Published in Clin Cancer Res on December 15, 2004
Salivary microRNA: discovery, characterization, and clinical utility for oral cancer detection. Clin Cancer Res (2009) 3.86
Salivary proteomic and genomic biomarkers for primary Sjögren's syndrome. Arthritis Rheum (2007) 2.90
Salivary proteomics for oral cancer biomarker discovery. Clin Cancer Res (2008) 2.81
Salivary transcriptomic biomarkers for detection of resectable pancreatic cancer. Gastroenterology (2009) 2.13
Nanostructural and transcriptomic analyses of human saliva derived exosomes. PLoS One (2010) 2.11
Transcriptomic dissection of tongue squamous cell carcinoma. BMC Genomics (2008) 2.09
Salivary 8-hydroxy-2-deoxyguanosine, malondialdehyde, vitamin C, and vitamin E in oral pre-cancer and cancer: diagnostic value and free radical mechanism of action. Clin Oral Investig (2015) 2.04
Capillary electrophoresis mass spectrometry-based saliva metabolomics identified oral, breast and pancreatic cancer-specific profiles. Metabolomics (2009) 2.03
Saliva: an emerging biofluid for early detection of diseases. Am J Dent (2009) 1.91
Molecular pathology of head and neck cancer: implications for diagnosis, prognosis, and treatment. Annu Rev Pathol (2009) 1.88
Electrochemical sensor for multiplex biomarkers detection. Clin Cancer Res (2009) 1.67
Saliva: diagnostics and therapeutic perspectives. Oral Dis (2010) 1.50
Global expression-based classification of lymph node metastasis and extracapsular spread of oral tongue squamous cell carcinoma. Neoplasia (2006) 1.44
Discovery and preclinical validation of salivary transcriptomic and proteomic biomarkers for the non-invasive detection of breast cancer. PLoS One (2010) 1.43
Human saliva proteome and transcriptome. J Dent Res (2006) 1.43
Exon-level expression profiling: a comprehensive transcriptome analysis of oral fluids. Clin Chem (2008) 1.38
Systemic disease-induced salivary biomarker profiles in mouse models of melanoma and non-small cell lung cancer. PLoS One (2009) 1.35
Ultrasensitive detection of cancer biomarkers in the clinic by use of a nanostructured microfluidic array. Anal Chem (2012) 1.34
Salivary biomarkers: toward future clinical and diagnostic utilities. Clin Microbiol Rev (2013) 1.34
Identification of a biomarker for sleep drive in flies and humans. Proc Natl Acad Sci U S A (2006) 1.32
Prevalidation of salivary biomarkers for oral cancer detection. Cancer Epidemiol Biomarkers Prev (2012) 1.30
Characterization of salivary RNA by cDNA library analysis. Arch Oral Biol (2006) 1.27
The landscape of microRNA, Piwi-interacting RNA, and circular RNA in human saliva. Clin Chem (2014) 1.26
Bio/abiotic interface constructed from nanoscale DNA dendrimer and conducting polymer for ultrasensitive biomolecular diagnosis. Small (2009) 1.22
Oral squamous cell carcinoma detection by salivary biomarkers in a Serbian population. Oral Oncol (2010) 1.18
Proinflammatory mediators upregulate snail in head and neck squamous cell carcinoma. Clin Cancer Res (2009) 1.17
Genomic targets in saliva. Ann N Y Acad Sci (2007) 1.16
Salivary biomarker development using genomic, proteomic and metabolomic approaches. Genome Med (2012) 1.16
Development of transcriptomic biomarker signature in human saliva to detect lung cancer. Cell Mol Life Sci (2012) 1.10
Oral premalignancy: new methods of detection and treatment. Curr Oncol Rep (2006) 1.09
Salivary Genomics, Transcriptomics and Proteomics: The Emerging Concept of the Oral Ecosystem and their Use in the Early Diagnosis of Cancer and other Diseases. Curr Genomics (2008) 1.09
Diagnostic aids for detection of oral precancerous conditions. Int J Oral Sci (2013) 1.09
Exciting new advances in oral cancer diagnosis: avenues to early detection. Head Neck Oncol (2011) 1.06
