Published in Oncogene on February 10, 2005
Metastasis: recent discoveries and novel treatment strategies. Lancet (2007) 3.93
Transcriptomic dissection of tongue squamous cell carcinoma. BMC Genomics (2008) 2.09
Molecular biology of squamous cell carcinoma of the head and neck. J Clin Pathol (2006) 1.76
TrkB induces EMT and has a key role in invasion of head and neck squamous cell carcinoma. Oncogene (2010) 1.70
Global expression-based classification of lymph node metastasis and extracapsular spread of oral tongue squamous cell carcinoma. Neoplasia (2006) 1.44
Agrin and perlecan mediate tumorigenic processes in oral squamous cell carcinoma. PLoS One (2014) 1.42
Proteomic based identification of manganese superoxide dismutase 2 (SOD2) as a metastasis marker for oral squamous cell carcinoma. Cancer Genomics Proteomics (2008) 1.34
Oral tongue cancer gene expression profiling: Identification of novel potential prognosticators by oligonucleotide microarray analysis. BMC Cancer (2009) 1.30
Pathway and gene-set activation measurement from mRNA expression data: the tissue distribution of human pathways. Genome Biol (2006) 1.29
Endothelial cells enhance tumor cell invasion through a crosstalk mediated by CXC chemokine signaling. Neoplasia (2008) 1.21
A surprising cross-species conservation in the genomic landscape of mouse and human oral cancer identifies a transcriptional signature predicting metastatic disease. Clin Cancer Res (2014) 1.20
Molecular predictors of clinical outcome in patients with head and neck squamous cell carcinoma. Int J Exp Pathol (2005) 1.18
Activation of MAP kinase signaling through ERK5 but not ERK1 expression is associated with lymph node metastases in oral squamous cell carcinoma (OSCC). Neoplasia (2008) 1.17
Examination of oral cancer biomarkers by tissue microarray analysis. Arch Otolaryngol Head Neck Surg (2008) 1.14
Novel p63 target genes involved in paracrine signaling and keratinocyte differentiation. Cell Death Dis (2010) 1.08
Deregulation of Snai2 is associated with metastasis and poor prognosis in tongue squamous cell carcinoma. Int J Cancer (2011) 1.04
PTEN deficiency contributes to the development and progression of head and neck cancer. Neoplasia (2013) 1.03
Deregulation of manganese superoxide dismutase (SOD2) expression and lymph node metastasis in tongue squamous cell carcinoma. BMC Cancer (2010) 0.98
Rewiring of an epithelial differentiation factor, miR-203, to inhibit human squamous cell carcinoma metastasis. Cell Rep (2014) 0.94
KiSS1 mediates platinum sensitivity and metastasis suppression in head and neck squamous cell carcinoma. Oncogene (2011) 0.94
Meta-analysis of multiple microarray datasets reveals a common gene signature of metastasis in solid tumors. BMC Med Genomics (2011) 0.92
Molecular signatures of metastasis in head and neck cancer. Head Neck (2008) 0.89
The effect of a DNA repair gene on cellular invasiveness: XRCC3 over-expression in breast cancer cells. PLoS One (2011) 0.88
Lymphatic metastasis in breast cancer: importance and new insights into cellular and molecular mechanisms. Clin Exp Metastasis (2007) 0.87
Unraveling regulatory programs for NF-kappaB, p53 and microRNAs in head and neck squamous cell carcinoma. PLoS One (2013) 0.86
Searching for molecular markers in head and neck squamous cell carcinomas (HNSCC) by statistical and bioinformatic analysis of larynx-derived SAGE libraries. BMC Med Genomics (2008) 0.85
Clinical relevance of breast cancer-related genes as potential biomarkers for oral squamous cell carcinoma. BMC Cancer (2014) 0.85
Identification and validation of a multigene predictor of recurrence in primary laryngeal cancer. PLoS One (2013) 0.83
Tissue transglutaminase mediates the pro-malignant effects of oncostatin M receptor over-expression in cervical squamous cell carcinoma. J Pathol (2013) 0.83
