Published in J Steroid Biochem Mol Biol on March 01, 1992
Ethinylestradiol does not enhance the expression of nitric oxide synthase in bovine endothelial cells but increases the release of bioactive nitric oxide by inhibiting superoxide anion production. Proc Natl Acad Sci U S A (1996) 1.04
Progesterone and RU486: opposing effects on human sperm. Proc Natl Acad Sci U S A (1994) 0.94
Convergent synthesis of a steroidal antiestrogen-mitomycin C hybrid using "click" chemistry. Org Biomol Chem (2012) 0.78
Synthesis and evaluation of 11β-(4-substituted phenyl) estradiol analogs: transition from estrogen receptor agonists to antagonists. Bioorg Med Chem (2012) 0.76
Non-steroidal antiandrogens: synthesis and biological profile of high-affinity ligands for the androgen receptor. J Steroid Biochem Mol Biol (1994) 1.84
RU 38486: potent antiglucocorticoid activity correlated with strong binding to the cytosolic glucocorticoid receptor followed by an impaired activation. J Steroid Biochem (1984) 1.46
[The effects of an antiprogesterone steroid in women: interruption of the menstrual cycle and of early pregnancy]. C R Seances Acad Sci III (1982) 1.26
Dextroamphetamine with morphine for the treatment of postoperative pain. N Engl J Med (1977) 1.18
Autoradiographic localization of glucocorticosteroid and progesterone binding sites in the human post-mortem brain. J Steroid Biochem (1986) 1.08
RU 38486: a potent antiglucocorticoid in vitro and in vivo. J Steroid Biochem (1985) 1.07
17 alpha-alkynyl-11 beta, 17-dihydroxyandrostane derivatives : a new class of potent glucocorticoids. Steroids (1981) 1.01
An analytical quantification of mass fluxes and natural attenuation rate constants at a former gasworks site. J Contam Hydrol (2001) 0.97
Progesterone and RU486: opposing effects on human sperm. Proc Natl Acad Sci U S A (1994) 0.94
Transition probability/Markov chain analyses of DNAPL source zones and plumes. Ground Water (2006) 0.93
RU 486. Sci Am (1990) 0.93
Progesterone binding in the immature mouse and rat uterus. Steroids (1973) 0.91
Comparative study of estrogen action. Mol Pharmacol (1973) 0.90
Antiandrogenic activity of a series of des-A-steroid derivatives. J Med Chem (1985) 0.89
Pharmacological profile of RU 58642, a potent systemic antiandrogen for the treatment of androgen-dependent disorders. J Steroid Biochem Mol Biol (1998) 0.89
Psychosocial aspects of neoplastic disease: II. Affective and cognitive effects of chemotherapy in cancer patients. Am J Psychiatry (1980) 0.89
Contragestion by antiprogestin RU 486: a review. Arch Gynecol Obstet (1987) 0.87
Steroid hormone receptors and pharmacology. J Steroid Biochem (1980) 0.87
Mechanism of action of an antiprogesterone, RU486, in the rabbit endometrium. Effects of RU486 on the progesterone receptor and on the expression of the uteroglobin gene. Eur J Biochem (1985) 0.85
Design of ligands for the glucocorticoid and progestin receptors. Biochem Soc Trans (1991) 0.85
Steroid hormone receptors in human meningiomas, gliomas and brain metastases. J Neurooncol (1983) 0.84
RU 58841, a new specific topical antiandrogen: a candidate of choice for the treatment of acne, androgenetic alopecia and hirsutism. J Steroid Biochem Mol Biol (1994) 0.84
A progesterone metabolite enhances the activity of the GABAA receptor complex at the pituitary level. Eur J Pharmacol (1989) 0.82
Properties of the cytoplasmic progestin-binding protein in the rabbit uterus. Endocrinology (1977) 0.81
11 beta-Amidoalkoxyphenyl estradiols, a new series of pure antiestrogens. J Steroid Biochem Mol Biol (1994) 0.81
Residues in the ligand binding domain that confer progestin or glucocorticoid specificity and modulate the receptor transactivation capacity. Mol Endocrinol (2000) 0.81
Sequences in the ligand-binding domains of the human androgen and progesterone receptors which determine their distinct ligand identities. J Mol Endocrinol (1997) 0.81
Specific progesterone receptors in dimethylbenzanthracene (DMBA)-induced mammary tumors. Steroids (1976) 0.80
Screening for anti-hormones by receptor studies. J Steroid Biochem (1975) 0.80
Antiglucocorticoid properties of RU 38486 in a differentiated hepatoma cell line. Biochem Pharmacol (1983) 0.80
Determination of oenothein B as the active 5-alpha-reductase-inhibiting principle of the folk medicine Epilobium parviflorum. J Nat Prod (1996) 0.80
Control of birth in rats by RU 486, an antiprogesterone compound. J Reprod Fertil (1987) 0.79
Regio and stereospecific synthesis of 11 beta-substituted 19-norsteroids. Influence of 11 beta-substitution on progesterone receptor affinity - (1). Steroids (1981) 0.79
Autoradiographic localization of glucocorticosteroid binding sites in rat brain after in vivo injection of [3H]RU 28362. Neurosci Lett (1988) 0.79
The effect of the antimineralocorticoid RU 28318 on aldosterone biosynthesis in vitro. J Steroid Biochem (1984) 0.79
History and perspectives of antiprogestins from the chemist's point of view. Hum Reprod (1994) 0.79
RU 58,668, a new pure antiestrogen inducing a regression of human mammary carcinoma implanted in nude mice. J Steroid Biochem Mol Biol (1994) 0.79
