A further critique of the analytic strategy of adjusting for covariates to identify biologic mediation.

PubWeight™: 3.26‹?› | Rank: Top 1%

🔗 View Article (PMID 15507130)

Published in Epidemiol Perspect Innov on October 08, 2004

Authors

Jay S Kaufman1, Richard F Maclehose, Sol Kaufman

Author Affiliations

1: Department of Epidemiology, University of North Carolina School of Public Health, Chapel Hill, NC 27599-7435 USA. Jay_Kaufman@unc.edu.

Articles citing this

Overadjustment bias and unnecessary adjustment in epidemiologic studies. Epidemiology (2009) 9.00

Odds ratios for mediation analysis for a dichotomous outcome. Am J Epidemiol (2010) 6.03

Bias formulas for sensitivity analysis for direct and indirect effects. Epidemiology (2010) 4.82

Reducing bias through directed acyclic graphs. BMC Med Res Methodol (2008) 3.67

Quantification of collider-stratification bias and the birthweight paradox. Paediatr Perinat Epidemiol (2009) 2.68

Racial disparities in HIV virologic failure: do missed visits matter? J Acquir Immune Defic Syndr (2009) 2.58

Using marginal structural models to estimate the direct effect of adverse childhood social conditions on onset of heart disease, diabetes, and stroke. Epidemiology (2012) 1.80

Policy-relevant proportions for direct effects. Epidemiology (2013) 1.79

Z-scores and the birthweight paradox. Paediatr Perinat Epidemiol (2009) 1.67

Mediation and mechanism. Eur J Epidemiol (2009) 1.64

Association of childhood obesity with atopic and nonatopic asthma: results from the National Health and Nutrition Examination Survey 1999-2006. J Asthma (2010) 1.55

Effect of dietary fiber intake on lipoprotein cholesterol levels independent of estradiol in healthy premenopausal women. Am J Epidemiol (2010) 1.44

Direct and indirect effects for neighborhood-based clustered and longitudinal data. Sociol Methods Res (2010) 1.42

Methodological challenges in causal research on racial and ethnic patterns of cognitive trajectories: measurement, selection, and bias. Neuropsychol Rev (2008) 1.41

Lifecourse social conditions and racial disparities in incidence of first stroke. Ann Epidemiol (2008) 1.33

Conceptual approaches to the study of health disparities. Annu Rev Public Health (2012) 1.33

Sugary soda consumption and albuminuria: results from the National Health and Nutrition Examination Survey, 1999-2004. PLoS One (2008) 1.20

CENP-F expression is associated with poor prognosis and chromosomal instability in patients with primary breast cancer. Int J Cancer (2007) 1.17

Longitudinal impact of physical activity on lipid profiles in middle-aged adults: the Atherosclerosis Risk in Communities Study. J Lipid Res (2009) 1.15

Life-course socioeconomic position and type 2 diabetes mellitus: The Framingham Offspring Study. Am J Epidemiol (2011) 1.13

Redundant causation from a sufficient cause perspective. Epidemiol Perspect Innov (2010) 1.12

A syndemic of psychosocial problems places the MSM (men who have sex with men) population at greater risk of HIV infection. PLoS One (2012) 1.11

The contribution of stress to the social patterning of clinical and subclinical CVD risk factors in African Americans: the Jackson Heart Study. Soc Sci Med (2012) 1.11

Kidney disease and the cumulative burden of life course socioeconomic conditions: the Atherosclerosis Risk in Communities (ARIC) study. Soc Sci Med (2008) 1.10

A sufficient cause based approach to the assessment of mediation. Eur J Epidemiol (2008) 1.08

Subclinical coronary atherosclerosis and neighbourhood deprivation in an urban region. Eur J Epidemiol (2008) 1.03

Role of breastfeeding cessation in mediating the relationship between maternal HIV disease stage and increased child mortality among HIV-exposed uninfected children. Int J Epidemiol (2008) 1.03

Warfarin-related intraventricular hemorrhage: imaging and outcome. Neurology (2011) 1.02

Sensitivity analysis for direct and indirect effects in the presence of exposure-induced mediator-outcome confounders. Epidemiol Biostat Public Health (2014) 1.00

Adult education and child mortality in India: the influence of caste, household wealth, and urbanization. Epidemiology (2008) 1.00

Childhood hardship, maternal smoking, and birth outcomes: a prospective cohort study. Arch Pediatr Adolesc Med (2010) 0.97

