Donald Y M Leung

Author PubWeight™ 193.50‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Endogenous antimicrobial peptides and skin infections in atopic dermatitis. N Engl J Med 2002 9.01
2 Genome sequence of a serotype M3 strain of group A Streptococcus: phage-encoded toxins, the high-virulence phenotype, and clone emergence. Proc Natl Acad Sci U S A 2002 5.07
3 Cytokine milieu of atopic dermatitis, as compared to psoriasis, skin prevents induction of innate immune response genes. J Immunol 2003 3.41
4 Filaggrin mutations associated with skin and allergic diseases. N Engl J Med 2011 3.40
5 Cytokine milieu of atopic dermatitis skin subverts the innate immune response to vaccinia virus. Immunity 2006 3.39
6 Decreased serum vitamin D levels in children with asthma are associated with increased corticosteroid use. J Allergy Clin Immunol 2010 3.22
7 Cytokine modulation of atopic dermatitis filaggrin skin expression. J Allergy Clin Immunol 2007 2.79
8 Atopic dermatitis: a disease of altered skin barrier and immune dysregulation. Immunol Rev 2011 2.62
9 Vitamin D levels, lung function, and steroid response in adult asthma. Am J Respir Crit Care Med 2010 2.40
10 Vitamin D inhibits monocyte/macrophage proinflammatory cytokine production by targeting MAPK phosphatase-1. J Immunol 2012 2.27
11 Filaggrin mutations that confer risk of atopic dermatitis confer greater risk for eczema herpeticum. J Allergy Clin Immunol 2009 2.20
12 Recent insights into atopic dermatitis and implications for management of infectious complications. J Allergy Clin Immunol 2010 2.20
13 Selective killing of vaccinia virus by LL-37: implications for eczema vaccinatum. J Immunol 2004 2.16
14 Cytokines and chemokines orchestrate atopic skin inflammation. J Allergy Clin Immunol 2006 2.08
15 Polarized in vivo expression of IL-11 and IL-17 between acute and chronic skin lesions. J Allergy Clin Immunol 2003 2.05
16 Superantigen-induced corticosteroid resistance of human T cells occurs through activation of the mitogen-activated protein kinase kinase/extracellular signal-regulated kinase (MEK-ERK) pathway. J Allergy Clin Immunol 2004 2.00
17 Phenotype of atopic dermatitis subjects with a history of eczema herpeticum. J Allergy Clin Immunol 2009 2.00
18 Diagnosis and treatment of atopic dermatitis in children and adults: European Academy of Allergology and Clinical Immunology/American Academy of Allergy, Asthma and Immunology/PRACTALL Consensus Report. J Allergy Clin Immunol 2006 2.00
19 Maternal consumption of peanut during pregnancy is associated with peanut sensitization in atopic infants. J Allergy Clin Immunol 2010 1.97
20 Cathelicidin deficiency predisposes to eczema herpeticum. J Allergy Clin Immunol 2006 1.88
21 Characterization of a hapten-induced, murine model with multiple features of atopic dermatitis: structural, immunologic, and biochemical changes following single versus multiple oxazolone challenges. J Invest Dermatol 2007 1.85
22 Structure-function relationships among human cathelicidin peptides: dissociation of antimicrobial properties from host immunostimulatory activities. J Immunol 2005 1.78
23 Tight junction defects in patients with atopic dermatitis. J Allergy Clin Immunol 2010 1.77
24 Loricrin and involucrin expression is down-regulated by Th2 cytokines through STAT-6. Clin Immunol 2007 1.77
25 Body mass and glucocorticoid response in asthma. Am J Respir Crit Care Med 2008 1.68
26 Immune mechanisms leading to atopic dermatitis. J Allergy Clin Immunol 2003 1.66
27 Smallpox vaccination: Risk considerations for patients with atopic dermatitis. J Allergy Clin Immunol 2002 1.60
28 Risk assessment in anaphylaxis: current and future approaches. J Allergy Clin Immunol 2007 1.57
29 Cluster analysis of obesity and asthma phenotypes. PLoS One 2012 1.56
30 IL-4 and IL-13 negatively regulate TNF-alpha- and IFN-gamma-induced beta-defensin expression through STAT-6, suppressor of cytokine signaling (SOCS)-1, and SOCS-3. J Immunol 2007 1.55
31 Ceragenins: a class of antiviral compounds to treat orthopox infections. J Invest Dermatol 2009 1.55
