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1
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Simvastatin impairs exercise training adaptations.
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J Am Coll Cardiol
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2013
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2.41
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2
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Mitochondrial dysfunction precedes insulin resistance and hepatic steatosis and contributes to the natural history of non-alcoholic fatty liver disease in an obese rodent model.
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J Hepatol
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2010
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2.09
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3
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Increased muscle sympathetic nerve activity acutely alters conduit artery shear rate patterns.
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Am J Physiol Heart Circ Physiol
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2010
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2.06
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4
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Aging induces muscle-specific impairment of endothelium-dependent dilation in skeletal muscle feed arteries.
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J Appl Physiol (1985)
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2002
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1.61
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5
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Endothelial function and exercise training: evidence from studies using animal models.
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Med Sci Sports Exerc
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2006
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1.59
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6
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Influence of exercise and perivascular adipose tissue on coronary artery vasomotor function in a familial hypercholesterolemic porcine atherosclerosis model.
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J Appl Physiol (1985)
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2009
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1.53
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7
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Time course of changes in collateral blood flow and isolated vessel size and gene expression after femoral artery occlusion in rats.
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Am J Physiol Heart Circ Physiol
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2004
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1.50
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8
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Quantitative analysis of exercise-induced enhancement of early- and late-systolic retrograde coronary blood flow.
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J Appl Physiol (1985)
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2009
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1.49
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9
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Daily exercise vs. caloric restriction for prevention of nonalcoholic fatty liver disease in the OLETF rat model.
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Am J Physiol Gastrointest Liver Physiol
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2011
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1.41
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10
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Gene targeting with zinc finger nucleases to produce cloned eGFP knockout pigs.
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Mol Reprod Dev
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2011
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1.36
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11
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Impact of shear rate modulation on vascular function in humans.
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Hypertension
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2009
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1.31
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12
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Exercise training regulates SOD-1 and oxidative stress in porcine aortic endothelium.
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Am J Physiol Heart Circ Physiol
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2002
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1.30
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13
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Arterial endothelial function in a porcine model of early stage atherosclerotic vascular disease.
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Int J Exp Pathol
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2005
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1.30
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14
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Exercise preserves endothelium-dependent relaxation in coronary arteries of hypercholesterolemic male pigs.
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J Appl Physiol (1985)
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2003
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1.28
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15
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Exercise training reverses age-related decrements in endothelium-dependent dilation in skeletal muscle feed arteries.
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J Appl Physiol (1985)
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2009
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1.25
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16
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Vascular effects of exercise: endothelial adaptations beyond active muscle beds.
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Physiology (Bethesda)
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2011
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1.24
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17
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Exercise and diet induced weight loss improves measures of oxidative stress and insulin sensitivity in adults with characteristics of the metabolic syndrome.
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Am J Physiol Endocrinol Metab
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2007
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1.23
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18
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Increased brachial artery retrograde shear rate at exercise onset is abolished during prolonged cycling: role of thermoregulatory vasodilation.
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J Appl Physiol (1985)
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2010
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1.23
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19
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Selected Contribution: Aging impairs nitric oxide and prostacyclin mediation of endothelium-dependent dilation in soleus feed arteries.
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J Appl Physiol (1985)
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2003
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1.19
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20
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Elevated skeletal muscle irisin precursor FNDC5 mRNA in obese OLETF rats.
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Metabolism
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2013
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1.19
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21
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Shear stress induces eNOS mRNA expression and improves endothelium-dependent dilation in senescent soleus muscle feed arteries.
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J Appl Physiol (1985)
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2004
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1.17
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22
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Changes in skeletal muscle mitochondria in response to the development of type 2 diabetes or prevention by daily wheel running in hyperphagic OLETF rats.
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Am J Physiol Endocrinol Metab
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2010
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1.15
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23
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Changes in visceral adipose tissue mitochondrial content with type 2 diabetes and daily voluntary wheel running in OLETF rats.
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J Physiol
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2009
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1.15
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24
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Brachial artery vasodilatation during prolonged lower limb exercise: role of shear rate.
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Exp Physiol
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2011
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1.13
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25
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Disturbed blood flow acutely induces activation and apoptosis of the human vascular endothelium.
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Hypertension
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2013
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1.13
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26
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Physical activity and atherosclerosis: which animal model?
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Can J Appl Physiol
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2004
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1.09
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27
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Effects of endurance exercise training, metformin, and their combination on adipose tissue leptin and IL-10 secretion in OLETF rats.
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J Appl Physiol (1985)
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2012
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1.08
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28
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Divergent phenotype of rat thoracic and abdominal perivascular adipose tissues.