Mediation analysis of the relationship between institutional research activity and patient survival. BMC Med Res Methodol (2014) 0.96

Predicting mortality with biomarkers: a population-based prospective cohort study for elderly Costa Ricans. Popul Health Metr (2012) 0.95

Genetic variants, prediagnostic circulating levels of insulin-like growth factors, insulin, and glucose and the risk of colorectal cancer: the Multiethnic Cohort study. Cancer Epidemiol Biomarkers Prev (2012) 0.92

Quantifying mediating effects of endogenous estrogen and insulin in the relation between obesity, alcohol consumption, and breast cancer. Cancer Epidemiol Biomarkers Prev (2012) 0.92

Estimation of the contribution of biomarkers of different metabolic pathways to risk of type 2 diabetes. Eur J Epidemiol (2010) 0.91

Chronic inflammation role in the obesity-diabetes association: a case-cohort study. Diabetol Metab Syndr (2013) 0.91

Season and outdoor temperature in relation to detection and control of hypertension in a large rural Chinese population. Int J Epidemiol (2014) 0.90

The association between blood pressure and years of schooling versus educational credentials: test of the sheepskin effect. Ann Epidemiol (2011) 0.89

Education and obesity at age 40 among American adults. Soc Sci Med (2012) 0.88

Reduced birthweight in short or primiparous mothers: physiological or pathological? BJOG (2010) 0.88

Seasonal modification of the association between temperature and adult emergency department visits for asthma: a case-crossover study. Environ Health (2012) 0.88

Understanding socioeconomic and racial/ethnic status disparities in diet, exercise, and weight: underlying contextual factors and pathways. J Am Diet Assoc (2011) 0.87

Long working hours and metabolic syndrome among Japanese men: a cross-sectional study. BMC Public Health (2012) 0.87

Partitioning the population attributable fraction for a sequential chain of effects. Epidemiol Perspect Innov (2008) 0.85

Parental education as a predictor of offspring behavioural and physiological cardiovascular disease risk factors. Eur J Public Health (2011) 0.83

When is the difference method conservative for assessing mediation? Am J Epidemiol (2015) 0.83

To what extent do biomarkers account for the large social disparities in health in Moscow? Soc Sci Med (2012) 0.81

Total physical activity might not be a good measure in the relationship with HDL cholesterol and triglycerides in a multi-ethnic population: a cross-sectional study. Lipids Health Dis (2011) 0.81

Socioeconomic disparity in survival after breast cancer in ireland: observational study. PLoS One (2014) 0.80

Ethnic variations in mortality in pre-school children in Denmark, 1973-2004. Eur J Epidemiol (2011) 0.79

Is forced migration a barrier to treatment success? Similar HIV treatment outcomes among refugees and a surrounding host community in Kuala Lumpur, Malaysia. AIDS Behav (2014) 0.79

Educational differences in postmenopausal breast cancer--quantifying indirect effects through health behaviors, body mass index and reproductive patterns. PLoS One (2013) 0.79

Lead exposure, B vitamins, and plasma homocysteine in men 55 years of age and older: the VA normative aging study. Environ Health Perspect (2014) 0.79

Clarifying Associations between Childhood Adversity, Social Support, Behavioral Factors, and Mental Health, Health, and Well-Being in Adulthood: A Population-Based Study. Front Psychol (2016) 0.78

Controlled direct and mediated effects: definition, identification and bounds. Scand Stat Theory Appl (2011) 0.78

Role of respondents' education as a mediator and moderator in the association between childhood socio-economic status and later health and wellbeing. BMC Public Health (2014) 0.78

Witnessing a violent death and smoking, alcohol consumption, and marijuana use among adolescents. J Urban Health (2014) 0.78

Participation in vigorous sports, not moderate sports, is positively associated with cardiorespiratory fitness among adolescent girls. J Phys Act Health (2013) 0.77

Social norms and its correlates as a pathway to smoking among young Latino adults. Soc Sci Med (2014) 0.76

Translational Epidemiologic Approaches to Understanding the Consequences of Early-Life Exposures. Behav Genet (2015) 0.75

Comparative Rates of Serious Infections among Patients with Systemic Lupus Erythematosus Receiving Immunosuppressive Medications. Arthritis Rheumatol (2016) 0.75

Differential Recall Bias, Intermediate Confounding, and Mediation Analysis in Life Course Epidemiology: An Analytic Framework with Empirical Example. Front Psychol (2016) 0.75

