Published in Circulation on November 15, 2004
Arterial calcification in chronic kidney disease: key roles for calcium and phosphate. Circ Res (2011) 2.56
Inflammatory macrophage migration requires MMP-9 activation by plasminogen in mice. J Clin Invest (2008) 2.16
Modification of the effect of glycemic status on aortic distensibility by age in the multi-ethnic study of atherosclerosis. Hypertension (2009) 1.69
Reactive oxygen species, inflammation and calcium oxalate nephrolithiasis. Transl Androl Urol (2014) 1.64
Novel aspects of the pathogenesis of aneurysms of the abdominal aorta in humans. Cardiovasc Res (2010) 1.33
Osteogenic responses in fibroblasts activated by elastin degradation products and transforming growth factor-beta1: role of myofibroblasts in vascular calcification. Am J Pathol (2007) 1.16
Elastin degradation and vascular smooth muscle cell phenotype change precede cell loss and arterial medial calcification in a uremic mouse model of chronic kidney disease. Am J Pathol (2011) 1.14
The mechanism of vascular calcification - a systematic review. Med Sci Monit (2012) 1.13
Elastin calcification in the rat subdermal model is accompanied by up-regulation of degradative and osteogenic cellular responses. Am J Pathol (2006) 1.03
Unified theory on the pathogenesis of Randall's plaques and plugs. Urolithiasis (2014) 1.02
Spatiotemporal expression and localization of matrix metalloproteinas-9 in a murine model of thoracic aortic aneurysm. J Vasc Surg (2006) 1.01
Alterations in aortic cellular constituents during thoracic aortic aneurysm development: myofibroblast-mediated vascular remodeling. Am J Pathol (2009) 0.98
Clinical, cellular, and molecular aspects of arterial calcification. J Vasc Surg (2007) 0.96
Role of inflammation in the pathogenesis of heart failure with preserved ejection fraction and its potential as a therapeutic target. Heart Fail Rev (2014) 0.95
Matrix metalloproteinases promote arterial remodeling in aging, hypertension, and atherosclerosis. Hypertension (2015) 0.94
Alteration of vaginal elastin metabolism in women with pelvic organ prolapse. Obstet Gynecol (2010) 0.94
Phosphate and vascular calcification: Emerging role of the sodium-dependent phosphate co-transporter PiT-1. Thromb Haemost (2010) 0.94
Catalase overexpression in aortic smooth muscle prevents pathological mechanical changes underlying abdominal aortic aneurysm formation. Am J Physiol Heart Circ Physiol (2011) 0.93
Cardiomyopathy is associated with structural remodelling of heart valve extracellular matrix. Eur Heart J (2009) 0.92
Increased bone resorption is associated with increased risk of cardiovascular events in men: the MINOS study. J Bone Miner Res (2009) 0.92
Transglutaminase 2-mediated activation of β-catenin signaling has a critical role in warfarin-induced vascular calcification. Arterioscler Thromb Vasc Biol (2011) 0.91
Development of a novel rabbit model of abdominal aortic aneurysm via a combination of periaortic calcium chloride and elastase incubation. PLoS One (2013) 0.90
Arterial calcification is driven by RAGE in Enpp1-/- mice. J Vasc Res (2010) 0.89
Induced elastin regeneration by chronically activated smooth muscle cells for targeted aneurysm repair. Acta Biomater (2009) 0.88
Activation of arterial matrix metalloproteinases leads to vascular calcification in chronic kidney disease. Am J Nephrol (2011) 0.88
The increased expression of matrix metalloproteinases associated with elastin degradation and fibrosis of the ligamentum flavum in patients with lumbar spinal stenosis. Clin Orthop Surg (2009) 0.87
Alterations in membrane type-1 matrix metalloproteinase abundance after the induction of thoracic aortic aneurysm in a murine model. Am J Physiol Heart Circ Physiol (2010) 0.86
Vascular protective role of vitexicarpin isolated from Vitex rotundifolia in human umbilical vein endothelial cells. Inflammation (2012) 0.85
Utility of hyaluronan oligomers and transforming growth factor-beta1 factors for elastic matrix regeneration by aneurysmal rat aortic smooth muscle cells. Tissue Eng Part A (2009) 0.85
Markers of increased cardiovascular risk in patients with chronic kidney disease. Lipids Health Dis (2014) 0.84
Inflammation in cardiovascular tissue engineering: the challenge to a promise: a minireview. Int J Inflam (2011) 0.84
