PubRank

A Brian Jones

Author PubWeight™ 13.21‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Benzoyl 2-methyl indoles as selective PPARgamma modulators. Bioorg Med Chem Lett 2005 1.17
2 Functional properties of the high-affinity TRPV1 (VR1) vanilloid receptor antagonist (4-hydroxy-5-iodo-3-methoxyphenylacetate ester) iodo-resiniferatoxin. J Pharmacol Exp Ther 2002 1.16
3 A potent synthetic LXR agonist is more effective than cholesterol loading at inducing ABCA1 mRNA and stimulating cholesterol efflux. J Biol Chem 2002 1.13
4 A novel series of potent gamma-secretase inhibitors based on a benzobicyclo[4.2.1]nonane core. Bioorg Med Chem Lett 2005 0.98
5 N',2-diphenylquinoline-4-carbohydrazide based NK3 receptor antagonists. Bioorg Med Chem Lett 2006 0.89
6 Regulation of insulin signal transduction pathway by a small-molecule insulin receptor activator. Biochem J 2002 0.86
7 Selective PPARgamma modulators with improved pharmacological profiles. Bioorg Med Chem Lett 2005 0.85
8 Design and synthesis of alpha-aryloxyphenylacetic acid derivatives: a novel class of PPARalpha/gamma dual agonists with potent antihyperglycemic and lipid modulating activity. J Med Chem 2005 0.80
9 Discovery of novel 6,6-heterocycles as transient receptor potential vanilloid (TRPV1) antagonists. J Med Chem 2010 0.80
10 (2R)-2-ethylchromane-2-carboxylic acids: discovery of novel PPARalpha/gamma dual agonists as antihyperglycemic and hypolipidemic agents. J Med Chem 2004 0.79
11 Discovery and development of dimeric podocarpic acid leads as potent agonists of liver X receptor with HDL cholesterol raising activity in mice and hamsters. Bioorg Med Chem Lett 2005 0.78
12 NK1 antagonists based on seven membered lactam scaffolds. Bioorg Med Chem Lett 2006 0.77
13 Discovery of a novel series of peroxisome proliferator-activated receptor alpha/gamma dual agonists for the treatment of type 2 diabetes and dyslipidemia. J Med Chem 2005 0.76
14 N',2-diphenylquinoline-4-carbohydrazide based NK3 receptor antagonists II. Bioorg Med Chem Lett 2006 0.76
15 O-arylmandelic acids as highly selective human PPAR alpha/gamma agonists. Bioorg Med Chem Lett 2003 0.76
16 Amphipathic 3-phenyl-7-propylbenzisoxazoles; human pPaR gamma, delta and alpha agonists. Bioorg Med Chem Lett 2003 0.75