Published in Pharm Res on October 01, 2004
Clinical relevance of the ESKAPE pathogens. Expert Rev Anti Infect Ther (2013) 2.24
Design, optimization and characterisation of polymeric microneedle arrays prepared by a novel laser-based micromoulding technique. Pharm Res (2010) 1.76
Microneedle-mediated intradermal delivery of 5-aminolevulinic acid: potential for enhanced topical photodynamic therapy. J Control Release (2008) 1.65
Skin dendritic cell targeting via microneedle arrays laden with antigen-encapsulated poly-D,L-lactide-co-glycolide nanoparticles induces efficient antitumor and antiviral immune responses. ACS Nano (2013) 1.58
Staphylococcus epidermidis device-related infections: pathogenesis and clinical management. J Pharm Pharmacol (2008) 1.58
Long-term, controlled release of the HIV microbicide TMC120 from silicone elastomer vaginal rings. J Antimicrob Chemother (2005) 1.48
Microneedle-based drug delivery systems: microfabrication, drug delivery, and safety. Drug Deliv (2010) 1.46
Optical coherence tomography is a valuable tool in the study of the effects of microneedle geometry on skin penetration characteristics and in-skin dissolution. J Control Release (2010) 1.42
Hydrogel-Forming Microneedle Arrays for Enhanced Transdermal Drug Delivery. Adv Funct Mater (2012) 1.32
Recent advances in bacteriophage therapy: how delivery routes, formulation, concentration and timing influence the success of phage therapy. J Pharm Pharmacol (2011) 1.27
Laser-engineered dissolving microneedle arrays for transdermal macromolecular drug delivery. Pharm Res (2011) 1.21
Microneedles for intradermal and transdermal drug delivery. Eur J Pharm Sci (2013) 1.18
Influence of array interspacing on the force required for successful microneedle skin penetration: theoretical and practical approaches. J Pharm Sci (2013) 1.17
Microneedle arrays allow lower microbial penetration than hypodermic needles in vitro. Pharm Res (2009) 1.14
Processing difficulties and instability of carbohydrate microneedle arrays. Drug Dev Ind Pharm (2009) 1.13
Development and evaluation of a vaginal ring device for sustained delivery of HIV microbicides to non-human primates. J Med Primatol (2009) 1.11
Effects of microneedle length, density, insertion time and multiple applications on human skin barrier function: assessments by transepidermal water loss. Toxicol In Vitro (2010) 1.10
Mucoadhesive drug delivery systems. J Pharm Bioallied Sci (2011) 1.07
Mucosal allergic sensitization to cockroach allergens is dependent on proteinase activity and proteinase-activated receptor-2 activation. J Immunol (2011) 1.07
Multihospital outbreak of Clostridium difficile ribotype 027 infection: epidemiology and analysis of control measures. Infect Control Hosp Epidemiol (2011) 1.06
Non-aqueous silicone elastomer gels as a vaginal microbicide delivery system for the HIV-1 entry inhibitor maraviroc. J Control Release (2011) 1.05
Vaginal delivery of the recombinant HIV-1 clade-C trimeric gp140 envelope protein CN54gp140 within novel rheologically structured vehicles elicits specific immune responses. Vaccine (2009) 1.03
Hydrogel-forming microneedle arrays can be effectively inserted in skin by self-application: a pilot study centred on pharmacist intervention and a patient information leaflet. Pharm Res (2014) 1.02
Microneedle-mediated intradermal nanoparticle delivery: Potential for enhanced local administration of hydrophobic pre-formed photosensitisers. Photodiagnosis Photodyn Ther (2010) 1.01
Antimicrobial activity of short, synthetic cationic lipopeptides. Chem Biol Drug Des (2010) 1.01
Characterization of the rheological, mucoadhesive, and drug release properties of highly structured gel platforms for intravaginal drug delivery. Biomacromolecules (2009) 1.00
The potential of antimicrobial peptides as biocides. Int J Mol Sci (2011) 0.99
Anti-adherent and antifungal activities of surfactant-coated poly(ethylcyanoacrylate) nanoparticles. Int J Pharm (2007) 0.98