AUF1 and HuR proteins stabilize interleukin-8 mRNA in human saliva. J Dent Res (2008) 1.04
The role of human papillomavirus in the pathogenesis of head & neck squamous cell carcinoma: an overview. Infect Agent Cancer (2011) 1.04
Salivary markers for oral cancer detection. Open Dent J (2010) 1.03
Advances and Perspectives in the Molecular Diagnosis of Head and Neck Cancer. Expert Opin Med Diagn (2010) 1.03
Electrochemical detection of low-copy number salivary RNA based on specific signal amplification with a hairpin probe. Nucleic Acids Res (2008) 1.02
S100P: a novel therapeutic target for cancer. Amino Acids (2010) 1.01
Salivary mRNA targets for cancer diagnostics. Oral Oncol (2007) 0.99
Salivary microRNAs and oral cancer detection. Methods Mol Biol (2013) 0.98
Salivary biomarkers for detection of oral squamous cell carcinoma - current state and recent advances. Curr Oral Health Rep (2014) 0.96
Clinical relevance of nine transcriptional molecular markers for the diagnosis of head and neck squamous cell carcinoma in tissue and saliva rinse. BMC Cancer (2009) 0.96
Salivary biomarkers in psychobiological medicine. Bioinformation (2006) 0.96
Calcium-binding protein S100P and cancer: mechanisms and clinical relevance. J Cancer Res Clin Oncol (2011) 0.96
Detection of tumor cell-specific mRNA and protein in exosome-like microvesicles from blood and saliva. PLoS One (2014) 0.95
Proteomic analysis of whole human saliva detects enhanced expression of interleukin-1 receptor antagonist, thioredoxin and lipocalin-1 in cigarette smokers compared to non-smokers. Int J Mol Sci (2010) 0.94
Pro-inflammatory genes as biomarkers and therapeutic targets in oral squamous cell carcinoma. J Biol Chem (2010) 0.94
Saliva as a diagnostic tool for oral and systemic diseases. J Oral Biol Craniofac Res (2015) 0.93
A universal pre-analytic solution for concurrent stabilization of salivary proteins, RNA and DNA at ambient temperature. Arch Oral Biol (2008) 0.93
Salivary Diagnostics: Amazing as it might seem, doctors can detect and monitor diseases using molecules found in a sample of spit. Am Sci (2008) 0.91
Cross-translational studies in human and Drosophila identify markers of sleep loss. PLoS One (2013) 0.91
Urinary metabolite markers of precocious puberty. Mol Cell Proteomics (2011) 0.91
CTIP2 expression in human head and neck squamous cell carcinoma is linked to poorly differentiated tumor status. PLoS One (2009) 0.91
Non-coding RNAs in saliva: emerging biomarkers for molecular diagnostics. Int J Mol Sci (2015) 0.90
Chipping away at diagnostics for neurodegenerative diseases. Neurobiol Dis (2009) 0.89
Transcriptomic analyses of saliva. Methods Mol Biol (2010) 0.89
Improving oral cancer survival: the role of dental providers. J Calif Dent Assoc (2009) 0.89
Looking in the mouth for noninvasive gene expression-based methods to detect oral, oropharyngeal, and systemic cancer. ISRN Oncol (2012) 0.89
Saliva: A diagnostic biomarker of periodontal diseases. J Indian Soc Periodontol (2011) 0.89
Science behind human saliva. J Nat Sci Biol Med (2011) 0.86
Extracellular RNAs: development as biomarkers of human disease. J Extracell Vesicles (2015) 0.85
Levels of potential oral cancer salivary mRNA biomarkers in oral cancer patients in remission and oral lichen planus patients. Clin Oral Investig (2013) 0.85
Searching for molecular markers in head and neck squamous cell carcinomas (HNSCC) by statistical and bioinformatic analysis of larynx-derived SAGE libraries. BMC Med Genomics (2008) 0.85
Salivary protein factors are elevated in breast cancer patients. Mol Med Rep (2011) 0.85
