| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
Circulating microRNA-21 as a novel biomarker for hepatocellular carcinoma.
|
J Hepatol
|
2011
|
2.18
|
|
2
|
TIE2-expressing monocytes as a diagnostic marker for hepatocellular carcinoma correlates with angiogenesis.
|
Hepatology
|
2013
|
1.94
|
|
3
|
Critical role of MHC class I-related chain A and B expression on IFN-alpha-stimulated dendritic cells in NK cell activation: impairment in chronic hepatitis C virus infection.
|
J Immunol
|
2003
|
1.67
|
|
4
|
Negative regulation of NK cell activities by inhibitory receptor CD94/NKG2A leads to altered NK cell-induced modulation of dendritic cell functions in chronic hepatitis C virus infection.
|
J Immunol
|
2004
|
1.59
|
|
5
|
A new prognostic system for hepatocellular carcinoma including recurrent cases: a study of 861 patients in a single institution.
|
J Clin Gastroenterol
|
2008
|
1.53
|
|
6
|
Autocrine/paracrine IL-15 that is required for type I IFN-mediated dendritic cell expression of MHC class I-related chain A and B is impaired in hepatitis C virus infection.
|
J Immunol
|
2003
|
1.52
|
|
7
|
The Bcl-xL inhibitor, ABT-737, efficiently induces apoptosis and suppresses growth of hepatoma cells in combination with sorafenib.
|
Hepatology
|
2010
|
1.50
|
|
8
|
Delayed-onset caspase-dependent massive hepatocyte apoptosis upon Fas activation in Bak/Bax-deficient mice.
|
Hepatology
|
2011
|
1.47
|
|
9
|
Expression and role of MICA and MICB in human hepatocellular carcinomas and their regulation by retinoic acid.
|
Int J Cancer
|
2003
|
1.45
|
|
10
|
Hepatitis C virus nonstructural protein 5A modulates the toll-like receptor-MyD88-dependent signaling pathway in macrophage cell lines.
|
J Virol
|
2007
|
1.44
|
|
11
|
Inhibition of autophagy potentiates the antitumor effect of the multikinase inhibitor sorafenib in hepatocellular carcinoma.
|
Int J Cancer
|
2011
|
1.43
|
|
12
|
Increases in p53 expression induce CTGF synthesis by mouse and human hepatocytes and result in liver fibrosis in mice.
|
J Clin Invest
|
2011
|
1.42
|
|
13
|
A novel bulk-culture method for generating mature dendritic cells from mouse bone marrow cells.
|
J Immunol Methods
|
2002
|
1.42
|
|
14
|
Replication-competent recombinant vesicular stomatitis virus encoding hepatitis C virus envelope proteins.
|
J Virol
|
2007
|
1.24
|
|
15
|
Indications and limitations for aged patients with chronic hepatitis C in pegylated interferon alfa-2b plus ribavirin combination therapy.
|
J Hepatol
|
2010
|
1.18
|
|
16
|
Altered interferon-alpha-signaling in natural killer cells from patients with chronic hepatitis C virus infection.
|
J Hepatol
|
2010
|
1.15
|
|
17
|
Mcl-1 and Bcl-xL cooperatively maintain integrity of hepatocytes in developing and adult murine liver.
|
Hepatology
|
2009
|
1.12
|
|
18
|
Alterations in microRNA expression profile in HCV-infected hepatoma cells: involvement of miR-491 in regulation of HCV replication via the PI3 kinase/Akt pathway.
|
Biochem Biophys Res Commun
|
2011
|
1.09
|
|
19
|
BH3-only activator proteins Bid and Bim are dispensable for Bak/Bax-dependent thrombocyte apoptosis induced by Bcl-xL deficiency: molecular requisites for the mitochondrial pathway to apoptosis in platelets.
|
J Biol Chem
|
2011
|
1.08
|
|
20
|
Human blood dendritic cell antigen 3 (BDCA3)(+) dendritic cells are a potent producer of interferon-λ in response to hepatitis C virus.
