I Morishima

Author PubWeight™ 73.78‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Stepwise formation of alpha-helices during cytochrome c folding. Nat Struct Biol 2000 2.02
2 Roles of proximal ligand in heme proteins: replacement of proximal histidine of human myoglobin with cysteine and tyrosine by site-directed mutagenesis as models for P-450, chloroperoxidase, and catalase. Biochemistry 1993 1.29
3 Roles of the axial push effect in cytochrome P450cam studied with the site-directed mutagenesis at the heme proximal site. J Inorg Biochem 2000 1.03
4 Intra- and intermolecular beta-pleated sheet formation in glutamine-repeat inserted myoglobin as a model for polyglutamine diseases. J Biol Chem 2001 1.02
5 Proximal cysteine residue is essential for the enzymatic activities of cytochrome P450cam. Eur J Biochem 2001 1.01
6 Minimum structure of peptidoglycan required for induction of antibacterial protein synthesis in the silkworm, Bombyx mori. Insect Biochem Mol Biol 1999 0.98
7 Cerebral oxygen utilization analyzed by the use of oxygen-17 and its nuclear magnetic resonance. Biochem Biophys Res Commun 1990 0.97
8 The effects of heme pocket hydrophobicity on the ligand binding dynamics in myoglobin as studied with leucine 29 mutants. J Biol Chem 1997 0.93
9 Identification of histidine 77 as the axial heme ligand of carbonmonoxy CooA by picosecond time-resolved resonance Raman spectroscopy. Biochemistry 2000 0.93
10 Structure and ligand binding properties of leucine 29(B10) mutants of human myoglobin. J Biol Chem 1992 0.92
11 Heme environmental structure of CooA is modulated by the target DNA binding. Evidence from resonance Raman spectroscopy and CO rebinding kinetics. J Biol Chem 1998 0.91
12 On the mechanism of the chemical and enzymic oxygenations of alpha-oxyprotohemin IX to Fe.biliverdin IX alpha. Proc Natl Acad Sci U S A 1986 0.91
13 Presence of endogenous calcium ion and its functional and structural regulation in horseradish peroxidase. J Biol Chem 1986 0.90
14 Binding of CO at the Pro2 side is crucial for the activation of CO-sensing transcriptional activator CooA. (1)H NMR spectroscopic studies. J Biol Chem 2001 0.89
15 Catalytic activities and structural properties of horseradish peroxidase distal His42 --> Glu or Gln mutant. Biochemistry 1997 0.88
16 Site-directed mutagenesis in hemoglobin: functional and structural role of inter- and intrasubunit hydrogen bonds as studied with 37 beta and 145 beta mutations. Biochemistry 1992 0.88
17 Mutagenesis and the molecular modeling of the rat angiotensin II receptor (AT1). J Biol Chem 1995 0.87
18 Nuclear magnetic resonance studies in hemoproteins. IX. pH dependent features of horse heart ferric cytochrome c. Biochim Biophys Acta 1977 0.87
19 Protein purification, cDNA cloning and gene expression of lysozyme from eri-silkworm, Samia cynthia ricini. Comp Biochem Physiol B Biochem Mol Biol 2001 0.87
20 Detection of a tryptophan radical as an intermediate species in the reaction of horseradish peroxidase mutant (Phe-221 --> Trp) and hydrogen peroxide. J Biol Chem 1998 0.86
21 High-pressure proton nuclear magnetic resonance studies of hemoproteins. Pressure-induced structural change in heme environments of myoglobin, hemoglobin, and horseradish peroxidase. Biochemistry 1980 0.86
22 Proton nuclear magnetic resonance spectra of compounds I and II of horseradish peroxidase. Biochemistry 1978 0.86
23 Protective effects of carvedilol against doxorubicin-induced cardiomyopathy in rats. Life Sci 1999 0.86
24 Structural roles of the highly conserved glu residue in the heme distal site of peroxidases. Biochemistry 1998 0.85
25 Site-directed mutagenesis in haemoglobin. Functional role of tyrosine-42(C7) alpha at the alpha 1-beta 2 interface. J Mol Biol 1991 0.85
26 Disulfide bridges in extracellular domains of angiotensin II receptor type IA. Regul Pept 1995 0.85
27 Isothermal titration calorimetric studies on the associations of putidaredoxin to NADH-putidaredoxin reductase and P450cam. Biochim Biophys Acta 1998 0.85
