Published in Arthritis Rheum on November 01, 2004
Newborn humans manifest autoantibodies to defined self molecules detected by antigen microarray informatics. J Clin Invest (2007) 2.00
Mechanisms for Hsp70 secretion: crossing membranes without a leader. Methods (2007) 1.42
Mycobacterium tuberculosis heat-shock protein 70 impairs maturation of dendritic cells from bone marrow precursors, induces interleukin-10 production and inhibits T-cell proliferation in vitro. Immunology (2007) 1.19
IL-10 is critically involved in mycobacterial HSP70 induced suppression of proteoglycan-induced arthritis. PLoS One (2009) 1.05
The therapeutic implications of clinically applied modifiers of heat shock protein 70 (Hsp70) expression by tumor cells. Cell Stress Chaperones (2008) 1.04
Heat shock proteins, autoimmunity, and cancer treatment. Autoimmune Dis (2012) 0.98
Heat shock proteins induce T cell regulation of chronic inflammation. Ann Rheum Dis (2006) 0.98
The involvement of heat-shock proteins in the pathogenesis of autoimmune arthritis: a critical appraisal. Semin Arthritis Rheum (2009) 0.91
Tolerization with Hsp65 induces protection against adjuvant-induced arthritis by modulating the antigen-directed interferon-gamma, interleukin-17, and antibody responses. Arthritis Rheum (2009) 0.88
HSP60 as a target of anti-ergotypic regulatory T cells. PLoS One (2008) 0.87
Self heat-shock protein 65-mediated regulation of autoimmune arthritis. J Autoimmun (2009) 0.78
Heat shock protein 60 reactive T cells in juvenile idiopathic arthritis: what is new? Arthritis Res Ther (2009) 0.77
Extracellular cell stress (heat shock) proteins-immune responses and disease: an overview. Philos Trans R Soc Lond B Biol Sci (2018) 0.76
Tolerization against atherosclerosis using heat shock protein 60. Cell Stress Chaperones (2015) 0.76
Modulation of Adjuvant Arthritis by Cellular and Humoral Immunity to Hsp65. Front Immunol (2016) 0.75
Simplicity belies a complex system: a response to the minimal model of immunity of Langman and Cohn. Cell Immunol (2002) 2.90
Toll-like receptors and their ligands control mesenchymal stem cell functions. Blood (2006) 2.67
Antigen microarrays identify unique serum autoantibody signatures in clinical and pathologic subtypes of multiple sclerosis. Proc Natl Acad Sci U S A (2008) 2.57
Heat shock protein 60 enhances CD4+ CD25+ regulatory T cell function via innate TLR2 signaling. J Clin Invest (2006) 2.53
Newborn humans manifest autoantibodies to defined self molecules detected by antigen microarray informatics. J Clin Invest (2007) 2.00
Angiogenesis-inflammation cross-talk: vascular endothelial growth factor is secreted by activated T cells and induces Th1 polarization. J Immunol (2004) 1.71
Functional immunomics: microarray analysis of IgG autoantibody repertoires predicts the future response of mice to induced diabetes. Proc Natl Acad Sci U S A (2004) 1.69
Polyspecificity of T cell and B cell receptor recognition. Semin Immunol (2007) 1.68
T-cell inactivation and immunosuppressive activity induced by HIV gp41 via novel interacting motif. FASEB J (2006) 1.57
T cells respond to heat shock protein 60 via TLR2: activation of adhesion and inhibition of chemokine receptors. FASEB J (2003) 1.56
Emergent dynamics of thymocyte development and lineage determination. PLoS Comput Biol (2006) 1.49
Toward rigorous comprehension of biological complexity: modeling, execution, and visualization of thymic T-cell maturation. Genome Res (2003) 1.48
Heat shock proteins as endogenous adjuvants in sterile and septic inflammation. J Immunol (2005) 1.44
The immune-body cytokine network defines a social architecture of cell interactions. Biol Direct (2006) 1.41
Retracted Evaluation of long-term treatment effect in a type 1 diabetes intervention trial: differences after stimulation with glucagon or a mixed meal. Diabetes Care (2014) 1.38
Heat shock protein 60 activates B cells via the TLR4-MyD88 pathway. J Immunol (2005) 1.35
The HSP60 immune system network. Trends Immunol (2010) 1.33
Four-dimensional realistic modeling of pancreatic organogenesis. Proc Natl Acad Sci U S A (2008) 1.29
Cutting edge: T cells respond to lipopolysaccharide innately via TLR4 signaling. J Immunol (2007) 1.24