|
Hepatology
|
2013
|
1.07
|
|
21
|
Lansoprazole for secondary prevention of gastric or duodenal ulcers associated with long-term low-dose aspirin therapy: results of a prospective, multicenter, double-blind, randomized, double-dummy, active-controlled trial.
|
J Gastroenterol
|
2011
|
1.07
|
|
22
|
Serum levels of soluble major histocompatibility complex (MHC) class I-related chain A in patients with chronic liver diseases and changes during transcatheter arterial embolization for hepatocellular carcinoma.
|
Cancer Sci
|
2008
|
1.02
|
|
23
|
Association of enhanced activity of indoleamine 2,3-dioxygenase in dendritic cells with the induction of regulatory T cells in chronic hepatitis C infection.
|
J Gastroenterol
|
2012
|
0.97
|
|
24
|
STAT3 signaling within hepatocytes is required for anemia of inflammation in vivo.
|
J Gastroenterol
|
2009
|
0.97
|
|
25
|
Natural killer cell and hepatic cell interaction via NKG2A leads to dendritic cell-mediated induction of CD4 CD25 T cells with PD-1-dependent regulatory activities.
|
Immunology
|
2006
|
0.96
|
|
26
|
IgG oligosaccharide alterations are a novel diagnostic marker for disease activity and the clinical course of inflammatory bowel disease.
|
Am J Gastroenterol
|
2008
|
0.95
|
|
27
|
Impaired cytokine response in myeloid dendritic cells in chronic hepatitis C virus infection regardless of enhanced expression of Toll-like receptors and retinoic acid inducible gene-I.
|
J Med Virol
|
2008
|
0.94
|
|
28
|
Involvement of p38 signaling pathway in interferon-alpha-mediated antiviral activity toward hepatitis C virus.
|
Biochem Biophys Res Commun
|
2004
|
0.94
|
|
29
|
C16 ceramide accumulates following androgen ablation in LNCaP prostate cancer cells.
|
Prostate
|
2003
|
0.93
|
|
30
|
Concanavalin a injection activates intrahepatic innate immune cells to provoke an antitumor effect in murine liver.
|
Hepatology
|
2004
|
0.92
|
|
31
|
Anticancer chemotherapy inhibits MHC class I-related chain a ectodomain shedding by downregulating ADAM10 expression in hepatocellular carcinoma.
|
Cancer Res
|
2009
|
0.92
|
|
32
|
Long-term effect of lamivudine treatment on the incidence of hepatocellular carcinoma in patients with hepatitis B virus infection.
|
J Gastroenterol
|
2012
|
0.92
|
|
33
|
Pancreatic STAT3 protects mice against caerulein-induced pancreatitis via PAP1 induction.
|
Am J Pathol
|
2012
|
0.91
|
|
34
|
Juvenile hepatocellular carcinoma with congestive liver cirrhosis.
|
J Gastroenterol
|
2005
|
0.91
|
|
35
|
CD1d-mediated stimulation of natural killer T cells selectively activates hepatic natural killer cells to eliminate experimentally disseminated hepatoma cells in murine liver.
|
Int J Cancer
|
2003
|
0.90
|
|
36
|
The efficacy of extended treatment with pegylated interferon plus ribavirin in patients with HCV genotype 1 and slow virologic response in Japan.
|
J Gastroenterol
|
2011
|
0.89
|
|
37
|
Pseudotype hepatitis C virus enters immature myeloid dendritic cells through the interaction with lectin.
|
Virology
|
2004
|
0.88
|
|
38
|
Natural killer cell is a major producer of interferon gamma that is critical for the IL-12-induced anti-tumor effect in mice.
|
Cancer Immunol Immunother
|
2009
|
0.88
|
|
39
|
Lansoprazole for secondary prevention of gastric or duodenal ulcers associated with long-term non-steroidal anti-inflammatory drug (NSAID) therapy: results of a prospective, multicenter, double-blind, randomized, double-dummy, active-controlled trial.
|
J Gastroenterol
|
2012
|
0.88
|
|
40
|
Enhanced ability of peripheral invariant natural killer T cells to produce IL-13 in chronic hepatitis C virus infection.