Low-molecular-mass secretome profiling identifies HMGA2 and MIF as prognostic biomarkers for oral cavity squamous cell carcinoma. Sci Rep (2015) 0.82
Consistent Differential Expression Pattern (CDEP) on microarray to identify genes related to metastatic behavior. BMC Bioinformatics (2011) 0.82
Discovering biological connections between experimental conditions based on common patterns of differential gene expression. BMC Bioinformatics (2011) 0.81
CD44 expression in oro-pharyngeal carcinoma tissues and cell lines. PLoS One (2012) 0.80
SERPINE1 and SMA expression at the invasive front predict extracapsular spread and survival in oral squamous cell carcinoma. Br J Cancer (2014) 0.79
Prognostic biological features in neck dissection specimens. Eur Arch Otorhinolaryngol (2012) 0.79
Signaling Networks of Activated Oncogenic and Altered Tumor Suppressor Genes in Head and Neck Cancer. J Carcinog Mutagen (2013) 0.78
Prediction of disease severity in patients with early rheumatoid arthritis by gene expression profiling. Hum Genomics Proteomics (2009) 0.78
Current potential and limitations of molecular diagnostic methods in head and neck cancer. Eur Arch Otorhinolaryngol (2010) 0.77
Effect of siRNA-mediated downregulation of VEGF in Tca8113 cells on the activity of monocyte-derived dendritic cells. Oncol Lett (2012) 0.77
Classification of heterogeneous microarray data by maximum entropy kernel. BMC Bioinformatics (2007) 0.77
Insulin-like growth factor-independent insulin-like growth factor binding protein 3 promotes cell migration and lymph node metastasis of oral squamous cell carcinoma cells by requirement of integrin β1. Oncotarget (2015) 0.77
Identification of methylation markers for the prediction of nodal metastasis in oral and oropharyngeal squamous cell carcinoma. Epigenetics (2015) 0.77
The effect of red-allotrope selenium nanoparticles on head and neck squamous cell viability and growth. Int J Nanomedicine (2016) 0.76
Genomic analysis to define molecular basis of aggressiveness in a mouse model of oral cancer. Genom Data (2015) 0.76
Revisiting the transcriptional analysis of primary tumours and associated nodal metastases with enhanced biological and statistical controls: application to thyroid cancer. Br J Cancer (2015) 0.76
A microRNA activity map of human mesenchymal tumors: connections to oncogenic pathways; an integrative transcriptomic study. BMC Genomics (2012) 0.76
Integrated network analysis and logistic regression modeling identify stage-specific genes in Oral Squamous Cell Carcinoma. BMC Med Genomics (2015) 0.76
Cellular and bacterial profiles associated with oral epithelium-microbiota interactions. Periodontol 2000 (2010) 0.75
Overexpressed tryptophanyl-tRNA synthetase, an angiostatic protein, enhances oral cancer cell invasiveness. Oncotarget (2015) 0.75
Prediction of biomarkers of oral squamous cell carcinoma using microarray technology. Sci Rep (2017) 0.75
Possibility of the use of public microarray database for identifying significant genes associated with oral squamous cell carcinoma. Genomics Inform (2012) 0.75
MFAP5 and TNNC1: Potential markers for predicting occult cervical lymphatic metastasis and prognosis in early stage tongue cancer. Oncotarget (2016) 0.75
BRD4 promotes p63 and GRHL3 expression downstream of FOXO in mammary epithelial cells. Nucleic Acids Res (2016) 0.75
TNF-α modulates genome-wide redistribution of ΔNp63α/TAp73 and NF-κB cREL interactive binding on TP53 and AP-1 motifs to promote an oncogenic gene program in squamous cancer. Oncogene (2016) 0.75
Protein S drives oral squamous cell carcinoma tumorigenicity through regulation of AXL. Oncotarget (2017) 0.75
Human papillomavirus and survival of patients with oropharyngeal cancer. N Engl J Med (2010) 22.74
Concurrent chemotherapy and radiotherapy for organ preservation in advanced laryngeal cancer. N Engl J Med (2003) 13.99