Sustained release of proteins from a modified vaginal ring device. Eur J Pharm Biopharm (2010) 0.96
Influence of skin model on in vitro performance of drug-loaded soluble microneedle arrays. Int J Pharm (2012) 0.96
Novel inhibitors of the Pseudomonas aeruginosa virulence factor LasB: a potential therapeutic approach for the attenuation of virulence mechanisms in pseudomonal infection. Antimicrob Agents Chemother (2011) 0.96
Dissolving polymeric microneedle arrays for electrically assisted transdermal drug delivery. J Control Release (2012) 0.96
Serum CA19.9 levels are commonly elevated in primary ovarian mucinous tumours but cannot be used to predict the histological subtype. J Clin Pathol (2010) 0.95
Biomolecular mechanisms of staphylococcal biofilm formation. Future Microbiol (2013) 0.95
Drug delivery strategies for photodynamic antimicrobial chemotherapy: from benchtop to clinical practice. J Photochem Photobiol B (2009) 0.95
Gene delivery using dimethyldidodecylammonium bromide-coated PLGA nanoparticles. Biomaterials (2010) 0.94
Microneedle-mediated vaccine delivery: harnessing cutaneous immunobiology to improve efficacy. Expert Opin Drug Deliv (2012) 0.94
Gentamicin-loaded nanoparticles show improved antimicrobial effects towards Pseudomonas aeruginosa infection. Int J Nanomedicine (2012) 0.93
Eradication of Pseudomonas aeruginosa biofilms by atmospheric pressure non-thermal plasma. PLoS One (2012) 0.93
Germline MSH6 mutations are more prevalent in endometrial cancer patient cohorts than hereditary non polyposis colorectal cancer cohorts. Ulster Med J (2008) 0.93
Physical characterisation and component release of poly(vinyl alcohol)-tetrahydroxyborate hydrogels and their applicability as potential topical drug delivery systems. Int J Pharm (2011) 0.93
Celecoxib-loaded poly(D,L-lactide-co-glycolide) nanoparticles prepared using a novel and controllable combination of diffusion and emulsification steps as part of the salting-out procedure. J Microencapsul (2006) 0.93
Microporation techniques for enhanced delivery of therapeutic agents. Recent Pat Drug Deliv Formul (2010) 0.91
Photosensitiser delivery for photodynamic therapy. Part 2: systemic carrier platforms. Expert Opin Drug Deliv (2008) 0.91
The use of lytic bacteriophages in the prevention and eradication of biofilms of Proteus mirabilis and Escherichia coli. FEMS Immunol Med Microbiol (2010) 0.91
Designing photosensitizers for photodynamic therapy: strategies, challenges and promising developments. Future Med Chem (2009) 0.91
Hydrogel-forming and dissolving microneedles for enhanced delivery of photosensitizers and precursors. Photochem Photobiol (2013) 0.91
Review of patents on microneedle applicators. Recent Pat Drug Deliv Formul (2011) 0.90
Intravaginal immunization using the recombinant HIV-1 clade-C trimeric envelope glycoprotein CN54gp140 formulated within lyophilized solid dosage forms. Vaccine (2011) 0.90
Radical excision of vulval disease and multidisciplinary tissue flap reconstruction: the belfast experience. Int J Gynecol Cancer (2012) 0.89
Hydrogel-forming microneedle arrays exhibit antimicrobial properties: potential for enhanced patient safety. Int J Pharm (2013) 0.89
Investigation of solute permeation across hydrogels composed of poly(methyl vinyl ether-co-maleic acid) and poly(ethylene glycol). J Pharm Pharmacol (2010) 0.88
ZapA, a virulence factor in a rat model of Proteus mirabilis-induced acute and chronic prostatitis. Infect Immun (2008) 0.88
Electrically enhanced solute permeation across poly(ethylene glycol)-crosslinked poly(methyl vinyl ether-co-maleic acid) hydrogels: effect of hydrogel crosslink density and ionic conductivity. Int J Pharm (2011) 0.88
Synergistic phage-antibiotic combinations for the control of Escherichia coli biofilms in vitro. FEMS Immunol Med Microbiol (2012) 0.88
The role of microneedles for drug and vaccine delivery. Expert Opin Drug Deliv (2014) 0.87
Microneedle arrays as medical devices for enhanced transdermal drug delivery. Expert Rev Med Devices (2011) 0.87
