Published in J Pharmacol Toxicol Methods on November 02, 2004
Partial nephrectomy as a model for uremic cardiomyopathy in the mouse. Am J Physiol Renal Physiol (2007) 1.31
Role of diastolic properties in the transition to failure in a mouse model of the cardiac dilatation. Am J Physiol Heart Circ Physiol (2006) 0.94
Regression of pathological cardiac hypertrophy: signaling pathways and therapeutic targets. Pharmacol Ther (2012) 0.88
Rodent models of heart failure: an updated review. Heart Fail Rev (2013) 0.85
Histopathological study of time course changes in inter-renal aortic banding-induced left ventricular hypertrophy of mice. Int J Exp Pathol (2007) 0.83
High-resolution longitudinal MRI of the transition to heart failure. Magn Reson Med (2007) 0.83
Ischemic cardiomyopathy following seizure induction by domoic Acid. Am J Pathol (2011) 0.81
Cardiac Myocyte De Novo DNA Methyltransferases 3a/3b Are Dispensable for Cardiac Function and Remodeling after Chronic Pressure Overload in Mice. PLoS One (2015) 0.77
Relevance of mouse models of cardiac fibrosis and hypertrophy in cardiac research. Mol Cell Biochem (2016) 0.76
Energetics of small hearts. J Physiol (2006) 0.75
Premature ageing in mice expressing defective mitochondrial DNA polymerase. Nature (2004) 11.59
The microbial metabolites, short-chain fatty acids, regulate colonic Treg cell homeostasis. Science (2013) 8.53
Ablation of PGC-1beta results in defective mitochondrial activity, thermogenesis, hepatic function, and cardiac performance. PLoS Biol (2006) 2.86
Improved glucose control and reduced body fat mass in free fatty acid receptor 2-deficient mice fed a high-fat diet. Am J Physiol Endocrinol Metab (2010) 1.90
Remote ischaemic pre- and delayed postconditioning - similar degree of cardioprotection but distinct mechanisms. Exp Physiol (2012) 1.80
Ghrelin increases intake of rewarding food in rodents. Addict Biol (2010) 1.61
Opposing effects of adiponectin receptors 1 and 2 on energy metabolism. Diabetes (2007) 1.59
Acutely reduced locomotor activity is a major contributor to Western diet-induced obesity in mice. Am J Physiol Endocrinol Metab (2007) 1.58
SCFAs induce mouse neutrophil chemotaxis through the GPR43 receptor. PLoS One (2011) 1.28
Arginase inhibition mediates cardioprotection during ischaemia-reperfusion. Cardiovasc Res (2010) 1.27
Adiponectin protects against myocardial ischaemia-reperfusion injury via AMP-activated protein kinase, Akt, and nitric oxide. Cardiovasc Res (2008) 1.24
Pharmacological possibilities for protection against myocardial reperfusion injury. Cardiovasc Res (2002) 1.23
Prolactin and growth hormone regulate adiponectin secretion and receptor expression in adipose tissue. Biochem Biophys Res Commun (2005) 1.20
PPAR-alpha activation protects the type 2 diabetic myocardium against ischemia-reperfusion injury: involvement of the PI3-Kinase/Akt and NO pathway. Am J Physiol Heart Circ Physiol (2009) 1.19
Pharmacodynamic, pharmacokinetic and clinical effects of clevidipine, an ultrashort-acting calcium antagonist for rapid blood pressure control. Cardiovasc Drug Rev (2004) 1.17
Bovine growth hormone transgenic mice are resistant to diet-induced obesity but develop hyperphagia, dyslipidemia, and diabetes on a high-fat diet. Endocrinology (2004) 1.11
Growth hormone receptor deficiency results in blunted ghrelin feeding response, obesity, and hypolipidemia in mice. Am J Physiol Endocrinol Metab (2005) 1.06
Mice lacking melanin-concentrating hormone receptor 1 demonstrate increased heart rate associated with altered autonomic activity. Am J Physiol Regul Integr Comp Physiol (2004) 1.03
Local arginase inhibition during early reperfusion mediates cardioprotection via increased nitric oxide production. PLoS One (2012) 1.01
Phenotypic screening of hepatocyte nuclear factor (HNF) 4-gamma receptor knockout mice. Biochem Biophys Res Commun (2006) 1.00
Mice with experimental colitis show an altered metabolism with decreased metabolic rate. Am J Physiol Gastrointest Liver Physiol (2006) 0.99
Arginase regulates red blood cell nitric oxide synthase and export of cardioprotective nitric oxide bioactivity. Proc Natl Acad Sci U S A (2013) 0.98
Drugs of abuse-induced hyperthermia, blood-brain barrier dysfunction and neurotoxicity: neuroprotective effects of a new antioxidant compound H-290/51. Curr Pharm Des (2007) 0.97
Growth hormone overexpression in the central nervous system results in hyperphagia-induced obesity associated with insulin resistance and dyslipidemia. Diabetes (2005) 0.94
Cardioprotection mediated by rosiglitazone, a peroxisome proliferator-activated receptor gamma ligand, in relation to nitric oxide. Basic Res Cardiol (2006) 0.92
Cell selective cardiovascular biology of microsomal prostaglandin E synthase-1. Circulation (2012) 0.91
Adaptive changes of the Insig1/SREBP1/SCD1 set point help adipose tissue to cope with increased storage demands of obesity. Diabetes (2013) 0.89
Cardioprotective effect induced by brief exposure to nitric oxide before myocardial ischemia-reperfusion in vivo. Nitric Oxide (2002) 0.88
The role of mitochondrial glycerol-3-phosphate acyltransferase-1 in regulating lipid and glucose homeostasis in high-fat diet fed mice. Biochem Biophys Res Commun (2008) 0.88
