Published in Acta Crystallogr D Biol Crystallogr on November 26, 2004
Phaser crystallographic software. J Appl Crystallogr (2007) 108.34
Features and development of Coot. Acta Crystallogr D Biol Crystallogr (2010) 89.46
Overview of the CCP4 suite and current developments. Acta Crystallogr D Biol Crystallogr (2011) 67.55
Presenting your structures: the CCP4mg molecular-graphics software. Acta Crystallogr D Biol Crystallogr (2011) 6.27
RNABC: forward kinematics to reduce all-atom steric clashes in RNA backbone. J Math Biol (2007) 4.12
Discovery of novel DNA gyrase inhibitors by high-throughput virtual screening. Antimicrob Agents Chemother (2007) 1.02
Structural basis for phosphorylation-dependent recruitment of Tel2 to Hsp90 by Pih1. Structure (2014) 1.00
Reintroducing electrostatics into macromolecular crystallographic refinement: application to neutron crystallography and DNA hydration. Structure (2011) 0.98
Structure of the TPR domain of AIP: lack of client protein interaction with the C-terminal α-7 helix of the TPR domain of AIP is sufficient for pituitary adenoma predisposition. PLoS One (2012) 0.96
Ground state destabilization from a positioned general base in the ketosteroid isomerase active site. Biochemistry (2013) 0.96
Use of anion-aromatic interactions to position the general base in the ketosteroid isomerase active site. Proc Natl Acad Sci U S A (2013) 0.94
Human Cytochrome P450 21A2, the Major Steroid 21-Hydroxylase: STRUCTURE OF THE ENZYME·PROGESTERONE SUBSTRATE COMPLEX AND RATE-LIMITING C-H BOND CLEAVAGE. J Biol Chem (2015) 0.90
Uncovering the determinants of a highly perturbed tyrosine pKa in the active site of ketosteroid isomerase. Biochemistry (2013) 0.85
LpxI structures reveal how a lipid A precursor is synthesized. Nat Struct Mol Biol (2012) 0.83
Characterization of the yellow fever mosquito sterol carrier protein-2 like 3 gene and ligand-bound protein structure. Mol Cell Biochem (2009) 0.83
Internal binding of halogenated phenols in dehaloperoxidase-hemoglobin inhibits peroxidase function. Biophys J (2010) 0.81
Influence of naturally-occurring 5'-pyrophosphate-linked substituents on the binding of adenylic inhibitors to ribonuclease a: an X-ray crystallographic study. Biopolymers (2009) 0.81
Evaluating the therapeutic potential of a non-natural nucleotide that inhibits human ribonucleotide reductase. Mol Cancer Ther (2012) 0.79
X-ray crystallography and isothermal titration calorimetry studies of the Salmonella zinc transporter ZntB. Structure (2011) 0.79
Crystal structures of Streptococcus pyogenes Dpr reveal a dodecameric iron-binding protein with a ferroxidase site. J Biol Inorg Chem (2009) 0.79
Unusual Base-Pairing Interactions in Monomer-Template Complexes. ACS Cent Sci (2016) 0.78
Common and distant structural characteristics of feruloyl esterase families from Aspergillus oryzae. PLoS One (2012) 0.77
A model for the flexibility of the distal histidine in dehaloperoxidase-hemoglobin A based on X-ray crystal structures of the carbon monoxide adduct. Biochemistry (2014) 0.75
Conformational transition paths harbor structures useful for aiding drug discovery and understanding enzymatic mechanisms in protein kinases. Protein Sci (2015) 0.75
Functional consequences of the open distal pocket of dehaloperoxidase-hemoglobin observed by time-resolved X-ray crystallography. Biochemistry (2013) 0.75
Influence of vitamin D deficiency and vitamin D receptor polymorphisms on tuberculosis among Gujarati Asians in west London: a case-control study. Lancet (2000) 7.25
Structural model of ATP-binding proteins associated with cystic fibrosis, multidrug resistance and bacterial transport. Nature (1990) 6.41
Ongoing developments in CCP4 for high-throughput structure determination. Acta Crystallogr D Biol Crystallogr (2002) 4.99
Prenatal sex determination by DNA amplification from maternal peripheral blood. Lancet (1989) 4.42
C reactive protein and its relation to cardiovascular risk factors: a population based cross sectional study. BMJ (1996) 3.61