BRAF and RAS mutations in human lung cancer and melanoma. Cancer Res (2002) 8.55
Racial differences in the use of BRCA1/2 testing among women with a family history of breast or ovarian cancer. JAMA (2005) 4.93
Evolving options in the management of esophageal perforation. Ann Thorac Surg (2004) 4.12
A distinct macrophage population mediates metastatic breast cancer cell extravasation, establishment and growth. PLoS One (2009) 3.86
The value of resident presentations at scientific meetings. Laryngoscope (2013) 3.48
miR-182-mediated downregulation of BRCA1 impacts DNA repair and sensitivity to PARP inhibitors. Mol Cell (2010) 3.27
caTIES: a grid based system for coding and retrieval of surgical pathology reports and tissue specimens in support of translational research. J Am Med Inform Assoc (2010) 2.62
Expectation-maximization-driven geodesic active contour with overlap resolution (EMaGACOR): application to lymphocyte segmentation on breast cancer histopathology. IEEE Trans Biomed Eng (2010) 2.52
A boosted Bayesian multiresolution classifier for prostate cancer detection from digitized needle biopsies. IEEE Trans Biomed Eng (2010) 2.41
A novel approach to eliminate cardiac perforation in the nuss procedure. Ann Thorac Surg (2013) 2.28
Differences in the patterns of health care system distrust between blacks and whites. J Gen Intern Med (2008) 2.20
Hormone action in the mammary gland. Cold Spring Harb Perspect Biol (2010) 2.10
Coagulation facilitates tumor cell spreading in the pulmonary vasculature during early metastatic colony formation. Cancer Res (2004) 2.07
Local recurrence in head and neck cancer: relationship to radiation resistance and signal transduction. Clin Cancer Res (2002) 2.05
Histone deacetylase 4 interacts with 53BP1 to mediate the DNA damage response. J Cell Biol (2003) 1.92
Digital imaging in pathology: whole-slide imaging and beyond. Annu Rev Pathol (2012) 1.89
Current management of esophageal leiomyoma. J Am Coll Surg (2004) 1.82
HIV protease inhibitors block Akt signaling and radiosensitize tumor cells both in vitro and in vivo. Cancer Res (2005) 1.81
Mesenchymal stem cells prevent the rejection of fully allogenic islet grafts by the immunosuppressive activity of matrix metalloproteinase-2 and -9. Diabetes (2009) 1.78
Racial/ethnic differences in physician distrust in the United States. Am J Public Health (2007) 1.78
Tumor cell alpha3beta1 integrin and vascular laminin-5 mediate pulmonary arrest and metastasis. J Cell Biol (2004) 1.72
Radiation sensitization of human cancer cells in vivo by inhibiting the activity of PI3K using LY294002. Int J Radiat Oncol Biol Phys (2003) 1.68
Folate receptor alpha expression in lung cancer: diagnostic and prognostic significance. Oncotarget (2012) 1.67
A small interfering RNA screen of genes involved in DNA repair identifies tumor-specific radiosensitization by POLQ knockdown. Cancer Res (2010) 1.65
Endoscopic resection of sinonasal cancers with and without craniotomy: oncologic results. Arch Otolaryngol Head Neck Surg (2009) 1.64
Multivariate predictors of occult neck metastasis in early oral tongue cancer. Otolaryngol Head Neck Surg (2004) 1.63
Delta-like ligand 4-notch blockade and tumor radiation response. J Natl Cancer Inst (2011) 1.62
Novel MMP-9 substrates in cancer cells revealed by a label-free quantitative proteomics approach. Mol Cell Proteomics (2008) 1.60
Registering histologic and MR images of prostate for image-based cancer detection. Acad Radiol (2007) 1.58
Sleeve lobectomy: current indications and future directions. Ann Thorac Cardiovasc Surg (2010) 1.58
Cellular adaptive inflammation mediates airway granulation in a murine model of subglottic stenosis. Otolaryngol Head Neck Surg (2011) 1.58
A boosting cascade for automated detection of prostate cancer from digitized histology. Med Image Comput Comput Assist Interv (2006) 1.57