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Am J Physiol Regul Integr Comp Physiol
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2013
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1.08
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29
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Exercise training preserves endothelium-dependent relaxation in brachial arteries from hyperlipidemic pigs.
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J Appl Physiol (1985)
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2003
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1.07
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30
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Physical activity maintains aortic endothelium-dependent relaxation in the obese type 2 diabetic OLETF rat.
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Am J Physiol Heart Circ Physiol
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2010
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1.06
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31
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Decreased NO signaling leads to enhanced vasoconstrictor responsiveness in skeletal muscle arterioles of the ZDF rat prior to overt diabetes and hypertension.
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Am J Physiol Heart Circ Physiol
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2008
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1.06
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32
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Daily physical activity enhances reactivity to insulin in skeletal muscle arterioles of hyperphagic Otsuka Long-Evans Tokushima Fatty rats.
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J Appl Physiol (1985)
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2010
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1.06
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33
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Altered mechanism of adenosine-induced coronary arteriolar dilation in early-stage metabolic syndrome.
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Exp Biol Med (Maywood)
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2009
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1.05
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34
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Relationship between upper and lower limb conduit artery vasodilator function in humans.
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J Appl Physiol (1985)
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2011
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1.03
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35
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The effects of acute and chronic exercise on the vasculature.
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Acta Physiol (Oxf)
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2010
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1.03
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36
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Alpha-adrenergic inhibition increases collateral circuit conductance in rats following acute occlusion of the femoral artery.
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J Physiol
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2008
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1.02
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37
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Alpha-adrenergic and neuropeptide Y Y1 receptor control of collateral circuit conductance: influence of exercise training.
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J Physiol
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2008
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1.02
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38
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Impact of aging on conduit artery retrograde and oscillatory shear at rest and during exercise: role of nitric oxide.
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Hypertension
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2011
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1.00
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39
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Exercise attenuates the effects of hypercholesterolemia on endothelium-dependent relaxation in coronary arteries from adult female pigs.
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J Appl Physiol (1985)
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2003
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0.99
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40
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Vascular nitric oxide: effects of exercise training in animals.
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Appl Physiol Nutr Metab
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2008
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0.99
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41
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Endothelial function in coronary arterioles from pigs with early-stage coronary disease induced by high-fat, high-cholesterol diet: effect of exercise.
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J Appl Physiol (1985)
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2004
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0.99
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42
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Exercise training does not reduce hyperlipidemia in pigs fed a high-fat diet.
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Metabolism
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2002
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0.98
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43
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Exercise training does not increase muscle FNDC5 protein or mRNA expression in pigs.
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Metabolism
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2013
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0.97
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44
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Prior exercise training produces NO-dependent increases in collateral blood flow after acute arterial occlusion.
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Am J Physiol Heart Circ Physiol
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2002
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0.97
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45
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Effects of chronic nitric oxide synthase inhibition on responses to acute exercise in swine.
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J Appl Physiol (1985)
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2007
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0.97
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46
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Long-term exercise training does not alter brachial and femoral artery vasomotor function and endothelial phenotype in healthy pigs.
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Am J Physiol Heart Circ Physiol
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2010
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0.96
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47
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Combining metformin and aerobic exercise training in the treatment of type 2 diabetes and NAFLD in OLETF rats.
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Am J Physiol Endocrinol Metab
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2013
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0.96
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48
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Exercise-induced Signals for Vascular Endothelial Adaptations: Implications for Cardiovascular Disease.
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Curr Cardiovasc Risk Rep
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2012
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0.95
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49
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Adipose tissue and vascular phenotypic modulation by voluntary physical activity and dietary restriction in obese insulin-resistant OLETF rats.
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Am J Physiol Regul Integr Comp Physiol
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2014
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0.95
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50
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Exercise training improves femoral artery blood flow responses to endothelium-dependent dilators in hypercholesterolemic pigs.
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Am J Physiol Heart Circ Physiol
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2006
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0.94
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51
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Epicardial fat gene expression after aerobic exercise training in pigs with coronary atherosclerosis: relationship to visceral and subcutaneous fat.
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J Appl Physiol (1985)
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2010
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0.94
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52
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Pro-atherogenic shear rate patterns in the femoral artery of healthy older adults.
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Atherosclerosis
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2010
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0.93
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53
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C-reactive protein correlates with macrophage accumulation in coronary arteries of hypercholesterolemic pigs.
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J Appl Physiol (1985)
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2003
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0.93
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54
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Low-fat diet and exercise preserve eNOS regulation and endothelial function in the penis of early atherosclerotic pigs: a molecular analysis.
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J Sex Med
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2008
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0.93
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55
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Endurance exercise training improves endothelium-dependent relaxation in brachial arteries from hypercholesterolemic male pigs.
