Published in J Am Soc Nephrol on December 01, 2004
Nephrin ectodomain engagement results in Src kinase activation, nephrin phosphorylation, Nck recruitment, and actin polymerization. J Clin Invest (2006) 3.23
Myoblast fusion: lessons from flies and mice. Development (2012) 2.66
Nck proteins maintain the adult glomerular filtration barrier. J Am Soc Nephrol (2009) 1.92
Neph1 cooperates with nephrin to transduce a signal that induces actin polymerization. Mol Cell Biol (2007) 1.72
Nephrin deficiency activates NF-kappaB and promotes glomerular injury. J Am Soc Nephrol (2009) 1.57
Nephrin Tyrosine Phosphorylation Is Required to Stabilize and Restore Podocyte Foot Process Architecture. J Am Soc Nephrol (2016) 1.50
Activation of RhoA in podocytes induces focal segmental glomerulosclerosis. J Am Soc Nephrol (2011) 1.44
beta-Arrestin2 mediates nephrin endocytosis and impairs slit diaphragm integrity. Proc Natl Acad Sci U S A (2006) 1.43
Phosphorylated YDXV motifs and Nck SH2/SH3 adaptors act cooperatively to induce actin reorganization. Mol Cell Biol (2008) 1.34
Phosphorylation of nephrin triggers its internalization by raft-mediated endocytosis. J Am Soc Nephrol (2009) 1.30
Crk1/2-dependent signaling is necessary for podocyte foot process spreading in mouse models of glomerular disease. J Clin Invest (2012) 1.25
The podocyte slit diaphragm--from a thin grey line to a complex signalling hub. Nat Rev Nephrol (2013) 1.12
Signaling from the podocyte intercellular junction to the actin cytoskeleton. Semin Nephrol (2012) 1.07
Glomerular diseases: genetic causes and future therapeutics. Nat Rev Nephrol (2010) 1.03
Angiotensin II induces nephrin dephosphorylation and podocyte injury: role of caveolin-1. Cell Signal (2011) 0.99
Planar cell polarity pathway regulates nephrin endocytosis in developing podocytes. J Biol Chem (2013) 0.93
TRPC6 in glomerular health and disease: what we know and what we believe. Semin Cell Dev Biol (2006) 0.93
Direct regulation of nephrin tyrosine phosphorylation by Nck adaptor proteins. J Biol Chem (2012) 0.92
The structural and functional organization of the podocyte filtration slits is regulated by Tjp1/ZO-1. PLoS One (2014) 0.87
Podocyte Protein, Nephrin, Is a Substrate of Protein Tyrosine Phosphatase 1B. J Signal Transduct (2011) 0.87
Dynamin-mediated Nephrin phosphorylation regulates glucose-stimulated insulin release in pancreatic beta cells. J Biol Chem (2012) 0.87
Claudins reign: The claudin/EMP/PMP22/γ channel protein family in C. elegans. Tissue Barriers (2013) 0.87
Podocyte-actin dynamics in health and disease. Nat Rev Nephrol (2016) 0.85
Membrane trafficking in podocyte health and disease. Pediatr Nephrol (2012) 0.84
Tyrosine kinase signaling in kidney glomerular podocytes. J Signal Transduct (2011) 0.83
Nephrin Contributes to Insulin Secretion and Affects Mammalian Target of Rapamycin Signaling Independently of Insulin Receptor. J Am Soc Nephrol (2015) 0.81
Shp2 Associates with and Enhances Nephrin Tyrosine Phosphorylation and Is Necessary for Foot Process Spreading in Mouse Models of Podocyte Injury. Mol Cell Biol (2015) 0.81
Dexamethasone increases the phosphorylation of nephrin in cultured podocytes. Clin Exp Nephrol (2011) 0.81
Podocyte injury and albuminuria in mice with podocyte-specific overexpression of the Ste20-like kinase, SLK. Am J Pathol (2010) 0.81
TM4SF10 and ADAP interaction in podocytes: role in Fyn activity and nephrin phosphorylation. Am J Physiol Cell Physiol (2011) 0.80
Increased SHP-1 protein expression by high glucose levels reduces nephrin phosphorylation in podocytes. J Biol Chem (2014) 0.80
Kin of IRRE-like Protein 2 Is a Phosphorylated Glycoprotein That Regulates Basal Insulin Secretion. J Biol Chem (2015) 0.79
Phosphorylation status of nephrin in human membranous nephropathy. Clin Exp Nephrol (2009) 0.79
Endocytic Trafficking at the Mature Podocyte Slit Diaphragm. Front Pediatr (2017) 0.78
Podocytes: the Weakest Link in Diabetic Kidney Disease? Curr Diab Rep (2016) 0.77
Fyn Mediates High Glucose-Induced Actin Cytoskeleton Reorganization of Podocytes via Promoting ROCK Activation In Vitro. J Diabetes Res (2016) 0.76
A biomimetic gelatin-based platform elicits a pro-differentiation effect on podocytes through mechanotransduction. Sci Rep (2017) 0.76