32 Interleukin-10 downregulates anti-microbial peptide expression in atopic dermatitis. J Invest Dermatol 2005 1.54
33 Increased glucocorticoid receptor beta alters steroid response in glucocorticoid-insensitive asthma. Am J Respir Crit Care Med 2005 1.53
34 IL-4 regulates skin homeostasis and the predisposition toward allergic skin inflammation. J Immunol 2010 1.49
35 Staphylococcal and streptococcal superantigen exotoxins. Clin Microbiol Rev 2013 1.48
36 10. Atopic dermatitis. J Allergy Clin Immunol 2006 1.48
37 The role of allergens in asthma. Am Fam Physician 2007 1.47
38 Advances in allergic skin disease, anaphylaxis, and hypersensitivity reactions to foods, drugs, and insects in 2007. J Allergy Clin Immunol 2008 1.46
39 Corticosteroid-resistant asthma is associated with classical antimicrobial activation of airway macrophages. J Allergy Clin Immunol 2008 1.44
40 Vitamin D in atopic dermatitis, asthma and allergic diseases. Immunol Allergy Clin North Am 2010 1.43
41 Secreted virulence factor comparison between methicillin-resistant and methicillin-sensitive Staphylococcus aureus, and its relevance to atopic dermatitis. J Allergy Clin Immunol 2010 1.42
42 Mechanism of HBD-3 deficiency in atopic dermatitis. Clin Immunol 2006 1.40
43 Cytokine modulation of atopic dermatitis filaggrin skin expression. J Allergy Clin Immunol 2009 1.38
44 Genetic variants in thymic stromal lymphopoietin are associated with atopic dermatitis and eczema herpeticum. J Allergy Clin Immunol 2010 1.38
45 IL-31 is associated with cutaneous lymphocyte antigen-positive skin homing T cells in patients with atopic dermatitis. J Allergy Clin Immunol 2006 1.37
46 T regulatory cells in atopic dermatitis and subversion of their activity by superantigens. J Allergy Clin Immunol 2004 1.36
47 The effects of airway microbiome on corticosteroid responsiveness in asthma. Am J Respir Crit Care Med 2013 1.36
48 The constitutive capacity of human keratinocytes to kill Staphylococcus aureus is dependent on beta-defensin 3. J Invest Dermatol 2007 1.32
49 A phase II, randomized, double‑blind, parallel‑group, placebo‑controlled oral food challenge trial of Xolair (omalizumab) in peanut allergy. J Allergy Clin Immunol 2011 1.30
50 Atopic dermatitis and asthma: parallels in the evolution of treatment. Pediatrics 2003 1.30
51 Immune dysregulation in atopic dermatitis. Curr Allergy Asthma Rep 2006 1.29
52 Th2 cytokines act on S100/A11 to downregulate keratinocyte differentiation. J Invest Dermatol 2008 1.27
53 Allergic skin diseases. J Allergy Clin Immunol 2009 1.25
54 Immunologic features of infants with milk or egg allergy enrolled in an observational study (Consortium of Food Allergy Research) of food allergy. J Allergy Clin Immunol 2010 1.25
55 Vaccinia virus inoculation in sites of allergic skin inflammation elicits a vigorous cutaneous IL-17 response. Proc Natl Acad Sci U S A 2009 1.23
56 Characterization of a novel staphylococcal enterotoxin-like superantigen, a member of the group V subfamily of pyrogenic toxins. Biochemistry 2002 1.23
57 Timing of initial exposure to cereal grains and the risk of wheat allergy. Pediatrics 2006 1.22
58 Steroid requirements and immune associations with vitamin D are stronger in children than adults with asthma. J Allergy Clin Immunol 2012 1.22
59 Superantigen profile of Staphylococcus aureus isolates from patients with steroid-resistant atopic dermatitis. Clin Infect Dis 2008 1.22
60 TNF-α downregulates filaggrin and loricrin through c-Jun N-terminal kinase: role for TNF-α antagonists to improve skin barrier. J Invest Dermatol 2011 1.18
61 Defective killing of Staphylococcus aureus in atopic dermatitis is associated with reduced mobilization of human beta-defensin-3. J Allergy Clin Immunol 2008 1.17
62 Disease severity, scratching, and sleep quality in patients with atopic dermatitis. J Am Acad Dermatol 2008 1.15
63 Report of the Topical Calcineurin Inhibitor Task Force of the American College of Allergy, Asthma and Immunology and the American Academy of Allergy, Asthma and Immunology. J Allergy Clin Immunol 2005 1.14
