Published in Environ Health Perspect on November 01, 2004
Xenoestrogens at picomolar to nanomolar concentrations trigger membrane estrogen receptor-alpha-mediated Ca2+ fluxes and prolactin release in GH3/B6 pituitary tumor cells. Environ Health Perspect (2005) 2.53
EDC-2: The Endocrine Society's Second Scientific Statement on Endocrine-Disrupting Chemicals. Endocr Rev (2015) 2.51
Designing Endocrine Disruption Out of the Next Generation of Chemicals. Green Chem (2013) 2.47
Bisphenol S disrupts estradiol-induced nongenomic signaling in a rat pituitary cell line: effects on cell functions. Environ Health Perspect (2013) 1.89
A round robin approach to the analysis of bisphenol A (BPA) in human blood samples. Environ Health (2014) 1.88
Low doses of bisphenol A and diethylstilbestrol impair Ca2+ signals in pancreatic alpha-cells through a nonclassical membrane estrogen receptor within intact islets of Langerhans. Environ Health Perspect (2005) 1.79
Combinations of physiologic estrogens with xenoestrogens alter ERK phosphorylation profiles in rat pituitary cells. Environ Health Perspect (2010) 1.52
Low doses of bisphenol A promote human seminoma cell proliferation by activating PKA and PKG via a membrane G-protein-coupled estrogen receptor. Environ Health Perspect (2009) 1.47
Endocrine-disrupting chemicals: associated disorders and mechanisms of action. J Environ Public Health (2012) 1.40
Maternal bisphenol a exposure promotes the development of experimental asthma in mouse pups. Environ Health Perspect (2010) 1.35
Xenoestrogens are potent activators of nongenomic estrogenic responses. Steroids (2006) 1.31
Environmental estrogens induce mast cell degranulation and enhance IgE-mediated release of allergic mediators. Environ Health Perspect (2007) 1.20
Nongenomic actions of low concentration estrogens and xenoestrogens on multiple tissues. Mol Cell Endocrinol (2007) 1.14
Retracted G-protein-coupled receptor 30 and estrogen receptor-alpha are involved in the proliferative effects induced by atrazine in ovarian cancer cells. Environ Health Perspect (2008) 1.13
Nongenomic signaling pathways of estrogen toxicity. Toxicol Sci (2009) 1.13
Effect of endocrine disruptor pesticides: a review. Int J Environ Res Public Health (2011) 1.10
Alkylphenol xenoestrogens with varying carbon chain lengths differentially and potently activate signaling and functional responses in GH3/B6/F10 somatomammotropes. Environ Health Perspect (2008) 1.04
Nongenomic actions of estradiol compared with estrone and estriol in pituitary tumor cell signaling and proliferation. FASEB J (2008) 1.04
Effects of atrazine on estrogen receptor α- and G protein-coupled receptor 30-mediated signaling and proliferation in cancer cells and cancer-associated fibroblasts. Environ Health Perspect (2015) 1.00
Membrane estrogen receptor-alpha-mediated nongenomic actions of phytoestrogens in GH3/B6/F10 pituitary tumor cells. J Mol Signal (2009) 0.98
Mitogen-activated protein kinase (MAPK) pathway mediates the oestrogen-like activities of ginsenoside Rg1 in human breast cancer (MCF-7) cells. Br J Pharmacol (2009) 0.96
Low concentrations of bisphenol A induce mouse spermatogonial cell proliferation by G protein-coupled receptor 30 and estrogen receptor-α. Environ Health Perspect (2011) 0.94
Proliferative and anti-proliferative effects of dietary levels of phytoestrogens in rat pituitary GH3/B6/F10 cells - the involvement of rapidly activated kinases and caspases. BMC Cancer (2009) 0.94
Differential regulation of dopamine transporter function and location by low concentrations of environmental estrogens and 17beta-estradiol. Environ Health Perspect (2009) 0.92
Mixtures of xenoestrogens disrupt estradiol-induced non-genomic signaling and downstream functions in pituitary cells. Environ Health (2013) 0.92
