Published in Brief Bioinform on December 01, 2004
An integrative top-down and bottom-up qualitative model construction framework for exploration of biochemical systems. Soft comput (2015) 0.78
Mining kidney toxicogenomic data by using gene co-expression modules. BMC Genomics (2016) 0.75
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. Nat Genet (2010) 23.08
Hundreds of variants clustered in genomic loci and biological pathways affect human height. Nature (2010) 20.01
New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk. Nat Genet (2010) 17.89
Genome-wide association analysis identifies 20 loci that influence adult height. Nat Genet (2008) 16.92
Common variants near MC4R are associated with fat mass, weight and risk of obesity. Nat Genet (2008) 15.94
Genes mirror geography within Europe. Nature (2008) 14.23
Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. Nature (2011) 13.25
Genome-wide association study identifies eight loci associated with blood pressure. Nat Genet (2009) 12.44
Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution. Nat Genet (2010) 7.94
Genetic variation in IL28B is associated with chronic hepatitis C and treatment failure: a genome-wide association study. Gastroenterology (2010) 7.86
The evolution of gene expression levels in mammalian organs. Nature (2011) 7.16
Revealing modular organization in the yeast transcriptional network. Nat Genet (2002) 6.73
Meta-analysis of 28,141 individuals identifies common variants within five new loci that influence uric acid concentrations. PLoS Genet (2009) 4.97
Population-based genome-wide association studies reveal six loci influencing plasma levels of liver enzymes. Am J Hum Genet (2008) 4.69
Physical activity attenuates the influence of FTO variants on obesity risk: a meta-analysis of 218,166 adults and 19,268 children. PLoS Med (2011) 3.94
Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure. Nat Genet (2011) 3.40
Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies. Nat Genet (2010) 3.37
Defining transcription modules using large-scale gene expression data. Bioinformatics (2004) 3.33
Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals. PLoS Genet (2012) 3.21
Rewiring of the yeast transcriptional network through the evolution of motif usage. Science (2005) 3.10
CUBN is a gene locus for albuminuria. J Am Soc Nephrol (2011) 2.70
Mirror extreme BMI phenotypes associated with gene dosage at the chromosome 16p11.2 locus. Nature (2011) 2.59
Comparative gene expression analysis by differential clustering approach: application to the Candida albicans transcription program. PLoS Genet (2005) 2.36
Comparative genome hybridization reveals widespread aneuploidy in Candida albicans laboratory strains. Mol Microbiol (2005) 2.16
SIRT1 activates MAO-A in the brain to mediate anxiety and exploratory drive. Cell (2011) 1.86
A genome-wide association search for type 2 diabetes genes in African Americans. PLoS One (2012) 1.72
Genome-wide association and functional follow-up reveals new loci for kidney function. PLoS Genet (2012) 1.68
Genome-wide association study identifies new HLA class II haplotypes strongly protective against narcolepsy. Nat Genet (2010) 1.67
FastEpistasis: a high performance computing solution for quantitative trait epistasis. Bioinformatics (2010) 1.58
Sensitivity of genome-wide-association signals to phenotyping strategy: the PROP-TAS2R38 taste association as a benchmark. PLoS One (2011) 1.56
A modular approach for integrative analysis of large-scale gene-expression and drug-response data. Nat Biotechnol (2008) 1.55
A genome-wide association study of early menopause and the combined impact of identified variants. Hum Mol Genet (2013) 1.50
The evolving doublecortin (DCX) superfamily. BMC Genomics (2006) 1.29
Discovery and fine mapping of serum protein loci through transethnic meta-analysis. Am J Hum Genet (2012) 1.29
Contribution of 20 single nucleotide polymorphisms of 13 genes to dyslipidemia associated with antiretroviral therapy. Pharmacogenet Genomics (2007) 1.25
Genome-wide meta-analysis for serum calcium identifies significantly associated SNPs near the calcium-sensing receptor (CASR) gene. PLoS Genet (2010) 1.25
Dpp signaling activity requires Pentagone to scale with tissue size in the growing Drosophila wing imaginal disc. PLoS Biol (2011) 1.24
Integration of genome-wide association studies with biological knowledge identifies six novel genes related to kidney function. Hum Mol Genet (2012) 1.14
Common and divergent roles for members of the mouse DCX superfamily. Cell Cycle (2006) 1.13
Re-examining the stability of the Bicoid morphogen gradient. Cell (2008) 1.10
Correcting for the bias due to expression specificity improves the estimation of constrained evolution of expression between mouse and human. Bioinformatics (2012) 1.10