64 A role for STAT5 in the pathogenesis of IL-2-induced glucocorticoid resistance. J Immunol 2002 1.13
65 Airway remodeling and lack of bronchodilator response in steroid-resistant asthma. J Allergy Clin Immunol 2007 1.13
66 Characterization of Staphylococcus aureus enterotoxin L. Infect Immun 2003 1.13
67 Staphylococcal enterotoxin B inhibits regulatory T cells by inducing glucocorticoid-induced TNF receptor-related protein ligand on monocytes. J Allergy Clin Immunol 2006 1.11
68 Estrogen inhibits glucocorticoid action via protein phosphatase 5 (PP5)-mediated glucocorticoid receptor dephosphorylation. J Biol Chem 2009 1.10
69 Vitamin D and food allergy in patients with severe atopic dermatitis. J Allergy Clin Immunol 2013 1.10
70 Macrophage inflammatory protein 3alpha deficiency in atopic dermatitis skin and role in innate immune response to vaccinia virus. J Allergy Clin Immunol 2006 1.09
71 Comparative proteomic profiling of patients with atopic dermatitis based on history of eczema herpeticum infection and Staphylococcus aureus colonization. J Allergy Clin Immunol 2011 1.08
72 Renaissance of the hygiene hypothesis. J Allergy Clin Immunol 2006 1.07
73 Impaired immune response to vaccinia virus inoculated at the site of cutaneous allergic inflammation. J Allergy Clin Immunol 2007 1.05
74 Role of bacterial superantigens in atopic dermatitis : implications for future therapeutic strategies. Am J Clin Dermatol 2006 1.05
75 Immunopathology of atopic dermatitis. J Allergy Clin Immunol 2006 1.05
76 Oral food challenges in children with a diagnosis of food allergy. J Pediatr 2010 1.03
77 Atopic dermatitis. J Allergy Clin Immunol 2006 1.02
78 Our evolving understanding of the functional role of filaggrin in atopic dermatitis. J Allergy Clin Immunol 2009 1.02
79 Risk factors of atopic dermatitis patients for eczema herpeticum. J Invest Dermatol 2006 1.02
80 Crystal structure of the streptococcal superantigen SpeI and functional role of a novel loop domain in T cell activation by group V superantigens. J Mol Biol 2007 1.01
81 Racial differences in T-lymphocyte response to glucocorticoids. Chest 2005 1.01
82 Reductions in claudin-1 may enhance susceptibility to herpes simplex virus 1 infections in atopic dermatitis. J Allergy Clin Immunol 2011 1.01
83 Increased glucocorticoid receptor Beta expression converts mouse hybridoma cells to a corticosteroid-insensitive phenotype. Am J Respir Cell Mol Biol 2002 1.00
84 IFN-gamma reverses IL-2- and IL-4-mediated T-cell steroid resistance. Am J Respir Cell Mol Biol 2008 1.00
85 Obesity impairs apoptotic cell clearance in asthma. J Allergy Clin Immunol 2012 0.98
86 The infectious aspects of atopic dermatitis. Immunol Allergy Clin North Am 2010 0.98
87 Adverse consequences of glucocorticoid medication: psychological, cognitive, and behavioral effects. Am J Psychiatry 2014 0.95
88 Advances in atopic dermatitis. Curr Opin Immunol 2011 0.95
89 Characterization of two novel pyrogenic toxin superantigens made by an acute rheumatic fever clone of Streptococcus pyogenes associated with multiple disease outbreaks. Infect Immun 2002 0.94
90 Vaccinia virus-specific molecular signature in atopic dermatitis skin. J Allergy Clin Immunol 2010 0.94
91 Filaggrin-dependent secretion of sphingomyelinase protects against staphylococcal α-toxin-induced keratinocyte death. J Allergy Clin Immunol 2012 0.94
92 Divergent expression and function of glucocorticoid receptor beta in human monocytes and T cells. J Leukoc Biol 2006 0.94
93 Usefulness of PBMCs to predict clinical response to corticosteroids in asthmatic patients. J Allergy Clin Immunol 2012 0.93
94 Serine-arginine-rich protein p30 directs alternative splicing of glucocorticoid receptor pre-mRNA to glucocorticoid receptor beta in neutrophils. J Biol Chem 2003 0.92
95 Decreased IL-15 may contribute to elevated IgE and acute inflammation in atopic dermatitis. J Immunol 2002 0.92
96 Vitamin D enhances glucocorticoid action in human monocytes: involvement of granulocyte-macrophage colony-stimulating factor and mediator complex subunit 14. J Biol Chem 2013 0.91
