Novel replication-incompetent vector derived from adenovirus type 11 (Ad11) for vaccination and gene therapy: low seroprevalence and non-cross-reactivity with Ad5.

PubWeight™: 1.53‹?› | Rank: Top 4%

🔗 View Article (PMC 525025)

Published in J Virol on December 01, 2004

Authors

Lennart Holterman1, Ronald Vogels, Remko van der Vlugt, Martijn Sieuwerts, Jos Grimbergen, Jorn Kaspers, Eric Geelen, Esmeralda van der Helm, Angelique Lemckert, Gert Gillissen, Sandra Verhaagh, Jerome Custers, David Zuijdgeest, Ben Berkhout, Margreet Bakker, Paul Quax, Jaap Goudsmit, Menzo Havenga

Author Affiliations

1: Crucell Holland BV, Leiden, The Netherlands.

Articles citing this

Comparative seroprevalence and immunogenicity of six rare serotype recombinant adenovirus vaccine vectors from subgroups B and D. J Virol (2007) 4.54

Immunogenicity of heterologous prime-boost regimens involving recombinant adenovirus serotype 11 (Ad11) and Ad35 vaccine vectors in the presence of anti-ad5 immunity. J Virol (2005) 2.05

Age dependence of adenovirus-specific neutralizing antibody titers in individuals from sub-Saharan Africa. J Clin Microbiol (2006) 1.94

New insights on adenovirus as vaccine vectors. Mol Ther (2009) 1.90

Nasal delivery of an adenovirus-based vaccine bypasses pre-existing immunity to the vaccine carrier and improves the immune response in mice. PLoS One (2008) 1.67

Immunogenicity of recombinant fiber-chimeric adenovirus serotype 35 vector-based vaccines in mice and rhesus monkeys. J Virol (2005) 1.65

Cytotoxic T-lymphocyte escape does not always explain the transient control of simian immunodeficiency virus SIVmac239 viremia in adenovirus-boosted and DNA-primed Mamu-A*01-positive rhesus macaques. J Virol (2005) 1.50

Immunogenicity and protection of a recombinant human adenovirus serotype 35-based malaria vaccine against Plasmodium yoelii in mice. Infect Immun (2006) 1.43

Advances and future challenges in adenoviral vector pharmacology and targeting. Curr Gene Ther (2011) 1.42

Current strategies and future directions for eluding adenoviral vector immunity. Curr Gene Ther (2006) 1.42

Immunogenicity of heterologous recombinant adenovirus prime-boost vaccine regimens is enhanced by circumventing vector cross-reactivity. J Virol (2006) 1.31

Oncolytic Viruses for Cancer Therapy: Overcoming the Obstacles. Viruses (2010) 1.30

Directed evolution generates a novel oncolytic virus for the treatment of colon cancer. PLoS One (2008) 1.30

The influence of innate and pre-existing immunity on adenovirus therapy. J Cell Biochem (2009) 1.25

Development of nonhuman adenoviruses as vaccine vectors. Vaccine (2005) 1.25

Characterization of human adenovirus serotypes 5, 6, 11, and 35 as anticancer agents. Virology (2009) 1.23

The Th1 immune response to Plasmodium falciparum circumsporozoite protein is boosted by adenovirus vectors 35 and 26 with a homologous insert. Clin Vaccine Immunol (2010) 1.17

Adenoviral vector immunity: its implications and circumvention strategies. Curr Gene Ther (2011) 1.07

Cytokine response and survival of mice immunized with an adenovirus expressing Bacillus anthracis protective antigen domain 4. Infect Immun (2006) 1.06

Production of adenovirus vectors and their use as a delivery system for influenza vaccines. Expert Opin Biol Ther (2010) 1.01

Human immunodeficiency virus type 1 vaccine development: recent advances in the cytotoxic T-lymphocyte platform "spotty business". J Virol (2007) 0.96

Adenoviruses use lactoferrin as a bridge for CAR-independent binding to and infection of epithelial cells. J Virol (2006) 0.94

Transposon-assisted cloning and traceless mutagenesis of adenoviruses: Development of a novel vector based on species D. J Virol (2006) 0.93

Applying genomic and bioinformatic resources to human adenovirus genomes for use in vaccine development and for applications in vector development for gene delivery. Viruses (2010) 0.92

The influence of delivery vectors on HIV vaccine efficacy. Front Microbiol (2014) 0.92

Advances and future challenges in recombinant adenoviral vectored H5N1 influenza vaccines. Viruses (2012) 0.89

