Published in Biochem Pharmacol on March 17, 1992
Role of HIF-1alpha in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis. Nature (1998) 11.61
Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours. Nature (1996) 10.14
Nucleotide sequence of the L-arabinose regulatory region of Escherichia coli K12. J Biol Chem (1978) 2.88
Thyroid-stimulating immunoglobulins in Graves' disease. Lancet (1974) 2.84
Carbimazole and the autoimmune response in Graves' disease. N Engl J Med (1980) 2.62
Relation of thyroid-stimulating immunoglobulins to thyroid function and effects of surgery, radioiodine, and antithyroid drugs. Lancet (1975) 2.57
Myocyte apoptosis during acute myocardial infarction in the mouse localizes to hypoxic regions but occurs independently of p53. J Clin Invest (1997) 2.31
[18F]-EF5, a marker for PET detection of hypoxia: synthesis of precursor and a new fluorination procedure. Appl Radiat Isot (2001) 2.08
Detection of hypoxic cells by monoclonal antibody recognizing 2-nitroimidazole adducts. Cancer Res (1993) 1.97
CDtool-an integrated software package for circular dichroism spectroscopic data processing, analysis, and archiving. Anal Biochem (2004) 1.96
Chronic lymphocytic leukemic cells exhibit apoptotic signaling via TRAIL-R1. Cell Death Differ (2005) 1.90
Dermoid cyst in the floor of the mouth. Review of the literature and case reports. Oral Surg Oral Med Oral Pathol (1994) 1.83
Anaphylaxis to the chlorhexidine component of Instillagel: a case series. Br J Anaesth (2008) 1.82
An enzyme-linked immunoassay for thyroid microsomal antibodies. J Immunol Methods (1982) 1.79
Potent and selective inhibition of human cathepsin K leads to inhibition of bone resorption in vivo in a nonhuman primate. J Bone Miner Res (2001) 1.76
Histology by magnetic resonance microscopy. Magn Reson Q (1993) 1.71
Inhibition of distal lung morphogenesis in Nkx2.1(-/-) embryos. Dev Dyn (2000) 1.67
Calibration of oxygen-dependent quenching of the phosphorescence of Pd-meso-tetra (4-carboxyphenyl) porphine: a phosphor with general application for measuring oxygen concentration in biological systems. Anal Biochem (1996) 1.66
Alteration in connexin 43 gap junction gene dosage impairs conotruncal heart development. Dev Biol (1998) 1.64
SB 239063, a second-generation p38 mitogen-activated protein kinase inhibitor, reduces brain injury and neurological deficits in cerebral focal ischemia. J Pharmacol Exp Ther (2001) 1.54
Detection of hypoxia in human squamous cell carcinoma by EF5 binding. Cancer Res (2000) 1.53
Thyroid-autoantibody synthesis by Hashimoto thyroid lymphocytes. Lancet (1979) 1.52
Immunoprecipitation assay for autoantibodies to steroid 21-hydroxylase in autoimmune adrenal diseases. Clin Chem (1995) 1.51
Noninvasive imaging of tumor hypoxia in rats using the 2-nitroimidazole 18F-EF5. Eur J Nucl Med Mol Imaging (2002) 1.51
Adaptation of chondrocytes to low oxygen tension: relationship between hypoxia and cellular metabolism. J Cell Physiol (1996) 1.49
Cloning of a human autoimmune response: preparation and sequencing of a human anti-thyroglobulin autoantibody using a combinatorial approach. Autoimmunity (1992) 1.47
Lymphocyte and monocyte subset changes during cardiopulmonary bypass: effects of aging and gender. J Lab Clin Med (1997) 1.46
Inhibition of p38 mitogen-activated protein kinase provides neuroprotection in cerebral focal ischemia. Med Res Rev (2001) 1.43
An improved radioreceptor assay for TSH receptor antibodies. Clin Endocrinol (Oxf) (1982) 1.42
Biomechanical evaluation of new fixation devices for mandibular angle fractures. Int J Oral Maxillofac Surg (1997) 1.41
Blockade of C5a and C5b-9 generation inhibits leukocyte and platelet activation during extracorporeal circulation. J Clin Invest (1995) 1.40
The importance of sodium pyruvate in assessing damage produced by hydrogen peroxide. Free Radic Biol Med (1997) 1.40
Complications of obstetric regional analgesia: how much information is enough? Int J Obstet Anesth (2004) 1.39
Increase of surface Ia-like antigen expression on human monocytes independent of antigenic stimuli. J Immunol (1981) 1.39