|
J Hepatol
|
2006
|
0.87
|
|
41
|
Association of vitamin K deficiency with bone metabolism and clinical disease activity in inflammatory bowel disease.
|
Nutrition
|
2011
|
0.87
|
|
42
|
BH3-only protein bid participates in the Bcl-2 network in healthy liver cells.
|
Hepatology
|
2009
|
0.87
|
|
43
|
Liver stiffness measurement by acoustic radiation force impulse is useful in predicting the presence of esophageal varices or high-risk esophageal varices among patients with HCV-related cirrhosis.
|
J Gastroenterol
|
2013
|
0.87
|
|
44
|
Absence of invariant natural killer T cells deteriorates liver inflammation and fibrosis in mice fed high-fat diet.
|
J Gastroenterol
|
2010
|
0.87
|
|
45
|
Bak deficiency inhibits liver carcinogenesis: a causal link between apoptosis and carcinogenesis.
|
J Hepatol
|
2012
|
0.85
|
|
46
|
Effect of interferon alpha-2b plus ribavirin therapy on incidence of hepatocellular carcinoma in patients with chronic hepatitis.
|
Hepatol Res
|
2009
|
0.85
|
|
47
|
Differential alteration of CD56(bright) and CD56 (dim) natural killer cells in frequency, phenotype, and cytokine response in chronic hepatitis C virus infection.
|
J Gastroenterol
|
2011
|
0.85
|
|
48
|
Natural killer cell-mediated ablation of metastatic liver tumors by hydrodynamic injection of IFNalpha gene to mice.
|
Int J Cancer
|
2007
|
0.84
|
|
49
|
Ex vivo induction of IFN-λ3 by a TLR7 agonist determines response to Peg-IFN/ribavirin therapy in chronic hepatitis C patients.
|
J Gastroenterol
|
2013
|
0.84
|
|
50
|
Impaired expression of proteasome subunits and human leukocyte antigens class I in human colon cancer cells.
|
J Gastroenterol Hepatol
|
2003
|
0.84
|
|
51
|
Factors contributing to antiviral effect of adefovir dipivoxil therapy added to ongoing lamivudine treatment in patients with lamivudine-resistant chronic hepatitis B.
|
J Gastroenterol
|
2009
|
0.83
|
|
52
|
Quick generation of fully mature dendritic cells from monocytes with OK432, low-dose prostanoid, and interferon-alpha as potent immune enhancers.
|
J Immunother
|
2005
|
0.83
|
|
53
|
Association of serum IFN-λ3 with inflammatory and fibrosis markers in patients with chronic hepatitis C virus infection.
|
J Gastroenterol
|
2014
|
0.83
|
|
54
|
Upregulation of GRAIL is associated with remission of ulcerative colitis.
|
Am J Physiol Gastrointest Liver Physiol
|
2008
|
0.82
|
|
55
|
Fibroblast growth factor-2 enhances NK sensitivity of hepatocellular carcinoma cells.
|
Int J Cancer
|
2011
|
0.82
|
|
56
|
Altered oligosaccharide structures reduce colitis induction in mice defective in β-1,4-galactosyltransferase.
|
Gastroenterology
|
2012
|
0.81
|
|
57
|
Comprehensive immunological analyses of colorectal cancer patients in the phase I/II study of quickly matured dendritic cell vaccine pulsed with carcinoembryonic antigen peptide.
|
Cancer Immunol Immunother
|
2011
|
0.81
|
|
58
|
Clinical trial of the intratumoral administration of labeled DC combined with systemic chemotherapy for esophageal cancer.
|
J Immunother
|
2012
|
0.81
|
|
59
|
Reduced expression and functional impairment of Toll-like receptor 2 on dendritic cells in chronic hepatitis C virus infection.
|
Hepatol Res
|
2006
|
0.81
|
|
60
|
Significance of liver stiffness measurement by acoustic radiation force impulse (ARFI) among hepatitis C patients.
