Published in J Am Chem Soc on November 17, 2004
Protein folding studied by single-molecule FRET. Curr Opin Struct Biol (2008) 4.33
Reaction coordinates and rates from transition paths. Proc Natl Acad Sci U S A (2005) 3.12
Single-molecule fluorescence studies of protein folding and conformational dynamics. Chem Rev (2006) 3.08
Polyproline and the "spectroscopic ruler" revisited with single-molecule fluorescence. Proc Natl Acad Sci U S A (2005) 3.01
Experimental determination of upper bound for transition path times in protein folding from single-molecule photon-by-photon trajectories. Proc Natl Acad Sci U S A (2009) 2.29
Single-molecule biophysics: at the interface of biology, physics and chemistry. J R Soc Interface (2008) 2.06
Single-molecule Forster resonance energy transfer study of protein dynamics under denaturing conditions. Proc Natl Acad Sci U S A (2005) 2.02
Direct observation of abortive initiation and promoter escape within single immobilized transcription complexes. Biophys J (2005) 1.90
Protein folding is slaved to solvent motions. Proc Natl Acad Sci U S A (2006) 1.88
Full distance-resolved folding energy landscape of one single protein molecule. Proc Natl Acad Sci U S A (2010) 1.85
Effect of flexibility and cis residues in single-molecule FRET studies of polyproline. Proc Natl Acad Sci U S A (2007) 1.81
DNA folding and melting observed in real time redefine the energy landscape. Proc Natl Acad Sci U S A (2007) 1.56
Effects of denaturants and osmolytes on proteins are accurately predicted by the molecular transfer model. Proc Natl Acad Sci U S A (2008) 1.52
An expanding arsenal of experimental methods yields an explosion of insights into protein folding mechanisms. Nat Struct Mol Biol (2009) 1.43
Single-molecule fluorescence spectroscopy maps the folding landscape of a large protein. Nat Commun (2011) 1.30
Dynamics of heat shock protein 90 C-terminal dimerization is an important part of its conformational cycle. Proc Natl Acad Sci U S A (2010) 1.17
Single-molecule FRET of protein-nucleic acid and protein-protein complexes: surface passivation and immobilization. Methods (2010) 1.11
Single molecule characterization of α-synuclein in aggregation-prone states. Biophys J (2010) 1.09
Energy landscape and multiroute folding of topologically complex proteins adenylate kinase and 2ouf-knot. Proc Natl Acad Sci U S A (2012) 1.02
How accurate are polymer models in the analysis of Förster resonance energy transfer experiments on proteins? J Chem Phys (2009) 1.02
Calmodulin, conformational states, and calcium signaling. A single-molecule perspective. Biochemistry (2006) 0.99
How long does it take to equilibrate the unfolded state of a protein? Protein Sci (2013) 0.95
Microfluidic mixer designed for performing single-molecule kinetics with confocal detection on timescales from milliseconds to minutes. Nat Protoc (2013) 0.94
FRET efficiency distributions of multistate single molecules. J Phys Chem B (2010) 0.93
Direct observation of markovian behavior of the mechanical unfolding of individual proteins. Biophys J (2008) 0.92
Similarity and difference in the unfolding of thermophilic and mesophilic cold shock proteins studied by molecular dynamics simulations. Biophys J (2006) 0.91
Nanovesicle trapping for studying weak protein interactions by single-molecule FRET. Methods Enzymol (2010) 0.90
Probing the origins of two-state folding. J Chem Phys (2013) 0.90
A simple model predicts experimental folding rates and a hub-like topology. J Phys Chem B (2012) 0.90
Interaction Networks in Protein Folding via Atomic-Resolution Experiments and Long-Time-Scale Molecular Dynamics Simulations. J Am Chem Soc (2015) 0.87
Fast protein folding kinetics. Q Rev Biophys (2014) 0.86
Protein folding at single-molecule resolution. Biochim Biophys Acta (2011) 0.86
Tracking unfolding and refolding of single GFPmut2 molecules. Biophys J (2005) 0.86
Nanotools for megaproblems: probing protein misfolding diseases using nanomedicine modus operandi. J Proteome Res (2006) 0.85