Mitigation of diabetes-related complications in implanted collagen and elastin scaffolds using matrix-binding polyphenol. Biomaterials (2012) 0.83
Modeling brain dynamics using computational neurogenetic approach. Cogn Neurodyn (2008) 0.83
Development of a novel murine model of aortic aneurysms using peri-adventitial elastase. Surgery (2012) 0.81
Hydroxyapatite and calcified elastin induce osteoblast-like differentiation in rat aortic smooth muscle cells. Exp Cell Res (2014) 0.81
Evaluating smooth muscle cells from CaCl2-induced rat aortal expansions as a surrogate culture model for study of elastogenic induction of human aneurysmal cells. Tissue Eng Part A (2011) 0.81
Chemokine (C-C motif) receptor 2 mediates mast cell migration to abdominal aortic aneurysm lesions in mice. Cardiovasc Res (2012) 0.81
Nanoparticle targeting to diseased vasculature for imaging and therapy. Nanomedicine (2014) 0.81
Combining two potential causes of metalloproteinase secretion causes abdominal aortic aneurysms in rats: a new experimental model. Int J Exp Pathol (2010) 0.80
Micro-CT evaluation of high pressure-decellularized cardiovascular tissues transplanted in rat subcutaneous accelerated-calcification model. J Artif Organs (2014) 0.79
MMP-9- and NMDA receptor-mediated mechanism of diabetic renovascular remodeling and kidney dysfunction: hydrogen sulfide is a key modulator. Nitric Oxide (2015) 0.79
Efficacy of reversal of aortic calcification by chelating agents. Calcif Tissue Int (2013) 0.79
GNAS haploinsufficiency leads to subcutaneous tumor formation with collagen and elastin deposition and calcification. Endocr Res (2009) 0.78
Targeted chelation therapy with EDTA-loaded albumin nanoparticles regresses arterial calcification without causing systemic side effects. J Control Release (2014) 0.78
TWEAK favors phosphate-induced calcification of vascular smooth muscle cells through canonical and non-canonical activation of NFκB. Cell Death Dis (2016) 0.78
Molecular Mechanisms of Arterial Stiffening. Pulse (Basel) (2016) 0.77
Breast arterial calcification is associated with reproductive factors in asymptomatic postmenopausal women. J Womens Health (Larchmt) (2010) 0.77
Clinical and histopathological characteristics of a family with R1141X mutation of pseudoxanthoma elasticum - presymptomatic testing and lack of carrier phenotypes. Int J Dermatol (2013) 0.77
Carotid calcification in mice: a new model to study the effects of arterial stiffness on the brain. J Am Heart Assoc (2013) 0.76
The Involvement of miR-29b-3p in Arterial Calcification by Targeting Matrix Metalloproteinase-2. Biomed Res Int (2017) 0.75
The crosstalk between vascular MSCs and inflammatory mediators determines the pro-calcific remodelling of human atherosclerotic aneurysm. Stem Cell Res Ther (2017) 0.75
Macrophage glucocorticoid receptors join the intercellular dialogue in atherosclerotic lesion calcification. Arterioscler Thromb Vasc Biol (2008) 0.75
Inhibition of MAPK-Erk pathway in vivo attenuates aortic valve disease processes in Emilin1-deficient mouse model. Physiol Rep (2017) 0.75
Insights from molecular modeling into the selective inhibition of cathepsin S by its inhibitor. J Mol Model (2017) 0.75
Matrix metalloproteinases 2 and 9 work in concert to produce aortic aneurysms. J Clin Invest (2002) 4.79
Inflammation and matrix metalloproteinases in the enlarging abdominal aortic aneurysm. Arterioscler Thromb Vasc Biol (1995) 3.00
Targetting of the gene encoding fibrillin-1 recapitulates the vascular aspect of Marfan syndrome. Nat Genet (1997) 2.98
Medial localization of mineralization-regulating proteins in association with Mönckeberg's sclerosis: evidence for smooth muscle cell-mediated vascular calcification. Circulation (1999) 2.95
Phenotypic alteration of vascular smooth muscle cells precedes elastolysis in a mouse model of Marfan syndrome. Circ Res (2001) 2.22
Murine aortic aneurysm produced by periarterial application of calcium chloride. J Surg Res (2001) 1.37
Aneurysm of the rabbit common carotid artery induced by periarterial application of calcium chloride in vivo. J Clin Invest (1988) 1.27
A murine model of thoracic aortic aneurysms. J Surg Res (2003) 1.16