Vertebrate Claudin/PMP22/EMP22/MP20 family protein TMEM47 regulates epithelial cell junction maturation and morphogenesis. Dev Dyn (2016) 0.75
Integrin Ligation Results in Nephrin Tyrosine Phosphorylation In Vitro. PLoS One (2016) 0.75
Angiotensin II down-regulates nephrin-Akt signaling and induces podocyte injury: roleof c-Abl. Mol Biol Cell (2015) 0.75
Nephrin Suppresses Hippo Signaling through the Adaptor Proteins Nck and WTIP. J Biol Chem (2016) 0.75
ARF6 mediates nephrin tyrosine phosphorylation-induced podocyte cellular dynamics. PLoS One (2017) 0.75
Src family kinases in chronic kidney disease. Am J Physiol Renal Physiol (2017) 0.75
Nck adaptor proteins link nephrin to the actin cytoskeleton of kidney podocytes. Nature (2006) 4.05
Perceived knowledge among patients cared for by nephrologists about chronic kidney disease and end-stage renal disease therapies. Kidney Int (2008) 3.36
Nck proteins maintain the adult glomerular filtration barrier. J Am Soc Nephrol (2009) 1.92
Role of the retinoic acid receptor-α in HIV-associated nephropathy. Kidney Int (2010) 1.89
Real-time in vivo virtual histology of colorectal lesions when using the endocytoscopy system. Gastrointest Endosc (2006) 1.84
Expression of podocyte-associated molecules in acquired human kidney diseases. J Am Soc Nephrol (2003) 1.79
Health-related quality of life in CKD Patients: correlates and evolution over time. Clin J Am Soc Nephrol (2009) 1.72
Disparate effects of angiotensin II antagonists and calcium channel blockers on albuminuria in experimental diabetes and hypertension: potential role of nephrin. J Hypertens (2003) 1.70
Urinary sediment podocalyxin in children with glomerular diseases. Nephron Clin Pract (2003) 1.64
Mitochondrial Dok-4 recruits Src kinase and regulates NF-kappaB activation in endothelial cells. J Biol Chem (2005) 1.59
Endoplasmic reticulum stress in glomerular epithelial cell injury. Am J Physiol Renal Physiol (2010) 1.52
Role of p38 mitogen-activated protein kinase activation in podocyte injury and proteinuria in experimental nephrotic syndrome. J Am Soc Nephrol (2005) 1.47
Activation of RhoA in podocytes induces focal segmental glomerulosclerosis. J Am Soc Nephrol (2011) 1.44
Podocyte as the target for aldosterone: roles of oxidative stress and Sgk1. Hypertension (2007) 1.43
Pathophysiologic implications of reduced podocyte number in a rat model of progressive glomerular injury. Am J Pathol (2006) 1.41
Blockade of CXCL10 protects mice from acute colitis and enhances crypt cell survival. Eur J Immunol (2002) 1.36
Localization of propionibacterium acnes in granulomas supports a possible etiologic link between sarcoidosis and the bacterium. Mod Pathol (2012) 1.27
eNOS deficiency predisposes podocytes to injury in diabetes. J Am Soc Nephrol (2012) 1.26
Retinoids regulate the repairing process of the podocytes in puromycin aminonucleoside-induced nephrotic rats. J Am Soc Nephrol (2003) 1.24
Contribution of nonproteolytically activated prorenin in glomeruli to hypertensive renal damage. J Am Soc Nephrol (2006) 1.21
A prospective evaluation of renal replacement therapy modality eligibility. Nephrol Dial Transplant (2008) 1.16
Rat nephrin modulates cell morphology via the adaptor protein Nck. Biochem Biophys Res Commun (2006) 1.15
Nephrin and podocin dissociate at the onset of proteinuria in experimental membranous nephropathy. Kidney Int (2005) 1.15
Role of the endoplasmic reticulum unfolded protein response in glomerular epithelial cell injury. J Biol Chem (2005) 1.14
Health-related quality of life and hemoglobin levels in chronic kidney disease patients. Clin J Am Soc Nephrol (2008) 1.14
Intrarenal injection of bone marrow-derived angiogenic cells reduces endothelial injury and mesangial cell activation in experimental glomerulonephritis. J Am Soc Nephrol (2005) 1.11
Frequent silencing of protocadherin 17, a candidate tumour suppressor for esophageal squamous cell carcinoma. Carcinogenesis (2010) 1.11
Induction of apoptosis by the Ste20-like kinase SLK, a germinal center kinase that activates apoptosis signal-regulating kinase and p38. J Biol Chem (2005) 1.11
Optimal colorectal cancer staging criteria in TNM classification. J Clin Oncol (2012) 1.11