Inhibition of adjuvant arthritis by a DNA vaccine encoding human heat shock protein 60. J Immunol (2002) 1.23
Organization of the autoantibody repertoire in healthy newborns and adults revealed by system level informatics of antigen microarray data. Proc Natl Acad Sci U S A (2009) 1.14
Lactobacillus GG bacteria ameliorate arthritis in Lewis rats. J Nutr (2004) 1.13
DNA fragments of the human 60-kDa heat shock protein (HSP60) vaccinate against adjuvant arthritis: identification of a regulatory HSP60 peptide. J Immunol (2003) 1.13
Regulation of experimental autoimmune encephalomyelitis by CD4+, CD25+ and CD8+ T cells: analysis using depleting antibodies. J Autoimmun (2004) 1.12
Heat shock protein 60 inhibits Th1-mediated hepatitis model via innate regulation of Th1/Th2 transcription factors and cytokines. J Immunol (2005) 1.09
An antibody profile of systemic lupus erythematosus detected by antigen microarray. Immunology (2010) 1.08
Cluster analysis of human autoantibody reactivities in health and in type 1 diabetes mellitus: a bio-informatic approach to immune complexity. J Autoimmun (2003) 1.08
Identification of alpha-tropomyosin as a target self-antigen in Behçet's syndrome. Eur J Immunol (2002) 1.05
Ectopic PDX-1 expression in liver ameliorates type 1 diabetes. J Autoimmun (2007) 1.02
Heat shock protein 60 activates cytokine-associated negative regulator suppressor of cytokine signaling 3 in T cells: effects on signaling, chemotaxis, and inflammation. J Immunol (2005) 1.01
Propagation of lewis rat encephalitogenic T cell lines: T-cell-growth-factor is superior to recombinant IL-2. J Neuroimmunol (2002) 1.01
Stress proteins and cytokines are urinary biomarkers for diagnosis and staging of bladder cancer. Eur Urol (2010) 1.00
The natural autoantibody repertoire and autoimmune disease. Biomed Pharmacother (2004) 0.98
HIV-1 fusion peptide targets the TCR and inhibits antigen-specific T cell activation. J Clin Invest (2005) 0.96
DNA vaccination with heat shock protein 60 inhibits cyclophosphamide-accelerated diabetes. J Immunol (2002) 0.96
Therapy with the hsp60 peptide DiaPep277 in C-peptide positive type 1 diabetes patients. Diabetes Metab Res Rev (2007) 0.95
The natural autoantibody repertoire in newborns and adults: a current overview. Adv Exp Med Biol (2012) 0.94
A systems immunology approach to the host-tumor interaction: large-scale patterns of natural autoantibodies distinguish healthy and tumor-bearing mice. PLoS One (2009) 0.94
T cells and autoantibodies to human HSP70 in type 1 diabetes in children. J Autoimmun (2003) 0.92
Induction of IgG3 to LPS via Toll-like receptor 4 co-stimulation. PLoS One (2008) 0.92
HIV-1 gp41 and TCRalpha trans-membrane domains share a motif exploited by the HIV virus to modulate T-cell proliferation. PLoS Pathog (2010) 0.92
NAP, a peptide derived from the activity-dependent neuroprotective protein, modulates macrophage function. Ann N Y Acad Sci (2006) 0.91
Signaling via TLR2 and TLR4 Directly Down-Regulates T Cell Effector Functions: The Regulatory Face of Danger Signals. Front Immunol (2013) 0.90
Complete Freund's adjuvant immunization prolongs survival in experimental prion disease in mice. J Neurosci Res (2003) 0.89
HSP60 as a target of anti-ergotypic regulatory T cells. PLoS One (2008) 0.87
IL-10 mediates resistance to adoptive transfer experimental autoimmune encephalomyelitis in MyD88(-/-) mice. J Immunol (2009) 0.87
Chronic rejection of a lung transplant is characterized by a profile of specific autoantibodies. Immunology (2010) 0.86
D-enantiomer peptide of the TCRalpha transmembrane domain inhibits T-cell activation in vitro and in vivo. FASEB J (2005) 0.86
Peptide p277 of HSP60 signals T cells: inhibition of inflammatory chemotaxis. Int Immunol (2006) 0.86
HSP60 speaks to the immune system in many voices. Novartis Found Symp (2008) 0.86
Characterization of the interacting domain of the HIV-1 fusion peptide with the transmembrane domain of the T-cell receptor. Biochemistry (2008) 0.85
DNA vaccination with CD25 protects rats from adjuvant arthritis and induces an antiergotypic response. J Clin Invest (2004) 0.85
