Published in J Org Chem on January 21, 2005
Identification of somatically acquired rearrangements in cancer using genome-wide massively parallel paired-end sequencing. Nat Genet (2008) 43.63
A comprehensive catalogue of somatic mutations from a human cancer genome. Nature (2009) 24.27
A small-cell lung cancer genome with complex signatures of tobacco exposure. Nature (2009) 18.39
A large genome center's improvements to the Illumina sequencing system. Nat Methods (2008) 15.56
The patterns and dynamics of genomic instability in metastatic pancreatic cancer. Nature (2010) 12.43
Mutational processes molding the genomes of 21 breast cancers. Cell (2012) 11.22
The life history of 21 breast cancers. Cell (2012) 10.59
Development and validation of a clinical cancer genomic profiling test based on massively parallel DNA sequencing. Nat Biotechnol (2013) 7.97
Subclonal phylogenetic structures in cancer revealed by ultra-deep sequencing. Proc Natl Acad Sci U S A (2008) 7.22
Identification of new ALK and RET gene fusions from colorectal and lung cancer biopsies. Nat Med (2012) 6.77
Tissue macrophages act as cellular chaperones for vascular anastomosis downstream of VEGF-mediated endothelial tip cell induction. Blood (2010) 3.82
Targeted next-generation sequencing of advanced prostate cancer identifies potential therapeutic targets and disease heterogeneity. Eur Urol (2012) 2.39
Use of cancer-specific genomic rearrangements to quantify disease burden in plasma from patients with solid tumors. Genes Chromosomes Cancer (2010) 2.11
Next-generation sequencing reveals high concordance of recurrent somatic alterations between primary tumor and metastases from patients with non-small-cell lung cancer. J Clin Oncol (2013) 1.71
Next-generation sequencing identifies and immunohistochemistry confirms a novel crizotinib-sensitive ALK rearrangement in a patient with metastatic non-small-cell lung cancer. J Thorac Oncol (2012) 1.66
BRAF fusions define a distinct molecular subset of melanomas with potential sensitivity to MEK inhibition. Clin Cancer Res (2013) 1.66
New routes to targeted therapy of intrahepatic cholangiocarcinomas revealed by next-generation sequencing. Oncologist (2014) 1.61
Concordance of genomic alterations between primary and recurrent breast cancer. Mol Cancer Ther (2014) 1.57
Long-range Ca2+ waves transmit brain-damage signals to microglia. Dev Cell (2012) 1.46
Targeted genomic sequencing of pediatric Burkitt lymphoma identifies recurrent alterations in antiapoptotic and chromatin-remodeling genes. Blood (2012) 1.38
The determination of the absolute configurations of chiral molecules using vibrational circular dichroism (VCD) spectroscopy. Chirality (2008) 1.23
Simultaneous determination of 16 anti-HIV drugs in human plasma by high-performance liquid chromatography. J Chromatogr B Analyt Technol Biomed Life Sci (2006) 1.21
Clinical next-generation sequencing successfully applied to fine-needle aspirations of pulmonary and pancreatic neoplasms. Cancer Cytopathol (2013) 1.16
Secretory meningiomas are defined by combined KLF4 K409Q and TRAF7 mutations. Acta Neuropathol (2013) 1.15
Relapsed classic E-cadherin (CDH1)-mutated invasive lobular breast cancer shows a high frequency of HER2 (ERBB2) gene mutations. Clin Cancer Res (2013) 1.14
A high frequency of activating extracellular domain ERBB2 (HER2) mutation in micropapillary urothelial carcinoma. Clin Cancer Res (2013) 1.12
Massively parallel sequencing reveals the complex structure of an irradiated human chromosome on a mouse background in the Tc1 model of Down syndrome. PLoS One (2013) 1.10
Catalytic enantioselective Friedel-Crafts alkylation of indoles with nitroalkenes by using a simple thiourea organocatalyst. Angew Chem Int Ed Engl (2005) 1.08