A low concentration of genistein induces estrogen receptor-alpha and insulin-like growth factor-I receptor interactions and proliferation in uterine leiomyoma cells. Hum Reprod (2008) 0.91
Estrogen- and xenoestrogen-induced ERK signaling in pituitary tumor cells involves estrogen receptor-α interactions with G protein-αi and caveolin I. Steroids (2011) 0.90
Sex steroids and potential mechanisms of non-genomic endocrine disruption in invertebrates. Ecotoxicology (2007) 0.89
Combinations of physiologic estrogens with xenoestrogens alter calcium and kinase responses, prolactin release, and membrane estrogen receptor trafficking in rat pituitary cells. Environ Health (2010) 0.88
Nongenomic mechanisms of physiological estrogen-mediated dopamine efflux. BMC Neurosci (2009) 0.88
Disentangling the molecular mechanisms of action of endogenous and environmental estrogens. Pflugers Arch (2004) 0.87
Coexposure to phytoestrogens and bisphenol a mimics estrogenic effects in an additive manner. Toxicol Sci (2013) 0.84
Estrogens of multiple classes and their role in mental health disease mechanisms. Int J Womens Health (2010) 0.84
Quantitative changes in intracellular calcium and extracellular-regulated kinase activation measured in parallel in CHO cells stably expressing serotonin (5-HT) 5-HT2A or 5-HT2C receptors. BMC Neurosci (2012) 0.83
Molecular mechanism(s) of endocrine-disrupting chemicals and their potent oestrogenicity in diverse cells and tissues that express oestrogen receptors. J Cell Mol Med (2012) 0.83
Rapid actions of xenoestrogens disrupt normal estrogenic signaling. Steroids (2013) 0.82
Non-genomic effects of xenoestrogen mixtures. Int J Environ Res Public Health (2012) 0.81
Endosulfan upregulates AP-1 binding and ARE-mediated transcription via ERK1/2 and p38 activation in HepG2 cells. Toxicology (2011) 0.80
Disruptive environmental chemicals and cellular mechanisms that confer resistance to cell death. Carcinogenesis (2015) 0.77
Roles of ERβ and GPR30 in Proliferative Response of Human Bladder Cancer Cell to Estrogen. Biomed Res Int (2015) 0.76
Endocrine-disrupting chemicals and uterine fibroids. Fertil Steril (2016) 0.75
BPA Directly Decreases GnRH Neuronal Activity via Noncanonical Pathway. Endocrinology (2016) 0.75
Molecular basis of agonism and antagonism in the oestrogen receptor. Nature (1997) 9.09
Bisphenol-A: an estrogenic substance is released from polycarbonate flasks during autoclaving. Endocrinology (1993) 6.20
Recycling the cell cycle: cyclins revisited. Cell (2004) 6.04
Estrogen-induced activation of Erk-1 and Erk-2 requires the G protein-coupled receptor homolog, GPR30, and occurs via trans-activation of the epidermal growth factor receptor through release of HB-EGF. Mol Endocrinol (2000) 5.53
The pesticides endosulfan, toxaphene, and dieldrin have estrogenic effects on human estrogen-sensitive cells. Environ Health Perspect (1994) 3.12
Functional toxicology: a new approach to detect biologically active xenobiotics. Environ Health Perspect (1993) 3.03
Estrogen receptor alpha mediates the nongenomic activation of endothelial nitric oxide synthase by estrogen. J Clin Invest (1999) 2.71
Estrogen action via the cAMP signaling pathway: stimulation of adenylate cyclase and cAMP-regulated gene transcription. Proc Natl Acad Sci U S A (1994) 2.41
New insights into the control of MAP kinase pathways. Exp Cell Res (1999) 2.39
Proximal events in signaling by plasma membrane estrogen receptors. J Biol Chem (2002) 2.31
Combining xenoestrogens at levels below individual no-observed-effect concentrations dramatically enhances steroid hormone action. Environ Health Perspect (2002) 2.26
ERs associate with and regulate the production of caveolin: implications for signaling and cellular actions. Mol Endocrinol (2002) 2.20
Src kinase mediates phosphatidylinositol 3-kinase/Akt-dependent rapid endothelial nitric-oxide synthase activation by estrogen. J Biol Chem (2002) 1.91