|
J Med Virol
|
2013
|
0.81
|
|
61
|
Interleukin-1β enhances the production of soluble MICA in human hepatocellular carcinoma.
|
Cancer Immunol Immunother
|
2012
|
0.80
|
|
62
|
Hepatitis C virus-specific CD8+ T cell frequencies are associated with the responses of pegylated interferon-α and ribavirin combination therapy in patients with chronic hepatitis C virus infection.
|
Hepatol Res
|
2010
|
0.79
|
|
63
|
Functional analysis of agalactosyl IgG in inflammatory bowel disease patients.
|
Inflamm Bowel Dis
|
2010
|
0.79
|
|
64
|
EphA2-derived peptide vaccine with amphiphilic poly(gamma-glutamic acid) nanoparticles elicits an anti-tumor effect against mouse liver tumor.
|
Cancer Immunol Immunother
|
2009
|
0.79
|
|
65
|
Involvement of STAT3-regulated hepatic soluble factors in attenuation of stellate cell activity and liver fibrogenesis in mice.
|
Biochem Biophys Res Commun
|
2011
|
0.79
|
|
66
|
Reducing Peg-IFN doses causes later virologic response or no response in HCV genotype 1 patients treated with Peg-IFN alfa-2b plus ribavirin.
|
J Gastroenterol
|
2011
|
0.79
|
|
67
|
Managing hepatitis B virus carriers with systemic chemotherapy or biologic therapy in the outpatient clinic.
|
Hepatol Res
|
2012
|
0.79
|
|
68
|
Deficiency of N-acetylgalactosamine in O-linked oligosaccharides of IgA is a novel biologic marker for Crohn's disease.
|
Inflamm Bowel Dis
|
2012
|
0.78
|
|
69
|
[A patient who developed diaphragmatic hernia 20 months after percutaneous radiofrequency ablation for hepatocellular carcinoma].
|
Nihon Shokakibyo Gakkai Zasshi
|
2010
|
0.78
|
|
70
|
Comparative analyses of regulatory T cell subsets in patients with hepatocellular carcinoma: a crucial role of CD25(-) FOXP3(-) T cells.
|
Int J Cancer
|
2012
|
0.78
|
|
71
|
Involvement of dendritic cell frequency and function in virological relapse in pegylated interferon-alpha and ribavirin therapy for chronic hepatitis C patients.
|
J Med Virol
|
2007
|
0.78
|
|
72
|
Suppressive effect on hepatocyte differentiation of hepatitis C virus core protein.
|
Biochem Biophys Res Commun
|
2006
|
0.77
|
|
73
|
Erratum to: Liver stiffness measurement by acoustic radiation force impulse is useful in predicting the presence of esophageal varices or high-risk esophageal varices among patients with HCV-related cirrhosis.
|
J Gastroenterol
|
2015
|
0.77
|
|
74
|
Type B fulminant hepatitis is closely associated with a highly mutated hepatitis B virus strain.
|
Intervirology
|
2007
|
0.77
|
|
75
|
Efficacy of re-treatment with pegylated interferon plus ribavirin combination therapy for patients with chronic hepatitis C in Japan.
|
J Gastroenterol
|
2011
|
0.77
|
|
76
|
Two types of drug-resistant hepatitis B viral strains emerging alternately and their susceptibility to combination therapy with entecavir and adefovir.
|
Antivir Ther
|
2009
|
0.77
|
|
77
|
Amino acid substitution in the core protein has no impact on relapse in hepatitis C genotype 1 patients treated with peginterferon and ribavirin.
|
J Med Virol
|
2011
|
0.77
|
|
78
|
The combination therapy of α-galactosylceramide and 5-fluorouracil showed antitumor effect synergistically against liver tumor in mice.
|
Int J Cancer
|
2013
|
0.77
|
|
79
|
Early decline of hemoglobin correlates with progression of ribavirin-induced hemolytic anemia during interferon plus ribavirin combination therapy in patients with chronic hepatitis C.
|
J Gastroenterol
|
2006
|
0.77
|
|
80
|
α-Galactosylceramide activates antitumor immunity against liver tumor.
