PubRank

Michael Freissmuth

Author PubWeight™ 83.20‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 The ubiquitin-specific protease Usp4 regulates the cell surface level of the A2A receptor. Mol Pharmacol 2005 2.21
2 Leukemic challenge unmasks a requirement for PI3Kdelta in NK cell-mediated tumor surveillance. Blood 2008 2.04
3 STAT1 acts as a tumor promoter for leukemia development. Cancer Cell 2006 2.00
4 Laryngeal recurrent nerve injury in surgery for benign thyroid diseases: effect of nerve dissection and impact of individual surgeon in more than 27,000 nerves at risk. Ann Surg 2002 1.69
5 Neuromonitoring in thyroid surgery: prospective evaluation of intraoperative electrophysiological responses for the prediction of recurrent laryngeal nerve injury. Ann Surg 2004 1.61
6 The N terminus of monoamine transporters is a lever required for the action of amphetamines. J Biol Chem 2010 1.58
7 Concentrative export from the endoplasmic reticulum of the gamma-aminobutyric acid transporter 1 requires binding to SEC24D. J Biol Chem 2007 1.49
8 Selective serotonin reuptake inhibitors--a new modality for the treatment of lymphoma/leukaemia? Biochem Pharmacol 2007 1.44
9 Amphetamines take two to tango: an oligomer-based counter-transport model of neurotransmitter transport explores the amphetamine action. Mol Pharmacol 2005 1.42
10 Anomalous dopamine release associated with a human dopamine transporter coding variant. J Neurosci 2008 1.41
11 Adenosine receptors: G protein-mediated signalling and the role of accessory proteins. Cell Signal 2002 1.39
12 A kinase-independent function of CDK6 links the cell cycle to tumor angiogenesis. Cancer Cell 2013 1.37
13 The reverse operation of Na(+)/Cl(-)-coupled neurotransmitter transporters--why amphetamines take two to tango. J Neurochem 2009 1.36
14 Identification of an additional interaction domain in transmembrane domains 11 and 12 that supports oligomer formation in the human serotonin transporter. J Biol Chem 2003 1.25
15 Unifying concept of serotonin transporter-associated currents. J Biol Chem 2011 1.24
16 Antibodies directed against Lewis-Y antigen inhibit signaling of Lewis-Y modified ErbB receptors. Cancer Res 2004 1.22
17 The high-affinity binding site for tricyclic antidepressants resides in the outer vestibule of the serotonin transporter. Mol Pharmacol 2010 1.21
18 Ligand-based peptide design and combinatorial peptide libraries to target G protein-coupled receptors. Curr Pharm Des 2010 1.20
19 Two discontinuous segments in the carboxyl terminus are required for membrane targeting of the rat gamma-aminobutyric acid transporter-1 (GAT1). J Biol Chem 2004 1.20
20 The mechanistic basis for noncompetitive ibogaine inhibition of serotonin and dopamine transporters. J Biol Chem 2012 1.19
21 PI3Kδ is essential for tumor clearance mediated by cytotoxic T lymphocytes. PLoS One 2012 1.16
22 Ca(2+)/calmodulin-dependent protein kinase IIα (αCaMKII) controls the activity of the dopamine transporter: implications for Angelman syndrome. J Biol Chem 2012 1.14
23 Mutational analysis of the high-affinity zinc binding site validates a refined human dopamine transporter homology model. PLoS Comput Biol 2013 1.14
24 The conserved glutamate (Glu136) in transmembrane domain 2 of the serotonin transporter is required for the conformational switch in the transport cycle. J Biol Chem 2006 1.13
25 Sec24- and ARFGAP1-dependent trafficking of GABA transporter-1 is a prerequisite for correct axonal targeting. J Neurosci 2008 1.12
26 The role of zinc ions in reverse transport mediated by monoamine transporters. J Biol Chem 2002 1.11
27 The serotonin transporter is an exclusive client of the coat protein complex II (COPII) component SEC24C. J Biol Chem 2011 1.11
28 A quantitative model of amphetamine action on the 5-HT transporter. Br J Pharmacol 2014 1.11
29 JunB inhibits proliferation and transformation in B-lymphoid cells. Blood 2003 1.10