Dynamics of leukocyte-platelet adhesion in whole blood. Blood (1991) 1.38
Cardiopulmonary bypass induces leukocyte-platelet adhesion. Blood (1992) 1.36
Enterococcal superinfection and colonization with aztreonam therapy. Antimicrob Agents Chemother (1984) 1.35
Antagonizing the parathyroid calcium receptor stimulates parathyroid hormone secretion and bone formation in osteopenic rats. J Clin Invest (2000) 1.34
Thyroid autoantibody synthesis by cultures of thyroid and peripheral blood lymphocytes. I. Lymphocyte markers and response to pokeweed mitogen. Clin Exp Immunol (1983) 1.34
Cytomegalovirus antigenemia: clinical correlations in transplant recipients and in persons with AIDS. J Clin Microbiol (1993) 1.33
Binding of 3H-misonidazole to solid human tumors as a measure of tumor hypoxia. Int J Radiat Oncol Biol Phys (1986) 1.32
The interaction of the long-acting thyroid stimulator (LATS) with thyroid tissue in vitro. J Endocrinol (1970) 1.30
Prediction of relapse in hyperthyroid Graves' disease. Lancet (1980) 1.27
Mucosal tolerance and suppression of collagen-induced arthritis (CIA) induced by nasal inhalation of synthetic peptide 184-198 of bovine type II collagen (CII) expressing a dominant T cell epitope. Clin Exp Immunol (1996) 1.27
Measurement of thyrotropin receptor antibodies. Methods Enzymol (1981) 1.26
Importance of thiols in the reductive binding of 2-nitroimidazoles to macromolecules. Biochem Pharmacol (1990) 1.26
Bronchial tree penetration of antibiotics. Chest (1983) 1.22
Hypoxic heterogeneity in human tumors: EF5 binding, vasculature, necrosis, and proliferation. Am J Clin Oncol (2001) 1.22
Thyroid stimulators in health and disease. Clin Endocrinol (Oxf) (1975) 1.21
A novel technique for measuring human tissue pO2 at the cellular level. Br J Cancer (1986) 1.21
Highly sensitive assays of autoantibodies to thyroglobulin and to thyroid peroxidase. Clin Chem (1989) 1.20
Lymphocyte adhesion-dependent calcium signaling in human endothelial cells. J Cell Biol (1995) 1.20
Direct relationship between radiobiological hypoxia in tumors and monoclonal antibody detection of EF5 cellular adducts. Int J Cancer (1996) 1.20
Histone deacetylase inhibitors potentiate TNF-related apoptosis-inducing ligand (TRAIL)-induced apoptosis in lymphoid malignancies. Cell Death Differ (2004) 1.20
Activated and unactivated platelet adhesion to monocytes and neutrophils. Blood (1991) 1.20
Phenotype of recovering lymphoid cell populations after marrow transplantation. J Exp Med (1985) 1.20
Chemical depletion of glutathione in vivo. Methods Enzymol (1981) 1.20
Energy metabolism and T-cell-mediated cytolysis. I. Synergism between inhibitors of respiration and glycolysis. J Exp Med (1977) 1.19
Fluorescence immunohistochemical detection of hypoxic cells in spheroids and tumours. Br J Cancer (1987) 1.18
Caffeine promotes ethanol drinking in rats. Examination using a limited-access free choice paradigm. Alcohol (2000) 1.17
Permanent anatomic closure of the ductus arteriosus in newborn baboons: the roles of postnatal constriction, hypoxia, and gestation. Pediatr Res (1999) 1.17
Oxygen dependence of binding of misonidazole to rodent and human tumors in vitro. Cancer Res (1987) 1.16
Identification of hypoxia in cells and tissues of epigastric 9L rat glioma using EF5 [2-(2-nitro-1H-imidazol-1-yl)-N-(2,2,3,3,3-pentafluoropropyl) acetamide]. Br J Cancer (1995) 1.16
The extracellular domain of CD45 controls association with the CD4-T cell receptor complex and the response to antigen-specific stimulation. J Exp Med (1996) 1.16
Immobilized IL-8 triggers progressive activation of neutrophils rolling in vitro on P-selectin and intercellular adhesion molecule-1. J Immunol (2001) 1.15
Bidirectional effects of GABAergic agonists and antagonists on maintenance of voluntary ethanol intake in rats. Pharmacol Biochem Behav (1993) 1.15
Transient neonatal hyperthyrotrophinaemia: a serum abnormality due to transplacentally acquired antibody to thyroid stimulating hormone. Br Med J (Clin Res Ed) (1983) 1.15
A thin-film culturing technique allowing rapid gas-liquid equilibration (6 sec) with no toxicity to mammalian cells. Radiat Res (1984) 1.14
