Published in Blood on January 11, 2005
B-cell diversity decreases in old age and is correlated with poor health status. Aging Cell (2008) 2.15
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A functional variant of SUMO4, a new I kappa B alpha modifier, is associated with type 1 diabetes. Nat Genet (2004) 4.95
The growth factor progranulin binds to TNF receptors and is therapeutic against inflammatory arthritis in mice. Science (2011) 4.76
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Arsenic trioxide controls the fate of the PML-RARalpha oncoprotein by directly binding PML. Science (2010) 4.52
Leaf nitrogen and phosphorus stoichiometry across 753 terrestrial plant species in China. New Phytol (2005) 4.20
Combination antifungal therapies for HIV-associated cryptococcal meningitis: a randomised trial. Lancet (2004) 4.14
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Efficient genome engineering in human pluripotent stem cells using Cas9 from Neisseria meningitidis. Proc Natl Acad Sci U S A (2013) 3.53
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Human CD4+ CD25hi Foxp3+ regulatory T cells are derived by rapid turnover of memory populations in vivo. J Clin Invest (2006) 3.25
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Tissue Doppler imaging is superior to strain rate imaging and postsystolic shortening on the prediction of reverse remodeling in both ischemic and nonischemic heart failure after cardiac resynchronization therapy. Circulation (2004) 3.12
Characterization of three H5N5 and one H5N8 highly pathogenic avian influenza viruses in China. Vet Microbiol (2013) 3.05
Multifunctional, high-level cytokine-producing Th1 cells in the lung, but not spleen, correlate with protection against Mycobacterium tuberculosis aerosol challenge in mice. J Immunol (2008) 3.04
New variant of porcine epidemic diarrhea virus, United States, 2014. Emerg Infect Dis (2014) 2.99
Adaptive optics parallel spectral domain optical coherence tomography for imaging the living retina. Opt Express (2005) 2.97
Biosynthesis of selenocysteine on its tRNA in eukaryotes. PLoS Biol (2007) 2.96
Suppression of renin-angiotensin gene expression in the kidney by paricalcitol. Kidney Int (2008) 2.95
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KIT kinase mutants show unique mechanisms of drug resistance to imatinib and sunitinib in gastrointestinal stromal tumor patients. Proc Natl Acad Sci U S A (2009) 2.84
Genome-wide association study in Asian populations identifies variants in ETS1 and WDFY4 associated with systemic lupus erythematosus. PLoS Genet (2010) 2.74
Amplitude-modulated continuous arterial spin-labeling 3.0-T perfusion MR imaging with a single coil: feasibility study. Radiology (2005) 2.69
Type I interferons produced by dendritic cells promote their phenotypic and functional activation. Blood (2002) 2.59
Blockade of attachment and fusion receptors inhibits HIV-1 infection of human cervical tissue. J Exp Med (2004) 2.58
Distinguishing cancer-associated missense mutations from common polymorphisms. Cancer Res (2007) 2.57
Remodeling of the enhancer landscape during macrophage activation is coupled to enhancer transcription. Mol Cell (2013) 2.55
Myocardial infarct size measurement in the mouse chronic infarction model: comparison of area- and length-based approaches. J Appl Physiol (1985) (2007) 2.52
Transforming growth factor-beta-regulated miR-24 promotes skeletal muscle differentiation. Nucleic Acids Res (2008) 2.44
A critical role of IFNgamma in priming MSC-mediated suppression of T cell proliferation through up-regulation of B7-H1. Cell Res (2008) 2.38
Cutting edge: enhancement of antibody responses through direct stimulation of B and T cells by type I IFN. J Immunol (2006) 2.38
MG53 constitutes a primary determinant of cardiac ischemic preconditioning. Circulation (2010) 2.35
The yak genome and adaptation to life at high altitude. Nat Genet (2012) 2.34
The draft genome of watermelon (Citrullus lanatus) and resequencing of 20 diverse accessions. Nat Genet (2012) 2.33
Impact of a baseline polymorphism on the emergence of resistance to the hepatitis C virus nonstructural protein 5A replication complex inhibitor, BMS-790052. Hepatology (2012) 2.29
Structure-function-folding relationship in a WW domain. Proc Natl Acad Sci U S A (2006) 2.28
Allergic symptoms, atopy, and geohelminth infections in a rural area of Ecuador. Am J Respir Crit Care Med (2003) 2.28
IL-15 promotes the survival of naive and memory phenotype CD8+ T cells. J Immunol (2003) 2.28
Recombinant MG53 protein modulates therapeutic cell membrane repair in treatment of muscular dystrophy. Sci Transl Med (2012) 2.27
Ultrahigh-resolution optical coherence tomography with monochromatic and chromatic aberration correction. Opt Express (2008) 2.26
Effect of albendazole treatments on the prevalence of atopy in children living in communities endemic for geohelminth parasites: a cluster-randomised trial. Lancet (2006) 2.25
Regulation of hunger-driven behaviors by neural ribosomal S6 kinase in Drosophila. Proc Natl Acad Sci U S A (2005) 2.23
Nuclear accumulation of the Arabidopsis immune receptor RPS4 is necessary for triggering EDS1-dependent defense. Curr Biol (2007) 2.20
Direct stimulation of T cells by type I IFN enhances the CD8+ T cell response during cross-priming. J Immunol (2006) 2.20