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J Appl Physiol (1985)
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2005
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0.93
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56
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Endothelium-dependent and -independent relaxation in the forelimb and hindlimb vasculatures of swine.
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Comp Biochem Physiol A Mol Integr Physiol
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2007
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0.93
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57
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Short-term increases in intraluminal pressure reverse age-related decrements in endothelium-dependent dilation in soleus muscle feed arteries.
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J Appl Physiol (1985)
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2007
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0.92
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58
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Intermittent pneumatic leg compressions acutely upregulate VEGF and MCP-1 expression in skeletal muscle.
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Am J Physiol Heart Circ Physiol
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2010
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0.91
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59
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Exercise training enhances vasodilation responses to vascular endothelial growth factor in porcine coronary arterioles exposed to chronic coronary occlusion.
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Circulation
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2004
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0.91
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60
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Familial hypercholesterolemia impairs exercise-induced systemic vasodilation due to reduced NO bioavailability.
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J Appl Physiol (1985)
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2013
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0.91
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61
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Functional adaptations in the skeletal muscle microvasculature to endurance and interval sprint training in the type 2 diabetic OLETF rat.
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J Appl Physiol (1985)
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2012
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0.90
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62
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Vascular nitric oxide: effects of physical activity, importance for health.
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Essays Biochem
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2006
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0.90
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63
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Differential changes in vascular mRNA levels between rat iliac and renal arteries produced by cessation of voluntary running.
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Exp Physiol
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2012
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0.90
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64
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The muscle pump: what question do we want to answer?
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J Appl Physiol (1985)
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2005
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0.90
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65
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Epicardial adipose excision slows the progression of porcine coronary atherosclerosis.
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J Cardiothorac Surg
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2014
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0.90
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66
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Reduced contribution of endothelin to the regulation of systemic and pulmonary vascular tone in severe familial hypercholesterolaemia.
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J Physiol
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2014
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0.90
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67
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Hypercholesterolemia increases mitochondrial oxidative stress and enhances the MPT response in the porcine myocardium: beneficial effects of chronic exercise.
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Am J Physiol Regul Integr Comp Physiol
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2011
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0.89
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68
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Modulating fibroblast growth factor 21 in hyperphagic OLETF rats with daily exercise and caloric restriction.
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Appl Physiol Nutr Metab
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2012
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0.89
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69
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Proceedings of the Conference on Swine in Biomedical Research.
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ILAR J
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2009
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0.89
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70
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Computational network model prediction of hemodynamic alterations due to arteriolar remodeling in interval sprint trained skeletal muscle.
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Microcirculation
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2007
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0.89
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71
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Perivascular fat alters reactivity of coronary artery: effects of diet and exercise.
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Med Sci Sports Exerc
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2007
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0.89
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72
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Transcriptome-wide RNA sequencing analysis of rat skeletal muscle feed arteries. II. Impact of exercise training in obesity.
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J Appl Physiol (1985)
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2014
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0.89
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73
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Chronic nitric oxide synthase inhibition blunts endothelium-dependent function of conduit coronary arteries, not arterioles.
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Am J Physiol Heart Circ Physiol
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2007
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0.88
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74
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Vasoresponsiveness of collateral vessels in the rat hindlimb: influence of training.
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J Physiol
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2010
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0.88
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75
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Impact of exercise training on endothelial transcriptional profiles in healthy swine: a genome-wide microarray analysis.
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Am J Physiol Heart Circ Physiol
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2011
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0.88
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76
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Transcriptome-wide RNA sequencing analysis of rat skeletal muscle feed arteries. I. Impact of obesity.
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J Appl Physiol (1985)
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2014
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0.87
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77
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Vascular transcriptional alterations produced by juvenile obesity in Ossabaw swine.
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Physiol Genomics
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2013
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0.87
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78
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Exercise does not attenuate early CAD progression in a pig model.
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Med Sci Sports Exerc
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2012
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0.86
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79
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Sex difference in link between interleukin-6 and stress.
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Endocrinology
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2007
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0.86
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80
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Structural adaptation increases predicted perfusion capacity after vessel obstruction in arteriolar arcade network of pig skeletal muscle.
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Am J Physiol Heart Circ Physiol
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2005
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0.85
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81
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Differential vasomotor effects of insulin on gastrocnemius and soleus feed arteries in the OLETF rat model: role of endothelin-1.
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Exp Physiol
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2013
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0.85
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82
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Exercise training alters effect of high-fat feeding on the ACTH stress response in pigs.
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Appl Physiol Nutr Metab
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2008
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0.84
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83
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Blood pressure regulation VIII: resistance vessel tone and implications for a pro-atherogenic conduit artery endothelial cell phenotype.