The integration host factor of Escherichia coli binds to bent DNA at the origin of replication of the plasmid pSC101. Cell (1987) 3.06
11C-PIB PET imaging in Alzheimer disease and frontotemporal lobar degeneration. Neurology (2007) 2.65
Linkage of type 2 diabetes to the glucokinase gene. Lancet (1992) 2.64
Differential methylation of hypoxanthine phosphoribosyltransferase genes on active and inactive human X chromosomes. Proc Natl Acad Sci U S A (1984) 2.52
Relation of serum cytokine concentrations to cardiovascular risk factors and coronary heart disease. Heart (1997) 2.50
Polymorphic haplotypes of the interleukin-10 5' flanking region determine variable interleukin-10 transcription and are associated with particular phenotypes of juvenile rheumatoid arthritis. Arthritis Rheum (1999) 2.39
Fibrinogen: a link between chronic infection and coronary heart disease. Lancet (1994) 2.19
Chemo-ablation of the prostate with dehydrated alcohol for the treatment of prostatic obstruction. J Urol (2002) 2.06
British American Tobacco and the "insidious impact of illicit trade" in cigarettes across Africa. Tob Control (2008) 2.02
Influence of polymorphism in the genes for the interleukin (IL)-1 receptor antagonist and IL-1beta on tuberculosis. J Exp Med (1999) 1.97
Vascular and metabolic response to isolated small muscle mass exercise: effect of age. Am J Physiol Heart Circ Physiol (2003) 1.97
Detection of single-copy fetal DNA sequence from maternal blood. Lancet (1990) 1.85
The vesicle transport protein Vps33p is an ATP-binding protein that localizes to the cytosol in an energy-dependent manner. J Biol Chem (1998) 1.81
Phase II trial of paclitaxel, fluorouracil, and cisplatin in patients with advanced carcinoma of the esophagus. J Clin Oncol (1998) 1.80
Thyroidal trophic influence on skeletal muscle myosin. Nature (1977) 1.79
An outbreak of syphilis in Alabama prisons: correctional health policy and communicable disease control. Am J Public Health (2001) 1.73
Effect of Helicobacter pylori eradication on gastric metaplasia of the duodenum. Gut (1995) 1.72
Gut-associated lymphoid tissue contains the molecular machinery to support T-cell-dependent and T-cell-independent class switch recombination. Mucosal Immunol (2009) 1.72
Swallowed foreign bodies. J Laryngol Otol (1988) 1.69
ErbB-2 inhibition activates Notch-1 and sensitizes breast cancer cells to a gamma-secretase inhibitor. Oncogene (2008) 1.69
Chlamydia pneumoniae: risk factors for seropositivity and association with coronary heart disease. J Infect (1995) 1.69
Importance of ribosomal frameshifting for human immunodeficiency virus type 1 particle assembly and replication. J Virol (1998) 1.61
Isolation and characterization of mutant strains of Escherichia coli altered in H2 metabolism. J Bacteriol (1985) 1.61
On using the linear-quadratic model in daily clinical practice. Int J Radiat Oncol Biol Phys (1991) 1.56
Herniation through a donor site for iliac bone graft. J R Coll Surg Edinb (1987) 1.47
First trimester screening of maternal placental protein 13 for predicting preeclampsia and small for gestational age: in-house study and systematic review. Placenta (2012) 1.45
Presence of Epstein-Barr virus receptors, but absence of virus penetration, in cells of an Epstein-Barr virus genome-negative human lymphoblastoid T line (Molt 4). J Virol (1977) 1.44
Elevated cytokine and chemokine levels and prolonged pulmonary airflow resistance in a murine Mycoplasma pneumoniae pneumonia model: a microbiologic, histologic, immunologic, and respiratory plethysmographic profile. Infect Immun (2001) 1.44
Management of Mersilene mesh chronic eyelid complications: a systematic approach. Eye (Lond) (2004) 1.44
Clinical and hematologic effects of hydroxyurea in children with sickle cell anemia. J Pediatr (1996) 1.44
An upper limit on the stochastic gravitational-wave background of cosmological origin. Nature (2009) 1.42
The crystal structure of tetanus toxin Hc fragment complexed with a synthetic GT1b analogue suggests cross-linking between ganglioside receptors and the toxin. J Biol Chem (2001) 1.42