Peak early diastolic mitral annulus velocity by tissue Doppler imaging adds independent and incremental prognostic value. J Am Coll Cardiol (2003) 2.20
Combined vitamin D analog and AT1 receptor antagonist synergistically block the development of kidney disease in a model of type 2 diabetes. Kidney Int (2010) 2.18
Development of an integrated wireless sensor network micro-environmental monitoring system. ISA Trans (2008) 2.16
Interface-induced superconductivity and strain-dependent spin density waves in FeSe/SrTiO3 thin films. Nat Mater (2013) 2.15
Two-stage cooperative T cell receptor-peptide major histocompatibility complex-CD8 trimolecular interactions amplify antigen discrimination. Immunity (2011) 2.12
The effects of iron fortification on the gut microbiota in African children: a randomized controlled trial in Cote d'Ivoire. Am J Clin Nutr (2010) 2.10
Repetitive ischemia by coronary stenosis induces a novel window of ischemic preconditioning. Circulation (2008) 2.09
Detection and genetic characterization of deltacoronavirus in pigs, Ohio, USA, 2014. Emerg Infect Dis (2014) 2.08
Combination therapy with AT1 blocker and vitamin D analog markedly ameliorates diabetic nephropathy: blockade of compensatory renin increase. Proc Natl Acad Sci U S A (2008) 2.06
A prospectively measured serum biomarker for a tobacco-specific carcinogen and lung cancer in smokers. Cancer Epidemiol Biomarkers Prev (2009) 2.04
A novel tool to assess systolic asynchrony and identify responders of cardiac resynchronization therapy by tissue synchronization imaging. J Am Coll Cardiol (2005) 2.03
Fat deposition in dilated cardiomyopathy assessed by CMR. JACC Cardiovasc Imaging (2013) 2.00
An international effort towards developing standards for best practices in analysis, interpretation and reporting of clinical genome sequencing results in the CLARITY Challenge. Genome Biol (2014) 1.95
Presurgical nasoalveolar molding for cleft lip and palate: the application of digitally designed molds. Plast Reconstr Surg (2015) 1.93
Adaptive optics flood-illumination camera for high speed retinal imaging. Opt Express (2006) 1.92
Whole-genome sequencing of cultivated and wild peppers provides insights into Capsicum domestication and specialization. Proc Natl Acad Sci U S A (2014) 1.91
A murine model of isolated cardiac steatosis leads to cardiomyopathy. Hypertension (2011) 1.90
Cytosolic monothiol glutaredoxins function in intracellular iron sensing and trafficking via their bound iron-sulfur cluster. Cell Metab (2010) 1.89
MicroRNAs modulate the noncanonical transcription factor NF-kappaB pathway by regulating expression of the kinase IKKalpha during macrophage differentiation. Nat Immunol (2010) 1.87
Measuring retinal contributions to the optical Stiles-Crawford effect with optical coherence tomography. Opt Express (2008) 1.87
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Downregulation of transcription factor Oct4 induces an epithelial-to-mesenchymal transition via enhancement of Ca2+ influx in breast cancer cells. Biochem Biophys Res Commun (2011) 1.82
Cardiomyocyte-specific deletion of the vitamin D receptor gene results in cardiac hypertrophy. Circulation (2011) 1.81
Dynamics of the lakes in the middle and lower reaches of the Yangtze River basin, China, since late nineteenth century. Environ Monit Assess (2012) 1.80
On the Euclidean distance of images. IEEE Trans Pattern Anal Mach Intell (2005) 1.80
Yeast frataxin solution structure, iron binding, and ferrochelatase interaction. Biochemistry (2004) 1.80
Research on an Mg-Zn alloy as a degradable biomaterial. Acta Biomater (2009) 1.80
SHP-2 phosphatase negatively regulates the TRIF adaptor protein-dependent type I interferon and proinflammatory cytokine production. Immunity (2006) 1.79
Quantum dot imaging for embryonic stem cells. BMC Biotechnol (2007) 1.78
Inflammatory markers and risk of type 2 diabetes: a systematic review and meta-analysis. Diabetes Care (2013) 1.77
A facile and highly atom-economic approach to biaryl-containing medium-ring bislactones. Chem Commun (Camb) (2011) 1.77
Characterization of an influenza A virus isolated from pigs during an outbreak of respiratory disease in swine and people during a county fair in the United States. Vet Microbiol (2009) 1.77
Relationships between cigarette consumption and biomarkers of tobacco toxin exposure. Cancer Epidemiol Biomarkers Prev (2005) 1.76
Niche of harmful alga Aureococcus anophagefferens revealed through ecogenomics. Proc Natl Acad Sci U S A (2011) 1.76
Reduction of B cell turnover in chronic lymphocytic leukaemia. Br J Haematol (2008) 1.74
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Evaluation of carcinogen exposure in people who used "reduced exposure" tobacco products. J Natl Cancer Inst (2004) 1.74
Aldosterone receptor antagonism induces reverse remodeling when added to angiotensin receptor blockade in chronic heart failure. J Am Coll Cardiol (2007) 1.73
CD161++ CD8+ T cells, including the MAIT cell subset, are specifically activated by IL-12+IL-18 in a TCR-independent manner. Eur J Immunol (2013) 1.72
Telomere erosion in memory T cells induced by telomerase inhibition at the site of antigenic challenge in vivo. J Exp Med (2004) 1.71
Generation of a functional and durable vascular niche by the adenoviral E4ORF1 gene. Proc Natl Acad Sci U S A (2008) 1.69
Complete protein characterization using top-down mass spectrometry and ultraviolet photodissociation. J Am Chem Soc (2013) 1.69