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Eur J Appl Physiol
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2013
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0.84
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84
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Potential clinical translation of juvenile rodent inactivity models to study the onset of childhood obesity.
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Am J Physiol Regul Integr Comp Physiol
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2012
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0.84
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85
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Hepatic steatosis development with four weeks of physical inactivity in previously active, hyperphagic OLETF rats.
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Am J Physiol Regul Integr Comp Physiol
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2013
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0.84
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86
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Closer to the edge? Contractions, pressures, waterfalls and blood flow to contracting skeletal muscle.
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J Appl Physiol (1985)
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2003
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0.83
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87
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Regulation of nitric oxide-dependent vasodilation in coronary arteries of estrogen receptor-alpha-deficient mice.
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Am J Physiol Heart Circ Physiol
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2003
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0.83
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88
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Treating NAFLD in OLETF rats with vigorous-intensity interval exercise training.
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Med Sci Sports Exerc
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2015
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0.83
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89
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Maintaining patency and asepsis of vascular access ports in Yucatan miniature swine.
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Contemp Top Lab Anim Sci
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2003
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0.82
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90
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Heterogeneity of endothelial cell phenotype within and amongst conduit vessels of the swine vasculature.
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Exp Physiol
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2012
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0.82
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91
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Relationship between brachial and femoral artery endothelial vasomotor function/phenotype in pigs.
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Exp Biol Med (Maywood)
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2010
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0.82
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92
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Reduced hepatic eNOS phosphorylation is associated with NAFLD and type 2 diabetes progression and is prevented by daily exercise in hyperphagic OLETF rats.
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J Appl Physiol (1985)
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2014
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0.81
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93
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Functional contribution of P2Y1 receptors to the control of coronary blood flow.
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J Appl Physiol (1985)
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2011
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0.80
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94
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Effects of gradual coronary artery occlusion and exercise training on gene expression in swine heart.
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Mol Cell Biochem
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2006
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0.80
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95
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Gene expression differences during the heterogeneous progression of peripheral atherosclerosis in familial hypercholesterolemic swine.
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BMC Genomics
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2013
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0.80
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96
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Exercise limits the production of endothelin in the coronary vasculature.
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Am J Physiol Heart Circ Physiol
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2011
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0.80
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97
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New insights into the physiologic basis for intermittent pneumatic limb compression as a therapeutic strategy for peripheral artery disease.
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J Vasc Surg
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2013
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0.78
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98
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Chronic inhibition of nitric oxide synthase augments the ACTH response to exercise.
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Am J Physiol Regul Integr Comp Physiol
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2009
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0.78
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99
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Placentation in the pig visualized by eGFP fluorescence in eNOS over-expressing cloned transgenic swine.
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Mol Reprod Dev
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2010
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0.78
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100
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Evaluation of transcutaneous Doppler ultrasonography for the measurement of blood flow in the femoral artery of pigs.
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Am J Vet Res
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2003
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0.78
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101
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Exercise training and vascular cell phenotype in a swine model of familial hypercholesterolaemia: conduit arteries and veins.
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Exp Physiol
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2013
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0.78
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102
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Effects of high-density lipoprotein on endothelium-dependent vasorelaxation.
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Appl Physiol Nutr Metab
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2010
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0.78
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103
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Phosphodiesterase-5 activity exerts a coronary vasoconstrictor influence in awake swine that is mediated in part via an increase in endothelin production.
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Am J Physiol Heart Circ Physiol
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2014
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0.78
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104
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Influence of regular physical activity and caloric restriction on β-adrenergic and natriuretic peptide receptor expression in retroperitoneal adipose tissue of OLETF rats.
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Exp Physiol
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2013
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0.77
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105
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Pulmonary vasoconstrictor influence of endothelin in exercising swine depends critically on phosphodiesterase 5 activity.
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Am J Physiol Lung Cell Mol Physiol
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2014
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0.76
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106
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Mechanisms of flow and ACh-induced dilation in rat soleus arterioles are altered by hindlimb unweighting.
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J Appl Physiol (1985)
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2002
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0.76
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107
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Upregulation of cyclooxygenase-2 expression in porcine macula densa with chronic nitric oxide synthase inhibition.
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Vet Pathol
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2010
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0.75
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108
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Comments on point: counterpoint: exercise training does/does not induce vascular adaptations beyond the active muscle beds.
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J Appl Physiol (1985)
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2008
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0.75
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109
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Exercise Training As A Mitigator Of Liver Fibrosis In Western Diet Fed OLETF Rats: 1783 Board #3 June 2, 1: 00 PM - 3: 00 PM.
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Med Sci Sports Exerc
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2016
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0.75
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