Recent advances in multifactorial regulation of vascular calcification. Curr Opin Lipidol (2001) 1.15
Aluminum interaction with plasma membrane lipids and enzyme metal binding sites and its potential role in Al cytotoxicity. FEBS Lett (1997) 1.15
Biology of calcification in vascular cells: intima versus media. Herz (2001) 1.14
Inhibition of matrix metalloproteinase activity attenuates tenascin-C production and calcification of implanted purified elastin in rats. Am J Pathol (2000) 1.13
Mönckeberg's medial sclerosis and inorganic phosphate in uremia. Am J Kidney Dis (2001) 1.07
Determination of the elastin content of tissues by measuring desmosine and isodesmosine. Anal Biochem (1977) 1.06
Elastin calcification and its prevention with aluminum chloride pretreatment. Am J Pathol (1999) 1.03
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Role of elastin in pathologic calcification of xenograft heart valves. J Biomed Mater Res A (2003) 0.97
Influence of hypercholesterolemia and adventitial inflammation on the development of aortic aneurysm in rabbits. Arterioscler Thromb Vasc Biol (1997) 0.96
Elastin in blood vessels. Ciba Found Symp (1995) 0.93
Application of nanoparticle technology for the prevention of restenosis after balloon injury in rats. Circ Res (2003) 0.93
Arterial calcifications: morphological aspects and their pathological implications. Z Kardiol (2001) 0.89
Aluminum chloride pretreatment of elastin inhibits elastolysis by matrix metalloproteinases and leads to inhibition of elastin-oriented calcification. Am J Pathol (2001) 0.89
Activation of metalloproteinase-2, loss of matrix scleroprotein content and coronary artery calcification. Atherosclerosis (2001) 0.86
Provocation of experimental aortic inflammation and dilatation by inflammatory mediators and Chlamydia pneumoniae. Br J Surg (2001) 0.83
Chlamydia pneumoniae antigens facilitate experimental aortic dilatation: prevention with azithromycin. J Vasc Surg (2002) 0.81
Matrix metalloproteinases 2 and 9 work in concert to produce aortic aneurysms. J Clin Invest (2002) 4.79
Fibulin-5 is an elastin-binding protein essential for elastic fibre development in vivo. Nature (2002) 3.60
Mast cells modulate the pathogenesis of elastase-induced abdominal aortic aneurysms in mice. J Clin Invest (2007) 2.00
Targeted disruption of fibulin-4 abolishes elastogenesis and causes perinatal lethality in mice. Mol Cell Biol (2006) 1.97
Quantitative and comparative studies of the vocal fold extracellular matrix. I: Elastic fibers and hyaluronic acid. Ann Otol Rhinol Laryngol (2006) 1.74
Key roles of CD4+ T cells and IFN-gamma in the development of abdominal aortic aneurysms in a murine model. J Immunol (2004) 1.72
Inhibiting lung elastase activity enables lung growth in mechanically ventilated newborn mice. Am J Respir Crit Care Med (2011) 1.67
Doxycycline in patients with abdominal aortic aneurysms and in mice: comparison of serum levels and effect on aneurysm growth in mice. J Vasc Surg (2002) 1.57
Recombinant human elastin polypeptides self-assemble into biomaterials with elastin-like properties. Biopolymers (2003) 1.50
Doxycycline delays aneurysm rupture in a mouse model of Marfan syndrome. J Vasc Surg (2008) 1.48
MMP-12 has a role in abdominal aortic aneurysms in mice. Surgery (2005) 1.35
Novel porous aortic elastin and collagen scaffolds for tissue engineering. Biomaterials (2004) 1.24
Enhancing mechanical properties of tissue-engineered constructs via lysyl oxidase crosslinking activity. J Biomed Mater Res A (2003) 1.23
Elastin stabilization for treatment of abdominal aortic aneurysms. Circulation (2007) 1.22
Stability and function of glycosaminoglycans in porcine bioprosthetic heart valves. Biomaterials (2005) 1.21
Blocking TNF-alpha attenuates aneurysm formation in a murine model. J Immunol (2009) 1.20
Structural requirements for stabilization of vascular elastin by polyphenolic tannins. Biomaterials (2006) 1.17
Membrane-type 1 matrix metalloproteinase regulates macrophage-dependent elastolytic activity and aneurysm formation in vivo. J Biol Chem (2008) 1.17
Osteogenic responses in fibroblasts activated by elastin degradation products and transforming growth factor-beta1: role of myofibroblasts in vascular calcification. Am J Pathol (2007) 1.16