Adenoviral producer cells. Viruses (2010) 0.82

Barriers to systemic application of virus-based vectors in gene therapy: lessons from adenovirus type 5. Virus Genes (2017) 0.82

Transduction and oncolytic profile of a potent replication-competent adenovirus 11p vector (RCAd11pGFP) in colon carcinoma cells. PLoS One (2011) 0.81

Getting genetic access to natural adenovirus genomes to explore vector diversity. Virus Genes (2017) 0.81

Low seroprevalent species D adenovirus vectors as influenza vaccines. PLoS One (2013) 0.81

Pancreatic cancer gene therapy: from molecular targets to delivery systems. Cancers (Basel) (2011) 0.81

Progress on adenovirus-vectored universal influenza vaccines. Hum Vaccin Immunother (2015) 0.80

Oncolytic Group B Adenovirus Enadenotucirev Mediates Non-apoptotic Cell Death with Membrane Disruption and Release of Inflammatory Mediators. Mol Ther Oncolytics (2016) 0.79

Circumventing antivector immunity: potential use of nonhuman adenoviral vectors. Hum Gene Ther (2014) 0.79

Modification of the early gene enhancer-promoter improves the oncolytic potency of adenovirus 11. Mol Ther (2011) 0.79

Selective transduction of mature DC in human skin and lymph nodes by CD80/CD86-targeted fiber-modified adenovirus-5/3. J Immunother (2009) 0.78

Adenovirus Vector-Derived VA-RNA-Mediated Innate Immune Responses. Pharmaceutics (2011) 0.76

Changing faces in virology: the dutch shift from oncogenic to oncolytic viruses. Hum Gene Ther (2014) 0.75

Phase 1 study of intravenous administration of the chimeric adenovirus enadenotucirev in patients undergoing primary tumor resection. J Immunother Cancer (2017) 0.75

Articles cited by this

Replication-incompetent adenoviral vaccine vector elicits effective anti-immunodeficiency-virus immunity. Nature (2002) 12.49

Development of a preventive vaccine for Ebola virus infection in primates. Nature (2000) 8.32

Accelerated vaccination for Ebola virus haemorrhagic fever in non-human primates. Nature (2003) 6.35

Replication-deficient human adenovirus type 35 vectors for gene transfer and vaccination: efficient human cell infection and bypass of preexisting adenovirus immunity. J Virol (2003) 4.48

Comparative immunogenicity in rhesus monkeys of DNA plasmid, recombinant vaccinia virus, and replication-defective adenovirus vectors expressing a human immunodeficiency virus type 1 gag gene. J Virol (2003) 4.41

Administration of an adenovirus containing the human CFTR cDNA to the respiratory tract of individuals with cystic fibrosis. Nat Genet (1994) 4.40

CD46 is a cellular receptor for group B adenoviruses. Nat Med (2003) 4.35

A controlled study of adenoviral-vector-mediated gene transfer in the nasal epithelium of patients with cystic fibrosis. N Engl J Med (1995) 4.30

Membrane cofactor protein (MCP or CD46): newest member of the regulators of complement activation gene cluster. Annu Rev Immunol (1991) 4.27

Adenoviruses in the immunocompromised host. Clin Microbiol Rev (1992) 3.56

Quantifying adenovirus-neutralizing antibodies by luciferase transgene detection: addressing preexisting immunity to vaccine and gene therapy vectors. J Clin Microbiol (2003) 3.29

Overcoming immunity to a viral vaccine by DNA priming before vector boosting. J Virol (2003) 2.67

Adenovirus type 11 uses CD46 as a cellular receptor. J Virol (2003) 2.52

New helper cells and matched early region 1-deleted adenovirus vectors prevent generation of replication-competent adenoviruses. Hum Gene Ther (1998) 2.37

Novel, chimpanzee serotype 68-based adenoviral vaccine carrier for induction of antibodies to a transgene product. J Virol (2002) 2.31

The human membrane cofactor CD46 is a receptor for species B adenovirus serotype 3. J Virol (2004) 2.11

Canine adenovirus vectors: an alternative for adenovirus-mediated gene transfer. J Virol (2000) 2.00

Neutralizing antibodies and CD8+ T lymphocytes both contribute to immunity to adenovirus serotype 5 vaccine vectors. J Virol (2004) 1.86

Membrane cofactor protein of the complement system: alternative splicing of serine/threonine/proline-rich exons and cytoplasmic tails produces multiple isoforms that correlate with protein phenotype. J Exp Med (1991) 1.68