The circulating transcriptome as a source of non-invasive cancer biomarkers: concepts and controversies of non-coding and coding RNA in body fluids. J Cell Mol Med (2015) 0.85
Update on molecular diagnostic tests in head and neck cancer. Semin Oncol (2008) 0.84
Great expectorations: the potential of salivary 'omic' approaches in neonatal intensive care. J Perinatol (2014) 0.84
Quantitative analysis of differentially expressed saliva proteins in human immunodeficiency virus type 1 (HIV-1) infected individuals. Anal Chim Acta (2013) 0.83
Opportunities and challenges facing biomarker development for personalized head and neck cancer treatment. Head Neck (2012) 0.83
Toward early oral cancer detection using gene expression profiling of saliva: a thoroughfare or dead end? Clin Cancer Res (2004) 0.83
Evaluation of a novel saliva-based epidermal growth factor receptor mutation detection for lung cancer: A pilot study. Thorac Cancer (2016) 0.83
The use of salivary cytokines as a screening tool for oral squamous cell carcinoma : A review of the literature. J Oral Maxillofac Pathol (2012) 0.82
New technologies for studying the complexity of oral diseases. Oral Dis (2011) 0.82
Salivary extracellular noncoding RNA: emerging biomarkers for molecular diagnostics. Clin Ther (2015) 0.82
Updated overview of current biomarkers in head and neck carcinoma. World J Methodol (2016) 0.82
Identification of salivary metabolomic biomarkers for oral cancer screening. Sci Rep (2016) 0.82
Salivary protein and solCD44 levels as a potential screening tool for early detection of head and neck squamous cell carcinoma. Head Neck (2011) 0.81
MicroRNAs in Head and Neck Squamous Cell Carcinoma (HNSCC) and Oral Squamous Cell Carcinoma (OSCC). Cancers (Basel) (2010) 0.81
Insights into Neonatal Oral Feeding through the Salivary Transcriptome. Int J Pediatr (2012) 0.80
Salivary biomarkers in the diagnosis of periodontal diseases. J Calif Dent Assoc (2013) 0.80
The preferences of adult outpatients in medical or dental care settings for giving saliva, urine or blood for clinical testing. J Am Dent Assoc (2008) 0.80
Salivary Biomarkers for Detection of Oral Squamous Cell Carcinoma in a Taiwanese Population. Clin Cancer Res (2016) 0.79
Saliva as a non-invasive diagnostic tool for inflammation and insulin-resistance. World J Diabetes (2014) 0.79
Advancing Point-of-Care (PoC) Testing Using Human Saliva as Liquid Biopsy. Diagnostics (Basel) (2017) 0.78
Noninvasive molecular detection of head and neck squamous cell carcinoma: an exploratory analysis. Diagn Mol Pathol (2009) 0.78
Salivary diagnostics using a portable point-of-service platform: a review. Clin Ther (2015) 0.78
Protease-activated Receptor-2 (PAR-2)-mediated Nf-κB Activation Suppresses Inflammation-associated Tumor Suppressor MicroRNAs in Oral Squamous Cell Carcinoma. J Biol Chem (2016) 0.78
Interleukin 1β-A Potential Salivary Biomarker for Cancer Progression? Biomark Cancer (2015) 0.77
Interleukin-1 beta transactivates epidermal growth factor receptor via the CXCL1-CXCR2 axis in oral cancer. Oncotarget (2015) 0.76
Exploring the neonatal salivary transcriptome: technical optimization and clinical applications. Clin Biochem (2011) 0.76
Hexokinase 2 enhances the metastatic potential of tongue squamous cell carcinoma via the SOD2-H2O2 pathway. Oncotarget (2016) 0.76
DUSP1 phosphatase regulates the proinflammatory milieu in head and neck squamous cell carcinoma. Cancer Res (2014) 0.76
The life and works of S100P - from conception to cancer. Am J Cancer Res (2016) 0.76
miRNAs As Diagnostic and Prognostic Biomarkers in Pancreatic Ductal Adenocarcinoma and Its Precursor Lesions: A Review. Biomark Insights (2015) 0.76
Salivary Antimicrobial Peptides in Early Detection of Periodontitis. Front Cell Infect Microbiol (2015) 0.76