Single-molecule FRET of protein structure and dynamics - a primer. J Nanobiotechnology (2013) 0.85
Unraveling electronic energy transfer in single conjugated polyelectrolytes encapsulated in lipid vesicles. Proc Natl Acad Sci U S A (2010) 0.83
Tackling metal regulation and transport at the single-molecule level. Nat Prod Rep (2010) 0.83
Effects of pH on proteins: predictions for ensemble and single-molecule pulling experiments. J Am Chem Soc (2011) 0.83
Mapping the energy landscape for second-stage folding of a single membrane protein. Nat Chem Biol (2015) 0.82
Is there an en route folding intermediate for Cold shock proteins? Protein Sci (2012) 0.82
Dodine as a protein denaturant: the best of two worlds? J Phys Chem B (2013) 0.80
Fluorescence of Alexa fluor dye tracks protein folding. PLoS One (2012) 0.79
Reconciling Intermediates in Mechanical Unfolding Experiments with Two-State Protein Folding in Bulk. J Phys Chem Lett (2016) 0.76
Quantitative interpretation of FRET experiments via molecular simulation: force field and validation. Biophys J (2015) 0.75
Simultaneous Determination of Two Subdomain Folding Rates Using the "Transfer-Quench" Method. Biophys J (2017) 0.75
Rise-time of FRET-acceptor fluorescence tracks protein folding. Int J Mol Sci (2014) 0.75
T4 lysozyme as a Pac-Man: how fast can it chew? Biophys J (2012) 0.75
Single-Molecule Analysis of Cytochrome c Folding by Monitoring the Lifetime of an Attached Fluorescent Probe. J Phys Chem Lett (2013) 0.75
How cooperative are protein folding and unfolding transitions? Protein Sci (2016) 0.75
A simple two-state protein unfolds mechanically via multiple heterogeneous pathways at single-molecule resolution. Nat Commun (2016) 0.75
Observation of protein folding/unfolding dynamics of ubiquitin trapped in agarose gel by single-molecule FRET. Eur Biophys J (2011) 0.75
First passage, looping, and direct transition in expanding and narrowing tubes: Effects of the entropy potential. J Chem Phys (2017) 0.75
Watching proteins fold one molecule at a time. Proc Natl Acad Sci U S A (2003) 3.25
Single-molecule measurement of protein folding kinetics. Science (2003) 3.08
Ultrafast dynamics of protein collapse from single-molecule photon statistics. Proc Natl Acad Sci U S A (2007) 2.76
Mapping protein collapse with single-molecule fluorescence and kinetic synchrotron radiation circular dichroism spectroscopy. Proc Natl Acad Sci U S A (2006) 2.48
From the Cover: Charge interactions can dominate the dimensions of intrinsically disordered proteins. Proc Natl Acad Sci U S A (2010) 2.37
Coil-globule transition in the denatured state of a small protein. Proc Natl Acad Sci U S A (2006) 2.27
Assessing computational methods for predicting protein stability upon mutation: good on average but not in the details. Protein Eng Des Sel (2009) 2.25
Effect of flexibility and cis residues in single-molecule FRET studies of polyproline. Proc Natl Acad Sci U S A (2007) 1.81
Quantifying internal friction in unfolded and intrinsically disordered proteins with single-molecule spectroscopy. Proc Natl Acad Sci U S A (2012) 1.64
The molecular architecture of protein-protein binding sites. Curr Opin Struct Biol (2007) 1.59
Effects of denaturants and osmolytes on proteins are accurately predicted by the molecular transfer model. Proc Natl Acad Sci U S A (2008) 1.52
Single-molecule spectroscopy of the temperature-induced collapse of unfolded proteins. Proc Natl Acad Sci U S A (2009) 1.52
Unfolded protein and peptide dynamics investigated with single-molecule FRET and correlation spectroscopy from picoseconds to seconds. J Phys Chem B (2008) 1.48
Collapse transition in proteins. Phys Chem Chem Phys (2008) 1.41
Community-wide assessment of protein-interface modeling suggests improvements to design methodology. J Mol Biol (2011) 1.40
Protein-protein association in polymer solutions: from dilute to semidilute to concentrated. Biophys J (2006) 1.40
Separating the contribution of translational and rotational diffusion to protein association. J Am Chem Soc (2005) 1.39
