Local and systemic B cell and Th1 responses induced following ocular mucosal delivery of multiple epitopes of herpes simplex virus type 1 glycoprotein D together with cytosine-phosphate-guanine adjuvant.

PubWeight™: 0.98‹?› | Rank: Top 15%

🔗 View Article (PMID 15603887)

Published in Vaccine on January 04, 2005

Authors

Anthony B Nesburn1, Thomas V Ramos, Xiaoming Zhu, Hanieh Asgarzadeh, Vu Nguyen, Lbachir BenMohamed

Author Affiliations

1: Laboratory of Cellular and Molecular Immunology, Department of Ophthalmology, College of Medicine, University of California at Irvine, Irvine, CA 92697-4375, USA.

Articles citing this

CpG DNA as a vaccine adjuvant. Expert Rev Vaccines (2011) 2.17

A genital tract peptide epitope vaccine targeting TLR-2 efficiently induces local and systemic CD8+ T cells and protects against herpes simplex virus type 2 challenge. Mucosal Immunol (2008) 1.16

Th-cytotoxic T-lymphocyte chimeric epitopes extended by Nepsilon-palmitoyl lysines induce herpes simplex virus type 1-specific effector CD8+ Tc1 responses and protect against ocular infection. J Virol (2005) 1.10

Of mice and not humans: how reliable are animal models for evaluation of herpes CD8(+)-T cell-epitopes-based immunotherapeutic vaccine candidates? Vaccine (2011) 1.07

New concepts in herpes simplex virus vaccine development: notes from the battlefield. Expert Rev Vaccines (2009) 1.07

A novel HLA (HLA-A*0201) transgenic rabbit model for preclinical evaluation of human CD8+ T cell epitope-based vaccines against ocular herpes. J Immunol (2010) 1.06

Functional Foxp3+ CD4+ CD25(Bright+) "natural" regulatory T cells are abundant in rabbit conjunctiva and suppress virus-specific CD4+ and CD8+ effector T cells during ocular herpes infection. J Virol (2007) 1.02

Nasolacrimal duct closure modulates ocular mucosal and systemic CD4(+) T-cell responses induced following topical ocular or intranasal immunization. Clin Vaccine Immunol (2010) 0.94

Mucosal herpes immunity and immunopathology to ocular and genital herpes simplex virus infections. Clin Dev Immunol (2012) 0.93

Gender-dependent HLA-DR-restricted epitopes identified from herpes simplex virus type 1 glycoprotein D. Clin Vaccine Immunol (2008) 0.92

Immunodominant "asymptomatic" herpes simplex virus 1 and 2 protein antigens identified by probing whole-ORFome microarrays with serum antibodies from seropositive asymptomatic versus symptomatic individuals. J Virol (2012) 0.90

Associations of HLA-A, HLA-B and HLA-C alleles frequency with prevalence of herpes simplex virus infections and diseases across global populations: implication for the development of an universal CD8+ T-cell epitope-based vaccine. Hum Immunol (2014) 0.86

Asymptomatic memory CD8+ T cells: from development and regulation to consideration for human vaccines and immunotherapeutics. Hum Vaccin Immunother (2014) 0.85

The challenges and opportunities for the development of a T-cell epitope-based herpes simplex vaccine. Vaccine (2014) 0.84

Therapeutic immunization with a mixture of herpes simplex virus 1 glycoprotein D-derived “asymptomatic” human CD8+ T-cell epitopes decreases spontaneous ocular shedding in latently infected HLA transgenic rabbits: association with low frequency of local PD-1+ TIM-3+ CD8+ exhausted T cells. J Virol (2015) 0.84

A Herpes Simplex Virus Type 1 Human Asymptomatic CD8+ T-Cell Epitopes-Based Vaccine Protects Against Ocular Herpes in a "Humanized" HLA Transgenic Rabbit Model. Invest Ophthalmol Vis Sci (2015) 0.81

The Herpes Simplex Virus Latency-Associated Transcript Gene Is Associated with a Broader Repertoire of Virus-Specific Exhausted CD8+ T Cells Retained within the Trigeminal Ganglia of Latently Infected HLA Transgenic Rabbits. J Virol (2016) 0.77

