of the potential of targeting GPC3 in hepatocellular carcinoma. J Hepatocell Carcinoma (2014) 0.75
Efficacy of glypican-3-derived peptide vaccine therapy on the survival of patients with refractory ovarian clear cell carcinoma. Oncoimmunology (2016) 0.75
Clinical correlation of calpain-1 and glypican-3 expression with gallbladder carcinoma. Oncol Lett (2016) 0.75
Enhancement of antitumor effect by peptide vaccine therapy in combination with anti-CD4 antibody: Study in a murine model. Biochem Biophys Rep (2016) 0.75
Distinct sets of genetic alterations in melanoma. N Engl J Med (2005) 17.26
Determinants of BRAF mutations in primary melanomas. J Natl Cancer Inst (2003) 3.65
Glypican-3, overexpressed specifically in human hepatocellular carcinoma, is a novel tumor marker. Biochem Biophys Res Commun (2003) 2.78
Inactivation of Drosophila DJ-1 leads to impairments of oxidative stress response and phosphatidylinositol 3-kinase/Akt signaling. Proc Natl Acad Sci U S A (2005) 2.58
Topical drug rescue strategy and skin protection based on the role of Mc1r in UV-induced tanning. Nature (2006) 2.09
UV-induced DNA damage and melanin content in human skin differing in racial/ethnic origin. FASEB J (2003) 1.88
Identification of promiscuous KIF20A long peptides bearing both CD4+ and CD8+ T-cell epitopes: KIF20A-specific CD4+ T-cell immunity in patients with malignant tumor. Clin Cancer Res (2013) 1.87
Advanced chemical methods in melanin determination. Pigment Cell Res (2002) 1.78
Current challenges in understanding melanogenesis: bridging chemistry, biological control, morphology, and function. Pigment Cell Melanoma Res (2009) 1.78
Human high molecular weight-melanoma-associated antigen (HMW-MAA): a melanoma cell surface chondroitin sulfate proteoglycan (MSCP) with biological and clinical significance. Crit Rev Immunol (2004) 1.68
Protection against UVR involves MC1R-mediated non-pigmentary and pigmentary mechanisms in vivo. J Invest Dermatol (2010) 1.65
Identification of HLA-A2- or HLA-A24-restricted CTL epitopes possibly useful for glypican-3-specific immunotherapy of hepatocellular carcinoma. Clin Cancer Res (2006) 1.64
Chemical analysis of late stages of pheomelanogenesis: conversion of dihydrobenzothiazine to a benzothiazole structure. Pigment Cell Melanoma Res (2009) 1.62
Comparison of structural and chemical properties of black and red human hair melanosomes. Photochem Photobiol (2005) 1.54
Chemistry of mixed melanogenesis--pivotal roles of dopaquinone. Photochem Photobiol (2008) 1.47
Serum levels of pigmentation markers are elevated in patients undergoing hemodialysis. Blood Purif (2007) 1.46
Predicting phenotype from genotype: normal pigmentation. J Forensic Sci (2010) 1.43
High ratio of myeloid dendritic cells to plasmacytoid dendritic cells in blood of patients with acute coronary syndrome. Circ J (2009) 1.43
Regulation of human skin pigmentation and responses to ultraviolet radiation. Pigment Cell Res (2007) 1.41
Ion-exchange and adsorption of Fe(III) by Sepia melanin. Pigment Cell Res (2004) 1.32
Mouse homologue of a novel human oncofetal antigen, glypican-3, evokes T-cell-mediated tumor rejection without autoimmune reactions in mice. Clin Cancer Res (2004) 1.32
Usefulness of alkaline hydrogen peroxide oxidation to analyze eumelanin and pheomelanin in various tissue samples: application to chemical analysis of human hair melanins. Pigment Cell Melanoma Res (2011) 1.31
Melanin acts as a potent UVB photosensitizer to cause an atypical mode of cell death in murine skin. Proc Natl Acad Sci U S A (2004) 1.31
Slc7a11 gene controls production of pheomelanin pigment and proliferation of cultured cells. Proc Natl Acad Sci U S A (2005) 1.28
Quantitative analysis of eumelanin and pheomelanin in humans, mice, and other animals: a comparative review. Pigment Cell Res (2003) 1.26
A method to generate antigen-specific mAb capable of staining formalin-fixed, paraffin-embedded tissue sections. J Immunol Methods (2005) 1.25