Brain atrophy in Werdnig-Hoffmann disease. Acta Neurol Scand (1991) 1.41
Helicobacter pylori infection density and gastric inflammation in duodenal ulcer and non-ulcer subjects. Gut (1995) 1.39
Coinjection strategy for visual identification of transgenic mice. Transgenic Res (1991) 1.27
The cytoplasmic and transmembrane domains of the p75 and Trk A receptors regulate high affinity binding to nerve growth factor. J Biol Chem (2001) 1.25
Functional results and complications of Mersilene mesh use for frontalis suspension ptosis surgery. Br J Ophthalmol (2004) 1.25
Association of isolated short femur in the mid-trimester fetus with perinatal outcome. Ultrasound Obstet Gynecol (2008) 1.24
ARC, an apoptosis suppressor limited to terminally differentiated cells, is induced in human breast cancer and confers chemo- and radiation-resistance. Cell Death Differ (2005) 1.23
Direct haplotype determination by double ARMS: specificity, sensitivity and genetic applications. Nucleic Acids Res (1991) 1.22
Reliability and validity of the PAS-ADD Checklist for detecting psychiatric disorders in adults with intellectual disability. J Intellect Disabil Res (1998) 1.21
Measuring visual neglect in acute stroke and predicting its recovery: the visual neglect recovery index. J Neurol Neurosurg Psychiatry (1992) 1.21
Differential anti-inflammatory effects of immunosuppressive drugs: cyclosporin, rapamycin and FK-506 on inducible nitric oxide synthase, nitric oxide, cyclooxygenase-2 and PGE2 production. Inflamm Res (2000) 1.21
A host-encoded DNA-binding protein promotes termination of plasmid replication at a sequence-specific replication terminus. Proc Natl Acad Sci U S A (1989) 1.20
ChlVPP combination chemotherapy for Hodgkin's disease: long-term results. Br J Cancer (1990) 1.17
SPINE workshop on automated X-ray analysis: a progress report. Acta Crystallogr D Biol Crystallogr (2006) 1.17
External quality assessment for detection of Chlamydia trachomatis. J Clin Microbiol (2005) 1.16
Effects of side-posture positioning and side-posture adjusting on the lumbar zygapophysial joints as evaluated by magnetic resonance imaging: a before and after study with randomization. J Manipulative Physiol Ther (2000) 1.15
Mental health and psychosocial support in crisis and conflict: report of the Mental Health Working Group. Prehosp Disaster Med (2009) 1.13
Factors associated with prevalent abnormal anal cytology in a large cohort of HIV-infected adults in the United States. J Infect Dis (2010) 1.12
Clinical characteristics of subjects with a missense mutation in glucokinase. Diabet Med (1995) 1.09
The magnetic immuno-polymerase chain reaction assay for the detection of Campylobacter in milk and poultry. Lett Appl Microbiol (1996) 1.07
Missense glucokinase mutation in maturity-onset diabetes of the young and mutation screening in late-onset diabetes. Nat Genet (1992) 1.06
Clinical dashboards in otolaryngology. Clin Otolaryngol (2010) 1.05
Use of biotin-labeled nucleic acids for protein purification and agarose-based chemiluminescent electromobility shift assays. Anal Biochem (2000) 1.05
Metal stents improve dysphagia, nutrition and survival in malignant oesophageal stenosis: a randomized controlled trial comparing modified Gianturco Z-stents with plastic Atkinson tubes. Eur J Gastroenterol Hepatol (1998) 1.04
Detection of mutations in insulin-receptor gene in NIDDM patients by analysis of single-stranded conformation polymorphisms. Diabetes (1991) 1.04
Pathogenesis of gastric metaplasia of the human duodenum: role of Helicobacter pylori, gastric acid, and ulceration. Gastroenterology (1996) 1.04
The TWIST gene, although not disrupted in Saethre-Chotzen patients with apparently balanced translocations of 7p21, is mutated in familial and sporadic cases. Hum Mol Genet (1997) 1.03
Modulation by epitope-specific antibodies of class II MHC-restricted presentation of the tetanus toxin antigen. Immunol Rev (1998) 1.03
The effects of unsaturated fatty acids on Helicobacter pylori in vitro. J Med Microbiol (1995) 1.02