Chronic periodontitis can affect the levels of potential oral cancer salivary mRNA biomarkers. J Periodontal Res (2016) 0.75
A study of salivary lactate dehydrogenase isoenzyme levels in patients with oral leukoplakia and squamous cell carcinoma by gel electrophoresis method. J Oral Maxillofac Pathol (2014) 0.75
Data from human salivary proteome - A resource of potential biomarkers for oral cancer. Data Brief (2015) 0.75
Salivary RNA signatures in oral cancer detection. Anal Cell Pathol (Amst) (2014) 0.75
Gene expression analysis reveals matrilysin as a key regulator of pulmonary fibrosis in mice and humans. Proc Natl Acad Sci U S A (2002) 4.00
Salivary microRNA: discovery, characterization, and clinical utility for oral cancer detection. Clin Cancer Res (2009) 3.86
Tongue and tonsil carcinoma: increasing trends in the U.S. population ages 20-44 years. Cancer (2005) 3.79
Cocaine-induced dendritic spine formation in D1 and D2 dopamine receptor-containing medium spiny neurons in nucleus accumbens. Proc Natl Acad Sci U S A (2006) 3.68
Impact of obesity on biochemical control after radical prostatectomy for clinically localized prostate cancer: a report by the Shared Equal Access Regional Cancer Hospital database study group. J Clin Oncol (2003) 3.62
Propionibacterium acnes strain populations in the human skin microbiome associated with acne. J Invest Dermatol (2013) 3.32
Modified Mallampati test, thyromental distance and inter-incisor gap are the best predictors of difficult laryngoscopy in West Africans. Can J Anaesth (2005) 3.22
Rare amplicons implicate frequent deregulation of cell fate specification pathways in oral squamous cell carcinoma. Oncogene (2005) 2.99
Salivary proteomic and genomic biomarkers for primary Sjögren's syndrome. Arthritis Rheum (2007) 2.90
Salivary proteomics for oral cancer biomarker discovery. Clin Cancer Res (2008) 2.81
Surgery for papillary thyroid carcinoma: is lobectomy enough? Arch Otolaryngol Head Neck Surg (2010) 2.63
The proteomes of human parotid and submandibular/sublingual gland salivas collected as the ductal secretions. J Proteome Res (2008) 2.53
Interleukin 6 and interleukin 8 as potential biomarkers for oral cavity and oropharyngeal squamous cell carcinoma. Arch Otolaryngol Head Neck Surg (2004) 2.46
Safety and efficacy of laryngeal mask airway Supreme versus laryngeal mask airway ProSeal: a randomized controlled trial. Eur J Anaesthesiol (2010) 2.42
Human body fluid proteome analysis. Proteomics (2006) 2.39
Variations of oral microbiota are associated with pancreatic diseases including pancreatic cancer. Gut (2011) 2.38
Large-scale identification of proteins in human salivary proteome by liquid chromatography/mass spectrometry and two-dimensional gel electrophoresis-mass spectrometry. Proteomics (2005) 2.34
Prognostic impact of micrometastases in colon cancer: interim results of a prospective multicenter trial. Ann Surg (2007) 2.28
Insights into the molecular basis of the hormonal control of molting and metamorphosis from Manduca sexta and Drosophila melanogaster. Insect Biochem Mol Biol (2003) 2.27
β-cell mass and turnover in humans: effects of obesity and aging. Diabetes Care (2012) 2.20
IκB kinase regulates social defeat stress-induced synaptic and behavioral plasticity. J Neurosci (2011) 2.15
Management choices for the difficult airway by anesthesiologists in Canada. Can J Anaesth (2002) 2.14
Salivary transcriptomic biomarkers for detection of resectable pancreatic cancer. Gastroenterology (2009) 2.13
Nanostructural and transcriptomic analyses of human saliva derived exosomes. PLoS One (2010) 2.11
Transcriptomic dissection of tongue squamous cell carcinoma. BMC Genomics (2008) 2.09