Nongenomic actions of estrogens and xenoestrogens by binding at a plasma membrane receptor unrelated to estrogen receptor alpha and estrogen receptor beta. Proc Natl Acad Sci U S A (2000) 1.86
Estrogen receptor alpha and endothelial nitric oxide synthase are organized into a functional signaling module in caveolae. Circ Res (2000) 1.86
Effect of highly bioaccumulated polychlorinated biphenyl congeners on estrogen and androgen receptor activity. Toxicology (2001) 1.84
Rapid insulinotropic effect of 17beta-estradiol via a plasma membrane receptor. FASEB J (1998) 1.54
Estrogen receptor-alpha detected on the plasma membrane of aldehyde-fixed GH3/B6/F10 rat pituitary tumor cells by enzyme-linked immunocytochemistry. Endocrinology (1999) 1.53
Retracted Cholesterol depletion inhibits epidermal growth factor receptor transactivation by angiotensin II in vascular smooth muscle cells: role of cholesterol-rich microdomains and focal adhesions in angiotensin II signaling. J Biol Chem (2001) 1.53
Comparison of an array of in vitro assays for the assessment of the estrogenic potential of natural and synthetic estrogens, phytoestrogens and xenoestrogens. Toxicology (2001) 1.37
Quantitative measurement of estrogen-induced ERK 1 and 2 activation via multiple membrane-initiated signaling pathways. Steroids (2004) 1.31
Rapid actions of estrogens in GH3/B6 pituitary tumor cells via a plasma membrane version of estrogen receptor-alpha. Steroids (1999) 1.31
Development of a marker of estrogenic exposure in human serum. Clin Chem (1995) 1.26
Membrane oestrogen receptors on rat pituitary tumour cells: immuno-identification and responses to oestradiol and xenoestrogens. Exp Physiol (1999) 1.22
Integration of signals from receptor tyrosine kinases and g protein-coupled receptors. Neurosignals (2002) 1.22
Rapid effects of estrogen to modulate G protein-coupled receptors via activation of protein kinase A and protein kinase C pathways. Steroids (1999) 1.20
Cellular Functions of the Plasma Membrane Estrogen Receptor. Trends Endocrinol Metab (1999) 1.18
Prediction of ligand binding affinity and orientation of xenoestrogens to the estrogen receptor by molecular dynamics simulations and the linear interaction energy method. J Med Chem (2004) 1.10
The other estrogen receptor in the plasma membrane: implications for the actions of environmental estrogens. Environ Health Perspect (1995) 1.09
Strain differences in vaginal responses to the xenoestrogen bisphenol A. Environ Health Perspect (2000) 1.08
Environmental estrogenic pollutants induce acute vascular relaxation by inhibiting L-type Ca2+ channels in smooth muscle cells. FASEB J (1998) 1.08
Diversity of G protein-coupled receptor signaling pathways to ERK/MAP kinase. Neurosignals (2002) 1.07
A comparison of membrane vs. intracellular estrogen receptor-alpha in GH(3)/B6 pituitary tumor cells using a quantitative plate immunoassay. Steroids (2001) 1.04
Estradiol coupling to endothelial nitric oxide stimulates gonadotropin-releasing hormone release from rat median eminence via a membrane receptor. Endocrinology (1999) 1.02
Estrogens inhibit l-glutamate uptake activity of astrocytes via membrane estrogen receptor alpha. J Neurochem (2003) 0.98
Endocrine disruptors: can biological effects and environmental risks be predicted? Regul Toxicol Pharmacol (2002) 0.98
Estrogenic effects of organochlorine pesticides on uterine leiomyoma cells in vitro. Toxicol Sci (2000) 0.97
A Galphas protein-coupled membrane receptor, distinct from the classical oestrogen receptor, transduces rapid effects of oestradiol on [Ca2+]i in female rat distal colon. Mol Cell Endocrinol (2003) 0.95
17beta-Estradiol and environmental estrogens significantly affect mammalian sperm function. Hum Reprod (2003) 0.95
Oscillations in activities of enzymes in pancreatic islet subcellular fractions induced by physiological concentrations of effectors. Diabetes (1997) 0.95