Self-assembled or mixed peptide amphiphile micelles from Herpes simplex virus glycoproteins as potential immunomodulatory treatment. Int J Nanomedicine (2014) 0.76

Mucosally delivered peptides prime strong immunity in HLA-A2.1 transgenic rabbits. Vaccine (2010) 0.76

A Probiotic Adjuvant Lactobacillus rhamnosus Enhances Specific Immune Responses after Ocular Mucosal Immunization with Chlamydial Polymorphic Membrane Protein C. PLoS One (2016) 0.75

Age-related Defects in Ocular and Nasal Mucosal Immune System and the Immunopathology of Dry Eye Disease. Ocul Immunol Inflamm (2014) 0.75

Articles by these authors

A surfactant protein C precursor protein BRICHOS domain mutation causes endoplasmic reticulum stress, proteasome dysfunction, and caspase 3 activation. Am J Respir Cell Mol Biol (2005) 1.90

Reduced-intensity conditioning with combined haploidentical and cord blood transplantation results in rapid engraftment, low GVHD, and durable remissions. Blood (2011) 1.55

Structure of the Plasmodium falciparum circumsporozoite protein, a leading malaria vaccine candidate. J Biol Chem (2009) 1.41

Autocitrullination of human peptidyl arginine deiminase type 4 regulates protein citrullination during cell activation. Arthritis Rheum (2010) 1.39

A novel herpes simplex virus type 1 transcript (AL-RNA) antisense to the 5' end of the latency-associated transcript produces a protein in infected rabbits. J Virol (2002) 1.30

A fully synthetic therapeutic vaccine candidate targeting carcinoma-associated Tn carbohydrate antigen induces tumor-specific antibodies in nonhuman primates. Cancer Res (2004) 1.26

HLA-A*0201-restricted CD8+ cytotoxic T lymphocyte epitopes identified from herpes simplex virus glycoprotein D. J Immunol (2008) 1.24

The role of LAT in increased CD8+ T cell exhaustion in trigeminal ganglia of mice latently infected with herpes simplex virus 1. J Virol (2011) 1.18

Lipopeptide epitopes extended by an Nepsilon-palmitoyl-lysine moiety increase uptake and maturation of dendritic cells through a Toll-like receptor-2 pathway and trigger a Th1-dependent protective immunity. Eur J Immunol (2004) 1.14

The herpes simplex virus type 1 latency-associated transcript can protect neuron-derived C1300 and Neuro2A cells from granzyme B-induced apoptosis and CD8 T-cell killing. J Virol (2010) 1.12

Th-cytotoxic T-lymphocyte chimeric epitopes extended by Nepsilon-palmitoyl lysines induce herpes simplex virus type 1-specific effector CD8+ Tc1 responses and protect against ocular infection. J Virol (2005) 1.10

The herpes simplex virus 1 latency-associated transcript promotes functional exhaustion of virus-specific CD8+ T cells in latently infected trigeminal ganglia: a novel immune evasion mechanism. J Virol (2011) 1.09

Gold and iron oxide hybrid nanocomposite materials. Chem Soc Rev (2011) 1.08

Of mice and not humans: how reliable are animal models for evaluation of herpes CD8(+)-T cell-epitopes-based immunotherapeutic vaccine candidates? Vaccine (2011) 1.07

Preparation and biologic evaluation of a novel radioiodinated benzylpiperazine, 123I-MEL037, for malignant melanoma. J Nucl Med (2007) 1.07

New concepts in herpes simplex virus vaccine development: notes from the battlefield. Expert Rev Vaccines (2009) 1.07

Development of a Pfs25-EPA malaria transmission blocking vaccine as a chemically conjugated nanoparticle. Vaccine (2013) 1.07

Protective immunity to genital herpes simplex virus type 1 and type 2 provided by self-adjuvanting lipopeptides that drive dendritic cell maturation and elicit a polarized Th1 immune response. Viral Immunol (2006) 1.06