Inhibition of reactive oxygen species attenuates aneurysm formation in a murine model. Atherosclerosis (2008) 1.15
Fabrication of cardiac patch with decellularized porcine myocardial scaffold and bone marrow mononuclear cells. J Biomed Mater Res A (2010) 1.15
Molecular analysis of fibulin-5 function during de novo synthesis of elastic fibers. Mol Cell Biol (2006) 1.13
Multiple Chlamydia pneumoniae antigens prime CD8+ Tc1 responses that inhibit intracellular growth of this vacuolar pathogen. J Immunol (2002) 1.11
Temporal patterns of postoperative complications. Arch Surg (2003) 1.11
Inhibition of microRNA-29 enhances elastin levels in cells haploinsufficient for elastin and in bioengineered vessels--brief report. Arterioscler Thromb Vasc Biol (2011) 1.11
Deletion of CCR2 but not CCR5 or CXCR3 inhibits aortic aneurysm formation. Surgery (2007) 1.08
MMP-2 regulates Erk1/2 phosphorylation and aortic dilatation in Marfan syndrome. Circ Res (2012) 1.08
Elastin stabilization in cardiovascular implants: improved resistance to enzymatic degradation by treatment with tannic acid. Biomaterials (2004) 1.07
Chronically ischemic mouse skeletal muscle exhibits myopathy in association with mitochondrial dysfunction and oxidative damage. Am J Physiol Regul Integr Comp Physiol (2008) 1.07
Localized administration of doxycycline suppresses aortic dilatation in an experimental mouse model of abdominal aortic aneurysm. Ann Vasc Surg (2006) 1.06
Distribution of the elastic fiber and associated proteins in flexor tendon reflects function. Anat Rec (2002) 1.06
Vitamin C prevents the effects of prenatal nicotine on pulmonary function in newborn monkeys. Am J Respir Crit Care Med (2005) 1.06
Degeneration of bioprosthetic heart valve cusp and wall tissues is initiated during tissue preparation: an ultrastructural study. J Heart Valve Dis (2003) 1.05
Tannic acid treatment enhances biostability and reduces calcification of glutaraldehyde fixed aortic wall. Biomaterials (2005) 1.03
Elastin calcification in the rat subdermal model is accompanied by up-regulation of degradative and osteogenic cellular responses. Am J Pathol (2006) 1.03
Glycosaminoglycan-degrading enzymes in porcine aortic heart valves: implications for bioprosthetic heart valve degeneration. J Heart Valve Dis (2003) 1.02
Distinct steps of cross-linking, self-association, and maturation of tropoelastin are necessary for elastic fiber formation. J Mol Biol (2007) 1.02
Chronic lung disease in preterm lambs: effect of daily vitamin A treatment on alveolarization. Am J Physiol Lung Cell Mol Physiol (2010) 1.02
Mechanism of inhibition of matrix metalloproteinase-2 expression by doxycycline in human aortic smooth muscle cells. J Vasc Surg (2003) 1.01
Assembly and testing of stem cell-seeded layered collagen constructs for heart valve tissue engineering. Tissue Eng Part A (2010) 0.99
Mechanisms of emphysema in autosomal dominant cutis laxa. Matrix Biol (2010) 0.99
Population differences in elastin maturation in optic nerve head tissue and astrocytes. Invest Ophthalmol Vis Sci (2007) 0.98
MOP3, a component of the molecular clock, regulates the development of B cells. Immunology (2006) 0.98
Construction of high-density bacterial colony arrays and patterns by the ink-jet method. Biotechnol Bioeng (2004) 0.97
Development of a new in vitro model of elastic fiber assembly in human pigmented epithelial cells. Clin Biochem (2005) 0.97
Effects of tissue inhibitor of metalloproteinase 2 deficiency on aneurysm formation. J Vasc Surg (2006) 0.96
Stabilized collagen scaffolds for heart valve tissue engineering. Tissue Eng Part A (2009) 0.95
MT1-MMP regulates the PI3Kδ·Mi-2/NuRD-dependent control of macrophage immune function. Genes Dev (2012) 0.94
Neonatal mice genetically modified to express the elastase inhibitor elafin are protected against the adverse effects of mechanical ventilation on lung growth. Am J Physiol Lung Cell Mol Physiol (2012) 0.94
Neomycin prevents enzyme-mediated glycosaminoglycan degradation in bioprosthetic heart valves. Biomaterials (2007) 0.93
PPARgamma deficiency results in reduced lung elastic recoil and abnormalities in airspace distribution. Respir Res (2010) 0.93