Capillary electrophoresis mass spectrometry-based saliva metabolomics identified oral, breast and pancreatic cancer-specific profiles. Metabolomics (2009) 2.03
Use of a tracheal tube introducer guide to facilitate difficult intubation with a video laryngoscope. Can J Anaesth (2014) 1.99
Cervical spine overflexion in a halo orthosis contributes to complete upper airway obstruction during awake bronchoscopic intubation: a case report. Can J Anaesth (2014) 1.97
The feasibility of measuring renal blood flow using transesophageal echocardiography in patients undergoing cardiac surgery. Anesth Analg (2009) 1.97
Identification of N-linked glycoproteins in human saliva by glycoprotein capture and mass spectrometry. J Proteome Res (2006) 1.96
Effect of duration of fixation on quantitative reverse transcription polymerase chain reaction analyses. Mod Pathol (2002) 1.95
Growth inhibitory effect of low fat diet on prostate cancer cells: results of a prospective, randomized dietary intervention trial in men with prostate cancer. J Urol (2010) 1.94
Characterization of RNA in saliva. Clin Chem (2006) 1.93
MicroRNA-138 suppresses invasion and promotes apoptosis in head and neck squamous cell carcinoma cell lines. Cancer Lett (2009) 1.92
Involvement of DARPP-32 phosphorylation in the stimulant action of caffeine. Nature (2002) 1.91
MicroRNA-7 targets IGF1R (insulin-like growth factor 1 receptor) in tongue squamous cell carcinoma cells. Biochem J (2010) 1.91
Saliva: an emerging biofluid for early detection of diseases. Am J Dent (2009) 1.91
Regulation of synaptojanin 1 by cyclin-dependent kinase 5 at synapses. Proc Natl Acad Sci U S A (2004) 1.84
Downregulation of the Rho GTPase signaling pathway is involved in the microRNA-138-mediated inhibition of cell migration and invasion in tongue squamous cell carcinoma. Int J Cancer (2010) 1.81
Lung cancer chemoprevention with celecoxib in former smokers. Cancer Prev Res (Phila) (2011) 1.77
Elimination of preoperative testing in ambulatory surgery. Anesth Analg (2009) 1.76
Retrospective audit of the air-Q intubating laryngeal airway as a conduit for tracheal intubation in pediatric patients with a difficult airway. Paediatr Anaesth (2010) 1.73
FOXC1 is a potential prognostic biomarker with functional significance in basal-like breast cancer. Cancer Res (2010) 1.73
Myeloid suppressor cell depletion augments antitumor activity in lung cancer. PLoS One (2012) 1.70
MicroRNA profiling and head and neck cancer. Comp Funct Genomics (2009) 1.68
MicroRNA-138 suppresses epithelial-mesenchymal transition in squamous cell carcinoma cell lines. Biochem J (2011) 1.67
Serum circulating human mRNA profiling and its utility for oral cancer detection. J Clin Oncol (2006) 1.67
Electrochemical sensor for multiplex biomarkers detection. Clin Cancer Res (2009) 1.67
The prognostic effect of micrometastases in previously staged lymph node negative (N0) colorectal carcinoma: a meta-analysis. Ann Surg Oncol (2006) 1.66
Saliva as a diagnostic tool for periodontal disease: current state and future directions. Periodontol 2000 (2009) 1.66
Increased nitric oxide levels and iNOS over-expression in oral squamous cell carcinoma. Oral Oncol (2005) 1.65
Krüppel homolog 1 (Kr-h1) mediates juvenile hormone action during metamorphosis of Drosophila melanogaster. Mech Dev (2007) 1.65
Hyalinizing clear cell carcinoma: case series and comprehensive review of the literature. Cancer (2009) 1.64
Should a positive surgical margin following radical prostatectomy be pathological stage T2 or T3? Results from the SEARCH database. J Urol (2003) 1.63
The FLAMES score accurately predicts mortality risk in burn patients. J Trauma (2008) 1.63