Level of herpes simplex virus type 1 latency correlates with severity of corneal scarring and exhaustion of CD8+ T cells in trigeminal ganglia of latently infected mice. J Virol (2008) 1.06

A novel HLA (HLA-A*0201) transgenic rabbit model for preclinical evaluation of human CD8+ T cell epitope-based vaccines against ocular herpes. J Immunol (2010) 1.06

Identification and characterization of the Plasmodium yoelii PyP140/RON4 protein, an orthologue of Toxoplasma gondii RON4, whose cysteine-rich domain does not protect against lethal parasite challenge infection. Infect Immun (2008) 1.05

Overcoming allelic specificity by immunization with five allelic forms of Plasmodium falciparum apical membrane antigen 1. Infect Immun (2013) 1.05

Stable cell lines expressing high levels of the herpes simplex virus type 1 LAT are refractory to caspase 3 activation and DNA laddering following cold shock induced apoptosis. Virology (2007) 1.04

Asymptomatic human CD4+ cytotoxic T-cell epitopes identified from herpes simplex virus glycoprotein B. J Virol (2008) 1.04

Variations of microRNAs in human placentas and plasma from preeclamptic pregnancy. Hypertension (2014) 1.04

The locus encompassing the latency-associated transcript of herpes simplex virus type 1 interferes with and delays interferon expression in productively infected neuroblastoma cells and trigeminal Ganglia of acutely infected mice. J Virol (2005) 1.04

Towards a self-adjuvanting multivalent B and T cell epitope containing synthetic glycolipopeptide cancer vaccine. ChemMedChem (2008) 1.03

Brown adipose tissue transplantation improves whole-body energy metabolism. Cell Res (2013) 1.03

Functional Foxp3+ CD4+ CD25(Bright+) "natural" regulatory T cells are abundant in rabbit conjunctiva and suppress virus-specific CD4+ and CD8+ effector T cells during ocular herpes infection. J Virol (2007) 1.02

The flotillins are integral membrane proteins in lipid rafts that contain TCR-associated signaling components: implications for T-cell activation. Clin Immunol (2003) 1.00

Antitumor activity of a self-adjuvanting glyco-lipopeptide vaccine bearing B cell, CD4+ and CD8+ T cell epitopes. Cancer Immunol Immunother (2008) 1.00

The role of a glycoprotein K (gK) CD8+ T-cell epitope of herpes simplex virus on virus replication and pathogenicity. Invest Ophthalmol Vis Sci (2009) 0.99

Protective immunity against ocular herpes infection and disease induced by highly immunogenic self-adjuvanting glycoprotein D lipopeptide vaccines. Invest Ophthalmol Vis Sci (2007) 0.99

Linear and branched glyco-lipopeptide vaccines follow distinct cross-presentation pathways and generate different magnitudes of antitumor immunity. PLoS One (2010) 0.97

Engagement of TLR2 reverses the suppressor function of conjunctiva CD4+CD25+ regulatory T cells and promotes herpes simplex virus epitope-specific CD4+CD25- effector T cell responses. Invest Ophthalmol Vis Sci (2011) 0.96

Topical/mucosal delivery of sub-unit vaccines that stimulate the ocular mucosal immune system. Ocul Surf (2006) 0.95

Asymptomatic HLA-A*02:01-restricted epitopes from herpes simplex virus glycoprotein B preferentially recall polyfunctional CD8+ T cells from seropositive asymptomatic individuals and protect HLA transgenic mice against ocular herpes. J Immunol (2013) 0.95

Nasolacrimal duct closure modulates ocular mucosal and systemic CD4(+) T-cell responses induced following topical ocular or intranasal immunization. Clin Vaccine Immunol (2010) 0.94

Developing an asymptomatic mucosal herpes vaccine: the present and the future. Future Microbiol (2010) 0.92

Discovery of potential diagnostic and vaccine antigens in herpes simplex virus 1 and 2 by proteome-wide antibody profiling. J Virol (2012) 0.92

Phase I-II study of clofarabine-melphalan-alemtuzumab conditioning for allogeneic hematopoietic cell transplantation. Biol Blood Marrow Transplant (2011) 0.92