Arginase inhibition reduces infarct size via nitric oxide, protein kinase C epsilon and mitochondrial ATP-dependent K+ channels. Eur J Pharmacol (2013) 0.88
11-Dehydrocorticosterone causes metabolic syndrome, which is prevented when 11β-HSD1 is knocked out in livers of male mice. Endocrinology (2013) 0.87
GPR10 deficiency in mice results in altered energy expenditure and obesity. Biochem Biophys Res Commun (2007) 0.87
Ageing Fxr deficient mice develop increased energy expenditure, improved glucose control and liver damage resembling NASH. PLoS One (2013) 0.86
Bovine growth hormone-transgenic mice have major alterations in hepatic expression of metabolic genes. Am J Physiol Endocrinol Metab (2003) 0.86
Melanin-concentrating hormone receptor 1 deficiency increases insulin sensitivity in obese leptin-deficient mice without affecting body weight. Diabetes (2006) 0.86
11β-Hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitors still improve metabolic phenotype in male 11β-HSD1 knockout mice suggesting off-target mechanisms. Endocrinology (2013) 0.82
Effects of pharmacological AMP deaminase inhibition and Ampd1 deletion on nucleotide levels and AMPK activation in contracting skeletal muscle. Chem Biol (2014) 0.82
Central NMU signaling in body weight and energy balance regulation: evidence from NMUR2 deletion and chronic central NMU treatment in mice. Am J Physiol Endocrinol Metab (2009) 0.82
G protein-coupled receptor 12 deficiency results in dyslipidemia and obesity in mice. Biochem Biophys Res Commun (2006) 0.81
Myocardial regeneration with stem cells: pharmacological possibilities for efficacy enhancement. Pharmacol Res (2006) 0.81
Time-dependent cardioprotection with calcium antagonism and experimental studies with clevidipine in ischemic-reperfused pig hearts: part II. J Cardiovasc Pharmacol (2002) 0.81
Arginase as a target for treatment of myocardial ischemia-reperfusion injury. Eur J Pharmacol (2013) 0.81
Calcium antagonist clevidipine reduces myocardial reperfusion injury by a mechanism related to bradykinin and nitric oxide. J Cardiovasc Pharmacol (2002) 0.80
Cardioprotective effect of rosuvastatin in vivo is dependent on inhibition of geranylgeranyl pyrophosphate and altered RhoA membrane translocation. Am J Physiol Heart Circ Physiol (2007) 0.80
Growth hormone is necessary for the p53-mediated, obesity-induced insulin resistance in male C57BL/6J x CBA mice. Endocrinology (2013) 0.80
Chronic treatment with nanoparticles exacerbate hyperthermia induced blood-brain barrier breakdown, cognitive dysfunction and brain pathology in the rat. Neuroprotective effects of nanowired-antioxidant compound H-290/51. J Nanosci Nanotechnol (2009) 0.80
Alterations in blood-brain barrier function and brain pathology by morphine in the rat. Neuroprotective effects of antioxidant H-290/51. Acta Neurochir Suppl (2010) 0.78
Endothelin-1 exerts a preconditioning-like cardioprotective effect against ischaemia/reperfusion injury via the ET(A) receptor and the mitochondrial K(ATP) channel in the rat in vivo. Br J Pharmacol (2005) 0.78
Importance of melanin-concentrating hormone receptor for the acute effects of ghrelin. Biochem Biophys Res Commun (2005) 0.78
Endothelial dysfunction in growth hormone transgenic mice. Clin Sci (Lond) (2006) 0.78
Cardiac extrinsic apoptotic pathway is silent in young but activated in elder mice overexpressing bovine GH: interplay with the intrinsic pathway. J Endocrinol (2011) 0.77
Silicon dioxide nanoparticles (SiO2, 40-50 nm) exacerbate pathophysiology of traumatic spinal cord injury and deteriorate functional outcome in the rat. An experimental study using pharmacological and morphological approaches. J Nanosci Nanotechnol (2009) 0.76
Nanoparticles Exacerbate Both Ubiquitin and Heat Shock Protein Expressions in Spinal Cord Injury: Neuroprotective Effects of the Proteasome Inhibitor Carfilzomib and the Antioxidant Compound H-290/51. Mol Neurobiol (2015) 0.76
Local overexpression of GH and GH/IGF1 effects in the adult mouse hippocampus. J Endocrinol (2012) 0.76
Myocardial protection by co-administration of L-arginine and tetrahydrobiopterin during ischemia and reperfusion. Int J Cardiol (2013) 0.76
Adiponectin receptor 2 deficiency results in reduced atherosclerosis in the brachiocephalic artery in apolipoprotein E deficient mice. PLoS One (2013) 0.76
Exacerbation of Methamphetamine Neurotoxicity in Cold and Hot Environments: Neuroprotective Effects of an Antioxidant Compound H-290/51. Mol Neurobiol (2015) 0.76
Metabolic parameters and emotionality are little affected in G-protein coupled receptor 12 (Gpr12) mutant mice. PLoS One (2012) 0.75
Over-expression of Adamts1 in mice alters bone mineral density. J Bone Miner Metab (2011) 0.75
A new antioxidant compound H-290/51 attenuates nanoparticle induced neurotoxicity and enhances neurorepair in hyperthermia. Acta Neurochir Suppl (2010) 0.75
Time-dependent cardioprotection with calcium antagonism and experimental studies with clevidipine in ischemic-reperfused pig hearts: part I. J Cardiovasc Pharmacol (2002) 0.75
The program for phenotyping of genetically modified animals at AstraZeneca. Exp Toxicol Pathol (2006) 0.75