Precision and scaling in morphogen gradient read-out. Mol Syst Biol (2010) 1.05
Formation of the long range Dpp morphogen gradient. PLoS Biol (2011) 1.03
Methods for testing association between uncertain genotypes and quantitative traits. Biostatistics (2010) 1.02
Meta-analysis of genome-wide association studies identifies six new Loci for serum calcium concentrations. PLoS Genet (2013) 1.02
Novel method to estimate the phenotypic variation explained by genome-wide association studies reveals large fraction of the missing heritability. Genet Epidemiol (2011) 1.02
Cardiovascular response to beta-adrenergic blockade or activation in 23 inbred mouse strains. PLoS One (2009) 0.99
Nuclear phytochrome A signaling promotes phototropism in Arabidopsis. Plant Cell (2012) 0.97
The hourglass and the early conservation models--co-existing patterns of developmental constraints in vertebrates. PLoS Genet (2013) 0.97
Phytochrome Kinase Substrate 4 is phosphorylated by the phototropin 1 photoreceptor. EMBO J (2012) 0.95
Light intensity modulates the regulatory network of the shade avoidance response in Arabidopsis. Proc Natl Acad Sci U S A (2014) 0.95
Using transcription modules to identify expression clusters perturbed in Williams-Beuren syndrome. PLoS Comput Biol (2011) 0.92
Modular analysis of gene expression data with R. Bioinformatics (2010) 0.92
DNA mismatch repair gene MSH6 implicated in determining age at natural menopause. Hum Mol Genet (2013) 0.88
Genome-wide association study identifies two loci strongly affecting transferrin glycosylation. Hum Mol Genet (2011) 0.87
No interaction between alcohol consumption and HDL-related genes on HDL cholesterol levels. Atherosclerosis (2010) 0.87
Identification and validation of copy number variants using SNP genotyping arrays from a large clinical cohort. BMC Genomics (2012) 0.86
No interactions between previously associated 2-hour glucose gene variants and physical activity or BMI on 2-hour glucose levels. Diabetes (2012) 0.86
Cell-mediated cytotoxicity in rainbow trout, Oncorhynchus mykiss, infected with viral haemorrhagic septicaemia virus. Fish Shellfish Immunol (2006) 0.85
EuroDia: a beta-cell gene expression resource. Database (Oxford) (2010) 0.84
Aging of myelinating glial cells predominantly affects lipid metabolism and immune response pathways. Glia (2012) 0.84
Defining the site of light perception and initiation of phototropism in Arabidopsis. Curr Biol (2013) 0.83
GWAS of human bitter taste perception identifies new loci and reveals additional complexity of bitter taste genetics. Hum Mol Genet (2013) 0.82
Common variants in Mendelian kidney disease genes and their association with renal function. J Am Soc Nephrol (2013) 0.82
Global transcriptional programs in peripheral nerve endoneurium and DRG are resistant to the onset of type 1 diabetic neuropathy in Ins2 mice. PLoS One (2010) 0.81
Corrigendum: Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses. Nat Genet (2016) 0.81
Investigations on the ORF 167L of lymphocystis disease virus (Iridoviridae). Virus Genes (2004) 0.80
Variant within the promoter region of the CHRNA3 gene associated with FTN dependence is not related to self-reported willingness to quit smoking. Nicotine Tob Res (2011) 0.79
Comparison of strategies to detect epistasis from eQTL data. PLoS One (2011) 0.79
Carriers of the fragile X mental retardation 1 (FMR1) premutation allele present with increased levels of cytokine IL-10. J Neuroinflammation (2012) 0.79
Caffeine intake and CYP1A2 variants associated with high caffeine intake protect non-smokers from hypertension. Hum Mol Genet (2012) 0.79
Comparative modular analysis of gene expression in vertebrate organs. BMC Genomics (2012) 0.78
Manipulating the sensitivity of signal-induced repression: quantification and consequences of altered brinker gradients. PLoS One (2013) 0.78
Association of ABCB1 genetic variants with renal function in Africans and in Caucasians. BMC Med Genomics (2008) 0.78
Mapping genetic variants associated with beta-adrenergic responses in inbred mice. PLoS One (2012) 0.78
ExpressionView--an interactive viewer for modules identified in gene expression data. Bioinformatics (2010) 0.78
Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study. PLoS Genet (2016) 0.75
Genetic polymorphisms of the main transcription factors for adiponectin gene promoter in regulation of adiponectin levels: association analysis in three European cohorts. PLoS One (2012) 0.75
Correction: Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults. PLoS Genet (2017) 0.75
Corrigendum: Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses. Nat Genet (2016) 0.75