Regulation of alveolar epithelial cell apoptosis and pulmonary fibrosis by coordinate expression of components of the fibrinolytic system. Am J Physiol Lung Cell Mol Physiol (2011) 0.92
Glycosaminoglycan-targeted fixation for improved bioprosthetic heart valve stabilization. Biomaterials (2006) 0.90
Oxidative and nitrosative modifications of tropoelastin prevent elastic fiber assembly in vitro. J Biol Chem (2010) 0.90
Extracellular matrix degrading enzymes are active in porcine stentless aortic bioprosthetic heart valves. J Biomed Mater Res A (2003) 0.90
Design and Testing of a Pulsatile Conditioning System for Dynamic Endothelialization of Polyphenol-Stabilized Tissue Engineered Heart Valves. Cardiovasc Eng Technol (2010) 0.89
A CD8+ T cell heptaepitope minigene vaccine induces protective immunity against Chlamydia pneumoniae. J Immunol (2005) 0.89
DANCE/fibulin-5 promotes elastic fiber formation in a tropoelastin isoform-dependent manner. Clin Biochem (2009) 0.89
Domains 16 and 17 of tropoelastin in elastic fibre formation. Biochem J (2007) 0.89
Toward cell therapy for vascular calcification: osteoclast-mediated demineralization of calcified elastin. Cardiovasc Pathol (2007) 0.89
MMP-9 microsatellite polymorphism and susceptibility to carotid arteries atherosclerosis. Arterioscler Thromb Vasc Biol (2006) 0.88
Macrophage differentiation and polarization on a decellularized pericardial biomaterial. Biomaterials (2010) 0.88
In vivo cellular repopulation of tubular elastin scaffolds mediated by basic fibroblast growth factor. Biomaterials (2007) 0.87
Impaired alveolar development and abnormal lung elastin in preterm lambs with chronic lung injury: potential benefits of retinol treatment. Biol Neonate (2003) 0.86
Polyphenol-stabilized tubular elastin scaffolds for tissue engineered vascular grafts. Tissue Eng Part A (2009) 0.85
Novel tissue-derived biomimetic scaffold for regenerating the human nucleus pulposus. J Biomed Mater Res A (2010) 0.85
Inflammation in cardiovascular tissue engineering: the challenge to a promise: a minireview. Int J Inflam (2011) 0.84
Structural and biomechanical characterizations of porcine myocardial extracellular matrix. J Mater Sci Mater Med (2012) 0.84
Dose-related influence of chronic alcohol consumption on cerebral ischemia/reperfusion injury. Alcohol Clin Exp Res (2011) 0.83
Pharmacological approaches to prevent abdominal aortic aneurysm enlargement and rupture. Ann N Y Acad Sci (2006) 0.83
Elevation of plasma high-density lipoproteins inhibits development of experimental abdominal aortic aneurysms. Arterioscler Thromb Vasc Biol (2012) 0.83
Regenerative potential of decellularized porcine nucleus pulposus hydrogel scaffolds: stem cell differentiation, matrix remodeling, and biocompatibility studies. Tissue Eng Part A (2013) 0.83
Mitigation of diabetes-related complications in implanted collagen and elastin scaffolds using matrix-binding polyphenol. Biomaterials (2012) 0.83
The acellular myocardial flap: a novel extracellular matrix scaffold enriched with patent microvascular networks and biocompatible cell niches. Tissue Eng Part C Methods (2013) 0.82
The characteristics of elastic fiber assembled with recombinant tropoelastin isoform. Clin Biochem (2006) 0.82
Janus magnetic cellular spheroids for vascular tissue engineering. Biomaterials (2013) 0.82
Neomycin binding preserves extracellular matrix in bioprosthetic heart valves during in vitro cyclic fatigue and storage. Acta Biomater (2008) 0.81
Engineered zinc-finger proteins can compensate genetic haploinsufficiency by transcriptional activation of the wild-type allele: application to Willams-Beuren syndrome and supravalvular aortic stenosis. Hum Gene Ther (2012) 0.81
Genetic dissection of hyperthermia-induced neural tube defects in mice. Birth Defects Res A Clin Mol Teratol (2003) 0.81
Vascular management in rotationplasty. Clin Orthop Relat Res (2008) 0.79
Platform technologies for decellularization, tunic-specific cell seeding, and in vitro conditioning of extended length, small diameter vascular grafts. Tissue Eng Part C Methods (2014) 0.79
Construction of tissue-engineered small-diameter vascular grafts in fibrin scaffolds in 30 days. Tissue Eng Part A (2014) 0.79
MMP-2 genetic variant and plaque features of instability. Atherosclerosis (2010) 0.79