Plasmid chemokines and colony-stimulating factors enhance the immunogenicity of DNA priming-viral vector boosting human immunodeficiency virus type 1 vaccines. J Virol (2003) 1.60

The interactions of peptides with the innate immune system studied with use of T7 phage peptide display. Mol Ther (2000) 1.58

Improved adenovirus vectors for infection of cardiovascular tissues. J Virol (2001) 1.55

Impact of preexisting and induced humoral and cellular immune responses in an adenovirus-based gene therapy phase I clinical trial for localized mesothelioma. Hum Gene Ther (1998) 1.51

Analytical anion-exchange HPLC of recombinant type-5 adenoviral particles. Hum Gene Ther (1997) 1.50

Beta-galactosidase gene transfer to human malignant glioma in vivo using replication-deficient retroviruses and adenoviruses. Hum Gene Ther (1998) 1.46

Ovine adenovirus vectors overcome preexisting humoral immunity against human adenoviruses in vivo. J Virol (1999) 1.40

Phase I trial of recombinant adenovirus gene transfer in lung cancer. Longitudinal study of the immune responses to transgene and viral products. J Clin Invest (1997) 1.39

Development of adenovirus serotype 35 as a gene transfer vector. Virology (2003) 1.33

Poly (lactic-glycolic) acid copolymer encapsulation of recombinant adenovirus reduces immunogenicity in vivo. Gene Ther (1998) 1.19

Human membrane cofactor protein (MCP, CD46): multiple isoforms and functions. Int J Biochem Cell Biol (1999) 1.16

Cartilage degradation and invasion by rheumatoid synovial fibroblasts is inhibited by gene transfer of TIMP-1 and TIMP-3. Gene Ther (2003) 1.14

Adenovirus complexed with polyethylene glycol and cationic lipid is shielded from neutralizing antibodies in vitro. Gene Ther (1998) 1.05

Gene therapy for cardiovascular diseases. Curr Pharm Des (2004) 0.99

Comparative analysis of the genome organization of human adenovirus 11, a member of the human adenovirus species B, and the commonly used human adenovirus 5 vector, a member of species C. J Gen Virol (2003) 0.98

Gene delivery of vaccines for infectious disease. Curr Opin Mol Ther (2001) 0.98

Binding of human urokinase-type plasminogen activator to its receptor: residues involved in species specificity and binding. Arterioscler Thromb Vasc Biol (1998) 0.96

The complete nucleotide sequence, genome organization, and origin of human adenovirus type 11. Virology (2003) 0.94

Adenoviral expression of a urokinase receptor-targeted protease inhibitor inhibits neointima formation in murine and human blood vessels. Circulation (2001) 0.90

The migration of human smooth muscle cells in vitro is mediated by plasminogen activation and can be inhibited by alpha2-macroglobulin receptor associated protein. Thromb Haemost (1997) 0.89

A recombinant E1-deleted porcine adenovirus-3 as an expression vector. Virology (2003) 0.88

Genetically modified viruses: vaccines by design. Curr Pharm Biotechnol (2001) 0.88

Priming of T cells with Ad-transduced DC followed by expansion with peptide-pulsed DC significantly enhances the induction of tumor-specific CD8+ T cells: implications for an efficient vaccination strategy. Gene Ther (2003) 0.87

Articles by these authors

Antibody recognition of a highly conserved influenza virus epitope. Science (2009) 11.26

Identification of a new human coronavirus. Nat Med (2004) 11.24

Heterosubtypic neutralizing monoclonal antibodies cross-protective against H5N1 and H1N1 recovered from human IgM+ memory B cells. PLoS One (2008) 6.98

Immune control of an SIV challenge by a T-cell-based vaccine in rhesus monkeys. Nature (2008) 6.17

A highly conserved neutralizing epitope on group 2 influenza A viruses. Science (2011) 5.66

Towards an HIV cure: a global scientific strategy. Nat Rev Immunol (2012) 5.52

Vaccine protection against acquisition of neutralization-resistant SIV challenges in rhesus monkeys. Nature (2012) 5.49

Adenovirus serotype 5 hexon mediates liver gene transfer. Cell (2008) 5.00

Hexon-chimaeric adenovirus serotype 5 vectors circumvent pre-existing anti-vector immunity. Nature (2006) 4.59

Comparative seroprevalence and immunogenicity of six rare serotype recombinant adenovirus vaccine vectors from subgroups B and D. J Virol (2007) 4.54