Cellular and biochemical mechanisms by which environmental oestrogens influence reproductive function. Hum Reprod Update (2000) 0.92
Significant effects of mild endogenous hormonal changes in humans: considerations for low-dose testing. Environ Health Perspect (2001) 0.90
Xenoestrogens and the induction of proliferative effects in breast cancer cells via direct activation of oestrogen receptor alpha. Food Addit Contam (2004) 0.89
Stimulation of alkaline phosphatase activity in Ishikawa cells induced by various phytoestrogens and synthetic estrogens. J Steroid Biochem Mol Biol (2002) 0.87
The phosphatidylinositol 3-kinase inhibitor LY294002 binds the estrogen receptor and inhibits 17beta-estradiol-induced transcriptional activity of an estrogen sensitive reporter gene. Mol Cell Endocrinol (2003) 0.85
Benzo[a]pyrene regulates osteoblast proliferation through an estrogen receptor-related cyclooxygenase-2 pathway. Chem Res Toxicol (2004) 0.85
An assay for the detection of xenoestrogens based on a promoter containing overlapping EREs. Environ Health Perspect (1999) 0.83
Modulation of prolactin expression by xenoestrogens. Gen Comp Endocrinol (2002) 0.83
Phytoestrogens have agonistic and combinatorial effects on estrogen-responsive gene expression in MCF-7 human breast cancer cells. Endocrine (1998) 0.83
Detecting endocrine-disrupting compounds by fast impedance measurements. Environ Sci Technol (2002) 0.82
The human acrosome reaction is highly sensitive to inhibition by cyclodiene insecticides. J Androl (1998) 0.82
Assessment of the effects of metabolism on the estrogenic activity of xenoestrogens: a two-stage approach coupling human liver microsomes and a yeast estrogenicity assay. J Pharmacol Exp Ther (2001) 0.81
Selective modulation of ER-beta by estradiol and xenoestrogens in human breast cancer cell lines. Cell Mol Life Sci (2003) 0.80
A reporter gene assay for evaluation of tissue-specific responses to estrogens based on the differential use of promoters A to F of the human estrogen receptor alpha gene. J Pharmacol Toxicol Methods (2003) 0.79
Combined effect of xenoestrogens and growth factors in two estrogen-responsive cell lines. Endocrine (2002) 0.79
Classification of environmental estrogens by physicochemical properties using principal component analysis and hierarchical cluster analysis. J Chem Inf Comput Sci (2001) 0.78
Influence of the structural diversity of data sets on the statistical quality of three-dimensional quantitative structure-activity relationship (3D-QSAR) models: predicting the estrogenic activity of xenoestrogens. Chem Res Toxicol (2002) 0.78
Chapel Hill bisphenol A expert panel consensus statement: integration of mechanisms, effects in animals and potential to impact human health at current levels of exposure. Reprod Toxicol (2007) 4.04
In vitro molecular mechanisms of bisphenol A action. Reprod Toxicol (2007) 3.69
Why public health agencies cannot depend on good laboratory practices as a criterion for selecting data: the case of bisphenol A. Environ Health Perspect (2008) 3.27
Xenoestrogens at picomolar to nanomolar concentrations trigger membrane estrogen receptor-alpha-mediated Ca2+ fluxes and prolactin release in GH3/B6 pituitary tumor cells. Environ Health Perspect (2005) 2.53
Bisphenol S disrupts estradiol-induced nongenomic signaling in a rat pituitary cell line: effects on cell functions. Environ Health Perspect (2013) 1.89
Combinations of physiologic estrogens with xenoestrogens alter ERK phosphorylation profiles in rat pituitary cells. Environ Health Perspect (2010) 1.52
Estradiol activates mast cells via a non-genomic estrogen receptor-alpha and calcium influx. Mol Immunol (2006) 1.51
Maternal bisphenol a exposure promotes the development of experimental asthma in mouse pups. Environ Health Perspect (2010) 1.35