Novel chromosomal rearrangements and break points at the t(6;9) in salivary adenoid cystic carcinoma: association with MYB-NFIB chimeric fusion, MYB expression, and clinical outcome. Clin Cancer Res (2011) 1.05
Microglia in the developing brain: from immunity to behaviour. Curr Opin Neurobiol (2011) 1.04
Directed palladation: fine tuning permits the catalytic 2-alkenylation of indoles. Chem Commun (Camb) (2005) 1.03
Bovine serum albumin-based magnetic nanocarrier for MRI diagnosis and hyperthermic therapy: a potential theranostic approach against cancer. Small (2010) 1.03
Identification of a novel HIP1-ALK fusion variant in Non-Small-Cell Lung Cancer (NSCLC) and discovery of ALK I1171 (I1171N/S) mutations in two ALK-rearranged NSCLC patients with resistance to Alectinib. J Thorac Oncol (2014) 1.02
Phase-transfer-catalyzed asymmetric aza-Henry reaction using N-carbamoyl imines generated in situ from alpha-amido sulfones. Angew Chem Int Ed Engl (2005) 0.95
Anastrozole and everolimus in advanced gynecologic and breast malignancies: activity and molecular alterations in the PI3K/AKT/mTOR pathway. Oncotarget (2014) 0.95
Synthesis and coating of cobalt ferrite nanoparticles: a first step toward the obtainment of new magnetic nanocarriers. Langmuir (2007) 0.94
Solvothermal synthesis and properties control of doped ZnO nanoparticles. J Colloid Interface Sci (2008) 0.94
Comprehensive genomic profiling of relapsed and metastatic adenoid cystic carcinomas by next-generation sequencing reveals potential new routes to targeted therapies. Am J Surg Pathol (2014) 0.91
Thymoma patients treated in a phase I clinic at MD Anderson Cancer Center: responses to mTOR inhibitors and molecular analyses. Oncotarget (2013) 0.89
Genomic profiling of advanced-stage, metaplastic breast carcinoma by next-generation sequencing reveals frequent, targetable genomic abnormalities and potential new treatment options. Arch Pathol Lab Med (2015) 0.89
Autophosphorylation and Pin1 binding coordinate DNA damage-induced HIPK2 activation and cell death. Proc Natl Acad Sci U S A (2013) 0.88
Animal models for studying microglia: the first, the popular, and the new. Glia (2012) 0.88
Risk of preterm delivery associated with prior treatment of cervical precancerous lesion according to the depth of the cone. Dis Markers (2013) 0.87
Organocatalytic trifluoromethylation of imines using phase-transfer catalysis with phenoxides. A general platform for catalytic additions of organosilanes to imines. Chem Commun (Camb) (2011) 0.87
Calcium channel antagonists discovered by a multidisciplinary approach. J Med Chem (2006) 0.85
Phase transfer catalyzed enantioselective Strecker reactions of alpha-amido sulfones with cyanohydrins. J Org Chem (2006) 0.85
Direct access to enantiomerically enriched alpha-amino phosphonic acid derivatives by organocatalytic asymmetric hydrophosphonylation of imines. J Org Chem (2006) 0.84
Study of mechanisms of chiral discrimination of amino acids and their derivatives on a teicoplanin-based chiral stationary phase. J Chromatogr A (2004) 0.84
Evaluation of a Congenital Infantile Fibrosarcoma by Comprehensive Genomic Profiling Reveals an LMNA-NTRK1 Gene Fusion Responsive to Crizotinib. J Natl Cancer Inst (2015) 0.83
Catalytic asymmetric Mannich reactions of sulfonylacetates. Angew Chem Int Ed Engl (2009) 0.82
Organocatalytic asymmetric Mannich reactions with N-Boc and N-Cbz protected alpha-amido sulfones (Boc: tert-butoxycarbonyl, Cbz: benzyloxycarbonyl). Chemistry (2007) 0.82
A chiral A2 B2 macrocyclic minireceptor with extreme enantioselectivity. Org Lett (2002) 0.81
Exceptional gas-phase enantioselectivity of chiral tetramide macrocycles. J Am Chem Soc (2005) 0.81
On-column epimerization of dihydroartemisinin: an effective analytical approach to overcome the shortcomings of the International Pharmacopoeia monograph. J Chromatogr B Analyt Technol Biomed Life Sci (2008) 0.80