Angiotensin II type 1 and type 2 receptors play opposite roles in regulating the barrier function of kidney glomerular capillary wall. Am J Pathol (2007) 1.10
Low-dose mTOR inhibition by rapamycin attenuates progression in anti-thy1-induced chronic glomerulosclerosis of the rat. Am J Physiol Renal Physiol (2007) 1.10
Curcumin ameliorates macrophage infiltration by inhibiting NF-κB activation and proinflammatory cytokines in streptozotocin induced-diabetic nephropathy. Nutr Metab (Lond) (2011) 1.10
Loss of the BMP antagonist USAG-1 ameliorates disease in a mouse model of the progressive hereditary kidney disease Alport syndrome. J Clin Invest (2010) 1.09
Multicenter study for optimal categorization of extramural tumor deposits for colorectal cancer staging. Ann Surg (2012) 1.09
Transforming growth factor-beta inhibits telomerase through SMAD3 and E2F transcription factors. Cell Signal (2007) 1.06
Angiotensin type 2 receptor antagonism confers renal protection in a rat model of progressive renal injury. J Am Soc Nephrol (2002) 1.06
Complement C5b-9 membrane attack complex increases expression of endoplasmic reticulum stress proteins in glomerular epithelial cells. J Biol Chem (2002) 1.04
Curcumin alleviates oxidative stress, inflammation, and renal fibrosis in remnant kidney through the Nrf2-keap1 pathway. Mol Nutr Food Res (2012) 1.04
Selective loss of podoplanin protein expression accompanies proteinuria and precedes alterations in podocyte morphology in a spontaneous proteinuric rat model. Am J Pathol (2008) 1.04
Prostaglandin E2 promotes cell survival of glomerular epithelial cells via the EP4 receptor. Am J Physiol Renal Physiol (2006) 1.04
MAGI-1 is a component of the glomerular slit diaphragm that is tightly associated with nephrin. Lab Invest (2005) 1.03
Dissociation of NEPH1 from nephrin is involved in development of a rat model of focal segmental glomerulosclerosis. Am J Physiol Renal Physiol (2008) 1.03
Reduction of NOTCH1 expression pertains to maturation abnormalities of keratinocytes in squamous neoplasms. Lab Invest (2012) 1.02
Identification of alternatively activated macrophages in new-onset paediatric and adult immunoglobulin A nephropathy: potential role in mesangial matrix expansion. Histopathology (2011) 1.02
Actual status of distribution and prognostic impact of extramural discontinuous cancer spread in colorectal cancer. J Clin Oncol (2011) 1.02
Activin induces hepatocyte cell growth arrest through induction of the cyclin-dependent kinase inhibitor p15INK4B and Sp1. Cell Signal (2004) 1.02
ARHGDIA: a novel gene implicated in nephrotic syndrome. J Med Genet (2013) 1.01
Tolvaptan, a selective oral vasopressin V2 receptor antagonist, ameliorates podocyte injury in puromycin aminonucleoside nephrotic rats. Clin Exp Nephrol (2009) 1.01
Rac1 contributes to actin organization in glomerular podocytes. Nephron Exp Nephrol (2009) 1.00
Kidney-targeted naked DNA transfer by retrograde renal vein injection in rats. Hum Gene Ther (2002) 1.00
A novel rat lipoxin A4 receptor that is conserved in structure and function. Br J Pharmacol (2003) 1.00
Active vitamin D and its analogue, 22-oxacalcitriol, ameliorate puromycin aminonucleoside-induced nephrosis in rats. Nephrol Dial Transplant (2009) 1.00
Down-regulation of keratin 4 and keratin 13 expression in oral squamous cell carcinoma and epithelial dysplasia: a clue for histopathogenesis. Histopathology (2011) 0.98
Enhancing cGMP in experimental progressive renal fibrosis: soluble guanylate cyclase stimulation vs. phosphodiesterase inhibition. Am J Physiol Renal Physiol (2005) 0.98
Contrasting effects of steroids and mizoribine on macrophage activation and glomerular lesions in rat thy-1 mesangial proliferative glomerulonephritis. Am J Nephrol (2010) 0.97
Role of Rho-GTPases in complement-mediated glomerular epithelial cell injury. Am J Physiol Renal Physiol (2007) 0.97
Blockade of interferon-gamma-inducible protein-10 attenuates chronic experimental colitis by blocking cellular trafficking and protecting intestinal epithelial cells. Pathol Int (2007) 0.96
Histological differences in new-onset IgA nephropathy between children and adults. Nephrol Dial Transplant (2006) 0.96