A segment of gamma ENaC mediates elastase activation of Na+ transport. J Gen Physiol (2007) 1.57
Protease nexin 1 inhibits hedgehog signaling in prostate adenocarcinoma. J Clin Invest (2012) 1.57
Clinical trial resources on the internet must be designed to reach underrepresented minorities. Cancer J (2007) 1.56
Complete resection of pulmonary inflammatory pseudotumors has excellent long-term prognosis. J Thorac Cardiovasc Surg (2008) 1.56
A comparison of the behavior of (64)Cu-acetate and (64)Cu-ATSM in vitro and in vivo. J Nucl Med (2013) 1.55
Proteases, extracellular matrix, and cancer: a workshop of the path B study section. Am J Pathol (2004) 1.52
Inhibition of KSHV-infected primary effusion lymphomas in NOD/SCID mice by gamma-secretase inhibitor. Cancer Biol Ther (2009) 1.52
IMRT reirradiation of head and neck cancer-disease control and morbidity outcomes. Int J Radiat Oncol Biol Phys (2008) 1.51
Monocyte chemoattractant protein-1 blockade inhibits lung cancer tumor growth by altering macrophage phenotype and activating CD8+ cells. Am J Respir Cell Mol Biol (2010) 1.51
Effect of framing as gain versus loss on understanding and hypothetical treatment choices: survival and mortality curves. Med Decis Making (2002) 1.48
CCL2 blockade augments cancer immunotherapy. Cancer Res (2009) 1.48
Hand-held spectroscopic device for in vivo and intraoperative tumor detection: contrast enhancement, detection sensitivity, and tissue penetration. Anal Chem (2010) 1.47
Farnesyltransferase inhibitors: an overview of the results of preclinical and clinical investigations. Cancer Res (2003) 1.46
Selective inhibition of Ras, phosphoinositide 3 kinase, and Akt isoforms increases the radiosensitivity of human carcinoma cell lines. Cancer Res (2005) 1.41
Gene expression profiling of the early pulmonary response to hyperoxia in mice. Am J Respir Cell Mol Biol (2003) 1.41
Transcriptomic analysis comparing tumor-associated neutrophils with granulocytic myeloid-derived suppressor cells and normal neutrophils. PLoS One (2012) 1.40
Intravascular location of breast cancer cells after spontaneous metastasis to the lung. Am J Pathol (2002) 1.40
Changes in the local tumor microenvironment in recurrent cancers may explain the failure of vaccines after surgery. Proc Natl Acad Sci U S A (2012) 1.40
C-Raf-1 protein kinase is not essential for Ras transformation of mouse embryo fibroblasts. Cancer Biol Ther (2003) 1.39
MicroRNA expression profiling outperforms mRNA expression profiling in formalin-fixed paraffin-embedded tissues. Int J Clin Exp Pathol (2009) 1.38
Pulse steroid therapy inhibits murine subglottic granulation. Otolaryngol Head Neck Surg (2012) 1.38
Does not topical airway lidocaine before endotracheal intubation decrease the risk of perioperative respiratory adverse events in children? Paediatr Anaesth (2012) 1.38
Giant bullous lung disease: evaluation, selection, techniques, and outcomes. Chest Surg Clin N Am (2003) 1.37
A novel endocrine-disrupting agent in corn with mitogenic activity in human breast and prostatic cancer cells. Environ Health Perspect (2002) 1.36
The novel ATR inhibitor VE-821 increases sensitivity of pancreatic cancer cells to radiation and chemotherapy. Cancer Biol Ther (2012) 1.35
Gene induction during differentiation of human pulmonary type II cells in vitro. Am J Respir Cell Mol Biol (2006) 1.35
Tumor vascular changes mediated by inhibition of oncogenic signaling. Cancer Res (2009) 1.35
Gene profiling of human adipose tissue during evoked inflammation in vivo. Diabetes (2009) 1.34
Transoral robotic surgery and human papillomavirus status: Oncologic results. Head Neck (2010) 1.33
Tumor-associated neutrophils stimulate T cell responses in early-stage human lung cancer. J Clin Invest (2014) 1.33
The Cancer Biomedical Informatics Grid (caBIG<sup>TM</sup>). Conf Proc IEEE Eng Med Biol Soc (2005) 1.33
