John A Kemp

Author PubWeight™ 16.97^‹?›

Top papers

Rank	Title	Journal	Year	PubWeight™‹?›
1	Ionotropic and metabotropic glutamate receptor structure and pharmacology.	Psychopharmacology (Berl)	2005	2.25
2	Human C-reactive protein increases cerebral infarct size after middle cerebral artery occlusion in adult rats.	J Cereb Blood Flow Metab	2004	1.21
3	Pharmacological manipulation of mGlu2 receptors influences cognitive performance in the rodent.	Neuropharmacology	2004	1.17
4	The voltage-dependent anion channel is the target for a new class of inhibitors of the mitochondrial permeability transition pore.	J Biol Chem	2003	1.15
5	Severe impairment of NMDA receptor function in mice carrying targeted point mutations in the glycine binding site results in drug-resistant nonhabituating hyperactivity.	J Neurosci	2002	1.14
6	PS2APP transgenic mice, coexpressing hPS2mut and hAPPswe, show age-related cognitive deficits associated with discrete brain amyloid deposition and inflammation.	J Neurosci	2003	1.08
7	Role of caspase-3 activation in cerebral ischemia-induced neurodegeneration in adult and neonatal brain.	J Cereb Blood Flow Metab	2002	1.06
8	Glutamate- and GABA-based CNS therapeutics.	Curr Opin Pharmacol	2005	1.00
9	Identification of critical residues in the amino terminal domain of the human NR2B subunit involved in the RO 25-6981 binding pocket.	J Pharmacol Exp Ther	2003	0.95
10	Antiparkinsonian activity of Ro 25-6981, a NR2B subunit specific NMDA receptor antagonist, in animal models of Parkinson's disease.	Exp Neurol	2004	0.95
11	Evidence for improved performance in cognitive tasks following selective NR2B NMDA receptor antagonist pre-treatment in the rat.	Psychopharmacology (Berl)	2005	0.91
12	Differential regulation of synaptic transmission by mGlu2 and mGlu3 at the perforant path inputs to the dentate gyrus and CA1 revealed in mGlu2 -/- mice.	Neuropharmacology	2002	0.89
13	Identification and characterization of a novel splice variant of the metabotropic glutamate receptor 5 gene in human hippocampus and cerebellum.	Brain Res Mol Brain Res	2002	0.88
14	Early-onset and robust amyloid pathology in a new homozygous mouse model of Alzheimer's disease.	PLoS One	2009	0.88
15	Pharmacological and genetic evidence indicates that combined inhibition of NR2A and NR2B subunit containing NMDA receptors is required to disrupt prepulse inhibition.	Psychopharmacology (Berl)	2004	0.85
16	Asymmetric synthesis and receptor pharmacology of the group II mGlu receptor ligand (1S,2R,3R,5R,6S)-2-amino-3-hydroxy-bicyclo[3.1.0]hexane-2,6-dicarboxylic acid-HYDIA.	ChemMedChem	2008	0.76