Published in Genes Chromosomes Cancer on April 01, 2005
Expression of pro- and anti-angiogenic isoforms of VEGF is differentially regulated by splicing and growth factors. J Cell Sci (2008) 2.09
Defective splicing, disease and therapy: searching for master checkpoints in exon definition. Nucleic Acids Res (2006) 1.89
Novel c-CBL and CBL-b ubiquitin ligase mutations in human acute myeloid leukemia. Blood (2007) 1.83
Whole genome exon arrays identify differential expression of alternatively spliced, cancer-related genes in lung cancer. Nucleic Acids Res (2008) 1.63
Design of a bioactive small molecule that targets the myotonic dystrophy type 1 RNA via an RNA motif-ligand database and chemical similarity searching. J Am Chem Soc (2012) 1.44
Alternative inclusion of fibroblast growth factor receptor 2 exon IIIc in Dunning prostate tumors reveals unexpected epithelial mesenchymal plasticity. Proc Natl Acad Sci U S A (2006) 1.36
Method for generation of in vivo biotinylated recombinant antibodies by yeast mating. J Immunol Methods (2006) 1.32
Acute myeloid leukemia with the 8q22;21q22 translocation: secondary mutational events and alternative t(8;21) transcripts. Blood (2007) 1.29
The impact of multiple splice sites in human L1 elements. Gene (2008) 1.26
Comparative analysis of cancer genes in the human and chimpanzee genomes. BMC Genomics (2006) 1.10
Single-molecule analysis of protein-free U2-U6 snRNAs. Nat Struct Mol Biol (2009) 1.09
Increasing the relative expression of endogenous non-coding Steroid Receptor RNA Activator (SRA) in human breast cancer cells using modified oligonucleotides. Nucleic Acids Res (2009) 1.07
An LRP5 receptor with internal deletion in hyperparathyroid tumors with implications for deregulated WNT/beta-catenin signaling. PLoS Med (2007) 1.03
Organization and post-transcriptional processing of focal adhesion kinase gene. BMC Genomics (2006) 1.03
An isoform of ZBP-89 predisposes the colon to colitis. Nucleic Acids Res (2006) 1.02
Tumor suppressor function of androgen receptor coactivator ARA70alpha in prostate cancer. Am J Pathol (2010) 1.02
MADD, a splice variant of IG20, is indispensable for MAPK activation and protection against apoptosis upon tumor necrosis factor-alpha treatment. J Biol Chem (2009) 1.00
The beta-catenin/TCF4 pathway modifies alternative splicing through modulation of SRp20 expression. RNA (2008) 1.00
Caffeine regulates alternative splicing in a subset of cancer-associated genes: a role for SC35. Mol Cell Biol (2007) 0.99
TassDB: a database of alternative tandem splice sites. Nucleic Acids Res (2006) 0.97
Intron retention is a widespread mechanism of tumor-suppressor inactivation. Nat Genet (2015) 0.95
Functional pre- mRNA trans-splicing of coactivator CoAA and corepressor RBM4 during stem/progenitor cell differentiation. J Biol Chem (2009) 0.95
Network models of genome-wide association studies uncover the topological centrality of protein interactions in complex diseases. J Am Med Inform Assoc (2013) 0.95
Cofactor of BRCA1 modulates androgen-dependent transcription and alternative splicing. J Steroid Biochem Mol Biol (2007) 0.95
Differentiating alternative splice variant patterns of human telomerase reverse transcriptase in thyroid neoplasms. Thyroid (2008) 0.92
Re-splicing of mature mRNA in cancer cells promotes activation of distant weak alternative splice sites. Nucleic Acids Res (2012) 0.91
Aberrant splice variants of HAS1 (Hyaluronan Synthase 1) multimerize with and modulate normally spliced HAS1 protein: a potential mechanism promoting human cancer. J Biol Chem (2009) 0.91
Optimization of antitumor modulators of pre-mRNA splicing. J Med Chem (2013) 0.91
Development of a novel splice array platform and its application in the identification of alternative splice variants in lung cancer. BMC Genomics (2010) 0.91
Switched alternative splicing of oncogene CoAA during embryonal carcinoma stem cell differentiation. Nucleic Acids Res (2007) 0.89
Alternative pre-mRNA processing regulates cell-type specific expression of the IL4l1 and NUP62 genes. BMC Biol (2005) 0.87
Increased levels of noisy splicing in cancers, but not for oncogene-derived transcripts. Hum Mol Genet (2011) 0.85
Splicing up mdm2 for cancer proteome diversity. Genes Cancer (2012) 0.85
CD44, Hyaluronan, the Hematopoietic Stem Cell, and Leukemia-Initiating Cells. Front Immunol (2015) 0.84