97 Antiviral activity of human beta-defensin 3 against vaccinia virus. J Allergy Clin Immunol 2007 0.90
98 Advances in allergic skin disease, anaphylaxis, and hypersensitivity reactions to foods, drugs, and insects. J Allergy Clin Immunol 2005 0.90
99 One hundred years of allergen immunotherapy: time to ring the changes. J Allergy Clin Immunol 2011 0.90
100 Actigraphy assessment of sleep disturbance in patients with atopic dermatitis: an objective life quality measure. J Allergy Clin Immunol 2003 0.90
101 Peeling off the layers: skin taping and a novel proteomics approach to study atopic dermatitis. J Allergy Clin Immunol 2009 0.89
102 Inhibition of histone deacetylase 2 expression by elevated glucocorticoid receptor beta in steroid-resistant asthma. Am J Respir Crit Care Med 2010 0.89
103 New era of biologic therapeutics in atopic dermatitis. Expert Opin Biol Ther 2013 0.88
104 Staphylococcus aureus α-toxin modulates skin host response to viral infection. J Allergy Clin Immunol 2012 0.87
105 A multidisciplinary approach to evaluation and treatment of atopic dermatitis. Semin Cutan Med Surg 2008 0.87
106 Severe refractory atopic dermatitis in adults is highly atopic. J Allergy Clin Immunol 2006 0.87
107 Neutrophilic airway inflammation and association with bacterial lipopolysaccharide in children with asthma and wheezing. Pediatr Pulmonol 2008 0.87
108 ATF2 impairs glucocorticoid receptor-mediated transactivation in human CD8+ T cells. Blood 2007 0.87
109 Advances in allergic skin disease, anaphylaxis, and hypersensitivity reactions to foods, drugs, and insects. J Allergy Clin Immunol 2007 0.86
110 Augmentation of staphylococcal alpha-toxin signaling by the epidermal platelet-activating factor receptor. J Invest Dermatol 2003 0.86
111 Advances in allergic skin disease, anaphylaxis, and hypersensitivity reactions to foods, drugs, and insects in 2009. J Allergy Clin Immunol 2010 0.86
112 Advances in allergic skin disease, anaphylaxis, and hypersensitivity reactions to foods, drugs, and insects in 2008. J Allergy Clin Immunol 2009 0.85
113 Specificity protein 1 is pivotal in the skin's antiviral response. J Allergy Clin Immunol 2011 0.85
114 "Black box" warning: wake-up call or overreaction? J Allergy Clin Immunol 2006 0.84
115 Genetic variants in interferon regulatory factor 2 (IRF2) are associated with atopic dermatitis and eczema herpeticum. J Invest Dermatol 2011 0.84
116 Factors that regulate naturally occurring T regulatory cell-mediated suppression. J Allergy Clin Immunol 2005 0.83
117 Advances in allergic skin disease, anaphylaxis, and hypersensitivity reactions to foods, drugs, and insects in 2012. J Allergy Clin Immunol 2012 0.83
118 Microbial superantigens induce glucocorticoid receptor beta and steroid resistance in a nasal explant model. Laryngoscope 2004 0.83
119 Atopic dermatitis: scratching through the complexity of barrier dysfunction. J Allergy Clin Immunol 2013 0.83
120 Inhibition of S100A11 gene expression impairs keratinocyte response against vaccinia virus through downregulation of the IL-10 receptor 2 chain. J Allergy Clin Immunol 2009 0.82
121 Safety of topical calcineurin inhibitors in atopic dermatitis: evaluation of the evidence. Curr Allergy Asthma Rep 2006 0.82
122 Adrenomedullin is highly expressed in blood monocytes associated with acute Kawasaki disease: a microarray gene expression study. Pediatr Res 2004 0.82
123 Advances in allergic skin disease, anaphylaxis, and hypersensitivity reactions to foods, drugs, and insects in 2010. J Allergy Clin Immunol 2010 0.82
124 The ABC's of managing patients with severe atopic dermatitis. J Allergy Clin Immunol 2013 0.82
125 IL-25 enhances HSV-1 replication by inhibiting filaggrin expression, and acts synergistically with Th2 cytokines to enhance HSV-1 replication. J Invest Dermatol 2013 0.81
126 The signal transducer and activator of transcription 6 gene (STAT6) increases the propensity of patients with atopic dermatitis toward disseminated viral skin infections. J Allergy Clin Immunol 2011 0.81