28 Alteration of human myoglobin proximal histidine to cysteine or tyrosine by site-directed mutagenesis: characterization and their catalytic activities. Biochem Biophys Res Commun 1991 0.85
29 cAMP-induced changes of intracellular free Mg2+ levels in human erythrocytes. Biochim Biophys Acta 1993 0.84
30 Preparation and reactions of myoglobin mutants bearing both proximal cysteine ligand and hydrophobic distal cavity: protein models for the active site of P-450. Biochemistry 1996 0.84
31 Ligand migration in human myoglobin: steric effects of isoleucine 107(G8) on O(2) and CO binding. Biophys J 2001 0.84
32 Melatonin scavenges hydroxyl radical and protects isolated rat hearts from ischemic reperfusion injury. Life Sci 2000 0.84
33 Catalytic roles of the distal site asparagine-histidine couple in peroxidases. Biochemistry 1996 0.83
34 The role of water molecules in the association of cytochrome P450cam with putidaredoxin. An osmotic pressure study. J Biol Chem 2001 0.83
35 Nuclear magnetic resonance studies of hemoproteins. Binding of aromatic donor molecules to horseradish peroxidase. J Biol Chem 1979 0.83
36 Single-crystal EPR study of novel azide complex of cyanogen bromide-modified myoglobin. Influence of specific modification of the heme distal histidyl residue on the ligand-binding structure. J Biol Chem 1989 0.83
37 High-pressure laser photolysis study of hemoproteins. Effects of pressure on carbon monoxide binding dynamics for R- and T-state hemoglobins. Biochemistry 1990 0.83
38 NMR studies of putidaredoxin: associations of putidaredoxin with NADH-putidaredoxin reductase and cytochrome p450cam. Biochim Biophys Acta 1998 0.82
39 Loss and restoration of sensitivity to epinephrine in cultured BHK cells: effect of inhibitors of RNA and protein synthesis. Mol Pharmacol 1980 0.82
40 Study of the specific heme orientation in reconstituted hemoglobins. Biochemistry 1988 0.82
41 High-pressure nuclear magnetic resonance studies of hemoproteins. Pressure-induced structural changes in the heme environments of ferric low-spin metmyoglobin complexes. Biochemistry 1983 0.81
42 Proton NMR study of hemoproteins. Ionization and orientation of iron-bound imidazole in methemoglobin and metmyoblobin. Biochim Biophys Acta 1980 0.81
43 Cloning of cDNAs for cecropins A and B, and expression of the genes in the silkworm, Bombyx mori. Biosci Biotechnol Biochem 1994 0.81
44 The effects of pressure on oxygen and carbon monoxide binding kinetics for myoglobin. A high pressure laser flash photolysis study. J Biol Chem 1989 0.81
45 Hydrogen bond network in the distal site of peroxidases: spectroscopic properties of Asn70 --> Asp horseradish peroxidase mutant. Biochemistry 1997 0.81
46 Site-directed mutagenesis in hemoglobin: functional and structural study of the intersubunit hydrogen bond of threonine-38(C3)alpha at the alpha 1-beta 2 interface in human hemoglobin. Biochemistry 1993 0.81
47 The electronic and vibrational structures of iron-oxo porphyrin with a methoxide or cysteinate axial ligand. J Inorg Biochem 2000 0.80
48 Nuclear magnetic resonance studies of hemoproteins. Acid-alkaline transition, ligand binding characteristics, and structure of the heme environments in horseradish peroxidase. Biochemistry 1977 0.80
49 Presence of endogenous calcium ion in horseradish peroxidase. Elucidation of metal-binding site by substitutions of divalent and lanthanide ions for calcium and use of metal-induced NMR (1H and 113Cd) resonances. J Biol Chem 1986 0.80
50 The artificial alpha1beta1-contact mutant hemoglobin, Hb Phe-35beta, shows only small functional abnormalities. FEBS Lett 1998 0.80
51 Calcium binding by horseradish peroxidase C and the heme environmental structure. Biochem Biophys Res Commun 1979 0.79
52 Roles of negatively charged surface residues of putidaredoxin in interactions with redox partners in p450cam monooxygenase system. Biochim Biophys Acta 1998 0.79
53 Transition state of an unfolding step in human cyanomet myoglobin. Biochim Biophys Acta 1993 0.79