30 Mutations within an intramembrane leucine heptad repeat disrupt oligomer formation of the rat GABA transporter 1. J Biol Chem 2002 1.09
31 Mutations in the carboxyl-terminal SEC24 binding motif of the serotonin transporter impair folding of the transporter. J Biol Chem 2010 1.08
32 Oxytocic plant cyclotides as templates for peptide G protein-coupled receptor ligand design. Proc Natl Acad Sci U S A 2013 1.07
33 The ugly side of amphetamines: short- and long-term toxicity of 3,4-methylenedioxymethamphetamine (MDMA, 'Ecstasy'), methamphetamine and D-amphetamine. Biol Chem 2011 1.03
34 Signal-dependent export of GABA transporter 1 from the ER-Golgi intermediate compartment is specified by a C-terminal motif. J Cell Sci 2008 1.00
35 Oligomer formation by Na+-Cl--coupled neurotransmitter transporters. Eur J Pharmacol 2003 0.99
36 Truncation of the A1 adenosine receptor reveals distinct roles of the membrane-proximal carboxyl terminus in receptor folding and G protein coupling. J Biol Chem 2003 0.99
37 VEGF-induced endothelial cell migration requires urokinase receptor (uPAR)-dependent integrin redistribution. Cardiovasc Res 2012 0.98
38 Electron microscopic visualization of fluorescent signals in cellular compartments and organelles by means of DAB-photoconversion. Histochem Cell Biol 2008 0.98
39 The carboxyl terminus of the Galpha-subunit is the latch for triggered activation of heterotrimeric G proteins. Mol Pharmacol 2005 0.98
40 Heterotrimeric G protein-independent signaling of a G protein-coupled receptor. Direct binding of ARNO/cytohesin-2 to the carboxyl terminus of the A2A adenosine receptor is necessary for sustained activation of the ERK/MAP kinase pathway. J Biol Chem 2005 0.96
41 Removal of the carboxy terminus of the A2A-adenosine receptor blunts constitutive activity: differential effect on cAMP accumulation and MAP kinase stimulation. Naunyn Schmiedebergs Arch Pharmacol 2002 0.96
42 Recruitment of a cytoplasmic chaperone relay by the A2A adenosine receptor. J Biol Chem 2013 0.96
43 Molecular dissection of dual pseudosymmetric solute translocation pathways in human P-glycoprotein. Mol Pharmacol 2010 0.95
44 Switching the clientele: a lysine residing in the C terminus of the serotonin transporter specifies its preference for the coat protein complex II component SEC24C. J Biol Chem 2013 0.95
45 Peptide-based interactions with calnexin target misassembled membrane proteins into endoplasmic reticulum-derived multilamellar bodies. J Mol Biol 2008 0.95
46 TYK2 is a key regulator of the surveillance of B lymphoid tumors. J Clin Invest 2004 0.95
47 The cooperating mutation or "second hit" determines the immunologic visibility toward MYC-induced murine lymphomas. Blood 2011 0.94
48 Probing binding pocket of serotonin transporter by single molecular force spectroscopy on living cells. J Biol Chem 2011 0.94
49 Intra- and postoperative parathyroid hormone-kinetics do not advocate for autotransplantation of discolored parathyroid glands during thyroidectomy. Thyroid 2010 0.94
50 From cradle to twilight: the carboxyl terminus directs the fate of the A(2A)-adenosine receptor. Biochim Biophys Acta 2010 0.94
51 Inhibition of adenylyl cyclase by neuronal P2Y receptors. Br J Pharmacol 2002 0.93
52 Evolution of nerve injury with unexpected EMG signal recovery in thyroid surgery using continuous intraoperative neuromonitoring. World J Surg 2013 0.92
53 MAP kinase stimulation by cAMP does not require RAP1 but SRC family kinases. J Biol Chem 2002 0.92
54 Restricted collision coupling of the A2A receptor revisited: evidence for physical separation of two signaling cascades. J Biol Chem 2008 0.92
55 Pharmacochaperoning of the A1 adenosine receptor is contingent on the endoplasmic reticulum. Mol Pharmacol 2010 0.91
56 Subtype-specific differences in corticotropin-releasing factor receptor complexes detected by fluorescence spectroscopy. Mol Pharmacol 2009 0.91
57 Human anti-macrophage migration inhibitory factor antibodies inhibit growth of human prostate cancer cells in vitro and in vivo. Mol Cancer Ther 2013 0.91