Lysosome is a primary organelle in B cell receptor-mediated apoptosis: an indispensable role of Syk in lysosomal function. Genes Cells (2005) 0.94
Glomerular epithelial cell injury associated with mutant alpha-actinin-4. Am J Physiol Renal Physiol (2009) 0.94
Modulation of nephrin in the diabetic kidney: association with systemic hypertension and increasing albuminuria. J Hypertens (2002) 0.94
ERK5 activation enhances mesangial cell viability and collagen matrix accumulation in rat progressive glomerulonephritis. Am J Physiol Renal Physiol (2009) 0.94
Activation of the extracellular signal-regulated kinase by complement C5b-9. Am J Physiol Renal Physiol (2005) 0.93
The mTOR inhibitor everolimus attenuates the time course of chronic anti-Thy1 nephritis in the rat. Nephron Exp Nephrol (2008) 0.93
Planar cell polarity pathway regulates nephrin endocytosis in developing podocytes. J Biol Chem (2013) 0.93
Nanofluidic redox cycling amplification for the selective detection of catechol. Anal Chem (2008) 0.93
Continuous, noninvasive monitoring of local microscopic inflammation using a genetically engineered cell-based biosensor. Lab Invest (2005) 0.93
Upregulation of EphA2 during in vivo and in vitro renal ischemia-reperfusion injury: role of Src kinases. Am J Physiol Renal Physiol (2006) 0.92
Characterization of perineural invasion as a component of colorectal cancer staging. Am J Surg Pathol (2013) 0.92
Activated macrophages down-regulate podocyte nephrin and podocin expression via stress-activated protein kinases. Biochem Biophys Res Commun (2008) 0.92
Induction of apoptosis by epigallocatechin-3-gallate in human lymphoblastoid B cells. Biochem Biophys Res Commun (2007) 0.91
Early treatment with olmesartan prevents juxtamedullary glomerular podocyte injury and the onset of microalbuminuria in type 2 diabetic rats. Am J Hypertens (2012) 0.91
Fractalkine expression and the recruitment of CX3CR1+ cells in the prolonged mesangial proliferative glomerulonephritis. Kidney Int (2002) 0.91
Chemically modified siRNA prolonged RNA interference in renal disease. Biochem Biophys Res Commun (2007) 0.91
Analysis of intestinal fibrosis in chronic colitis in mice induced by dextran sulfate sodium. Pathol Int (2011) 0.91
The sialoadhesin (CD169) expressing a macrophage subset in human proliferative glomerulonephritis. Nephrol Dial Transplant (2005) 0.91
Addition of the antioxidant probucol to angiotensin II type I receptor antagonist arrests progressive mesangioproliferative glomerulonephritis in the rat. J Am Soc Nephrol (2006) 0.90
Selective lymphocyte inhibition by FTY720 slows the progressive course of chronic anti-thy 1 glomerulosclerosis. Kidney Int (2004) 0.90
SM22alpha: the novel phenotype marker of injured glomerular epithelial cells in anti-glomerular basement membrane nephritis. Nephron Exp Nephrol (2007) 0.90
Actin cytoskeleton regulates extracellular matrix-dependent survival signals in glomerular epithelial cells. Am J Physiol Renal Physiol (2005) 0.90
Curcumin decreases renal triglyceride accumulation through AMPK-SREBP signaling pathway in streptozotocin-induced type 1 diabetic rats. J Nutr Biochem (2012) 0.90
Decreased expression of SOCS-3 mRNA in breast cancer with lymph node metastasis. Oncol Rep (2008) 0.90
Blockade of IP-10/CXCR3 promotes progressive renal fibrosis. Nephron Exp Nephrol (2007) 0.90
Real-time monitoring of mesangial cell-macrophage cross-talk using SEAP in vitro and ex vivo. Kidney Int (2005) 0.89
Neutralization of CXCL10 accelerates liver regeneration in carbon tetrachloride-induced acute liver injury. Med Mol Morphol (2007) 0.89
Retinoic acid receptor alpha and retinoid X receptor specific agonists reduce renal injury in established chronic glomerulonephritis of the rat. J Mol Med (Berl) (2004) 0.89
Extracellular matrix regulates glomerular epithelial cell survival and proliferation. Am J Physiol Renal Physiol (2003) 0.89
HPV infection in an HIV-positive patient with primary squamous cell carcinoma of rectum. Int J Clin Oncol (2009) 0.89
Multi-center survey regarding the management of anticoagulation and antiplatelet therapy for endoscopic procedures in Japan. J Gastroenterol Hepatol (2008) 0.89
p21-activated kinases regulate actin remodeling in glomerular podocytes. Am J Physiol Renal Physiol (2010) 0.88