54 Site-directed mutagenesis in hemoglobin: functional and structural role of the penultimate tyrosine in the alpha subunit. Biochemistry 1994 0.79
55 Simultaneous quantitation of ceramides and 1,2-diacylglycerol in tissues by Iatroscan thin-layer chromatography-flame-ionization detection. Lipids 1998 0.79
56 Unusual pressure effects on ligand rebinding to the human myoglobin Leucine 29 mutants. J Biol Chem 2000 0.78
57 'Module'-substituted globins: artificial exon shuffling among myoglobin, hemoglobin alpha- and beta-subunits. Biophys Chem 1997 0.78
58 NMR study of human mutant hemoglobins synthesized in Escherichia coli. Consequences of tyrosine alpha 42 substitutions. J Biol Chem 1989 0.78
59 NMR study of hybrid hemoglobins containing unnatural heme: effect of heme modification on their tertiary and quaternary structures. Biochemistry 1986 0.78
60 Effects of intra- and intersubunit hydrogen bonds on the R-T transition in human hemoglobin as studied with alpha 42(C7) and beta 145(HC2) mutations. Biochemistry 1993 0.78
61 Cyclic nucleotide phosphodiesterase in silkworm: purification and properties. Biochim Biophys Acta 1974 0.78
62 Electron transfer reactions in Zn-substituted cytochrome P450cam. Biochemistry 2000 0.78
63 Structural characterization of lactoperoxidase in the heme environment by proton NMR spectroscopy. Biochemistry 1986 0.78
64 Nuclear magnetic resonance studies of hemoproteins. IV. Hindered rotation of heme side methyl group as a probe for studying van der Waals contacts in the heme side environments of myoglobin derivatives. Biochim Biophys Acta 1975 0.77
65 Binding of imidazoles to manganese (III) protoporphyrin in water. Biochemistry 1981 0.77
66 Structural and functional roles of heme binding module in globin proteins: identification of the segment regulating the heme binding structure. J Mol Biol 1998 0.77
67 NMR studies of hemoproteins. VI. Acid-base transitions of ferric myoglobin and its imidazole complex. Biochim Biophys Acta 1975 0.77
68 Effects of the intramolecular disulfide bond on ligand binding dynamics in myoglobin. Biochemistry 1997 0.77
69 Crystal structure of a protein with an artificial exon-shuffling, module M4-substituted chimera hemoglobin beta alpha, at 2.5 A resolution. J Mol Biol 1999 0.77
70 A novel spermatogenesis-related factor-1 gene expressed in maturing rat testis. Biochem Biophys Res Commun 2001 0.77
71 "Module" substitution in hemoglobin subunits. Preparation and characterization of a "chimera beta alpha-subunit". J Biol Chem 1994 0.77
72 Structure of genes for cecropin A and an inducible nuclear protein that binds to the promoter region of the genes from the silkworm, Bombyx mori. Biosci Biotechnol Biochem 1998 0.77
73 Induction of antibacterial protein synthesis by soluble peptidoglycan in isolated fat body from larvae of the silkworm, Bombyx mori. Insect Biochem Mol Biol 1993 0.76
74 Proton nuclear magnetic resonance studies of compounds I and II of horseradish peroxidase. Biochem Biophys Res Commun 1978 0.76
75 High-pressure flash photolysis study of hemoprotein: effects of substrate analogues on the recombination of carbon monoxide to cytochrome P450CAM. Biochemistry 1994 0.76
76 220 MHz proton NMR studies of hemoproteins. High-spin-low-spin equilibrium in ferric myoglobin and hemoglobin derivatives. Biochim Biophys Acta 1974 0.76
77 Substitution of the heme binding module in hemoglobin alpha- and beta-subunits. Implication for different regulation mechanisms of the heme proximal structure between hemoglobin and myoglobin. J Biol Chem 2000 0.76
78 Luminol activity of horseradish peroxidase mutants mimicking a proposed binding site for luminol in Arthromyces ramosus peroxidase. Biochemistry 1999 0.76
79 Time-resolved hole-burning study on myoglobin: fluctuation of restricted water within distal pocket. Biophys J 2001 0.76
80 Cylic nucleotide phosphodiesterase in silkworm. Characterization of cyclic GMP phosphodiesterase. Biochim Biophys Acta 1975 0.76