Quantitative measurement of estrogen-induced ERK 1 and 2 activation via multiple membrane-initiated signaling pathways. Steroids (2004) 1.31
Mechanisms of membrane estrogen receptor-alpha-mediated rapid stimulation of Ca2+ levels and prolactin release in a pituitary cell line. Am J Physiol Endocrinol Metab (2004) 1.30
Membrane estrogen receptor-alpha levels predict estrogen-induced ERK1/2 activation in MCF-7 cells. Breast Cancer Res (2004) 1.26
Environmental estrogens induce mast cell degranulation and enhance IgE-mediated release of allergic mediators. Environ Health Perspect (2007) 1.20
Membrane estrogen receptor-alpha levels in MCF-7 breast cancer cells predict cAMP and proliferation responses. Breast Cancer Res (2004) 1.20
The roles of membrane estrogen receptor subtypes in modulating dopamine transporters in PC-12 cells. J Neurochem (2008) 1.13
Synergism between a serotonin 5-HT2A receptor (5-HT2AR) antagonist and 5-HT2CR agonist suggests new pharmacotherapeutics for cocaine addiction. ACS Chem Neurosci (2012) 1.06
Alkylphenol xenoestrogens with varying carbon chain lengths differentially and potently activate signaling and functional responses in GH3/B6/F10 somatomammotropes. Environ Health Perspect (2008) 1.04
Flawed experimental design reveals the need for guidelines requiring appropriate positive controls in endocrine disruption research. Toxicol Sci (2010) 0.99
Membrane estrogen receptor-alpha-mediated nongenomic actions of phytoestrogens in GH3/B6/F10 pituitary tumor cells. J Mol Signal (2009) 0.98
Serotonin 5-HT2C receptor protein expression is enriched in synaptosomal and post-synaptic compartments of rat cortex. J Neurochem (2010) 0.98
Regulation of the membrane estrogen receptor-alpha: role of cell density, serum, cell passage number, and estradiol. FASEB J (2002) 0.94
Proliferative and anti-proliferative effects of dietary levels of phytoestrogens in rat pituitary GH3/B6/F10 cells - the involvement of rapidly activated kinases and caspases. BMC Cancer (2009) 0.94
Synthesis and evaluation of dimeric derivatives of 5-HT(2A) receptor (5-HT(2A)R) antagonist M-100907. ACS Chem Neurosci (2011) 0.92
Differential regulation of dopamine transporter function and location by low concentrations of environmental estrogens and 17beta-estradiol. Environ Health Perspect (2009) 0.92
Mixtures of xenoestrogens disrupt estradiol-induced non-genomic signaling and downstream functions in pituitary cells. Environ Health (2013) 0.92
Intracellular signaling involved in estrogen regulation of serotonin reuptake. Mol Cell Endocrinol (2004) 0.90
Nongenomic mechanisms of physiological estrogen-mediated dopamine efflux. BMC Neurosci (2009) 0.88
Combinations of physiologic estrogens with xenoestrogens alter calcium and kinase responses, prolactin release, and membrane estrogen receptor trafficking in rat pituitary cells. Environ Health (2010) 0.88
Correlation of membrane glucocorticoid receptor levels with glucocorticoid-induced apoptotic competence using mutant leukemic and lymphoma cells lines. J Cell Biochem (2002) 0.86
Quantitative changes in intracellular calcium and extracellular-regulated kinase activation measured in parallel in CHO cells stably expressing serotonin (5-HT) 5-HT2A or 5-HT2C receptors. BMC Neurosci (2012) 0.83
Non-genomic effects of xenoestrogen mixtures. Int J Environ Res Public Health (2012) 0.81
Subchronic exposure to phytoestrogens alone and in combination with diethylstilbestrol - pituitary tumor induction in Fischer 344 rats. Nutr Metab (Lond) (2010) 0.81
Peptide inhibitors disrupt the serotonin 5-HT2C receptor interaction with phosphatase and tensin homolog to allosterically modulate cellular signaling and behavior. J Neurosci (2013) 0.81
Cell cycle regulation, neurogenesis, and depression. Proc Natl Acad Sci U S A (2008) 0.77
Direct estradiol and diethylstilbestrol actions on early- versus late-stage prostate cancer cells. Prostate (2014) 0.75