The structure of neuromelanin as studied by chemical degradative methods. J Neurochem (2003) 1.24
Melanins and melanogenesis: methods, standards, protocols. Pigment Cell Melanoma Res (2013) 1.23
Melanocortin 1 receptor genotype: an important determinant of the damage response of melanocytes to ultraviolet radiation. FASEB J (2010) 1.23
Interaction of Hermansky-Pudlak Syndrome genes in the regulation of lysosome-related organelles. Traffic (2006) 1.23
Strength and cost of an induced immune response are associated with a heritable melanin-based colour trait in female tawny owls. J Anim Ecol (2009) 1.21
Melanin content and MC1R function independently affect UVR-induced DNA damage in cultured human melanocytes. Pigment Cell Res (2006) 1.20
Human melanocortin 1 receptor variants, receptor function and melanocyte response to UV radiation. J Cell Sci (2002) 1.19
Comparisons of the structural and chemical properties of melanosomes isolated from retinal pigment epithelium, iris and choroid of newborn and mature bovine eyes. Photochem Photobiol (2005) 1.18
Galectin-9 in physiological and pathological conditions. Glycoconj J (2004) 1.18
Identification of a novel tumor-associated antigen, cadherin 3/P-cadherin, as a possible target for immunotherapy of pancreatic, gastric, and colorectal cancers. Clin Cancer Res (2008) 1.17
Adaptive melanin response of the soil fungus Aspergillus niger to UV radiation stress at "Evolution Canyon", Mount Carmel, Israel. PLoS One (2008) 1.17
Independent regulation of hair and skin color by two G protein-coupled pathways. Pigment Cell Melanoma Res (2009) 1.16
Direct chemical evidence for eumelanin pigment from the Jurassic period. Proc Natl Acad Sci U S A (2012) 1.14
Quantitative measures of the effect of the melanocortin 1 receptor on human pigmentary status. J Invest Dermatol (2004) 1.13
The usefulness of 4-amino-3-hydroxyphenylalanine as a specific marker of pheomelanin. Pigment Cell Res (2002) 1.13
The neuromelanin of human substantia nigra: physiological and pathogenic aspects. Pigment Cell Res (2004) 1.12
HLA-A2-restricted CTL epitopes of a novel lung cancer-associated cancer testis antigen, cell division cycle associated 1, can induce tumor-reactive CTL. Int J Cancer (2008) 1.10
Generation and genetic modification of dendritic cells derived from mouse embryonic stem cells. Blood (2002) 1.09
Cutaneous photobiology. The melanocyte vs. the sun: who will win the final round? Pigment Cell Res (2003) 1.07
New melanic pigments in the human brain that accumulate in aging and block environmental toxic metals. Proc Natl Acad Sci U S A (2008) 1.07
Possible role of galectin-9 in cell aggregation and apoptosis of human melanoma cell lines and its clinical significance. Int J Cancer (2002) 1.07
Regulation of eumelanin/pheomelanin synthesis and visible pigmentation in melanocytes by ligands of the melanocortin 1 receptor. Pigment Cell Melanoma Res (2008) 1.07
Giant malignant peripheral nerve sheath tumor of the scalp. J Dermatol (2006) 1.07
Pael receptor induces death of dopaminergic neurons in the substantia nigra via endoplasmic reticulum stress and dopamine toxicity, which is enhanced under condition of parkin inactivation. Hum Mol Genet (2006) 1.06
4-S-Cysteaminylphenol-loaded magnetite cationic liposomes for combination therapy of hyperthermia with chemotherapy against malignant melanoma. Cancer Sci (2007) 1.06
Proliferation potential-related protein, an ideal esophageal cancer antigen for immunotherapy, identified using complementary DNA microarray analysis. Clin Cancer Res (2004) 1.04
Characterization of dendritic cells and macrophages generated by directed differentiation from mouse induced pluripotent stem cells. Stem Cells (2009) 1.04
HLA-A2 and -A24-restricted glypican-3-derived peptide vaccine induces specific CTLs: preclinical study using mice. Int J Oncol (2008) 1.04
Distribution and significance of occult intraepidermal tumor cells surrounding primary melanoma. J Invest Dermatol (2008) 1.03