81 Putative hydrogen bond network in the heme distal site of horseradish peroxidase. Biochem Biophys Res Commun 1995 0.76
82 The distal glutamic acid as an acid-base catalyst in the distal site of horseradish peroxidase. Biochem Biophys Res Commun 1996 0.76
83 Proton magnetic resonance studies of specific association of nucleic acid constitutent bases in a nonaqueous solvent. Utility of DTBN radical to probe the affinity of hydrogen bonding involved in complementary base pairs1. J Am Chem Soc 1977 0.76
84 Interaction of fully liganded valency hybrid hemoglobin with inositol hexaphosphate. Implication of the IHP-induced T state of human adult methemoglobin in the low-spin state. Biochemistry 1986 0.76
85 Pressure overload per se rather than cardiac angiotensin converting enzyme activity may be important in the development of rat cardiac hypertrophy. J Hypertens 1997 0.75
86 Pressure effects on carbon monoxide rebinding to the isolated alpha and beta chains of human hemoglobin. Biochemistry 1991 0.75
87 Functions of fluctuation in the heme-binding loops of cytochrome b5 revealed in the process of heme incorporation. Biochemistry 2000 0.75
88 Effects of magnesium sulfate on an unfolding step of human cyanomet myoglobin. Biophys J 1993 0.75
89 Proton magnetic resonance spectra of tRNA-Met-f from Thermus thermophilus. Nucleic Acids Res 1977 0.75
90 Nuclear magnetic resonance studies of hemoproteins. Unusual temperature dependence of hyperfine shifts and spin equilibrium in ferric myoglobin and hemoglobin derivatives. J Am Chem Soc 1974 0.75
91 High pressure NMR studies of hemoproteins. The effect of pressure on the quaternary structure of hemoglobin. Biochem Biophys Res Commun 1984 0.75
92 Proton magnetic resonance study of p-mercuribenzoate binding and structural changes in methemoglobin. Biochemistry 1980 0.75
93 Purification and properties of sugar-non-specific nuclease in pupa of silkworm, Bombyx mori Linné. Biochim Biophys Acta 1968 0.75
94 Relationship between the apolipoprotein E and angiotensin-converting enzyme genotypes and LDL particle size in Japanese subjects. Clin Chim Acta 1999 0.75
95 Modification of the heme distal side in myoglobin by cyanogen bromide. Heme environmental structures and ligand binding properties of the modified myoglobin. Biochemistry 1984 0.75
96 Effects of roxithromycin on proliferation of peripheral blood mononuclear cells and production of lipopolysaccharide-induced cytokines. Biol Pharm Bull 1995 0.75
97 NMR studies of recombinant cytochrome P450cam mutants. Biochimie 1996 0.75
98 The experimental study on the intra-articular fibrinogenolysis in hemarthrosis. Nagoya Med J 1968 0.75
99 Design, construction, crystallization, and preliminary X-ray studies of a fine-tuning mutant (F133V) of module-substituted chimera hemoglobin. Proteins 1998 0.75
100 Interaction of methemoglobin with inositol hexaphosphate. Presence of the T state in human adult methemoglobin in the low spin state. J Biol Chem 1981 0.75
101 Inhibition of guanylate cyclase by guanosine 3'-phosphate and 2'-deoxyguanosine 3'-phosphate in silkworm fat body. J Biochem 1982 0.75
102 Interaction of human adult methemoglobin in low-spin state with inositol hexaphosphate. A proton magnetic resonance study. Biochem Biophys Res Commun 1980 0.75
103 Proximal strain and visible absorption changes in the model complexes of imidazole methemoglobin. J Biol Chem 1981 0.75
104 Decreased intracellular free magnesium in erythrocytes of spontaneously hypertensive rats. Biochem Biophys Res Commun 1987 0.75
105 Letter: Nuclear magnetic resonance studies of hemoproteins. Restricted rotation of a heme side chain methyl group in some ferric myoglobin complexes and its implication in van der Waals contact in the heme side chain environments. J Am Chem Soc 1974 0.75
106 Modification of the distal histidyl imidazole in myoglobin to N-tetrazole-substituted imidazole and its effects on the heme environmental structure and ligand binding properties. Biochemistry 1992 0.75