Gender-dependent HLA-DR-restricted epitopes identified from herpes simplex virus type 1 glycoprotein D. Clin Vaccine Immunol (2008) 0.92

Immunodominant "asymptomatic" herpes simplex virus 1 and 2 protein antigens identified by probing whole-ORFome microarrays with serum antibodies from seropositive asymptomatic versus symptomatic individuals. J Virol (2012) 0.90

Introducing point mutations into the ATGs of the putative open reading frames of the HSV-1 gene encoding the latency associated transcript (LAT) reduces its anti-apoptosis activity. Microb Pathog (2007) 0.89

Prevalence of diabetes and predictions of its risks using anthropometric measures in southwest rural areas of China. BMC Public Health (2012) 0.88

HRS inhibits EGF receptor signaling in the RT4 rat schwannoma cell line. Biochem Biophys Res Commun (2005) 0.88

MRI findings in the painful poststroke shoulder. Stroke (2008) 0.87

Future viral vectors for the delivery of asymptomatic herpes epitope-based immunotherapeutic vaccines. Future Virol (2010) 0.86

Proteomic analysis of metabolic, cytoskeletal and stress response proteins in human heart failure. J Cell Mol Med (2012) 0.86

A cancer therapeutic vaccine based on clustered Tn-antigen mimetics induces strong antibody-mediated protective immunity. Angew Chem Int Ed Engl (2014) 0.85

Detection of apoptotic cell death in the thymus of dexamethasone treated rats using [123I]annexin V and in situ oligonucleotide ligation. J Mol Histol (2007) 0.85

CD11c controls herpes simplex virus 1 responses to limit virus replication during primary infection. J Virol (2011) 0.84

Therapeutic immunization with a mixture of herpes simplex virus 1 glycoprotein D-derived “asymptomatic” human CD8+ T-cell epitopes decreases spontaneous ocular shedding in latently infected HLA transgenic rabbits: association with low frequency of local PD-1+ TIM-3+ CD8+ exhausted T cells. J Virol (2015) 0.84

A herpes simplex virus type 1 mutant disrupted for microRNA H2 with increased neurovirulence and rate of reactivation. J Neurovirol (2015) 0.83

Immunogenicity of self-associated aggregates and chemically cross-linked conjugates of the 42 kDa Plasmodium falciparum merozoite surface protein-1. PLoS One (2012) 0.83

Interferon-γ, a valuable surrogate marker of Plasmodium falciparum pre-erythrocytic stages protective immunity. Malar J (2011) 0.83

Characterization of Erysipelothrix rhusiopathiae strains isolated from acute swine erysipelas outbreaks in Eastern China. J Vet Med Sci (2015) 0.83

Photocytotoxicity and magnetic relaxivity responses of dual-porous γ-Fe2O3@meso-SiO2 microspheres. ACS Appl Mater Interfaces (2012) 0.82

Immune reconstitution after combined haploidentical and umbilical cord blood transplant. Leuk Lymphoma (2013) 0.82

Recent advances in multivalent self adjuvanting glycolipopeptide vaccine strategies against breast cancer. Arch Immunol Ther Exp (Warsz) (2009) 0.82

Improved yield of recombinant merozoite Surface protein 3 (MSP3) from Pichia pastoris using chemically defined media. Biotechnol Bioeng (2005) 0.81

Estrogenic effect of ginsenoside Rg1 on APP processing in post-menopausal platelets. Platelets (2012) 0.81

[Melanotic oncocytic metaplasia of the nasopharynx]. Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi (2005) 0.80

Comparison of Cannabinoid CB(1) Receptor Binding in Adolescent and Adult Rats: A Positron Emission Tomography Study Using [F]MK-9470. Int J Mol Imaging (2011) 0.80

Differences in the metabolic status of healthy adults with and without active brown adipose tissue. Wien Klin Wochenschr (2013) 0.80

Fatal CMV pneumonitis in a lymphoma patient treated with rituximab. Am J Hematol (2009) 0.80

HIV-1 infection impairs HSV-specific CD4(+) and CD8(+) T-cell response by reducing Th1 cytokines and CCR5 ligand secretion. J Acquir Immune Defic Syndr (2011) 0.79