Single-molecule spectroscopy of protein folding in a chaperonin cage. Proc Natl Acad Sci U S A (2010) 1.37
Single-molecule fluorescence reveals sequence-specific misfolding in multidomain proteins. Nature (2011) 1.37
Ribosome exit tunnel can entropically stabilize alpha-helices. Proc Natl Acad Sci U S A (2005) 1.36
Polymer scaling laws of unfolded and intrinsically disordered proteins quantified with single-molecule spectroscopy. Proc Natl Acad Sci U S A (2012) 1.34
Common crowding agents have only a small effect on protein-protein interactions. Biophys J (2009) 1.33
Single-molecule fluorescence spectroscopy maps the folding landscape of a large protein. Nat Commun (2011) 1.30
Role of solvation effects in protein denaturation: from thermodynamics to single molecules and back. Annu Rev Phys Chem (2011) 1.27
Recognition of helical kinks by xeroderma pigmentosum group A protein triggers DNA excision repair. Nat Struct Mol Biol (2006) 1.24
Probing protein-chaperone interactions with single-molecule fluorescence spectroscopy. Angew Chem Int Ed Engl (2008) 1.23
Kinetics of intramolecular contact formation in a denatured protein. J Mol Biol (2003) 1.22
Structural heterogeneity and quantitative FRET efficiency distributions of polyprolines through a hybrid atomistic simulation and Monte Carlo approach. PLoS One (2011) 1.16
Protein folding, protein collapse, and tanford's transfer model: lessons from single-molecule FRET. J Am Chem Soc (2009) 1.13
Localizing internal friction along the reaction coordinate of protein folding by combining ensemble and single-molecule fluorescence spectroscopy. Nat Commun (2012) 1.13
Using fluorescence correlation spectroscopy to study conformational changes in denatured proteins. Biophys J (2008) 1.13
The dynamic disulphide relay of quiescin sulphydryl oxidase. Nature (2012) 1.06
Single-molecule spectroscopy reveals polymer effects of disordered proteins in crowded environments. Proc Natl Acad Sci U S A (2014) 1.03
Biophysical characterization of the unstructured cytoplasmic domain of the human neuronal adhesion protein neuroligin 3. Biophys J (2008) 1.03
On the dynamic nature of the transition state for protein-protein association as determined by double-mutant cycle analysis and simulation. J Mol Biol (2007) 1.01
Multiple-particle nanoantennas for enormous enhancement and polarization control of light emission. ACS Nano (2009) 0.99
Protein dynamics from single-molecule fluorescence intensity correlation functions. J Chem Phys (2009) 0.99
Quantifying heterogeneity and conformational dynamics from single molecule FRET of diffusing molecules: recurrence analysis of single particles (RASP). Phys Chem Chem Phys (2011) 0.98
Managing light polarization via plasmon-molecule interactions within an asymmetric metal nanoparticle trimer. Proc Natl Acad Sci U S A (2008) 0.98
Small-angle X-ray scattering and single-molecule FRET spectroscopy produce highly divergent views of the low-denaturant unfolded state. J Mol Biol (2012) 0.97
Chemical denaturants inhibit the onset of dewetting. J Am Chem Soc (2008) 0.97
Temperature-dependent solvation modulates the dimensions of disordered proteins. Proc Natl Acad Sci U S A (2014) 0.96
Noncovalent, site-specific biotinylation of histidine-tagged proteins. Anal Chem (2007) 0.96
Microfluidic mixer designed for performing single-molecule kinetics with confocal detection on timescales from milliseconds to minutes. Nat Protoc (2013) 0.94
Microfluidic mixers for the investigation of rapid protein folding kinetics using synchrotron radiation circular dichroism spectroscopy. Anal Chem (2008) 0.93
Non-random-coil behavior as a consequence of extensive PPII structure in the denatured state. J Mol Biol (2008) 0.92
Detection and analysis of protein aggregation with confocal single molecule fluorescence spectroscopy. J Fluoresc (2007) 0.92
Single-molecule studies of intrinsically disordered proteins. Chem Rev (2014) 0.91