Replication-deficient human adenovirus type 35 vectors for gene transfer and vaccination: efficient human cell infection and bypass of preexisting adenovirus immunity. J Virol (2003) 4.48

Immunogenicity of recombinant adenovirus serotype 35 vaccine in the presence of pre-existing anti-Ad5 immunity. J Immunol (2004) 4.36

Stabilization of the soluble, cleaved, trimeric form of the envelope glycoprotein complex of human immunodeficiency virus type 1. J Virol (2002) 3.59

Highly conserved protective epitopes on influenza B viruses. Science (2012) 3.47

Quantifying adenovirus-neutralizing antibodies by luciferase transgene detection: addressing preexisting immunity to vaccine and gene therapy vectors. J Clin Microbiol (2003) 3.29

Human immunodeficiency virus type 1 escapes from RNA interference-mediated inhibition. J Virol (2004) 3.23

HIV-1 can escape from RNA interference by evolving an alternative structure in its RNA genome. Nucleic Acids Res (2005) 2.93

Neutralizing antibodies to adenovirus serotype 5 vaccine vectors are directed primarily against the adenovirus hexon protein. J Immunol (2005) 2.84

Magnitude and phenotype of cellular immune responses elicited by recombinant adenovirus vectors and heterologous prime-boost regimens in rhesus monkeys. J Virol (2008) 2.66

Immune protection of nonhuman primates against Ebola virus with single low-dose adenovirus vectors encoding modified GPs. PLoS Med (2006) 2.64

Identification of coagulation factor (F)X binding sites on the adenovirus serotype 5 hexon: effect of mutagenesis on FX interactions and gene transfer. Blood (2009) 2.55

Adenovirus types 5 and 35 seroprevalence in AIDS risk groups supports type 35 as a vaccine vector. AIDS (2004) 2.51

Silencing of HIV-1 with RNA interference: a multiple shRNA approach. Mol Ther (2006) 2.48

The Ebola virus VP35 protein is a suppressor of RNA silencing. PLoS Pathog (2007) 2.48

Trafficking of antigen-specific CD8+ T lymphocytes to mucosal surfaces following intramuscular vaccination. J Immunol (2008) 2.35

Suppression of RNA interference by adenovirus virus-associated RNA. J Virol (2005) 2.29

A novel pancoronavirus RT-PCR assay: frequent detection of human coronavirus NL63 in children hospitalized with respiratory tract infections in Belgium. BMC Infect Dis (2005) 2.28

Human coronavirus NL63 employs the severe acute respiratory syndrome coronavirus receptor for cellular entry. Proc Natl Acad Sci U S A (2005) 2.21

Towards an RTS,S-based, multi-stage, multi-antigen vaccine against falciparum malaria: progress at the Walter Reed Army Institute of Research. Vaccine (2005) 2.18

Lentiviral vector design for multiple shRNA expression and durable HIV-1 inhibition. Mol Ther (2008) 2.14

RNA interference against viruses: strike and counterstrike. Nat Biotechnol (2007) 2.14

Adenovirus-specific immunity after immunization with an Ad5 HIV-1 vaccine candidate in humans. Nat Med (2009) 2.10

Viral evolution as a tool to improve the tetracycline-regulated gene expression system. J Biol Chem (2004) 2.06

Immunogenicity of heterologous prime-boost regimens involving recombinant adenovirus serotype 11 (Ad11) and Ad35 vaccine vectors in the presence of anti-ad5 immunity. J Virol (2005) 2.05

In HIV-1 pathogenesis the die is cast during primary infection. AIDS (2007) 2.04

The novel tuberculosis vaccine, AERAS-402, induces robust and polyfunctional CD4+ and CD8+ T cells in adults. Am J Respir Crit Care Med (2010) 2.03

Croup is associated with the novel coronavirus NL63. PLoS Med (2005) 2.03

Detection of new viruses by VIDISCA. Virus discovery based on cDNA-amplified fragment length polymorphism. Methods Mol Biol (2008) 1.95

Age dependence of adenovirus-specific neutralizing antibody titers in individuals from sub-Saharan Africa. J Clin Microbiol (2006) 1.94

Isolation and characterization of human monoclonal antibodies from individuals infected with West Nile Virus. J Virol (2006) 1.91

International seroepidemiology of adenovirus serotypes 5, 26, 35, and 48 in pediatric and adult populations. Vaccine (2011) 1.88

First-in-human evaluation of the safety and immunogenicity of a recombinant adenovirus serotype 26 HIV-1 Env vaccine (IPCAVD 001). J Infect Dis (2012) 1.87