Synthesis of a fluorescent steroid derivative with high affinities for the glucocorticoid and progesterone receptors. Steroids (1994) 0.79
Steroidal affinity labels of the estrogen receptor alpha. 4. Electrophilic 11beta-aryl derivatives of estradiol. J Med Chem (2000) 0.79
RU 58668: further in vitro and in vivo pharmacological data related to its antitumoral activity. J Steroid Biochem Mol Biol (1996) 0.79
Progesterone binding in the immature rabbit and guinea pig uterus. Endocrinology (1974) 0.78
Switching agonistic, antagonistic, and mixed transcriptional responses to 11 beta-substituted progestins by mutation of the progesterone receptor. Mol Endocrinol (1992) 0.78
Structure-activity relationships of a new family of steroidal aromatase inhibitors. 1. Synthesis and evaluation of a series of analogs related to 19-[(methylthio)methyl]androstenedione (RU54115). J Med Chem (1996) 0.78
Progesterone-Progestin receptors. Basic Life Sci (1974) 0.78
Binding of progesterone and R 5020, a highly potent progestin, to human endometrium and myometrium. Contraception (1974) 0.77
Steroidal affinity labels of the estrogen receptor. 3. Estradiol 11 beta-n-alkyl derivatives bearing a terminal electrophilic group: antiestrogenic and cytotoxic properties. J Med Chem (1997) 0.77
Progesterone suppression of pregnancy lymphocytes is not mediated by glucocorticoid effect. Am J Reprod Immunol (1990) 0.77
Succinyldicholine and the basic ocular deviation. Am J Ophthalmol (1983) 0.77
Fertility control with RU 486. Horm Res (1987) 0.77
Preliminary pharmacokinetics and metabolism of novel non-steroidal antiandrogens in the rat: relation of their systemic activity to the formation of a common metabolite. J Steroid Biochem Mol Biol (1994) 0.77
[Effects of an anti-progestin steroid in women: interruption of the menstrual cycle or early pregnancy (author's transl)]. Contracept Fertil Sex (Paris) (1982) 0.77
Hypnotic efficacy of diphenhydramine, methapyrilene, and pentobarbital. Clin Pharmacol Ther (1975) 0.77
Synthesis of 11 beta-vinyl-19-norsteroids as potent progestins. Steroids (1982) 0.76
RU 486 development. Science (1990) 0.76
In vitro autoradiographic localization of [3H]corticosterone binding sites in rat hippocampus. Eur J Pharmacol (1984) 0.76
Biphenyls as surrogates of the steroidal backbone. Part 1: synthesis and estrogen receptor affinity of an original series of polysubstituted biphenyls. Bioorg Med Chem Lett (2001) 0.76
Synthesis and evaluation of a new series of mechanism-based aromatase inhibitors. J Med Chem (1992) 0.76
[Binding affinity to steroid hormone receptors and antiproliferative action on MCF-7 cells of coumarin derivatives and isoflavonoids]. Ann Pharm Fr (1999) 0.76
In vitro binding of tritiated glucocorticoids directly on unfixed rat brain sections. J Steroid Biochem (1984) 0.76
Antibacterial activity of RU44790, a new N-tetrazolyl monocyclic beta-lactam. Antimicrob Agents Chemother (1992) 0.75
Agenesis of the cecum and the ascending and transverse colon in a 12-yer-old cat. Can Vet J (1992) 0.75
19-Norprogestins. Synthesis and biological activity of 6-chloro-16-methylene-17 -hydroxy-19-nor-4,6-pregnadiene-3,20-dione 17-acetate. J Med Chem (1973) 0.75
RU 3117 a steroidal compound with high affinity for sigma sites in rat testis membranes. J Steroid Biochem Mol Biol (1996) 0.75
Relative potency of propiram and morphine for analgsia in man. J Clin Pharmacol New Drugs (1973) 0.75
[Some data on the asymmetric synthesis in the estradiol series]. Bull Soc Chim Fr (1967) 0.75
Synthesis and relative binding affinity to steroid receptors and antiproliferative activity on MCF-7 cells of 2,3-disubstituted indenes. Farmaco (1999) 0.75
[Epoxides of 5(10), 9(11)-estradienes]. Bull Soc Chim Fr (1970) 0.75
Influence of 6-azido and 6-thiocyanato substitution on progestational and corticoid activities and a structure-activity correlation in the delta6-6-substituted progestational series. J Med Chem (1973) 0.75
Succinyldicholine-induced return of the eyes to the basic deviation: a motion picture study. Ophthalmology (1980) 0.75
Assessing microbial degradation of o-xylene at field-scale from the reduction in mass flow rate combined with compound-specific isotope analyses. J Contam Hydrol (2004) 0.75
General structure-activity correlations of antihormones. Ann N Y Acad Sci (1995) 0.75
Exploration of the therapeutic potential of the antiestrogen RU 58668 in breast cancer treatment. Ann N Y Acad Sci (1995) 0.75
Another study: the patient's perspective. 1989. CANNT J (2008) 0.75
Synthesis of new fluorescent spirolactone derivatives: determination of their affinities for aldosterone receptors. Steroids (1989) 0.75
Biphenyls as surrogates of the steroidal backbone. Part 2: discovery of a novel family of non-steroidal 5-alpha-reductase inhibitors. Bioorg Med Chem Lett (2001) 0.75
Combined routes of administration to assay oral analgesia in postoperative pain. J Clin Pharmacol (1977) 0.75
New analogues of mifepristone with more dissociated antiprogesterone activities. J Steroid Biochem (1989) 0.75
[The effects of an antiprogesterone steroid in women: interruption of the menstrual cycle and of early pregnancy. Supplementary note]. C R Seances Acad Sci III (1983) 0.75