|
Hepatol Res
|
2010
|
0.77
|
|
81
|
Valine, the branched-chain amino acid, suppresses hepatitis C virus RNA replication but promotes infectious particle formation.
|
Biochem Biophys Res Commun
|
2013
|
0.77
|
|
82
|
Suppression of signal transducers and activators of transcription 1 in hepatocellular carcinoma is associated with tumor progression.
|
Int J Cancer
|
2012
|
0.76
|
|
83
|
The Bcl-2 homology domain 3 (BH3)-only proteins Bim and bid are functionally active and restrained by anti-apoptotic Bcl-2 family proteins in healthy liver.
|
J Biol Chem
|
2013
|
0.76
|
|
84
|
Distinct susceptibility of dendritic cell subsets to hepatitis C virus infection: a plausible mechanism of dendritic cell dysfunction.
|
J Gastroenterol
|
2004
|
0.76
|
|
85
|
Efficacy of pegylated interferon plus ribavirin combination therapy for hepatitis C patients with normal ALT levels: a matched case-control study.
|
J Gastroenterol
|
2011
|
0.76
|
|
86
|
Regulation of anergy-related ubiquitin E3 ligase, GRAIL, in murine models of colitis and patients with Crohn's disease.
|
J Gastroenterol
|
2013
|
0.76
|
|
87
|
Using early viral kinetics to predict antiviral outcome in response-guided pegylated interferon plus ribavirin therapy among patients with hepatitis C virus genotype 1.
|
J Gastroenterol
|
2013
|
0.76
|
|
88
|
Interferon-α suppresses hepatitis B virus enhancer II activity via the protein kinase C pathway.
|
Virology
|
2012
|
0.76
|
|
89
|
Should aged patients with chronic hepatitis C be treated with interferon and ribavirin combination therapy?
|
Hepatol Res
|
2006
|
0.75
|
|
90
|
Endoscopic evaluation of low-dose aspirin-induced gastric and duodenal ulcers during prophylaxis with lansoprazole.
|
Hepatogastroenterology
|
2013
|
0.75
|
|
91
|
Lamivudine-to-entecavir switching treatment in type B chronic hepatitis patients without evidence of lamivudine resistance.
|
J Gastroenterol
|
2009
|
0.75
|
|
92
|
The significance of interferon and ribavirin combination therapy followed by interferon monotherapy for patients with chronic hepatitis C in Japan.
|
Hepatol Res
|
2004
|
0.75
|
|
93
|
Molecular pathogenesis of viral hepatitis.
|
Intern Med
|
2003
|
0.75
|
|
94
|
Incidence of hepatocellular carcinoma in HCV-infected patients with normal alanine aminotransferase levels categorized by Japanese treatment guidelines.
|
J Gastroenterol
|
2012
|
0.75
|
|
95
|
[Immunopathogenesis of hepatitis B virus infection].
|
Nihon Rinsho
|
2015
|
0.75
|
|
96
|
[Immuno-pathogenesis of HCV infection].
|
Nihon Rinsho
|
2015
|
0.75
|
|
97
|
[Current status and future prospects of the hepatitis B vaccine].
|
Jpn J Antibiot
|
2016
|
0.75
|
|
98
|
[Vaccine therapies against digestive-system cancers].
|
Nihon Rinsho
|
2011
|
0.75
|
|
99
|
Will there be an HCV meeting in 2020? Summary of the 17th international meeting on hepatitis C virus and related viruses.
|
Gastroenterology
|
2011
|
0.75
|
|
100
|
Initial viral response is the most powerful predictor of the emergence of YMDD mutant virus in chronic hepatitis B patients treated with lamivudine.
|
Hepatol Res
|
2007
|
0.75
|
|
101
|
Early emergence of entecavir-resistant hepatitis B virus in a patient with hepatitis B virus/human immunodeficiency virus coinfection.
|
Hepatol Res
|
2007
|
0.75
|
|
102
|
[Molecular physiopathology of viral hepatitis].
|
Nihon Naika Gakkai Zasshi
|
2002
|
0.75
|