Kuttner tumor (chronic sclerosing sialadenitis). Am J Otolaryngol (2002) 1.63
The Effects of Continuous Positive Airway Pressure on Postoperative Outcomes in Obstructive Sleep Apnea Patients Undergoing Surgery: A Systematic Review and Meta-analysis. Anesth Analg (2015) 1.63
Surgical repositioning of dislocated capsular tension rings. Ophthalmology (2005) 1.62
Use of sonography for airway assessment: an observational study. J Ultrasound Med (2010) 1.62
Reduction of the efficacy of methotrexate by the use of folic acid: post hoc analysis from two randomized controlled studies. Arthritis Rheum (2005) 1.61
Histone demethylases KDM4B and KDM6B promotes osteogenic differentiation of human MSCs. Cell Stem Cell (2012) 1.58
Late-onset macular degeneration and long anterior lens zonules result from a CTRP5 gene mutation. Invest Ophthalmol Vis Sci (2005) 1.57
Quantitative F18-fluorodeoxyglucose positron emission tomography accurately characterizes peripheral nerve sheath tumors as malignant or benign. Cancer (2010) 1.56
MicroRNA-222 regulates cell invasion by targeting matrix metalloproteinase 1 (MMP1) and manganese superoxide dismutase 2 (SOD2) in tongue squamous cell carcinoma cell lines. Cancer Genomics Proteomics (2009) 1.55
miR-181a shows tumor suppressive effect against oral squamous cell carcinoma cells by downregulating K-ras. Biochem Biophys Res Commun (2010) 1.53
Comparison of toxicity associated with early morning versus late afternoon radiotherapy in patients with head-and-neck cancer: a prospective randomized trial of the National Cancer Institute of Canada Clinical Trials Group (HN3). Int J Radiat Oncol Biol Phys (2008) 1.52
Systematic comparison of the human saliva and plasma proteomes. Proteomics Clin Appl (2009) 1.51
Prognostic significance of molecular upstaging of paraffin-embedded sentinel lymph nodes in melanoma patients. J Clin Oncol (2004) 1.50
Effect of altering dietary omega-6/omega-3 fatty acid ratios on prostate cancer membrane composition, cyclooxygenase-2, and prostaglandin E2. Clin Cancer Res (2006) 1.50
Randomized clinical trial of brewed green and black tea in men with prostate cancer prior to prostatectomy. Prostate (2014) 1.47
FDG-PET/CT imaging predicts histopathologic treatment responses after the initial cycle of neoadjuvant chemotherapy in high-grade soft-tissue sarcomas. Clin Cancer Res (2009) 1.47
Solitary fibrous tumor of the head and neck. Oral Surg Oral Med Oral Pathol Oral Radiol Endod (2010) 1.47
Subconjunctival lidocaine before laser treatment: a randomized trial. Ophthalmology (2010) 1.46
Green and black tea consumption and risk of stroke: a meta-analysis. Stroke (2009) 1.46
Fluoxetine, but not other selective serotonin uptake inhibitors, increases norepinephrine and dopamine extracellular levels in prefrontal cortex. Psychopharmacology (Berl) (2002) 1.46
A Comparative Assessment of Observational Medical Outcomes Partnership and Mini-Sentinel Common Data Models and Analytics: Implications for Active Drug Safety Surveillance. Drug Saf (2015) 1.45
Retinal vein occlusion and traditional risk factors for atherosclerosis. Arch Ophthalmol (2008) 1.44
Global expression-based classification of lymph node metastasis and extracapsular spread of oral tongue squamous cell carcinoma. Neoplasia (2006) 1.44
Salivary diagnostics: enhancing disease detection and making medicine better. Eur J Dent Educ (2008) 1.44
Discovery and preclinical validation of salivary transcriptomic and proteomic biomarkers for the non-invasive detection of breast cancer. PLoS One (2010) 1.43
Tracheal extubation with a laryngeal mask airway and exchange catheter in a patient with a difficult airway. Can J Anaesth (2013) 1.42