107 Structural and functional roles of modules in hemoglobin. Substitution of module M4 in hemoglobin subunits. J Biol Chem 1997 0.75
108 Nuclear magnetic resonance studies of hemoproteins. Interaction of horseradish peroxidase with indolepropionic acid. FEBS Lett 1977 0.75
109 Proton nuclear magnetic resonance study of formate binding to metmyoglobin. FEBS Lett 1977 0.75
110 Molecular orbital interpretations for cholinergic activities of some alkyltrialkylammonium derivatives. Chem Pharm Bull (Tokyo) 1974 0.75
111 Low density lipoprotein particle size is associated with glycosylated hemoglobin levels regardless of plasma lipid levels. Intern Med 1998 0.75
112 15N magnetic resonance studies of the binding of 15N-labeled cyanide to various hemoproteins. Biochem Biophys Res Commun 1977 0.75
113 Structural and functional effects of pseudo-module substitution in hemoglobin subunits. New structural and functional units in globin structure. J Biol Chem 1998 0.75
114 Cyclic nucleotide phosphodiesterase in silkworm. Developmental change of cyclic AMP and cyclic GMP phosphodiesterases. Biochim Biophys Acta 1975 0.75
115 Studies on DNA synthesis in silkworm pupae infected with nuclear polyhedrosis virus. J Biochem 1968 0.75
116 Adenylate cyclase in silkworm. Properties of the enzyme in pupal fat body. J Biochem 1978 0.75
117 Kinetic studies of spin interconversion in ferric mixed-spin derivatives of myoglobin. Biopolymers 1981 0.75
118 Modulation of LDL particle size after an oral glucose load is associated with insulin levels. Clin Chim Acta 1998 0.75
119 Nuclear magnetic resonance studies of hemoprotein. Proton hyperfine shifts and structural characterization of the different heme environments in methemoglobin and metmyoglobin. Biochim Biophys Acta 1978 0.75
120 Cyclic nucleotide phosphodiesterase in silkworm. Separation and characterization of multiple forms of the enzyme. Biochim Biophys Acta 1975 0.75
121 Unusually fast ligand exchange rate in horseradish peroxidase as studied by temperature-jump method. Biochem Biophys Res Commun 1978 0.75
122 15N NMR studies of the binding of 15N-labeled cyanide to various hemoglobins in intact erythrocyte. Biochem Biophys Res Commun 1978 0.75
123 Reaction of horseradish peroxidase with azide and some implications for the heme environmental structure. NMR and kinetic studies. Biochim Biophys Acta 1978 0.75
124 NMR studies of hemoproteins: pH dependence of ferric horseradish peroxidase and horse heart myoglobin. FEBS Lett 1976 0.75
125 NMR studies of the binding of 15N-labeled ligands to hemoproteins. pH-Dependent features of heme-bound C15N-resonances in cyanide complexes of myoglobin and cytochrome c and some implications for their heme environmental structures. FEBS Lett 1977 0.75
126 Ruthenium-iron hybrid hemoglobins as a model for partially liganded hemoglobin: oxygen equilibrium curves and resonance Raman spectra. Biochemistry 1989 0.75
127 Nuclear magnetic resonance studies of hemoproteins. VIII. Proton NMR studies of the binding of various nitrogenous ligands to ferric cytochrome c. Biochim Biophys Acta 1978 0.75
128 Ruthenium-iron hybrid hemoglobins as a model for partially liganded hemoglobin: NMR studies of their tertiary and quaternary structures. Biochemistry 1988 0.75
129 High pressure NMR studies of hemoproteins. The effect of pressure on the tertiary and quaternary structures of human adult ferrous hemoglobin. J Biol Chem 1983 0.75
130 Studies of ternary complexes of adrenaline, adenine nucleotide and metal ion by proton magnetic resonance spectroscopy, and its pharmacological significance with respect to the adrenergic mechanism. I. Chem Biol Interact 1971 0.75
131 Proton NMR study of methemoglobin and its isolated chains. Effect of the subunit association on the structure of the subunits. J Biol Chem 1979 0.75
132 Adenylate cyclase in silkworm. Effects of adenosine 3'-phosphate and 2'-deoxyadenosine 3'-phosphate on the enzyme system in fat body. Biochim Biophys Acta 1980 0.75
133 [Clinical diagnosis of early breast cancer]. Gan To Kagaku Ryoho 1994 0.75