Altered expression of interleukin-18 in the ectopic and eutopic endometrium of women with endometriosis. J Reprod Immunol (2006) 0.79

Influence of related donor age on outcomes after peripheral blood stem cell transplantation. Cytotherapy (2012) 0.79

Immunity to ocular and genital herpes simplex viruses infections. Clin Dev Immunol (2012) 0.79

Changes in serum IGF-1 level and tumor VEGF expression in mice with colorectal cancer under hyperglycemic conditions. Mol Med Rep (2013) 0.79

Rapid cortico-limbic alterations in AMPA receptor densities after administration of PCP: implications for schizophrenia. J Chem Neuroanat (2008) 0.78

Concentration of mammalian genomic DNA using two-phase aqueous micellar systems. Biotechnol Bioeng (2009) 0.78

Therapeutic Drug Monitoring and Clinical Outcomes in Immune Mediated Diseases: The Missing Link. Inflamm Bowel Dis (2016) 0.77

CD8+ lymphoma in a patient with human immunodeficiency virus. Arch Dermatol (2005) 0.77

Effect of replacement of fish meal by meat and bone meal and poultry by-product meal in diets on the growth and immune response of Macrobrachium nipponense. Fish Shellfish Immunol (2004) 0.77

Differential expression of estradiol and estrogen receptor α in severe preeclamptic pregnancies compared with normal pregnancies. Mol Med Rep (2013) 0.76

Perioperative management of the post-gastric-bypass patient presenting for body contour surgery. Clin Plast Surg (2004) 0.76

β-sitosterol inhibits high cholesterol-induced platelet β-amyloid release. J Bioenerg Biomembr (2011) 0.76

Confocal Microscopic Analysis of a Rabbit Eye Model of High-Incidence Recurrent Herpes Stromal Keratitis. Cornea (2016) 0.75

Cytokine profiling in patients with VCP-associated disease. Clin Transl Sci (2013) 0.75

Rotational Fourier tracking of diffusing polygons. Phys Rev E Stat Nonlin Soft Matter Phys (2011) 0.75

Scalable alignment and transfer of nanowires in a Spinning Langmuir Film. Nanoscale (2014) 0.75

Recurrent Median Nerve Injury in a Weight Lifter. Am J Phys Med Rehabil (2017) 0.75

Reproductive outcome following resectoscope metroplasty in women having a complete uterine septum with double cervix and vagina. Int J Gynaecol Obstet (2008) 0.75

The photodimerization of a cinnamoyl moiety derivative in dilute solution based on the intramolecular chain interaction of gemini surfactant. J Phys Chem B (2008) 0.75

Response and recovery of hybrid sturgeon from subchronic oral administration of cyanobacteria. Environ Toxicol (2011) 0.75

[Construction and expression of eukaryotic expression plasmid pIRES-neo-HBAg carrying HBV fusion antigen gene]. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi (2013) 0.75

Abstract 44: components separation for abdominal wall reconstruction: the pitt experience, a review of 605 cases. Plast Reconstr Surg (2014) 0.75

Treatment of rheumatic arthritis with Jiang Chen pian in 114 cases. J Tradit Chin Med (2002) 0.75

Breast-feeding, dietary intakes and their associations with subclinical vitamin A deficiency in children in Anhui Province, China. Public Health Nutr (2007) 0.75

Induced respiratory system modeling by high frequency chest compression using lumped system identification method. Conf Proc IEEE Eng Med Biol Soc (2009) 0.75

[Construction and application of the replicon DNA recombinant plasmid pSVK-luc]. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi (2013) 0.75

[Expression of human tumor necrosis factor receptor-Fc fusion protein and characterization of its biological activity]. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi (2014) 0.75

Effects of dietary cyanobacteria of two different sources on growth and recovery of hybrid tilapia (Oreochromis niloticus x O. aureus). Toxicon (2009) 0.75

[Preliminary investigation of intramural lateral spread distance in pull-through conformal resection of low rectal cancer]. Zhonghua Wei Chang Wai Ke Za Zhi (2016) 0.75