Caloric restriction and body weight independently affect longevity in Wistar rats. Int J Obes Relat Metab Disord (2004) 1.02
Increasing parental provision and children's consumption of lunchbox fruit and vegetables in Ireland: the Food Dudes intervention. Eur J Clin Nutr (2008) 1.01
Stereochemistry of carbon monoxide binding to normal human adult and Cowtown haemoglobins. J Mol Biol (1990) 1.01
A randomized trial of endoscopy vs no endoscopy in the management of seronegative Helicobacter pylori dyspepsia. Eur J Gastroenterol Hepatol (1998) 1.01
The treatment of moderate to severe psoriasis with a new anti-CD11a monoclonal antibody. J Am Acad Dermatol (2001) 1.01
Medical student suicide, 1989-1994. Am J Psychiatry (1996) 1.01
HIV-1 gp120/160 expressing cells upregulate HIV-1 LTR directed gene expression in a cell line transfected with HIV-1 LTR-reporter gene constructs. Cell Mol Biol (Noisy-le-grand) (1995) 1.01
Increased bone metabolism in rheumatoid arthritis as measured by the whole-body retention of 99Tcm methylene diphosphonate. Ann Rheum Dis (1983) 1.00
Maintenance of asthma control by once-daily inhaled ciclesonide in adults with persistent asthma. Allergy (2005) 0.99
Classification of Vibrio vulnificus strains by the carbohydrate composition of their capsular polysaccharides. Anal Biochem (1997) 0.99
Management of cervical lymph nodes in patients with head and neck cancer. Eur Arch Otorhinolaryngol (1992) 0.98
Purification and characterization of two forms of hydrogenase isoenzyme 1 from Escherichia coli. J Bacteriol (1990) 0.98
Notch signalling and voltage-gated Na+ channel activity in human prostate cancer cells: independent modulation of in vitro motility. Prostate Cancer Prostatic Dis (2006) 0.98
Prenatal sex determination from maternal peripheral blood using the polymerase chain reaction. Hum Genet (1993) 0.97
Reliability and validity of the Mini PAS-ADD for assessing psychiatric disorders in adults with intellectual disability. J Intellect Disabil Res (1998) 0.96
Pharmacogenetics: the therapeutic drug monitoring of the future? Clin Pharmacokinet (2001) 0.96
Airborne dissemination of Burkholderia (Pseudomonas) cepacia from adult patients with cystic fibrosis. Thorax (1994) 0.95
Hemifacial microsomia. Etiology, diagnosis and treatment. J Am Dent Assoc (2001) 0.95
Imaging characteristics of recurrent pleomorphic adenoma of the parotid gland. AJNR Am J Neuroradiol (2007) 0.94
Cisplatin enhances the antitumor effect of tumor necrosis factor-related apoptosis-inducing ligand gene therapy via recruitment of the mitochondria-dependent death signaling pathway. Cancer Gene Ther (2008) 0.94
Natural history and prognostic factors for survival in patients with acquired immune deficiency syndrome (AIDS)-related primary central nervous system lymphoma (PCNSL). Crit Rev Oncog (1998) 0.94
Flotillin 2 is distinct from epidermal surface antigen (ESA) and is associated with filopodia formation. J Cell Biochem (1999) 0.94
A micro-method for measuring total protein in cerebrospinal fluid by using benzethonium chloride in microtiter plate wells. Clin Chem (1989) 0.94
Adherence to oral montelukast and inhaled fluticasone in children with persistent asthma. Pharmacotherapy (2001) 0.93
Directional limits on persistent gravitational waves using LIGO S5 science data. Phys Rev Lett (2011) 0.93
Effect of interferon on lymphocyte transformation and nuclear antigen production by Epstein-Barr virus. Nature (1976) 0.93
Mucin subclasses in ulcerative colitis. Gastroenterology (1987) 0.93
An immunohistological study of cytokeratin 20 in human and mammalian oral epithelium. Arch Oral Biol (2000) 0.93
Association between depression and nonadherence in recipients of kidney transplants: analysis of the United States renal data system. Transplant Proc (2009) 0.92
Mucoid encapsulated Enterococcus faecalis: an emerging morphotype isolated from patients with urinary tract infections. Diagn Microbiol Infect Dis (1998) 0.92
Dense cells in sickle cell anemia: the effects of gene interaction. Blood (1984) 0.91