Birth weight and the risk of atrial fibrillation in whites and African Americans: the Atherosclerosis Risk In Communities (ARIC) study. BMC Cardiovasc Disord (2014) 0.75

Pathways between Socioeconomic Disadvantage and Childhood Growth in the Scottish Longitudinal Study, 1991-2001. PLoS One (2016) 0.75

Mediators of Racial/Ethnic Disparities in Mentored K Award Receipt Among U.S. Medical School Graduates. Acad Med (2017) 0.75

Income inequality within urban settings and depressive symptoms among adolescents. J Epidemiol Community Health (2016) 0.75

Articles cited by this

The moderator-mediator variable distinction in social psychological research: conceptual, strategic, and statistical considerations. J Pers Soc Psychol (1986) 124.55

Identifiability and exchangeability for direct and indirect effects. Epidemiology (1992) 14.88

Socioeconomic factors, health behaviors, and mortality: results from a nationally representative prospective study of US adults. JAMA (1998) 11.90

Fallibility in estimating direct effects. Int J Epidemiol (2002) 8.34

The Lipid Research Clinics Coronary Primary Prevention Trial results. I. Reduction in incidence of coronary heart disease. JAMA (1984) 5.65

Identifiability, exchangeability, and epidemiological confounding. Int J Epidemiol (1986) 4.40

Invariants and noninvariants in the concept of interdependent effects. Scand J Work Environ Health (1988) 2.82

Effect modification and the limits of biological inference from epidemiologic data. J Clin Epidemiol (1991) 2.66

Hostility and increased risk of mortality and acute myocardial infarction: the mediating role of behavioral risk factors. Am J Epidemiol (1997) 1.89

Bounding causal effects under uncontrolled confounding using counterfactuals. Epidemiology (2005) 1.67

Explaining the relation between education and postmenopausal breast cancer. Am J Epidemiol (1997) 1.55

Improved estimation of controlled direct effects in the presence of unmeasured confounding of intermediate variables. Stat Med (2005) 1.51

Epigenesis theory: a mathematical model relating causal concepts of pathogenesis in individuals to disease patterns in populations. Am J Epidemiol (1990) 1.39

Homocysteine and blood pressure in the Third National Health and Nutrition Examination Survey, 1988-1994. Am J Epidemiol (2002) 1.37

Restriction as a method for reducing bias in the estimation of direct effects. Stat Med (1998) 1.36

Causal pathways for CCR5 genotype and HIV progression. J Acquir Immune Defic Syndr (2000) 1.07

Risk factors for a causal intermediate and an endpoint: reconciling differences. Am J Epidemiol (2000) 0.98

Articles by these authors

Blood lipid levels, lipid-lowering medications, and the incidence of atrial fibrillation: the atherosclerosis risk in communities study. Circ Arrhythm Electrophysiol (2012) 1.71

Bounding causal effects under uncontrolled confounding using counterfactuals. Epidemiology (2005) 1.67

Disability and health care costs in the Medicare population. Arch Phys Med Rehabil (2002) 1.57

The influence of depression and anxiety on risk of adult onset vulvodynia. J Womens Health (Larchmt) (2011) 1.54

Carcinoma of the head and neck: a 5- to 20-year experience with preoperative chemotherapy, uncompromised surgery, and selective radiotherapy. Ann Surg Oncol (2003) 1.37

Causal inference from randomized trials in social epidemiology. Soc Sci Med (2003) 1.35

P wave indices, obesity, and the metabolic syndrome: the atherosclerosis risk in communities study. Obesity (Silver Spring) (2011) 1.14

Perceived stereotyping and seeking care for chronic vulvar pain. Pain Med (2013) 0.99

Analytic Bounds on Causal Risk Differences in Directed Acyclic Graphs Involving Three Observed Binary Variables. J Stat Plan Inference (2009) 0.93

Estimating causal effects. Int J Epidemiol (2002) 0.91

Co-morbid pain conditions and feelings of invalidation and isolation among women with vulvodynia. Psychol Health Med (2012) 0.89

The mediation proportion. Epidemiology (2005) 0.88

Assessing the utility of methods for menopausal transition classification in a population-based cohort: the CARDIA Study. Maturitas (2013) 0.79

Physical Activity and Lifetime Risk of Cardiovascular Disease and Cancer. Med Sci Sports Exerc (2017) 0.75