Heparin-disaccharide affects T cells: inhibition of NF-kappaB activation, cell migration, and modulation of intracellular signaling. J Leukoc Biol (2004) 0.85
Retracted Treatment of recent-onset type 1 diabetic patients with DiaPep277: results of a double-blind, placebo-controlled, randomized phase 3 trial. Diabetes Care (2014) 0.85
A structurally altered D,L-amino acid TCRalpha transmembrane peptide interacts with the TCRalpha and inhibits T-cell activation in vitro and in an animal model. Biochemistry (2007) 0.85
Proteins and their derived peptides as carriers in a conjugate vaccine for Streptococcus pneumoniae: self-heat shock protein 60 and tetanus toxoid. J Immunol (2003) 0.84
Heat shock protein 60, via MyD88 innate signaling, protects B cells from apoptosis, spontaneous and induced. J Immunol (2009) 0.84
Network theory analysis of antibody-antigen reactivity data: the immune trees at birth and adulthood. PLoS One (2011) 0.84
Identification of aldolase as a target antigen in Alzheimer's disease. J Immunol (2005) 0.83
Proliferation and competition in discrete biological systems. Bull Math Biol (2003) 0.83
Analyses of antigen dependency networks unveil immune system reorganization between birth and adulthood. Chaos (2011) 0.83
G-CSF enhances the adhesion of encephalitogenic T cells to extracellular matrix components: a possible mechanism for exacerbation of multiple sclerosis. J Neuroimmunol (2006) 0.83
Monoclonal antibody to a DNA-binding domain of p53 mimics charge structure of DNA: anti-idiotypes to the anti-p53 antibody are anti-DNA. Eur J Immunol (2004) 0.82
Autoimmune encephalomyelitis and uveitis induced by T cell immunity to self beta-synuclein. J Immunol (2003) 0.82
Self HSP60 peptide serves as an immunogenic carrier for a CTL epitope against persistence of murine cytomegalovirus in the salivary gland. Vaccine (2005) 0.82
Split immunity: immune inhibition of rat gliomas by subcutaneous exposure to unmodified live tumor cells. J Immunol (2011) 0.82
Do all creatures possess an acquired immune system of some sort? Bioessays (2014) 0.81
Reactive animation: from piecemeal experimentation to reactive biological systems. Autoimmunity (2011) 0.81
T cell vaccination benefits relapsing progressive multiple sclerosis patients: a randomized, double-blind clinical trial. PLoS One (2012) 0.80
Integrative analysis correlates donor transcripts to recipient autoantibodies in primary graft dysfunction after lung transplantation. Immunology (2010) 0.80
Epstein-Barr virus antibodies mark systemic lupus erythematosus and scleroderma patients negative for anti-DNA. Immunology (2014) 0.80
The heuristics of biologic theory: the case of self-nonself discrimination. Cell Immunol (2003) 0.80
DNA vaccines coding for heat-shock proteins (HSPs): tools for the activation of HSP-specific regulatory T cells. Expert Opin Biol Ther (2005) 0.79
Regulatory T cells in autoimmune diseases: anti-ergotypic T cells. Int Rev Immunol (2005) 0.79
A conjugate vaccine composed of a heat shock protein 60 T-cell epitope peptide (p458) and Neisseria meningitidis type B capsular polysaccharide. Vaccine (2006) 0.78
Individual and meta-immune networks. Phys Biol (2013) 0.78
Beta-lactam antibiotics modulate T-cell functions and gene expression via covalent binding to cellular albumin. Proc Natl Acad Sci U S A (2013) 0.78
Chimeric vaccine composed of viral peptide and mammalian heat-shock protein 60 peptide protects against West Nile virus challenge. Immunology (2010) 0.78
Amyloid beta-HSP60 peptide conjugate vaccine treats a mouse model of Alzheimer's disease. Vaccine (2011) 0.78
Knock-out of the histidine decarboxylase gene modifies the repertoire of natural autoantibodies. J Autoimmun (2004) 0.78
T cell vaccination induces the elimination of EAE effector T cells: analysis using GFP-transduced, encephalitogenic T cells. J Autoimmun (2010) 0.78
Prevalence of autoantibodies to the p53 protein in autoimmune hepatitis. Autoimmunity (2002) 0.78
Anti-ergotypic T cells in naïve rats. J Autoimmun (2005) 0.78
Unique gene expression patterns in human T-cell lines generated from multiple sclerosis patients by stimulation with a synthetic MOG peptide. Clin Dev Immunol (2005) 0.77