Cryogenic colocalization microscopy for nanometer-distance measurements. Chemphyschem (2014) 0.89
Trimeric plasmonic molecules: the role of symmetry. Nano Lett (2011) 0.89
Concerted ATP-induced allosteric transitions in GroEL facilitate release of protein substrate domains in an all-or-none manner. Proc Natl Acad Sci U S A (2007) 0.88
Out-of-equilibrium conformational cycling of GroEL under saturating ATP concentrations. Proc Natl Acad Sci U S A (2010) 0.87
Single-molecule FRET of protein structure and dynamics - a primer. J Nanobiotechnology (2013) 0.85
Probing the Raman scattering tensors of individual molecules. J Phys Chem B (2006) 0.85
Temperature-cycle single-molecule FRET microscopy on polyprolines. Phys Chem Chem Phys (2010) 0.85
Single-molecule spectroscopy of cold denaturation and the temperature-induced collapse of unfolded proteins. J Am Chem Soc (2013) 0.84
Fluorescence correlation spectroscopy of fast chain dynamics within denatured protein L. Chemphyschem (2011) 0.84
Maximal Raman optical activity in hybrid single molecule-plasmonic nanostructures with multiple dipolar resonances. Nano Lett (2013) 0.84
Protein structure modelling and evaluation based on a 4-distance description of side-chain interactions. BMC Bioinformatics (2010) 0.83
Characterization of variants of the pore-forming toxin ClyA from Escherichia coli controlled by a redox switch. Biochemistry (2014) 0.82
Design of an optical switch for studying conformational dynamics in individual molecules of GroEL. Bioconjug Chem (2008) 0.82
Free energy surfaces from single-distance information. J Phys Chem B (2010) 0.82
Concerted release of substrate domains from GroEL by ATP is demonstrated with FRET. J Mol Biol (2008) 0.82
Thermodynamic analysis of the dissociation of the aldolase tetramer substituted at one or both of the subunit interfaces. Biol Chem (2003) 0.81
Allosteric inhibition of individual enzyme molecules trapped in lipid vesicles. Proc Natl Acad Sci U S A (2012) 0.81
Intramolecular distances and dynamics from the combined photon statistics of single-molecule FRET and photoinduced electron transfer. J Phys Chem B (2013) 0.81
Consistent View of Polypeptide Chain Expansion in Chemical Denaturants from Multiple Experimental Methods. J Am Chem Soc (2016) 0.79
Single-particle tracking reveals switching of the HIV fusion peptide between two diffusive modes in membranes. J Phys Chem B (2013) 0.79
Correlating electron tomography and plasmon spectroscopy of single noble metal core-shell nanoparticles. Nano Lett (2011) 0.79
Experimental and computational study of BODIPY dye-labeled cavitand dynamics. J Am Chem Soc (2014) 0.79
Raman spectroelectrochemistry of molecules within individual electromagnetic hot spots. J Am Chem Soc (2009) 0.79
Detection and quantification through a lipid membrane using the molecularly controlled semiconductor resistor. Langmuir (2011) 0.78
To fold or expand--a charged question. Proc Natl Acad Sci U S A (2010) 0.78
Observation of calcium-dependent unidirectional rotational motion in recombinant photosynthetic F1-ATPase molecules. J Biol Chem (2004) 0.77
Single-molecule spectroscopy of the unexpected collapse of an unfolded protein at low pH. J Chem Phys (2013) 0.76
Characterization of the unfolded state of repeat proteins. HFSP J (2008) 0.75
Modular plasmonic antennas built of ultrathin silica-shell silver-core nanoparticles. Langmuir (2014) 0.75
Quantifying Kinetics from Time Series of Single-Molecule FRET Efficiency Histograms. Nanotechnology (2017) 0.75
Erratum: The assembly dynamics of the cytolytic pore toxin ClyA. Nat Commun (2016) 0.75
The coming of age. Chemphyschem (2005) 0.75
Can a rare form of myasthenia gravis shed additional light on disease mechanisms? Clin Neurol Neurosurg (2012) 0.75
Optical spectroscopy of biomolecular dynamics. Chemphyschem (2004) 0.75
Temperature-cycle microscopy reveals single-molecule conformational heterogeneity. Phys Chem Chem Phys (2015) 0.75
Fluorescence correlation spectroscopy and allostery: the case of GroEL. Methods Mol Biol (2012) 0.75