127 Identification of glucocorticoid-induced TNF receptor-related protein ligand on keratinocytes: ligation by GITR induces keratinocyte chemokine production and augments T-cell proliferation. J Invest Dermatol 2009 0.81
128 Advances in allergic skin disease, anaphylaxis, and hypersensitivity reactions to foods, drugs, and insects in 2011. J Allergy Clin Immunol 2012 0.80
129 Sleep disorders in patients with asthma, atopic dermatitis, and allergic rhinitis. J Allergy Clin Immunol 2005 0.79
130 Diet and allergy: you are what you eat? J Allergy Clin Immunol 2005 0.78
131 Immune response to varicella vaccine in children with atopic dermatitis compared with nonatopic controls. J Allergy Clin Immunol 2010 0.78
132 Prospectively assessed early life experiences in relation to cortisol reactivity in adolescents at risk for asthma. Dev Psychobiol 2012 0.78
133 Advances in allergic skin disease, anaphylaxis, and hypersensitivity reactions to foods, drugs, and insects. J Allergy Clin Immunol 2006 0.78
134 Atopic dermatitis. Clin Allergy Immunol 2002 0.78
135 The chemokine receptor CCR6 identifies interferon-gamma expressing T cells and is decreased in atopic dermatitis as compared with psoriasis. J Invest Dermatol 2002 0.78
136 In utero smoke (IUS) exposure has been associated with increased prevalence of asthma and reduced lung function in healthy children. J Allergy Clin Immunol 2010 0.77
137 Advances in atopic dermatitis. Chang Gung Med J 2005 0.77
138 Oral corticosteroids in poorly controlled asthma. J Allergy Clin Immunol 2005 0.77
139 The black box warning for topical calcineurin inhibitors: looking outside the box. Ann Allergy Asthma Immunol 2006 0.77
140 CD56+ cells induce steroid resistance in B cells exposed to IL-15. J Immunol 2004 0.77
141 Inhibition of transcription factor specificity protein 1 alters the gene expression profile of keratinocytes leading to upregulation of kallikrein-related peptidases and thymic stromal lymphopoietin. J Invest Dermatol 2011 0.76
142 Effect of pimecrolimus cream 1% on skin condition and sleep disturbance in children with atopic dermatitis. J Allergy Clin Immunol 2004 0.76
143 Advances in allergic skin disease, anaphylaxis, and hypersensitivity reactions to foods, drugs, and insect stings. J Allergy Clin Immunol 2004 0.76
144 Initiation and maintenance of allergic inflammation: team work at the interface of innate and adaptive immunity. Curr Opin Immunol 2011 0.76
145 Kawasaki syndrome: where are the answers? Pediatrics 2003 0.76
146 Response to "effect of anti-IgE therapy in patients with food allergy". Ann Allergy Asthma Immunol 2003 0.75
147 Progress in peanut allergy research: are we closer to a cure? J Allergy Clin Immunol 2003 0.75
148 Response to cutaneous immunization with low-molecular-weight subunit keyhole limpet hemocyanin. Int Arch Allergy Immunol 2011 0.75
149 Role of microbial toxins in the induction of glucocorticoid receptor beta expression in an explant model of rhinosinusitis. J Otolaryngol 2003 0.75
150 The editors' choice. J Allergy Clin Immunol 2012 0.75
151 Directing the innate immune response to prevent and control allergic diseases. J Allergy Clin Immunol 2008 0.75
152 The Editors' Choice. J Allergy Clin Immunol 2015 0.75
153 Food allergy: are we getting closer to a cure? J Allergy Clin Immunol 2011 0.75
154 Preface to the 2008 mini-primer on allergic and immunologic disease. J Allergy Clin Immunol 2008 0.75
155 Preface to the 2010 primer on allergic and immunologic diseases. J Allergy Clin Immunol 2010 0.75
156 The Editors' Choice. J Allergy Clin Immunol 2015 0.75
157 A familial study of filaggrin mutation in atopic dermatitis. Ann Allergy Asthma Immunol 2013 0.75
158 Preface: the epidermal skin barrier: aspects of biology and dysfunction. J Allergy Clin Immunol 2009 0.75
159 The Editors' Choice. J Allergy Clin Immunol 2015 0.75
160 New series: Perspectives in asthma. J Allergy Clin Immunol 2004 0.75
161 Preface to the 2006 Mini-Primer on Allergic and Immunologic Diseases. J Allergy Clin Immunol 2006 0.75