Ian M Clark

Author PubWeight™ 50.14‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 The ADAMTS metalloproteinases. Biochem J 2005 3.95
2 Expression profiling of metalloproteinases and their inhibitors in cartilage. Arthritis Rheum 2004 3.00
3 The role of chondrocyte senescence in osteoarthritis. Aging Cell 2002 2.06
4 The expression and function of microRNAs in chondrogenesis and osteoarthritis. Arthritis Rheum 2011 1.92
5 Class I histone deacetylase inhibition modulates metalloproteinase expression and blocks cytokine-induced cartilage degradation. Arthritis Rheum 2013 1.74
6 Structure, fluctuation and magnitude of a natural grassland soil metagenome. ISME J 2012 1.66
7 Accessing the soil metagenome for studies of microbial diversity. Appl Environ Microbiol 2010 1.53
8 Expression profiling of metalloproteinases and their inhibitors in synovium and cartilage. Arthritis Res Ther 2006 1.51
9 Expression profiling of metalloproteinases and tissue inhibitors of metalloproteinases in normal and degenerate human achilles tendon. Arthritis Rheum 2006 1.48
10 Distribution of environmental mycobacteria in Karonga District, northern Malawi. Appl Environ Microbiol 2006 1.47
11 The comparative role of activator protein 1 and Smad factors in the regulation of Timp-1 and MMP-1 gene expression by transforming growth factor-beta 1. J Biol Chem 2003 1.45
12 Histone deacetylase inhibitors modulate metalloproteinase gene expression in chondrocytes and block cartilage resorption. Arthritis Res Ther 2005 1.37
13 Superoxide dismutase downregulation in osteoarthritis progression and end-stage disease. Ann Rheum Dis 2010 1.25
14 Fungal molecular diagnostics: a mini review. J Appl Genet 2004 1.18
15 Soil pH determines microbial diversity and composition in the park grass experiment. Microb Ecol 2014 1.18
16 Co-induction of glutathione-S-transferases and multidrug resistance associated protein by xenobiotics in wheat. Pest Manag Sci 2003 1.14
17 Analyzing mRNA expression identifies Smad3 as a microRNA-140 target regulated only at protein level. RNA 2010 1.09
18 Matriptase is a novel initiator of cartilage matrix degradation in osteoarthritis. Arthritis Rheum 2010 1.08
19 The use of real-time PCR and species-specific primers for the identification and monitoring of Paecilomyces lilacinus. FEMS Microbiol Ecol 2005 1.07
20 HDAC-mediated control of ERK- and PI3K-dependent TGF-β-induced extracellular matrix-regulating genes. Matrix Biol 2010 1.01
21 Identification of an initiator-like element essential for the expression of the tissue inhibitor of metalloproteinases-4 (Timp-4) gene. Biochem J 2002 1.00
22 Sulforaphane represses matrix-degrading proteases and protects cartilage from destruction in vitro and in vivo. Arthritis Rheum 2013 0.97
23 Fibroblast activation protein alpha is expressed by chondrocytes following a pro-inflammatory stimulus and is elevated in osteoarthritis. Arthritis Res Ther 2006 0.97
24 Review: the role of microRNAs in osteoarthritis and chondrogenesis. Arthritis Rheum 2013 0.96
25 Degradome expression profiling in human articular cartilage. Arthritis Res Ther 2009 0.93
26 Differential effects of histone deacetylase inhibitors on phorbol ester- and TGF-beta1 induced murine tissue inhibitor of metalloproteinases-1 gene expression. FEBS J 2005 0.92
27 Rac upregulates tissue inhibitor of metalloproteinase-1 expression by redox-dependent activation of extracellular signal-regulated kinase signaling. FEBS J 2006 0.91
28 Expression and function of matrix metalloproteinase (MMP)-28. Matrix Biol 2009 0.91
29 Ca. Nitrososphaera and Bradyrhizobium are inversely correlated and related to agricultural practices in long-term field experiments. Front Microbiol 2013 0.90
30 Metalloproteinase gene expression correlates with clinical outcome in Dupuytren's disease. J Hand Surg Am 2008 0.89
31 Activation of p38 and JNK MAPK pathways abrogates requirement for new protein synthesis for phorbol ester mediated induction of select MMP and TIMP genes. Matrix Biol 2007 0.89
32 Expression of metalloproteinases and inhibitors in the differentiation of P19CL6 cells into cardiac myocytes. Biochem Biophys Res Commun 2004 0.87
33 Characterization and regulation of ADAMTS-16. Matrix Biol 2009 0.87
34 A complete expression profile of matrix-degrading metalloproteinases in Dupuytren's disease. J Hand Surg Am 2007 0.86
35 MMP28 gene expression is regulated by Sp1 transcription factor acetylation. Biochem J 2010 0.83
36 MMP-14 and MMP-2 are key metalloproteases in Dupuytren's disease fibroblast-mediated contraction. Biochim Biophys Acta 2012 0.82
37 Transcriptome analysis shows differential gene expression in the saprotrophic to parasitic transition of Pochonia chlamydosporia. Appl Microbiol Biotechnol 2011 0.81
38 Novel WWP2 ubiquitin ligase isoforms as potential prognostic markers and molecular targets in cancer. Biochim Biophys Acta 2013 0.81
39 Matrix metalloproteinase 13 expression in response to double-stranded RNA in human chondrocytes. Arthritis Rheum 2013 0.81
40 A novel method for sampling bacteria on plant root and soil surfaces at the microhabitat scale. J Microbiol Methods 2008 0.77
41 Dietary garlic and hip osteoarthritis: evidence of a protective effect and putative mechanism of action. BMC Musculoskelet Disord 2010 0.77
42 Development of a real-time PCR assay for detection and quantification of Rhizobium leguminosarum bacteria and discrimination between different biovars in zinc-contaminated soil. Appl Environ Microbiol 2011 0.75
43 Expression of recombinant MMP-28 in mammalian cells. Methods Mol Biol 2010 0.75
44 Approaches for monitoring the release of Pochonia chlamydosporia var. catenulata, a biocontrol agent of root-knot nematodes. Mycol Res 2003 0.75
45 Erratum: Pseudomonas spp. diversity is negatively associated with suppression of the wheat take-all pathogen. Sci Rep 2016 0.75