Neutralizing antibodies and CD8+ T lymphocytes both contribute to immunity to adenovirus serotype 5 vaccine vectors. J Virol (2004) 1.86

Protective immune responses to a recombinant adenovirus type 35 tuberculosis vaccine in two mouse strains: CD4 and CD8 T-cell epitope mapping and role of gamma interferon. Infect Immun (2007) 1.85

Retroviral superinfection resistance. Retrovirology (2005) 1.82

A novel long distance base-pairing interaction in human immunodeficiency virus type 1 RNA occludes the Gag start codon. J Biol Chem (2002) 1.81

Differential transmission of human immunodeficiency virus type 1 by distinct subsets of effector dendritic cells. J Virol (2002) 1.78

Priming with an adenovirus 35-circumsporozoite protein (CS) vaccine followed by RTS,S/AS01B boosting significantly improves immunogenicity to Plasmodium falciparum CS compared to that with either malaria vaccine alone. Infect Immun (2007) 1.75

Synergistic activation of human immunodeficiency virus type 1 promoter activity by NF-kappaB and inhibitors of deacetylases: potential perspectives for the development of therapeutic strategies. J Virol (2002) 1.75

The leader of human immunodeficiency virus type 1 genomic RNA harbors an internal ribosome entry segment that is active during the G2/M phase of the cell cycle. J Virol (2003) 1.71

Human monoclonal antibody as prophylaxis for SARS coronavirus infection in ferrets. Lancet (2004) 1.70

Inhibition of virus replication by RNA interference. J Biomed Sci (2003) 1.70

Immunogenicity of recombinant fiber-chimeric adenovirus serotype 35 vector-based vaccines in mice and rhesus monkeys. J Virol (2005) 1.65

Inhibition of HIV-1 by multiple siRNAs expressed from a single microRNA polycistron. Nucleic Acids Res (2008) 1.65

Human monoclonal antibodies against West Nile virus induced by natural infection neutralize at a postattachment step. J Virol (2009) 1.65

Factor correction as a tool to eliminate between-session variation in replicate experiments: application to molecular biology and retrovirology. Retrovirology (2006) 1.64

Emergence of a drug-dependent human immunodeficiency virus type 1 variant during therapy with the T20 fusion inhibitor. J Virol (2004) 1.64

Highly sensitive methods based on seminested real-time reverse transcription-PCR for quantitation of human immunodeficiency virus type 1 unspliced and multiply spliced RNA and proviral DNA. J Clin Microbiol (2008) 1.61

New class of monoclonal antibodies against severe influenza: prophylactic and therapeutic efficacy in ferrets. PLoS One (2010) 1.59

The novel human coronaviruses NL63 and HKU1. J Virol (2006) 1.59

Identification of sequential viral escape mutants associated with altered T-cell responses in a human immunodeficiency virus type 1-infected individual. J Virol (2003) 1.57

Neutralization of West Nile virus by cross-linking of its surface proteins with Fab fragments of the human monoclonal antibody CR4354. Proc Natl Acad Sci U S A (2010) 1.57

Major decline of hepatitis C virus incidence rate over two decades in a cohort of drug users. Eur J Epidemiol (2007) 1.52

Multiple secondary structure rearrangements during HIV-1 RNA dimerization. Biochemistry (2002) 1.50

Human immunodeficiency virus type 1 escape is restricted when conserved genome sequences are targeted by RNA interference. J Virol (2007) 1.50

Microprocessor, Setx, Xrn2, and Rrp6 co-operate to induce premature termination of transcription by RNAPII. Cell (2012) 1.49

Myeloid and plasmacytoid dendritic cells are susceptible to recombinant adenovirus vectors and stimulate polyfunctional memory T cell responses. J Immunol (2007) 1.44

The tRNA primer activation signal in the human immunodeficiency virus type 1 genome is important for initiation and processive elongation of reverse transcription. J Virol (2002) 1.40

Mosaic structure of human coronavirus NL63, one thousand years of evolution. J Mol Biol (2006) 1.40

Proteomic studies reveal coordinated changes in T-cell expression patterns upon infection with human immunodeficiency virus type 1. J Virol (2008) 1.40

Genome structure and transcriptional regulation of human coronavirus NL63. Virol J (2004) 1.39

Cell-associated HIV RNA: a dynamic biomarker of viral persistence. Retrovirology (2013) 1.37

Human coronavirus NL63, a new respiratory virus. FEMS Microbiol Rev (2006) 1.37