G6PD deficient cells and the bioreduction of disulfides: effects of DHEA, GSH depletion and phenylarsine oxide. Biochem Biophys Res Commun (2000) 1.14
Kinetics of immunoglobulin production by cultured human peripheral blood lymphocytes. J Immunol Methods (1978) 1.13
Accuracy, efficiency and robustness of four algorithms allowing full sibship reconstruction from DNA marker data. Mol Ecol (2004) 1.11
Mechanism of copper-catalyzed autoxidation of cysteine. Free Radic Res (1999) 1.11
Antimicrobial activity of cefmenoxime compared with those of other cephalosporins. Antimicrob Agents Chemother (1983) 1.10
Induction of apoptosis at different oxygen tensions: evidence that oxygen radicals do not mediate apoptotic signaling. Cancer Res (1995) 1.10
Diffusion of ceftriaxone into the cerebrospinal fluid of adults. J Antimicrob Chemother (1984) 1.09
Binding of misonidazole to hypoxic cells in monolayer and spheroid culture: evidence that a side-chain label is bound as efficiently as a ring label. Br J Cancer (1985) 1.08
Magnetic resonance microscopy of chick embryos in ovo. Teratology (1988) 1.08
Plateau phase in growth induced by hypoxia. Int J Radiat Biol Relat Stud Phys Chem Med (1973) 1.08
Mapping of the vascular endothelial growth factor-producing hypoxic cells in multicellular tumor spheroids using a hypoxia-specific marker. Cancer Res (1995) 1.08
A new, water soluble, phosphor for oxygen measurements in vivo. Adv Exp Med Biol (1997) 1.08
Biodistribution of the nitroimidazole EF5 (2-[2-nitro-1H-imidazol-1-yl]-N-(2,2,3,3,3-pentafluoropropyl) acetamide) in mice bearing subcutaneous EMT6 tumors. J Pharmacol Exp Ther (1996) 1.07
Geographical distribution of subclinical autoimmune thyroid disease in Britain: a study using highly sensitive direct assays for autoantibodies to thyroglobulin and thyroid peroxidase. Acta Endocrinol (Copenh) (1990) 1.07
Origin of cell populations after bone marrow transplantation. Analysis using DNA sequence polymorphisms. J Clin Invest (1985) 1.07
CTL adhesion and antigen recognition are discrete steps in the human CTL-target cell interaction. J Immunol (1987) 1.07
Hypoxia and VEGF mRNA expression in human tumors. Neoplasia (2002) 1.06
Thyroid-stimulating immunoglobulins in ophthalmic Graves' disease. Clin Endocrinol (Oxf) (1977) 1.05
Binding of thyroid stimulators to thyroid membranes. FEBS Lett (1974) 1.05
Prevention of pristane-induced arthritis by the oral administration of type II collagen. Immunology (1993) 1.05
Hypoxia and necrosis in rat 9L glioma and Morris 7777 hepatoma tumors: comparative measurements using EF5 binding and the Eppendorf needle electrode. Int J Radiat Oncol Biol Phys (2000) 1.05
Thyroglobulin and microsomal autoantibody production by cultures of Hashimoto peripheral blood lymphocytes. Immunology (1979) 1.04
Genetic controls of recombination I. The recombination-2 gene of Neurospora crassa. Heredity (Edinb) (1966) 1.04
The farnesyltransferase inhibitor L744,832 reduces hypoxia in tumors expressing activated H-ras. Cancer Res (2001) 1.04
Binding of misonidazole to V79 spheroids and fragments of Dunning rat prostatic and human colon carcinomas in vitro: diffusion of oxygen and reactive metabolites. Int J Radiat Oncol Biol Phys (1984) 1.03
High-performance liquid chromatographic analysis of the new antitumour drug SK&F 104864-A (NSC 609699) in plasma. J Pharm Biomed Anal (1990) 1.03
Monoclonal and oligoclonal gammopathy after bone marrow transplantation. Blood (1989) 1.03
Metabolism induced binding of 14C-misonidazole to hypoxic cells: kinetic dependence on oxygen concentration and misonidazole concentration. Int J Radiat Oncol Biol Phys (1984) 1.03
Studies of thyroglobulin autoantibody synthesis using a micro-ELISA assay. Immunol Lett (1982) 1.02
Aspirin does not inhibit adenosine diphosphate-induced platelet alpha-granule release. Blood (1993) 1.02
Isolation of Actinomyces species and Eikenella corrodens from patients with chronic diffuse sclerosing osteomyelitis. J Oral Maxillofac Surg (1994) 1.02
Noninvasive detection of tumor hypoxia using the 2-nitroimidazole [18F]EF1. J Nucl Med (2000) 1.01