Electrical methods of controlling bacterial adhesion and biofilm on device surfaces. Expert Rev Med Devices (2013) 0.87
Laser-engineered dissolving microneedles for active transdermal delivery of nadroparin calcium. Eur J Pharm Biopharm (2012) 0.87
Development of novel oral formulations prepared via hot melt extrusion for targeted delivery of photosensitizer to the colon. Photochem Photobiol (2011) 0.86
Application of atmospheric pressure nonthermal plasma for the in vitro eradication of bacterial biofilms. FEMS Immunol Med Microbiol (2012) 0.86
Photodynamic Antimicrobial Chemotherapy (PACT) in combination with antibiotics for treatment of Burkholderia cepacia complex infection. J Photochem Photobiol B (2011) 0.85
Controlled-release vaginal ring drug-delivery systems: a key strategy for the development of effective HIV microbicides. Ther Deliv (2010) 0.85
Microneedle mediated intradermal delivery of adjuvanted recombinant HIV-1 CN54gp140 effectively primes mucosal boost inoculations. J Control Release (2012) 0.85
Immunocolloidal targeting of the endocytotic siglec-7 receptor using peripheral attachment of siglec-7 antibodies to poly(lactide-co-glycolide) nanoparticles. Pharm Res (2007) 0.85
Effect of sub-lethal challenge with Photodynamic Antimicrobial Chemotherapy (PACT) on the antibiotic susceptibility of clinical bacterial isolates. J Photochem Photobiol B (2010) 0.85
Microneedle characterisation: the need for universal acceptance criteria and GMP specifications when moving towards commercialisation. Drug Deliv Transl Res (2015) 0.85
Bioadhesive patch-based delivery of 5-aminolevulinic acid to the nail for photodynamic therapy of onychomycosis. J Control Release (2005) 0.85
Enhanced antitumor activity of the photosensitizer meso-Tetra(N-methyl-4-pyridyl) porphine tetra tosylate through encapsulation in antibody-targeted chitosan/alginate nanoparticles. Biomacromolecules (2013) 0.84
Drug delivery of aminolevulinic acid from topical formulations intended for photodynamic therapy. Photochem Photobiol (2005) 0.84
Enhanced surface attachment of protein-type targeting ligands to poly(lactide-co-glycolide) nanoparticles using variable expression of polymeric acid functionality. J Biomed Mater Res A (2008) 0.84
Novel patch-based systems for the localised delivery of ALA-esters. J Photochem Photobiol B (2010) 0.84
Strategies for the development of the urinary catheter. Expert Rev Med Devices (2007) 0.84
An examination of the rheological and mucoadhesive properties of poly(acrylic acid) organogels designed as platforms for local drug delivery to the oral cavity. J Pharm Sci (2007) 0.83
Laser-engineered dissolving microneedle arrays for protein delivery: potential for enhanced intradermal vaccination. J Pharm Pharmacol (2014) 0.83
Increased expression of fibroblast activation protein-alpha in keloid fibroblasts: implications for development of a novel treatment option. Arch Dermatol Res (2010) 0.83
Evaluation of the penetration of 5-aminolevulinic acid through basal cell carcinoma: a pilot study. Exp Dermatol (2004) 0.83
Microneedle-mediated transdermal bacteriophage delivery. Eur J Pharm Sci (2012) 0.83
Pharmaceutical analysis of 5-aminolevulinic acid in solution and in tissues. J Photochem Photobiol B (2005) 0.83
Inhibitor profiling of the Pseudomonas aeruginosa virulence factor LasB using N-alpha mercaptoamide template-based inhibitors. Bioorg Med Chem Lett (2009) 0.83
Modulation of gel formation and drug-release characteristics of lidocaine-loaded poly(vinyl alcohol)-tetraborate hydrogel systems using scavenger polyol sugars. Eur J Pharm Biopharm (2008) 0.83
Antimicrobial peptide incorporated poly(2-hydroxyethyl methacrylate) hydrogels for the prevention of Staphylococcus epidermidis-associated biomaterial infections. J Biomed Mater Res A (2012) 0.82
Hydrogel-forming microneedles increase in volume during swelling in skin, but skin barrier function recovery is unaffected. J Pharm Sci (2014) 0.82