Cancer cells that survive radiation therapy acquire HIF-1 activity and translocate towards tumour blood vessels. Nat Commun (2012) 1.30
Intraoperative near-infrared imaging of surgical wounds after tumor resections can detect residual disease. Clin Cancer Res (2012) 1.30
Dual inhibition of the PI3K/mTOR pathway increases tumor radiosensitivity by normalizing tumor vasculature. Cancer Res (2011) 1.30
The role of adjuvant radiotherapy in the local management of desmoplastic melanoma. Cancer (2013) 1.28
An overview of marine biodiversity in United States waters. PLoS One (2010) 1.27
Recruitment of a myeloid cell subset (CD11b/Gr1 mid) via CCL2/CCR2 promotes the development of colorectal cancer liver metastasis. Hepatology (2013) 1.25
Chemotherapy delivered after viral immunogene therapy augments antitumor efficacy via multiple immune-mediated mechanisms. Mol Ther (2010) 1.23
Cdc42 promotes transendothelial migration of cancer cells through β1 integrin. J Cell Biol (2012) 1.20
A paradigm shift for sternal reconstruction using a novel titanium rib bridge system following oncological resections. Eur J Cardiothorac Surg (2012) 1.20
An active learning based classification strategy for the minority class problem: application to histopathology annotation. BMC Bioinformatics (2011) 1.20
Salinomycin induces cell death with autophagy through activation of endoplasmic reticulum stress in human cancer cells. Autophagy (2013) 1.19
A phase II trial of intraperitoneal photodynamic therapy for patients with peritoneal carcinomatosis and sarcomatosis. Clin Cancer Res (2006) 1.19
Lymphatic invasion revealed by multispectral imaging is common in primary melanomas and associates with prognosis. Hum Pathol (2008) 1.19
Co-compartmentalization of the astroglial glutamate transporter, GLT-1, with glycolytic enzymes and mitochondria. J Neurosci (2011) 1.18
HistoStitcher(©): an interactive program for accurate and rapid reconstruction of digitized whole histological sections from tissue fragments. Comput Med Imaging Graph (2011) 1.18
Inhibition of centrosome separation after DNA damage: a role for Nek2. Radiat Res (2004) 1.18
ATF4-dependent induction of heme oxygenase 1 prevents anoikis and promotes metastasis. J Clin Invest (2015) 1.17
Progesterone receptors mediate male aggression toward infants. Proc Natl Acad Sci U S A (2003) 1.17
Melanoma seeding of an EUS-guided fine needle track. Gastrointest Endosc (2004) 1.17
Increased proteolysis, myosin depletion, and atrophic AKT-FOXO signaling in human diaphragm disuse. Am J Respir Crit Care Med (2010) 1.16
Local and systemic recurrence is the Achilles heel of cancer surgery. Ann Surg Oncol (2011) 1.15
Calcyclin-binding protein inhibits proliferation, tumorigenicity, and invasion of gastric cancer. Mol Cancer Res (2007) 1.14
The incidence of concurrent osteitis in patients with chronic rhinosinusitis: a clinicopathological study. Am J Rhinol (2006) 1.14
Integrated diagnostics: a conceptual framework with examples. Clin Chem Lab Med (2010) 1.14
MicroRNA expression profiles of whole blood in lung adenocarcinoma. PLoS One (2012) 1.13
Identification of intrinsic imaging phenotypes for breast cancer tumors: preliminary associations with gene expression profiles. Radiology (2014) 1.12
Detection of THCA in oral fluid by GC-MS-MS. J Anal Toxicol (2006) 1.12
Targeting ATR in DNA damage response and cancer therapeutics. Cancer Treat Rev (2013) 1.12
Novel recombinant human b7-h4 antibodies overcome tumoral immune escape to potentiate T-cell antitumor responses. Cancer Res (2013) 1.11
Live cell imaging reveals distinct roles in cell cycle regulation for Nek2A and Nek2B. Biochim Biophys Acta (2005) 1.11
The RAS signal transduction pathway and its role in radiation sensitivity. Oncogene (2003) 1.11
B cell depletion with anti-CD79 mAbs ameliorates autoimmune disease in MRL/lpr mice. J Immunol (2008) 1.11