Activity of c-Met/ALK Inhibitor Crizotinib and Multi-Kinase VEGF Inhibitor Pazopanib in Metastatic Gastrointestinal Neuroectodermal Tumor Harboring EWSR1-CREB1 Fusion. Oncology (2016) 0.80
Oxidative Intramolecular Coupling of Amidocuprates as a Novel Route to Amines and Hydrazines. J Org Chem (1996) 0.80
Evaluation of teicoplanin chiral stationary phases of 3.5 and 5 microm inside diameter silica microparticles by polar-organic mode capillary electrochromatography. Electrophoresis (2003) 0.80
Absolute configuration and biological profile of two thiazinooxadiazol-3-ones with L-type calcium channel activity: a study of the structural effects. Org Biomol Chem (2012) 0.79
Dynamic HPLC on chiral stationary phases: a powerful tool for the investigation of stereomutation processes. J Sep Sci (2006) 0.79
Design and evaluation of hydrolytically stable bidentate urea-type stationary phases for hydrophilic interaction chromatography. J Chromatogr A (2011) 0.79
Stereolability of dihydroartemisinin, an antimalarial drug: a comprehensive kinetic investigation. Part 2. J Org Chem (2011) 0.78
Internal motions in a fulleropyrrolidine tertiary amide with axial chirality. J Org Chem (2004) 0.78
HPLC chiral stationary phases containing macrocyclic antibiotics: practical aspects and recognition mechanism. Adv Chromatogr (2008) 0.78
Gas-phase enantioselective reactions in noncovalent ion-molecule complexes. Chirality (2009) 0.78
Organocatalytic asymmetric formal [3 + 2] cycloaddition with in situ-generated N-carbamoyl nitrones. J Am Chem Soc (2009) 0.78
Bioinspired organocatalytic asymmetric reactions. Org Biomol Chem (2012) 0.78
Analysis of bovine milk caseins on organic monolithic columns: an integrated capillary liquid chromatography-high resolution mass spectrometry approach for the study of time-dependent casein degradation. J Chromatogr A (2013) 0.78
Catalytic asymmetric conjugate addition of nitroalkanes to 4-nitro-5-styrylisoxazoles. Angew Chem Int Ed Engl (2009) 0.77
Prismatomerin, a new iridoid from Prismatomeris tetrandra. Structure elucidation, determination of absolute configuration, and cytotoxicity. J Nat Prod (2007) 0.77
Enantiomerization of chiral uranyl-salophen complexes via unprecedented ligand hemilability: toward configurationally stable derivatives. J Org Chem (2008) 0.77
Organocatalyzed solvent-free aza-Henry reaction: a breakthrough in the one-pot synthesis of 1,2-diamines. J Org Chem (2004) 0.77
Concise and stereocontrolled synthesis of pseudo-C2-symmetric diamino alcohols and triamines for use in HIV protease inhibitors. J Org Chem (2003) 0.77
Stereomutations of atropisomers of sterically hindered salophen ligands. J Org Chem (2005) 0.77
Regio- and Stereochemical Aspects of the Palladium-Catalyzed Desilylation-Arylation of Substituted Vinylsilanes. J Org Chem (1996) 0.77
Comparison of time-dependent density-functional theory and coupled cluster theory for the calculation of the optical rotations of chiral molecules. J Phys Chem A (2008) 0.76
CeCl(3) x 7H(2)O-NaI catalyzed hydrooxacyclization of unsaturated 3-hydroxy esters. Org Lett (2002) 0.76
Organocatalytic asymmetric Povarov reactions with 2- and 3-vinylindoles. Chem Commun (Camb) (2009) 0.76
Organocatalytic asymmetric Diels-Alder reactions of 3-vinylindoles. Angew Chem Int Ed Engl (2008) 0.76
Stereoselective behavior of the functional diltiazem analogue 1-[(4-chlorophenyl)sulfonyl]-2-(2-thienyl)pyrrolidine, a new L-type calcium channel blocker. J Med Chem (2009) 0.76
Comprehensive Genomic Profiling of Clinically Advanced Medullary Thyroid Carcinoma. Oncology (2016) 0.75
Francesca Peri: Micromanaging the lives of microglia. J Cell Biol (2015) 0.75
A new simple procedure for discriminating between deracemization and an induced CD Effect in chiral recognition experiments on atropoisomers. Org Lett (2004) 0.75