Alternative splicing of pre-mRNA in cancer: focus on G protein-coupled peptide hormone receptors. Am J Pathol (2009) 0.83
Identifying alternative hyper-splicing signatures in MG-thymoma by exon arrays. PLoS One (2008) 0.83
GT198 Splice Variants Display Dominant-Negative Activities and Are Induced by Inactivating Mutations. Genes Cancer (2013) 0.83
Wrecked regulation of intrinsically disordered proteins in diseases: pathogenicity of deregulated regulators. Front Mol Biosci (2014) 0.82
A genetic screen for dominant modifiers of a small-wing phenotype in Drosophila melanogaster identifies proteins involved in splicing and translation. Genetics (2005) 0.82
The alternative TrkAIII splice variant targets the centrosome and promotes genetic instability. Mol Cell Biol (2009) 0.82
Alternatively spliced lysyl oxidase-like 4 isoforms have a pro-metastatic role in cancer. Clin Exp Metastasis (2012) 0.81
Doxorubicin and 5-fluorouracil induced accumulation and transcriptional activity of p53 are independent of the phosphorylation at serine 15 in MCF-7 breast cancer cells. Cancer Biol Ther (2014) 0.80
Alternative splicing and its impact as a cancer diagnostic marker. Genomics Inform (2012) 0.80
Post-transcriptional modifications modulate conformational dynamics in human U2-U6 snRNA complex. RNA (2013) 0.80
PTEN transcript variants caused by illegitimate splicing in "aged" blood samples and EBV-transformed cell lines. Hum Genet (2010) 0.80
Identification and characterization of PNRC splicing variants. Gene (2008) 0.79
Zinc finger transcription factors designed for bispecific coregulation of ErbB2 and ErbB3 receptors: insights into ErbB receptor biology. Mol Cell Biol (2005) 0.79
Role of pseudoexons and pseudointrons in human cancer. Int J Cell Biol (2013) 0.79
A large-scale RNAi-based mouse tumorigenesis screen identifies new lung cancer tumor suppressors that repress FGFR signaling. Cancer Discov (2014) 0.79
Alternative splicing of apoptosis-related genes in imatinib-treated K562 cells identified by exon array analysis. Int J Mol Med (2011) 0.78
Protein kinase a-dependent phosphorylation of serine 119 in the proto-oncogenic serine/arginine-rich splicing factor 1 modulates its activity as a splicing enhancer protein. Genes Cancer (2011) 0.78
Alteration of introns in a hyaluronan synthase 1 (HAS1) minigene convert Pre-mRNA [corrected] splicing to the aberrant pattern in multiple myeloma (MM): MM patients harbor similar changes. PLoS One (2013) 0.78
RNA biomarkers to facilitate the identification of aggressive prostate cancer. Mol Aspects Med (2015) 0.76
Fusion gene and splice variant analyses in liquid biopsies of lung cancer patients. Transl Lung Cancer Res (2016) 0.75
Mechanism of alternative splicing and its regulation. Biomed Rep (2014) 0.75
A novel splicing mutation in the SLC9A3R1 gene in tumors from ovarian cancer patients. Oncol Lett (2015) 0.75
Do Estrogen Receptor beta Polymorphisms Play A Role in the Pharmacogenetics of Estrogen Signaling? Curr Pharmacogenomics Person Med (2008) 0.75
Antibody-based proteomics to identify an apoptosis signature for early recurrence of hepatocellular carcinoma. Clin Proteomics (2016) 0.75
Challenges with advanced therapy medicinal products and how to meet them. Nat Rev Drug Discov (2010) 2.09
Cell-free microRNAs as diagnostic, prognostic, and predictive biomarkers for lung cancer. Genes Chromosomes Cancer (2012) 1.04
Evaluation of T7 and lambda phage display systems for survey of autoantibody profiles in cancer patients. J Immunol Methods (2008) 0.99
Sperm-associated antigens as targets for cancer immunotherapy: expression pattern and humoral immune response in cancer patients. J Immunother (2011) 0.94
Tumor-associated autoantibody signature for the early detection of gastric cancer. Int J Cancer (2012) 0.92
Manipulation of tumour-infiltrating B cells and tertiary lymphoid structures: a novel anti-cancer treatment avenue? Cancer Immunol Immunother (2014) 0.84
Prognostic relevance of carbonic anhydrase IX expression is distinct in various subtypes of breast cancer and its silencing suppresses self-renewal capacity of breast cancer cells. Cancer Chemother Pharmacol (2014) 0.83
Validity of multiplex biomarker model of 6 genes for the differential diagnosis of thyroid nodules. Thyroid Res (2011) 0.78
Ranking-based kernels in applied biomedical diagnostics using a support vector machine. Int J Neural Syst (2011) 0.75