58 Normal parathyroid hormone levels do not exclude permanent hypoparathyroidism after thyroidectomy. Thyroid 2010 0.89
59 Effects of duramycin on cardiac voltage-gated ion channels. Naunyn Schmiedebergs Arch Pharmacol 2008 0.88
60 Signal integration and coincidence detection in the mitogen-activated protein kinase/extracellular signal-regulated kinase (ERK) cascade: concomitant activation of receptor tyrosine kinases and of LRP-1 leads to sustained ERK phosphorylation via down-regulation of dual specificity phosphatases (DUSP1 and -6). J Biol Chem 2011 0.88
61 Oligomerization of the {gamma}-aminobutyric acid transporter-1 is driven by an interplay of polar and hydrophobic interactions in transmembrane helix II. J Biol Chem 2004 0.88
62 Inhibition of xenograft tumor growth and down-regulation of ErbB receptors by an antibody directed against Lewis Y antigen. J Pharmacol Exp Ther 2006 0.87
63 The human D2 dopamine receptor synergizes with the A2A adenosine receptor to stimulate adenylyl cyclase in PC12 cells. Neuropsychopharmacology 2003 0.86
64 Expression of G protein-coupled receptor 19 in human lung cancer cells is triggered by entry into S-phase and supports G(2)-M cell-cycle progression. Mol Cancer Res 2012 0.84
65 Signal interception-based therapies--a double-edged sword in Bcr/abl-induced malignancies? Leuk Lymphoma 2008 0.83
66 Activation and inhibition of G proteins by lipoamines. Mol Pharmacol 2002 0.83
67 ER-bound steps in the biosynthesis of G protein-coupled receptors. Subcell Biochem 2012 0.82
68 A tail of two signals: the C terminus of the A(2A)-adenosine receptor recruits alternative signaling pathways. Mol Pharmacol 2006 0.82
69 Biased inhibition by a suramin analogue of A1-adenosine receptor/G protein coupling in fused receptor/G protein tandems: the A1-adenosine receptor is predominantly coupled to Goalpha in human brain. Naunyn Schmiedebergs Arch Pharmacol 2001 0.82
70 Reengineering the collision coupling and diffusion mode of the A2A-adenosine receptor: palmitoylation in helix 8 relieves confinement. J Biol Chem 2012 0.81
71 A combined approach using transporter-flux assays and mass spectrometry to examine psychostimulant street drugs of unknown content. ACS Chem Neurosci 2012 0.80
72 Commentary on H. Ide et al., "Tyk2 expression and its signaling enhances the invasiveness of prostate cancer cells". Biochem Biophys Res Commun 2007 0.80
73 Perioperative kinetics of parathyroid hormone in unilateral, primary thyroid surgery. Endocrine 2014 0.79
74 Pulmonary pharmacokinetics and safety of nebulized duramycin in healthy male volunteers. Naunyn Schmiedebergs Arch Pharmacol 2008 0.79
75 Development of Gs-selective inhibitory compounds. Methods Enzymol 2002 0.79
76 A two-state model for the diffusion of the A2A adenosine receptor in hippocampal neurons: agonist-induced switch to slow mobility is modified by synapse-associated protein 102 (SAP102). J Biol Chem 2014 0.77
77 Cooperativity between individual transporter protomers: new data fuelling old complexes. J Neurochem 2015 0.76
78 Targeting PI3Kδ: One man's meat is another man's poison. Oncoimmunology 2013 0.75
79 Corrigendum: STAT3 controls IL6-dependent regulation of serotonin transporter function and depression-like behaviour. Sci Rep 2015 0.75
80 Austria should invest in brains, not in bricks, banks or airlines. Nature 2009 0.75
81 Covalent modification of G-proteins by affinity labeling. Methods Mol Biol 2004 0.75
82 Several adaptor proteins promote intracellular localisation of the transporter MRP4/ABCC4 in platelets and haematopoietic cells. Thromb Haemost 2016 0.75
83 Occupancy of the zinc-binding site by transition metals decreases the substrate affinity of the human dopamine transporter by an allosteric mechanism. J Biol Chem 2017 0.75
84 A Kinase-Independent Function of CDK6 Links the Cell Cycle to Tumor Angiogenesis. Cancer Cell 2016 0.75